Clinical trials: Renal Stone Disease
Kidney Calculi
Flexible Ureteroscopy for Large Renal Stones in Children
This prospective single-arm interventional study evaluated the efficacy and safety of flexible ureteroscopy for the treatment of large renal stones measuring 2 cm or more in pediatric patients.
- Trial name
- NCT07780409
- Testing
- Flexible Ureteroscopic Stone Disintegration
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Kidney Stones
Extracorporal Shockwave Lithotripsy Versus Retrograde Intrarenal Surgery for the Treatment of Kidney Stones
The purpose of this study is to compare two established modalities for the treatment of kidneystones: ESWL (extracorporal shockwave-lithotripsy) vs. URS (uretero-reno-scopy with stone-extraction).
- Trial name
- NCT01514032
- Testing
- Extracorporal shockwave lithotripsy, Retrograde intrarenal surgery
- Where
- Switzerland
- Volunteers
- 230 people
- Sponsor
- University of Zurich
Postoperative Pain, Kidney Calculi
Nephrostomy Tract Infiltration for Pain Control After PCNL
This prospective, randomized, controlled clinical trial aims to evaluate the effectiveness of nephrostomy tract local anesthetic infiltration for postoperative pain control in patients undergoing prone percutaneous…
- Trial name
- NCT07721571
- Testing
- Bupivacaine, Intravenous Tramadol and Paracetamol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hitit University
Kidney Stone
Impact of Acute Computed Tomography on Treatment Decisions and Time to Intervention in Renal Colic
This study intend to evaluate the use of acute computed tomography (CT) when acute renal colic, regarding treatment decisions, time to intervention and additional visits to the Emergency Department
- Trial name
- NCT06535711
- Testing
- Acute CT, Deferred CT
- Where
- Sweden
- Volunteers
- 612 people, healthy volunteers welcome
- Sponsor
- Region Skane
Renal Colic, Kidney Stone
Erector Spinae Plane Block for Uncomplicated Renal Colic
This research study is to determine how well the Erector Spinae Plane Block (ESPB) works for kidney stone pain and any possible side effects.
- Trial name
- NCT05625802
- Testing
- Erector Spinae Plane Block (ESPB), Ropivacaine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Michigan
Nephrolithotomy, Percutaneous, Kidney Calculi
Total Tubeless Percutaneous Nephrolithotomy Without a Ureteral Catheter
Total tubeless Percutaneous nephrolithotomy (PCNL) is a modified surgical method of PCNL surgery, that is, there is no indwelling nephrostomy tube and double-J tube during PCNL surgery.
- Trial name
- NCT05578807
- Testing
- without reverse ureteral catheter insertion
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of University of South China
Nephrolithiasis, Urinary Tract Infections
A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL])
When patients are going to have surgery to remove large kidney stones (percutaneous nephrolithotomy [PCNL]), it is not clear whether the patients benefit from a course of prophylactic preoperative oral antibiotics; currently both…
- Trial name
- NCT02384200
- Testing
- nitrofurantoin monohydrate/macrocrystalline capsules, ampicillin, gentamicin
- Where
- 8 sites in United States, Canada
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Kidney Calculi, Kidney Stones
VISOR Versus PCNL for Treatment of 2-4cm Renal Stones
The goal of this clinical trial is to learn if the Vortex Intelligence Stone Optimized Removal (VISOR) works safely and effectively to treat kidney stones that are 2 to 4 centimeters in size in kidney.
- Trial name
- NCT07159503
- Testing
- Vortex Intelligence Stone Optimized Removal, Percutaneous Nephrolithotomy (PCNL)
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Urinary Calculi
Silent Ureteral Stone: Impact on Renal Function and Kidney Anatomy
Ureteral stones may be silent in 5.3% of patients. The goal of this study was to prospectively evaluate the impact of a silent ureteral stone on renal function.
- Trial name
- NCT01884870
- Testing
- Surgical Treatment
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- University of Sao Paulo
Kidney Stones, Calcium Oxalate Kidney Stones
Phosphate & Kidney Stones
Kidney stones are common and often come back. One reason may be that some people with calcium stones have low phosphate levels in the blood and lose too much phosphate through the kidneys.
- Conditions
- Kidney Stones, Calcium Oxalate Kidney Stones, Hypophosphatemia
- Trial name
- NCT07903961
- Testing
- Neutral Phosphate
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Chicago
Kidney Stone
Research on Early Warning and Diagnosis & Treatment Pathway for Micro Kidney Stones
Exploring abnormal metabolism in kidney stone patients and developing drugs for kidney stone treatment and their mechanisms of action.
- Trial name
- NCT07350369
- Testing
- Detect the levels of metabolites in blood and urine
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Kidney Stones
Can a Spot Urine Replace or Improve 24 Hour Urine Collections in Kidney Stone Patients
This study will sought to determine if limited urine collections can provide similar or more informative data than standard 24-hour urine collections used to evaluate kidney stone formers.
- Trial name
- NCT01420354
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- University of British Columbia
Kidney Stone
Impact of the SGLT2 Inhibitor Empagliflozin on Urinary Supersaturations in Kidney Stone Formers
The aim of this study is to test the effect of a new drug on the composition of the urine in kidney stone patients. This new drug (Jardiance®, substance: empagliflozin) is currently approved in Switzerland for the treatment of…
- Trial name
- SWEETSTONE (NCT04911660)
- Testing
- Empagliflozin 25 MG
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Renal Stone
Comparison of Different Analgesia Drug Regimens for Pain Control During ESWL for Renal Stones
We want to compare the effect of lignocaine 2 % gel, Naproxen sodium and their combination on the pain control during extracorporial shock wave lithotripsy for renal stones.
- Trial name
- NCT02786446
- Testing
- Lidocaine gel,, Naproxen Sodium, Lidocaine gel and Naproxen Sodium
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Shifa International Hospital
Prostatic Hyperplasia, Kidney Calculi
Aqueduct Irrigation System Clinical Protocol: Medical Device Investigational Plan
A. Synopsis 1. This protocol comes to direct the experiment to be performed on the Aqueduct Automatic Continuous Irrigation system. 2.
- Conditions
- Prostatic Hyperplasia, Kidney Calculi, Bladder Tumors
- Trial name
- NCT02496442
- Testing
- Aqueduct
- Volunteers
- 30 people
- Sponsor
- Flowmed
Chronic Kidney Disease, Nephrolithiasis
Kidney Sodium Functional Imaging
The corticomedullary gradient is largely responsible for developing the gradients that are needed to concentrate urine (more solutes and less water).
- Conditions
- Chronic Kidney Disease, Nephrolithiasis, ADPKD
- Trial name
- NCT05014178
- Testing
- Sodium-23 MRI
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Urolithiasis, Kidney Stone
A Retrospective, Multi-center Real-world Study of Steerable Ureteroscopic Renal Evacuation (SURE) Procedure With the CVAC® System
This is a retrospective, multi-center collaboration to assess real-world outcomes of a novel steerable aspiration system, the CVAC® System ("CVAC"), and flexible and navigable suction ureteral access sheath (FANS) for the…
- Conditions
- Urolithiasis, Kidney Stone, Kidney Stones
- Trial name
- REASON (NCT07225933)
- Testing
- CVAC® SYSTEM, FLEXIBLE AND NAVIGATIONAL URETERAL ACCESS SHEATH (FANS) IN FLEXIBLE URETEROSCOPY (FURS)
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Calyxo, Inc.
Kidney Stone
CT-Ultrasound Fusion in Guiding PCNL Puncture
Kidney stone is a common urological disease. Percutaneous nephrolithotomy (PCNL) is an important method for the treatment of kidney stones.
- Trial name
- NCT04645472
- Testing
- CT-Ultrasound
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Zhenyu Wu
Nephrolithiasis, Lithotripsy, Laser
Comparison Between Ureterorenoscopy With Lithotripsy Alone Versus Combination With Hydrogel for Kidney Stone Removal
The incidence of kidney stones (urolithiasis) has surged in both developing and developed countries, affecting approximately 15% of the global population.
- Conditions
- Nephrolithiasis, Lithotripsy, Laser, Ureteroscopy
- Trial name
- NCT06469736
- Testing
- Standard of Care Ureterorenoscopy, Standard of Care Ureterorenoscopy with MediNiK
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Technical University of Munich
Ureteral Calculus, Ureterolithiasis
Silodosin Versus Tamsulosin for Treatment of Ureteral Stones
Ureteral calculi, commonly known as kidney stones, are a frequent cause of Emergency Department (ED) visits. These stones can get caught in the ureter (the tube connecting the kidney to the bladder) and cause symptoms including…
- Conditions
- Ureteral Calculus, Ureterolithiasis, Ureteral Stone
- Trial name
- NCT02369744
- Testing
- Silodosin, Tamsulosin
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Albert Einstein Healthcare Network