Clinical trials: Renal Insufficiency, Acute
Acute Kidney Injury, Children
Renal Oxygen Saturation and Its Association With Acute Renal Injury
Peri-operative renal dysfunction is a major mortality and morbidity cause following cardiac and major vascular surgery. Although several intra-operative strategies are proposed for better outcomes, no effective and fast resulting…
- Conditions
- Acute Kidney Injury, Children, Cardiac Surgery
- Trial name
- NCT03608956
- Where
- Turkey (Türkiye)
- Sponsor
- Marmara University
Acute Kidney Injury
Midodrine is Effective in Management of Intradialytic Hypotension Among Critically-ill Patients With Acute Kidney Injury
The aim of this randomized trial was to assess the efficacy of oral midodrine tablets for the management of intradialytic hypotension among critically ill patients with acute kidney injury.
- Trial name
- NCT03431194
- Testing
- midodrine
- Volunteers
- 80 people
- Sponsor
- Benha University
Thrombotic Microangiopathy, Acute Kidney Injury
French National Cohort MATRIX "Renal and Systemic Thrombotic Microangiopathy"
Thrombotic microangiopathies (TMAs) are a diverse, rare but serious group of diseases. Progress has been made regarding the epidemiology of TMA (Bayer CJASN 2019).
- Conditions
- Thrombotic Microangiopathy, Acute Kidney Injury, Hemolytic Uremic Syndrome, Nephrology
- Trial name
- MATRIX (NCT05991245)
- Testing
- Collecting datas
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Tours
Urolithiasis
COMPARISON OF FANS VS CONVENTIONAL URETERAL ACCESS SHEATH in RIRS on POSTOPERATIVE ACUTE KIDNEY INJURY
Kidney stone disease is a common condition, and retrograde intrarenal surgery (RIRS) is a minimally invasive procedure frequently used to remove kidney stones.
- Trial name
- FANS (NCT07685587)
- Testing
- flexible and navigable ureteral access sheath, conventional ureteral access sheath
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Namik Kemal University
Acute Kidney Injury, Sepsis
Galectin-3 in Septic and Non-septic Acute Kidney Injury
Acute kidney injury (AKI) is a common critical condition with high morbidity and mortality. The level of circulating Galectin-3 (Gal3) largely depends on renal function, so it is elevated in patients with AKI or CKD; elevated…
- Trial name
- NCT05691621
- Testing
- Standard Reagents, Whole Blood
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Fengyun Wang
Cirrhosis, Acute on Chronic Hepatic Failure
Single Pass Albumin Dialysis in Patients With Cirrhosis
The aim of this study is to determine whether a simplified device of albumin dialysis also has beneficial effects.
- Conditions
- Cirrhosis, Acute on Chronic Hepatic Failure, Hepatorenal Syndrome, Encephalopathy
- Trial name
- DACAR (NCT00764049)
- Testing
- Single pass albumin dialysis
- Where
- France
- Volunteers
- 11 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hernia, Ventral, Hernia Incisional
Renal- and Pulmonary Function in Relation to Abdominal Hypertension After Abdominal Reconstruction
An incisional hernia is technically challenging to operate and is the most frequent long-term complication after open surgery, resulting in impaired quality of life and reduced physical ability.
- Conditions
- Hernia, Ventral, Hernia Incisional, Acute Kidney Injury, Restrictive Lung Disease
- Trial name
- REPARE (NCT04143776)
- Testing
- Abdominal reconstruction
- Where
- Denmark
- Sponsor
- Bispebjerg Hospital
Acute Kidney Injury
Acute Kidney Injury - Biomarkers in Major Abdominal Surgery
To validate Urinary Biomarkers for the prediction of AKI in major abdominal surgery patients
- Trial name
- AKI-BioMAS (NCT04582747)
- Testing
- Urinary Biomarkers (NGAL, DKK-3, IGFBP-7/TIMP-2, KIM-1)
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust
Acute Kidney Injury
Guidance of Ultrasound in Intensive Care to Direct Euvolemia
The purpose of this study is to assess the effectiveness of routine ultrasound assessments of volume status and fluid responsiveness for goal-directed therapy (GDT)-based fluid resuscitation in reducing acute kidney injury (AKI)…
- Trial name
- GUIDE (NCT03938038)
- Testing
- Serial ultrasound assessments for GDT, Usual care
- Where
- United States
- Volunteers
- 415 people
- Sponsor
- The University of Texas Health Science Center, Houston
Renal Insufficiency, Acute
Evaluation of the Renal Function in an Ultra-endurance Race.
During ultra endurance events, athletes experience extreme physical and mental demands, sometimes at the limits of the adaptive response to human physiology.
- Trial name
- INFERNAL (NCT03136315)
- Testing
- INFERNAL Intervention
- Where
- France
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Chronic Kidney Diseases, Acute Coronary Syndrome
Study Comparing Treatment Effectiveness of Guideline Indicated APT for ACS in Patients With CKD
To compare clinical outcomes in patients with chronic kidney disease (CKD) presenting with an acute coronary syndrome (ACS) treated with clopidogrel or ticagrelor (both FDA approved and guideline indicated drugs for treating…
- Trial name
- CPRS-CKD (NCT03150667)
- Testing
- Ticagrelor, Clopidogrel
- Where
- 2 sites in United States
- Volunteers
- 220 people
- Sponsor
- North Texas Veterans Healthcare System
Pneumonia, Syncope
Quasi-Randomized Evaluation of the UCLA Next Day Clinic (NDC)
The Next Day Clinic (NDC) is a quality improvement initiative that will be launched and operated by UCLA Health starting July 22, 2024. Its goals are to improve patient care and safety and to maximize cost effectiveness.
- Conditions
- Pneumonia, Syncope, Congestive Heart Failure, Cellulitis
- Trial name
- NDC (NCT06526884)
- Testing
- Next Day Clinic
- Where
- United States
- Volunteers
- 570 people
- Sponsor
- University of California, Los Angeles
Acute Kidney Injury Due to Circulatory Failure (Disorder)
The Effects of Oxiris on Systemic Inflammation and Endothelial dysFunction
CS-AKI occurring in 20% to 70% of cases depending of the type of cardiac surgery. The systemic inflammatory response is often observed and associated with increased risk of AKI.
- Trial name
- EOSIEF (NCT04257006)
- Testing
- oXiris membrane
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- St. Petersburg State Pavlov Medical University
Acute Kidney Failure
Prostacyclin's Effect on Platelet Responsiveness
The researchers investigated the influence of a prostacyclin analogue (PGIA) versus unfractionated heparin (UFH) on ex vivo platelet function, during continuous venovenous hemodiafiltration.
- Trial name
- NCT00890214
- Testing
- prostacyclin, heparin
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- Catholic University of the Sacred Heart
Acute Kidney Injury, Intra-Abdominal Hypertension
Cumulative Intra-Abdominal Pressure Burden and Acute Kidney Injury After Emergency Abdominal Surgery
The goal of this observational study is to learn whether increased pressure inside the abdomen over time is associated with acute kidney injury in adults receiving intensive care after emergency abdominal surgery.
- Trial name
- IAP-AKI (NCT07891026)
- Testing
- Serial Intra-Abdominal Pressure Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Ugur Duman
Acute Kidney Injury, Renal Insufficiency, Acute
VExUS-guided Fluid Management in Patients With Acute Kidney Injury in the Intensive Care Unit
A quasi experimental study that aims to verify whether the incorporation of VExUS in patients with AKI in the Intensive Care Unit (ICU) may prompt tailored interventions to increases the number of days free from Renal Replacement…
- Conditions
- Acute Kidney Injury, Renal Insufficiency, Acute, Kidney; Disease, Acute, Critical Illness
- Trial name
- AKIVEX (NCT05240833)
- Testing
- VExUS Score
- Where
- Brazil
- Volunteers
- 55 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Renal Insufficiency, Acute, Renal Replacement Therapy
Intermittent Versus Continuous Renal Replacement Therapy for Acute Renal Failure
This multicentre SHARF4 (Stuivenberg Hospital Acute Renal Failure) study aims to investigate outcome in patients with acute renal failure (ARF), stratified according to severity of disease (SHARF score) and randomised to…
- Trial name
- NCT00322933
- Testing
- renal replacement therapy (intermittent or continuous)
- Where
- Belgium
- Volunteers
- 1,628 people
- Sponsor
- Ziekenhuis Netwerk Antwerpen (ZNA)
Acute Kidney Injury, Chemotherapy
Prediction of Kidney Injury After Hyperthermic Intraperitoneal Chemotherapy (HIPEC)* With Machine Learning
Patients undergoing cytoreductive surgery with hyperthermic intraoperative chemotherapy (CRS with HIPEC) are prone to postoperative kidney dysfunction.
- Trial name
- HIPEC (NCT03895606)
- Testing
- Data collection
- Where
- South Korea
- Volunteers
- 57 people
- Sponsor
- Gangnam Severance Hospital
Acute Kidney Injury, Renal Insufficiency, Chronic
Safety of Iodinated Contrast in Liver Transplant Candidates With Decreased Renal Function Undergoing Coronary CT Angiography
This study evaluates the safety of iodinated contrast medium administered to liver transplant candidates with decreased renal function undergoing coronary CT angiography.
- Conditions
- Acute Kidney Injury, Renal Insufficiency, Chronic, Contrast-induced Nephropathy, Liver Transplantation
- Trial name
- NCT03806725
- Testing
- Intravenous administration of iodinated contrast medium for coronary CT angiography
- Where
- United States
- Sponsor
- Stanford University
Contrast Induced Nephropathy, Acute Renal Failure
Cystatin C as an Early Marker of Contrast-Medium Nephropathy in Cardiac Catheterization Patients
Hypothesis: Cystatin C compared with creatinine is a better and earlier marker of contrast-induced nephropathy in high and intermedium risk cardiac catheterization patients.
- Trial name
- NCT00467311
- Where
- Mexico
- Volunteers
- 66 people
- Sponsor
- National Heart Institute, Mexico
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