Clinical trials: Renal Insufficiency,Chronic
Chronic Kidney Failure
Observational Study of Kibow Biotics in Chronic Kidney Failure Patients
A specifically formulated probiotic product comprised of defined and tested microbial strains may afford renoprotection in what has been generally called "Enteric DialysisTM".
- Trial name
- NCT01450657
- Testing
- Kibow Biotics/Renadyl
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Kibow Pharma
Kidney Failure, Chronic
Saving Residual Renal Function Among Haemodialysis Patients Receiving Irbesartan
Angiotensin II receptor blockers (ARB) are known to preserve kidney function among patients with kidney diseases and reduced renal function, but not among haemodialysis patients.
- Trial name
- SAFIR (NCT00791830)
- Testing
- Irbesartan
- Where
- 6 sites in Denmark
- Volunteers
- 82 people
- Sponsor
- University of Aarhus
End-stage Renal Disease, Hemodialysis
Does Moderate Physical Activity in Hemodialysis Patients Reduce Inflammation?
The purpose of this study is to observe a potential benefit of moderate physical activity by using bed mounted cycles during hemodialysis treatment sessions on inflammatory markers in the blood of patients with end-stage renal…
- Trial name
- NCT00893165
- Testing
- moderate physical activity
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Chronic Kidney Failure, Secondary Hyperparathyroidism
Paricalcitol Oral Therapy in Predialysis CKD Patients. The Greek Experience
The purpose of this study is to obtain data on the use of Zemplar (paricalcitol) capsules in real-life clinical practice in predialysis patients with chronic kidney disease (CKD) and secondary hyperparathyroidism.
- Trial name
- PROTECT (NCT01083186)
- Where
- 24 sites in Greece
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- AbbVie (prior sponsor, Abbott)
Chronic Kidney Diseases
Aerobic Exercise in Patients With CKD
Patients with chronic kidney disease (CKD), especially those who are on dialysis, have a high prevalence of cardiovascular mortality and among the risk factors; inflammation and oxidative stress stand out.
- Trial name
- NCT04375553
- Testing
- Aerobic exercise
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Universidade Federal Fluminense
Heart Failure With Preserved Ejection Fraction, End Stage Renal Disease on Dialysis
EMPAgliflozin in Heart Failure With PReserved Ejection Fraction and End Stage Renal Disease
The presence of CKD has been linked to the development of HFpEF. Currently, the treatment for HFpEF is limited. SGLT2i are one of the few drug classes that have proven efficacy in HFpEF in randomized controlled trials.
- Trial name
- EMPA-PRED (NCT06249945)
- Testing
- Empagliflozin 25 MG
- Where
- 2 sites in Taiwan
- Volunteers
- 150 people
- Sponsor
- National Taiwan University Hospital
End Stage Renal Disease (ESRD), Maintenance Hemodialysis
Impact of APP-assisted Patient Management on the Quality Control of Blood Purification Therapy
Many maintenance hemodialysis (MHD) patients develop negative outlooks due to their illnesses and complications, making their quality of life and prognosis a clinical concern.
- Trial name
- NCT07291154
- Testing
- APP-based management
- Where
- China
- Volunteers
- 392 people
- Sponsor
- Yunfeng Xia
Chronic Renal Failure, Kidney Transplantation
Fluid Intake in Kidney Failure
Patients with renal impairment are usually advised to increase their fluid intake. There is currently, however, no evidence supporting this recommendation.
- Trial name
- NCT00842322
- Testing
- high fluid intake, normal fluid intake
- Where
- Austria
- Volunteers
- 76 people
- Sponsor
- Medical University of Vienna
End Stage Renal Disease, End-Stage Kidney Disease
Shared Decision Making for Kidney Transplant Candidates to Plan for an Organ Offer Decision
The goal of this pilot randomized trial is to learn about shared decision making in kidney transplant candidates. The aim of this proposal is to evaluate the Donor Plan Donor Choice tool to promote high-quality Shared Decision…
- Conditions
- End Stage Renal Disease, End-Stage Kidney Disease, Kidney Transplantation, Esrd
- Trial name
- NCT05879302
- Testing
- Kidney Offer Shared Decision Making
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Hennepin Healthcare Research Institute
Chronic Kidney Diseases, Colon Polyp
Low-volume vs High-volume Polyethylene Glycol Based Bowel Preparation for Colonoscopy in People Receiving Hemodialysis
Current American Society for Gastrointestinal Endoscopy (ASGE) and European Society of Gastrointestinal Endoscopy (ESGE) guidelines recommend a split regimen of high-volume (4-liter polyethylene glycol-based preparation) or…
- Conditions
- Chronic Kidney Diseases, Colon Polyp, Dialysis; Complications, Colon Cancer
- Trial name
- PrepDial (NCT04709770)
- Testing
- 2-liters polyethylene glycol with citrate and simethicone, 4-liters polyethylene glycol with simethicone, Low-residue diet
- Volunteers
- 264 people
- Sponsor
- Alfredo Di Leo
Chronic Kidney Disease, End Stage Renal Disease
Risk of Chronic Kidney Disease Progression
While there are proven therapies that slow CKD progression, these therapies can at times be harmful and costly. The ability to accurately predict the risk of CKD progression to ESRD would be extremely valuable.
- Trial name
- NCT02654756
- Where
- United States
- Volunteers
- 623 people
- Sponsor
- Winthrop University Hospital
End-Stage Renal Disease
Pediatric Kidney Transplant Without Calcineurin Inhibitors
The purpose of this study is to see the effect of using drugs other than calcineurin inhibitors to improve the rate of kidney transplant failure. Kidney transplantation can help children with end-stage kidney disease.
- Trial name
- NCT00023231
- Testing
- Daclizumab, Methylprednisolone/prednisone, Mycophenolate mofetil
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
COVID-19, End Stage Renal Disease
The Danish Pre-HCQ COVID Dialysis Study
Hydroxychloroquine has been shown to inhibit replication of SARS-CoV-2 in vitro. The presented multicenter parallel-group open-label randomized clinical trial aims to investigate the efficacy of prophylactic hydroxychloroquine on…
- Trial name
- NCT05110651
- Testing
- Hydroxychloroquine
- Where
- 3 sites in Denmark
- Sponsor
- Nicholas Carlson
Kidney Failure, Chronic, Oxidative Stress
Effects of Royal Jelly Supplementation in Chronic Kidney Disease
The objective of this study is to evaluate the effects of royal jelly on inflammation and cellular senescence in patients with chronic kidney disease (CKD) on hemodialysis (HD).
- Conditions
- Kidney Failure, Chronic, Oxidative Stress, Hemodialysis
- Trial name
- NCT06438445
- Testing
- Real Jelly
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal Fluminense
Heart Failure, Renal Disease, Chronic
Outpatient Hypertonic Saline and Loop Diuretic Combination Therapy in Cardiorenal
Congestive heart failure (CHF) remains a major cause of morbidity, rehospitalization, and mortality worldwide, particularly among elderly and polymorbid patients.
- Trial name
- SALT-HF (NCT07596329)
- Testing
- Hypertonic sodium chloride 10%, Sodium Chloride 0.9%, Furosemide intravenous solution
- Volunteers
- 60 people
- Sponsor
- University of Monastir
CKD Stage 4, CKD Stage 5
The Effects of Application Intervention on the Physiological Indicators and Low Protein Diet Cognition Among the Patients With Chronic Kidney Disease
The effects of Application intervention on the physiological indicators and low protein diet cognition among the patients with chronic kidney disease
- Trial name
- NCT06083545
- Testing
- App
- Where
- Taiwan
- Volunteers
- 184 people
- Sponsor
- yi ting Hsu
Chronic Kidney Disease Stage 2, Radiographic Contrast Agent Nephropathy
N-Acetyl Cystein and Contrast Nephropathy
There are many controversies about the role of N-Acetyl Cystein in preventing of contrast nephropathy. These contradictory results may be due to different criteria for patients' selection, different end points, different type and…
- Trial name
- NCT01820195
- Testing
- Oral N-Acetyl Cystein, IV N-Acetyl Cystein
- Where
- Iran
- Volunteers
- 549 people
- Sponsor
- Imam Khomeini Hospital
End Stage Renal Disease on Dialysis
The Effect of Individualized Education Using the Teach-Back Method Treatment on Treatment Adherence and the Coping Skills
This study was planned to evaluate the effect of individual education given to adult patients with End Stage Renal Disease receiving hemodialysis treatment, using the Roy Adaptation Model-Based Teach Back Method under the…
- Trial name
- NCT05978479
- Testing
- Teach-Back Method
- Volunteers
- 64 people
- Sponsor
- Saglik Bilimleri Universitesi
Turner Syndrome, Renal Insufficiency, Chronic
Study to Define Optimal IGF-1 Monitoring in Children Treated With NutropinAq
The main purpose of this study is to establish an optimal monitoring regimen in NutropinAq treated children, using newly developed capillary blood spot IGF-1 measurement technology.
- Conditions
- Turner Syndrome, Renal Insufficiency, Chronic, Pituitary Diseases, Dwarfism
- Trial name
- OPTIMA (NCT00234533)
- Testing
- Somatropin (rDNA origin)
- Where
- 45 sites in Belgium, Czechia and 12 more
- Volunteers
- 251 people
- Sponsor
- Ipsen
Chronic Renal Failure, Anemia
Safety & Efficacy of EPO-018B for the Treatment of Anemia in Participants With ERSD Receiving Maintenance Hemodialysis
The purpose of this study is to evaluate the safety,efficacy, pharmacodynamics (PD), and pharmacokinetics (PK) of multiple intravenous doses of EPO-018B in participants with chronic kidney disease (CKD) who are on hemodialysis.
- Trial name
- NCT02366325
- Testing
- EPO-018B
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jiangsu Hansoh Pharmaceutical Co., Ltd.
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