Clinical trials: Renal Insufficiency, Acute
Magnesium Disorder
The Relationship Between Preoperative Levels of Ionized Magnesium and Risk of Acute Kidney Injury After Cardiac Surgery
Detection the relationship between preoperative ionized magnesium levels and the risk of acute kidney injury after cardiac surgery.
- Trial name
- NCT05903677
- Testing
- magnesium levels
- Volunteers
- 50 people
- Sponsor
- Assiut University
Acute Coronary Syndrome, Renal Insufficiency
Remote Ischemic Preconditioning in ACS Patients
Remote ischemic preconditioning is a process of serial blood pressure cuff inflations and deflations that are performed prior to a procedure and have been shown in various other areas (coronary bypass surgery, vascular surgery…
- Conditions
- Acute Coronary Syndrome, Renal Insufficiency, Ischemia, Myocardial
- Trial name
- NCT03329612
- Testing
- Remote Ischemic Preconditioning
- Where
- United States
- Sponsor
- Henry Ford Health System
Delirium, Acute Kidney Injury
Neurocognitive Outcomes for ICU Patients With Acute Kidney Injury
Introduction. Initiation of acute kidney replacement therapy (KRT) is common in critically ill adults admitted to the intensive care unit (ICU), and is associated with increased morbidity and mortality.
- Conditions
- Delirium, Acute Kidney Injury, Critical Illness, Cognitive Impairment
- Trial name
- INCOGNITOAKI (NCT04722939)
- Testing
- Cerebral oxygenation
- Where
- Canada
- Volunteers
- 104 people
- Sponsor
- Dr. Gordon Boyd
Chronic Kidney Diseases, Acute Coronary Syndrome
Study Comparing Treatment Effectiveness of Guideline Indicated APT for ACS in Patients With CKD
To compare clinical outcomes in patients with chronic kidney disease (CKD) presenting with an acute coronary syndrome (ACS) treated with clopidogrel or ticagrelor (both FDA approved and guideline indicated drugs for treating…
- Trial name
- CPRS-CKD (NCT03150667)
- Testing
- Ticagrelor, Clopidogrel
- Where
- 2 sites in United States
- Volunteers
- 220 people
- Sponsor
- North Texas Veterans Healthcare System
Severe Sepsis, Shock, Septic
L-carnitine as an Adjunct Treatment for Septic Shock Patients With Acute Kidney Injury
The primary objective of this study is to compare 28 day mortality rates between septic shock patients with acute renal insufficiency treated via L-Carnitine (as an adjunct therapy) versus a similar group of patients not…
- Conditions
- Severe Sepsis, Shock, Septic, Acute Kidney Injury
- Trial name
- CarniSave (NCT02664753)
- Testing
- 56 days of weight-adjusted L-Carnitine treatment
- Where
- 11 sites in France
- Volunteers
- 254 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Acute Kidney Injury, Cardiac Surgery
Kidney Oxygen Saturation and Neutrophil Gelatinase-associated Lipocalin (NGAL) for Detecting Acute Kidney Injury (AKI) After Cardiac Surgery
Acute kidney injury (AKI) is an important complication following cardiac surgery with cardiopulmonary bypass (CPB). Early identification of patients at risk of AKI may facilitate timely clinical management.
- Conditions
- Acute Kidney Injury, Cardiac Surgery, Cardiopulmonary Bypass
- Trial name
- NCT07837037
- Testing
- Renal Near-Infrared Spectroscopy Monitoring, Neutrophil Gelatinase-Associated Lipocalin (NGAL) Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Haseki Training and Research Hospital
Acute Kidney Injury
Renal Replacement Therapy and In-Hospital Mortality Incidence in Cardiac Surgery Associated Acute Kidney Injury
The goal of this study is to analyse the relation of severe acute kidney injury post cardiac surgery which characterised by the need of renal replacement therapy, with in-hospital postoperative mortality incidence.
- Trial name
- NCT06091982
- Testing
- Renal Replacement Therapy (RRT)
- Where
- Indonesia
- Volunteers
- 1,113 people
- Sponsor
- National Cardiovascular Center Harapan Kita Hospital Indonesia
Heart Failure
The Use of Tolvaptan to Prevent Renal Dysfunction in High Risk Patients With Heart Failure-Pilot Study
It is well known that the use of loop diuretics in acute setting may decrease glomerular filtration rate (GFR) and increase serum creatinine leading to renal dysfunction.
- Trial name
- NCT01663662
- Testing
- Tolvaptan
- Where
- United States
- Sponsor
- University of Michigan
Acute Decompensated Heart Failure (ADHF), Cardiorenal Syndrome (CRS)
Clinical Outcomes of Levosimendan Versus Dobutamine Versus Milrinone in Cases With Acute Decompensated Heart Failure With Impaired Renal Function
This study aimed to assess and compare the cardiac, renal, and clinical efficacy of Levosimendan (LEV), Dobutamine (DOB), and milrinone (MIL) in cases with acute decompensated heart failure (ADHF) complicated by renal impairment…
- Trial name
- NCT07186062
- Testing
- Levosimendan, Dobutamine, Milrinone
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Covid19, Acute Kidney Injury
Urine Alkalinisation in COVID-19
Since the outbreak of coronavirus disease 2019 (COVID-19), more than 100,000 patients have died in the United Kingdom. Acute kidney injury is common in critically ill patients with COVID-19.
- Trial name
- NCT04806061
- Testing
- Sodium bicarbonate, standard care
- Where
- 2 sites in United Kingdom
- Volunteers
- 80 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery Requiring Extracorporeal Circulation
Role of Mitochondrial Dysfunction in the Occurrence of Acute Kidney Injury (AKI) in Postoperative Cardiac Surgery
Cardiac Surgery and Acute Kidney Failure (AKI) post Surgery: AKI is a frequent complication in the immediate aftermath of cardiac surgery with an incidence varying from 5 to 40%.
- Trial name
- MIT-CEC (NCT04125069)
- Testing
- Coronary Artery Bypass Graft (CABG)
- Where
- France
- Volunteers
- 27 people
- Sponsor
- University Hospital Center of Martinique
COVID, AKI
Epidemiology of Acute Kidney Injury in COVID19 Disease in United Kingdom
Severe Acute respiratory syndrome coronovirus (SARS-CoV-2) was first described in Wuhan in December 2019. It quickly spread to rest of the world and was declared pandemic by World health organisation.
- Trial name
- NCT04407156
- Testing
- acute kidney injury
- Where
- United Kingdom
- Volunteers
- 724 people
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
END STAGE RENAL DISEASE
ESTEROID WITHDRAWAL STUDY, SAFETY AND EFFICACY IN RENAL TRANPLANTATION
BACKGROUND: Non-steroid maintenance immunosuppression after transplantation can improve long-term lipid and hemodynamic profiles without severe acute rejection (AR) events that alter graft function or survival.
- Trial name
- ESWMEX001 (NCT02328222)
- Testing
- ESW group
- Where
- Mexico
- Volunteers
- 71 people
- Sponsor
- Unidad de Investigacion Medica en Enfermedades Renales
Acute Kidney Injury
Personalized Versus Standard Hydration for Prevention of CI-AKI: a Randomized Trial With Bioimpedance Analysis
The aim of this study was to evaluate, in patients with "lower fluid status" defined by bioimpedance analysis, whether two different protocol of IV isotonic saline infusion are associated with different volume expansion and…
- Trial name
- NCT02225431
- Testing
- sodium chloride infusion
- Where
- Italy
- Volunteers
- 296 people
- Sponsor
- Ospedale Misericordia e Dolce
Acute Kidney Injury
Renal Oxygen Saturation During Off-pump Coronary Artery Bypass Graft Surgery
The purpose of this study is to evaluate changes in renal oxygen saturation (rrSO2) and its relationship with central venous oxygen saturation (cvSO2), cerebral cortical oxygen saturation (rcSO2), and hemodynamic parameters while…
- Trial name
- OPCAB (NCT04679337)
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Yeungnam University College of Medicine
Heart Failure
Effectiveness of Ultrafiltration in Treating People With Acute Decompensated Heart Failure and Cardiorenal Syndrome (The CARRESS Study)
Heart failure is a serious condition in which the heart's ability to pump blood through the body is impaired, often making a person feel weak or fatigued.
- Trial name
- CARRESS (NCT00608491)
- Testing
- Stepped pharmacologic care, Ultrafiltration
- Where
- 9 sites in United States, Canada
- Volunteers
- 188 people
- Sponsor
- Duke University
Acute Kidney Injury, Congenital Heart Disease
Acute Kidney Injury After Cardiac Surgery on CPB
The purpose of this retrospective study is to determine the incidence and severity of acute kidney injuries (AKI) after heart surgery on cardiopulmonary bypass (CPB) in the pediatric intensive care unit (PICU) in Lausanne…
- Conditions
- Acute Kidney Injury, Congenital Heart Disease, Surgery, CBP
- Trial name
- NCT03513718
- Where
- Switzerland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Sepsis, Acute Kidney Injury Due to Sepsis
Presepsin:Gelsolin Ratio in Sepsis-related Organ Dysfunction
In the present study, 126 patients were enrolled (23 control, 38 non-septic and 65 septic patients). Blood samples were collected from septic patients at the intensive care unit (ICU) at three time points (T1-3): T1: within 12h…
- Conditions
- Sepsis, Acute Kidney Injury Due to Sepsis, Septic Shock, Acute Respiratory Distress Syndrome
- Trial name
- NCT05060679
- Testing
- Supportive therapy at the ICU, Sepsis therapy, Sepsis-related organ dysfunction therapy
- Where
- Hungary
- Volunteers
- 126 people
- Sponsor
- University of Pecs
Arrhythmia, Acute Kidney Injuries
This is an Observational Study That Aims to Demonstrate Postoperative Risk Factors in Pediatric Cardiac Surgery
This retrospective observational study aims to identify risk factors for postoperative complications in children undergoing cardiac surgery at a tertiary hospital in Brazil.
- Conditions
- Arrhythmia, Acute Kidney Injuries, Sepsis, Pneumopathy
- Trial name
- PEDS-CARE (NCT06985082)
- Testing
- THERE IS NOT A INTERVENTION
- Volunteers
- 310 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Diuretic Toxicity, Acute Kidney Injury
Risk Factors and Machine Learning Model for Diuretics Related Acute Kidney Injury
Acute kidney injury (AKI) is a series of clinical syndromes in which serum creatinine (Scr) concentrations increase over a short period of time, or urine output decreases.
- Trial name
- NCT05527054
- Testing
- Diuretics
- Where
- China
- Volunteers
- 18,000 people
- Sponsor
- Qianfoshan Hospital
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