Clinical trials: Renal Insufficiency, Acute
Azotemia, Renal Insufficiency, Chronic
Sensitivity and Specificity of NGAL in an Emergency Room Population
Hypothesis: In patients that present to an urban emergency room, a single urine neutrophil gelatinase-associated lipocalin (NGAL) measurement can classify their kidney disease as stable chronic kidney disease, acute tubular…
- Conditions
- Azotemia, Renal Insufficiency, Chronic, Renal Failure, Acute, Hydronephrosis
- Trial name
- NCT00786708
- Where
- 3 sites in United States, Germany
- Volunteers
- 2,304 people
- Sponsor
- Columbia University
Acute Kidney Injury, Renal Insufficiency, Acute
Effects of Levosimendan in Acute Kidney Injury After Cardiac Surgery
Acute kidney injury (AKI) is a common complication after cardiac surgery. Mismatch in renal oxygen demand-supply may be an important pathogenetic factor.
- Trial name
- LEVOAKI (NCT02531724)
- Testing
- Levosimendan
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Sahlgrenska University Hospital
Acute Kidney Injury, Acute Renal Failure
Minimizing Contrast Utilization With IVUS Guidance in Coronary Angioplasty to Avoid Acute Nephropathy
Contrast-induced acute kidney injury (CI-AKI) is an important adverse effect of percutaneous coronary interventions. Despite various efforts, very few preventive measures have been shown effective in reducing its incidence.
- Conditions
- Acute Kidney Injury, Acute Renal Failure, Acute Renal Injury
- Trial name
- Mozart-II (NCT02743156)
- Testing
- IVUS-guided PCI, Angiography-guided PCI
- Where
- 2 sites in Brazil, Spain
- Volunteers
- 300 people
- Sponsor
- InCor Heart Institute
Acute Lung Injury, Adult Respiratory Distress Syndrome
Airway Pressure Release Ventilation (APRV) Compared to ARDSnet Ventilation
Traditional modes of ventilation have failed to improve patient survival. Subsequent observations that elevated airway pressures observed in traditional forms of ventilation resulted in barotrauma and extension of ALI lead to the…
- Conditions
- Acute Lung Injury, Adult Respiratory Distress Syndrome, Kidney Injury
- Trial name
- PRESSURE (NCT00793013)
- Testing
- Volume-Cycled Assist-Control (AC) mode, Airway Pressure Release Ventilation (APRV) mode
- Where
- United States
- Sponsor
- University of Tennessee, Chattanooga
Sepsis, Kidney Failure, Acute
Effects of HIgh Volume COntinuous REnal Replacement Therapy in Patients With Septic Acute Kidney Injury
Acute kidney injury (AKI) is a common and serious problem in critically ill patients, and is known to be an independent risk factor for mortality.
- Conditions
- Sepsis, Kidney Failure, Acute, Renal Replacement Therapy
- Trial name
- HICORES (NCT01191905)
- Testing
- high dose CRRT, Conventional dose CRRT
- Where
- 5 sites in South Korea
- Volunteers
- 212 people
- Sponsor
- Seoul National University Hospital
Acute Kidney Injury, Continuous Venovenous Hemofiltration
Bionenergetic Balance During CVVH
The bioenergetic balance is the sum of energy exchanged during CRRT and is mostly defined by citrate glucose and lactate. When CRRT was performed with the older dialysis fluids, glucose and lactate could be an important source of…
- Conditions
- Acute Kidney Injury, Continuous Venovenous Hemofiltration, Energy Metabolism, Resting Energy Expenditure
- Trial name
- BALANCE (NCT06483542)
- Testing
- bioenergetic balance
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Universitair Ziekenhuis Brussel
Acute Kidney Injury, Cardiac Surgery
Acute Kidney Injury After Cardiac Surgery
Acute kidney injury (AKI) is common after cardiac surgery. The diagnosis is based on the criteria defined by the Kidney Disease Improving Global Outcomes (KDIGO) classification: oliguria and elevation of serum creatinine.
- Trial name
- NEPHROCAR (NCT03396770)
- Testing
- Standard clinical routine, Nephrocheck test
- Where
- France
- Volunteers
- 848 people
- Sponsor
- Rennes University Hospital
Akut Kidney Injury
The Role of Furosemide Stress Test in the Intensive Care Clinic
AKI causes high mortality and morbidity, especially in critically ill patients, and prolongs the patient's stay in the intensive care unit.
- Trial name
- NCT06765031
- Testing
- Furosemide
- Where
- Turkey (Türkiye)
- Volunteers
- 121 people
- Sponsor
- Gulhane Training and Research Hospital
Venous Thromboembolic Disease, Kidney Failure, Chronic
Anticoagulation Strategies for Acute Venous Thromboembolism in Patients With End-Stage Renal Disease Using USRDS Data
Patients with end stage renal disease (ESRD) are at significantly increased risk of thrombosis and bleeding relative to those with normal renal function which makes anticoagulation particularly challenging.
- Trial name
- NCT04818151
- Testing
- Warfarin, Apixaban
- Where
- United States
- Volunteers
- 14,914 people
- Sponsor
- Johns Hopkins University
Acute Kidney Injury
Arterial Stiffness and AKI Post-CABG
Acute Kidney Injury is a condition where your kidneys suddenly stop working properly and usually occurs if you are already unwell with an illness and can happen after having surgery.
- Trial name
- Heart-AKI (NCT02364427)
- Testing
- Arterial stiffness - Vicorder to measure pulse wave velocity
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- King's College Hospital NHS Trust
Acute Kidney Injury
Dialysis Weaning in Intensive Care Units (Dialysis STOP)
Evaluation of daily urinary urea excretion, to guide Renal Replacement Therapy weaning, in Intensive Care Units. The objective is to show that remove the dialysis catheter, once daily urinary urea excretion is greater than 1.35…
- Trial name
- D-STOP (NCT03763188)
- Testing
- Use of daily urinary urea excretion
- Where
- France
- Volunteers
- 260 people
- Sponsor
- Dr Alexandre Gros
Acute Kidney Injury
Goal Directed Therapy for Acute Kidney Injury in Critical Ill Patients
Acute kidney injury (AKI) is a frequent complication in critically ill patients admitted to intensive care unit (ICU) and it is associated with increased morbimortality.
- Trial name
- GDT-AKIN (NCT02414906)
- Testing
- Goal-directed therapy
- Volunteers
- 99 people
- Sponsor
- Barretos Cancer Hospital
Acute Kidney Injury
Preoperative Prediction of Acute Kidney Injury After Cardiac Surgery
Although acute kidney injury (AKI) frequently complicates cardiac surgery, methods to determine AKI risk are lacking. Renal functional reserve (RFR), the capacity of the intact nephron mass to increase glomerular filtration rate…
- Trial name
- RFR (NCT03092947)
- Testing
- No intervention
- Volunteers
- 110 people
- Sponsor
- University of Giessen
Acute Kidney Injury, Contrast-induced Nephropathy
Clinical Validation of the RENISCHEM L-FABP POC Assay
This study will involve measurement of levels of a novel urinary biomarker of renal ischemia, L-FABP. The purpose of the study is to perform a clinical validation of the ability of L-FABP measurements in urine using the RENISCHEM…
- Trial name
- SAKURA-POC (NCT04864847)
- Testing
- RENISCHEM L-FABP POC Test
- Where
- 6 sites in United States
- Volunteers
- 382 people
- Sponsor
- Hikari Dx, Inc.
Acute Cellular Graft Rejection, Liver Transplant Rejection
Budesonide for Immunosuppression After Liver Transplantation to Reduce Side Effects
Our hypothesis is that budesonide will provide effective hepatic ISP that will replace prednisone and allow lower systemic drug levels of FK, thus reducing the steroid- and calcineurin-associated complications often observed in…
- Trial name
- BILT (NCT03315052)
- Testing
- Budesonide, Tacrolimus（FK506）, Mycophenolate Mofetil
- Sponsor
- Montefiore Medical Center
Acute Kidney Injury (AKI)
Precision-Medicine Diagnostic Support in Hospitalized Veterans With Acute Kidney Injury
Acute kidney injury (AKI) affects up to 20% of hospitalized Veterans and is strongly associated with morbidity and death. AKI is a diverse condition and timely and accurate diagnosis of the type of AKI is critical to begin…
- Trial name
- PRECISE-AKI (NCT07217808)
- Testing
- PRECISE-AKI Clinical Decision Support Tool
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- VA Office of Research and Development
Acute Kidney Injury (Nontraumatic), Critical Illness
Impact of CRRT on Serum Carnitine and Micronutrient Levels
This study aims to investigate the changes in blood levels of micronutrients and carnitine in critically ill patients with Acute Kidney Injury (AKI) who are undergoing Continuous Renal Replacement Therapy (CRRT).
- Trial name
- NCT07467889
- Testing
- Continuous Renal Replacement Therapy (CRRT), Standard of Care (Non-CRRT Management)
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Gulhane Training and Research Hospital
Sepsis, Acute Renal Failure
Super High-Flux - High Volume Dialysis in Sepsis-Induced Acute Renal Failure
Patients within the intensive care unit who have severe infections causing shock and kidney failure have almost a 60% risk of dying despite antibiotic therapy, surgical drainage of the site of infection and intensive care support…
- Trial name
- NCT00333593
- Testing
- Large pore dialyser, Standard dialyser
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- Austin Health
COVID19, ARDS
Follow-up of Critical COVID-19 Patients
The study will follow COVID-19 patients who required intensive care after 3-6 months and one year after discharge from the ICU with functional level as well as organ function to assess recovery after COVID-19.
- Conditions
- COVID19, ARDS, AKI, Circulatory Failure
- Trial name
- FUP-COVID (NCT04474249)
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Uppsala University
Dyspnea, Chronic Renal Failure
POCUS VS CT in Diagnosis of Acute Dyspnea in Chronic Hemodialysis Patients
Estimate the predictive value of POCUS in diagnosis of different causes of acute dyspnea in hemodialysis patients and compare between POCUS and CT in differentiation the causes of acute dyspnea in those population.
- Trial name
- NCT05729035
- Testing
- POCUS
- Volunteers
- 100 people
- Sponsor
- Randa Ahmed Sarhan
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.