Clinical trials: Renal Insufficiency, Acute
Kidney Transplantation, Acute Kidney Tubular Necrosis
Effect of BM-MSCs on Early Graft Function Recovery After DCD Kidney Transplant.
This study is designed to investigate whether allogeneic bone marrow-derived mesenchymal stem cells (BM-MSCs) can promote function recovery in patients with poor early graft function after kidney transplantation from Chinese…
- Trial name
- NCT02563366
- Testing
- BM-MSCs, Saline
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Kidney Failure, Acute, Renal Replacement Therapy
Use of Bicarbonate to Reduce the Incidence of Acute Renal Failure After Cardiac Surgery
The purpose of this study is to determine if the incidence of acute renal failure (ARF) in high risk patients who undergo coronary artery bypass grafting (CABG) is reduced by treating patients in the perioperative period with…
- Trial name
- NCT00484354
- Testing
- Sodium bicarbonate, Normal saline, Bicarbonate
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Wake Forest University Health Sciences
ST Elevation (STEMI) Myocardial Infarction, Contrast Induced Nephropathy (CIN)
Beyond the Mehran Risk Score: Predictive Value of Total Ischemic Time for Contrast-Induced Nephropathy in ST Segment Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention.
Contrast-Induced Nephropathy (CIN) is a serious complication following primary percutaneous coronary intervention (PCI) in patients presenting with acute ST-segment elevation myocardial infarction (STEMI).
- Conditions
- ST Elevation (STEMI) Myocardial Infarction, Contrast Induced Nephropathy (CIN), Acute Kidney Injury
- Trial name
- NCT07826572
- Testing
- Total Ischemic Time Evaluation
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assiut University
Critically Ill Patients, Nutritional Support
Impact of Comprehensive Rehabilitation Nursing Combined With Refined Airway Management and Nutritional Support on Prognosis and Care Delivery Models in Critically Ill Patients
This combined intervention protocol effectively improves the prognosis of critically ill patients and optimizes nursing management models
- Conditions
- Critically Ill Patients, Nutritional Support, Pulmonary Infections, Gastrointestinal Bleeding
- Trial name
- NCT07025941
- Testing
- Standard Critical Care Nursing Protocol, ICU-PRO Nursing Protocol (Integrated Critical Care Protocol for Rehabilitation Outcomes)
- Where
- China
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Taizhou Hospital of Traditional Chinese Medicine
Contrast-induced Nephropathy, Acute Kidney Injury
Proenkephalin for Prediction of Contrast-Associated Kidney Events
Currently, contrast-induced kidney injury cannot be diagnosed on the day of cardiac catheterization. Recently, proenkephalin (penKid) was introduced as a new glomerular filtration marker.
- Conditions
- Contrast-induced Nephropathy, Acute Kidney Injury, Coronary Artery Disease
- Trial name
- PANCAKE (NCT03989505)
- Testing
- blood-draw for biomarker analyses
- Where
- Germany
- Volunteers
- 220 people
- Sponsor
- Dr. med. Mahir Karakas
Acute Kidney Failure
Diagnosis of Acute Obstructive Renal Failure by Clinical Ultrasound Performed by the Emergency Physician.
Acute renal failure is frequently diagnosed in the emergency room during a biological assessment. Its discovery requires determining the cause, which may be either functional, or obstructive.
- Trial name
- IRASMU (NCT06190522)
- Testing
- Emergency physician clinical ultrasound
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Toulouse
Acute Kidney Injury
Renal Doppler Ultrasound in Early Detection of Acute Kidney Injury in Critically Ill Patients
Acute kidney injury is a common complication of critical illness and is associated with high morbidity and mortality .Acute kidney injury is a syndrome that is characterized by a rapid decline in renal function and urine output…
- Trial name
- NCT03902483
- Testing
- renal doppler ultrasound
- Volunteers
- 80 people
- Sponsor
- Assiut University
Type 2 Diabetes Mellitus, Acute Kidney Injury
Clinical Decision Support for SGLT2i After AKI in Type 2 Diabetes
This pilot study will evaluate the feasibility of using a clinical decision support(CDS) message to support consideration of SGLT2 inhibitor prescribing in patients with type 2 diabetes who recently had acute kidney injury.
- Conditions
- Type 2 Diabetes Mellitus, Acute Kidney Injury, Chronic Kidney Diseases, SGLT2 Inhibitor Use
- Trial name
- NCT07868666
- Testing
- Clinical Decision Support Message
- Volunteers
- 250 people
- Sponsor
- University of Minnesota
Remimazolam, Propofol
Remimazolam on the Incidence of Postoperative Acute Kidney Injury
We hypothesized that in patients undergoing elective hepatobiliary-pancreatic surgery, the group in which anesthesia is induced and maintained with remimazolam during surgery would maintain hemodynamic stability and reduce the…
- Conditions
- Remimazolam, Propofol, Acute Kidney Injury, Hemodynamic Stability
- Trial name
- NCT07674719
- Testing
- Remimazolam (Byfavo), propofol
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- Seoul National University Bundang Hospital
Acute Kidney Injury
Establish and Apply the Evaluation System of Ultrasonic Integrated Technology for Prevention and Treatment of Acute Kidney Injury
Establish an integrated evaluation system of ultrasound technology for the prognosis of acute kidney injury, and in order to achieve non-invasive, reliable early diagnosis "gold standard".
- Trial name
- NCT02347930
- Testing
- kidney ultrasound
- Where
- China
- Volunteers
- 196 people
- Sponsor
- RenJi Hospital
Acute Kidney Injury
Diagnostic Value of Urinary Indices in Differentiating Pre-renal and Renal Acute Kidney Injury
The study aims to evaluate the diagnostic value of urinary indices in differentiating pre-renal and renal acute kidney injury among critically ill patients.
- Trial name
- NCT02376712
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking Union Medical College Hospital
Acute Coronary Syndrome
Protective Effect of Early High Dose stATins On Cardiovascular and Renal Events in Acute Coronary Syndrome
Registration of all ACS patients (STEMI and NSTEMI) admitted to the cardiology ward and scheduled for early invasive strategy. The aim is to evaluate the protective effects of early (on admission) high-dose high-potency statin…
- Trial name
- PRATO-ACS (NCT04087200)
- Where
- Italy
- Volunteers
- 2,500 people
- Sponsor
- Centro Cardiopatici Toscani
Multiple Myeloma, Light Chain Nephropathy
Novel Treatments in Improving Renal Outcomes in Light Chain Cast Nephropathy
Objective 1: To test whether treatment with plasma exchange improves renal recovery in patients with light chain cast nephropathy Objective 2: To compare renal outcomes among patients treated with plasma exchange versus…
- Conditions
- Multiple Myeloma, Light Chain Nephropathy, Acute Kidney Injury
- Trial name
- NCT06483139
- Testing
- Plasma exchange, Daratumumab
- Where
- United States
- Volunteers
- 549 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Severe Burns, Acute Kidney Injury
Association of Continuous Renal Replacement Therapy With Mortality and Length of Stay in Critically Burned Patients
This retrospective observational study aims to investigate the clinical outcomes of critically ill burn patients who underwent continuous renal replacement therapy (CRRT).
- Conditions
- Severe Burns, Acute Kidney Injury, Critical Illness
- Trial name
- CRRT-BURN (NCT07195565)
- Where
- Turkey (Türkiye)
- Volunteers
- 238 people
- Sponsor
- Pinar Timur Tasci
Cardiorenal Syndrome, Heart Failure
Venous Ultrasound Guided Organ Decongestion in Patients Hospitalized with Acute Decompensated Heart Failure
The purpose of this study is to assess the feasibility, safety and effectiveness of VExUS guided organ decongestion compared to standard of care in patients hospitalized with acute decompensated heart failue (ADHF).
- Conditions
- Cardiorenal Syndrome, Heart Failure, Acute Kidney Injury, Acute Decompensated Heart Failure
- Trial name
- VExOUS-ADHF (NCT06714409)
- Testing
- VExUS guided decongestion
- Where
- Norway
- Volunteers
- 180 people
- Sponsor
- Oslo University Hospital
Living-Kidney Donors
Dietary Interventions During Living Kidney Donations
Monocentre, non-randomized, non-blinded, open-label interventional study to identification of relevant changes in molecular biology in proteome, phosphoproteome, lipidome, epigenome and transcriptome in pretransplant kidney…
- Trial name
- DILKID (NCT05709600)
- Testing
- Fasting mimicking diet, Ketogenic diet, Dietary restriction of sulfur containing amino acids
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Cologne
Cardiac Surgery
Intravenous Amino Acid Therapy for Kidney Protection in Cardiac Surgery.
To date, no pharmacological agents are proven efficacious in treating perioperative AKI. There is a strong biological rationale for the administration of amino acid in the management of patients at risk of AKI with increases in…
- Trial name
- PROTection (NCT03709264)
- Testing
- Amino Acids
- Where
- 22 sites in Croatia, Italy and 1 more
- Volunteers
- 3,511 people
- Sponsor
- Università Vita-Salute San Raffaele
Surgery--Complications, Perioperative/Postoperative Complications
Telemedicine Notifications With Machine Learning for Postoperative Care
The ODIN-Report study will be a randomized controlled trial of the effect of providing machine learning risk forecasts to providers caring for patients immediately after surgery on serious complications.
- Conditions
- Surgery--Complications, Perioperative/Postoperative Complications, Acute Kidney Injury, Hospital Mortality
- Trial name
- ODIN-Report (NCT03974828)
- Testing
- Anesthesia Control Tower Notification
- Sponsor
- Washington University School of Medicine
AKI - Acute Kidney Injury, Arrythmia
Tailored MgSO4 Supplementation to Reduce Complications in Pediatric Heart Surgery
Lay Summary This study tests two ways of measuring blood magnesium after heart surgery. Children who need heart surgery may have heart and kidney problems after surgery. The right amount of magnesium in blood reduces this risk.
- Conditions
- AKI - Acute Kidney Injury, Arrythmia, Congenital Heart Disease
- Trial name
- NCT06564376
- Testing
- total magnesium, ionized magnesium
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- West Virginia University
Glomerular Filtration Rate, Acute Kidney Injury
Pharmacokinetics of MP-3180 in Healthy Volunteers
The purpose of this study was to investigate the pharmacokinetics of MP-3180 (1 µmol/kg) compared to the pharmacokinetics of iohexol (5 mL of a 300 mg iodine (I)/mL solution) in healthy adult participants.
- Trial name
- Pilot 1A (NCT02098174)
- Testing
- MP-3180, Iohexol comparator
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- MediBeacon
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