Clinical trials: Renal Stone Disease
Kidney Calculi
Mini-PCNL Versus Standard-PCNL For The Management of 20-40 mm Size Kidney Stones
Percutaneous nephrolithotomy (PCNL) has been considered as the first-line choice for the management of >20mm kidney stones. The traditional nephrostomy tract of PNL was dilated to 24-30F, which is referred to as "Standard-PCNL".
- Trial name
- NCT02635048
- Testing
- Mini Percutaneous Nephrolithotomy, Percutaneous Nephrolithotomy
- Where
- China
- Volunteers
- 1,980 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Postoperative Pain Management, Urolithiasis
The Use of Intranasal Ketoralac for Pain Management (Sprix)
Despite an overall reduction in the perioperative complication rate, post operative pain management after ureteroscopic removal of stones (URS) remains a major factor delaying discharge of patients.
- Trial name
- NCT01736358
- Testing
- Intranasal Ketoralac
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Montefiore Medical Center
Kidney Stone, Ureteroscopy
Retrograde Intrarenal Stone Surgery - A Method of Treating the ESWL Resistant Kidney Stone
Is it possible to decrease the intrarenal pressure in the kidney during endoscopic management of kidney stone by topical administration of drugs? In order to secure fewer complications in ureteroscopic operations the…
- Trial name
- NCT00323843
- Testing
- Isoproterenol
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Fredericia Hosptial
Kidney Calculi
A Dietary Source of Potassium Citrate to Resolve Hypocitraturia and Aciduria in Patients With Kidney Stones
Patients with nephrolithiasis and evidence of hypocitraturia or aciduria who would otherwise be started on potassium citrate, can achieve similar urine alkalization with 500-1000 mL of daily low calorie orange juice consumption.
- Trial name
- NCT03984409
- Testing
- Kroger low calorie orange juice beverage
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- Indiana University
Kidney Stones, Urolithiasis
ILY Robotic System vs Manual Flexible Ureteroscopy for Kidney Stone Treatment
The goal of this clinical trial is to compare the efficacy, ergonomics, and safety of robotic versus manual flexible ureteroscopy (fURS) for kidney stone treatment in adult patients undergoing laser lithotripsy.
- Trial name
- iFURS (NCT06996587)
- Testing
- Robotic-Assisted Flexible Ureteroscopy, Manual Flexible Ureteroscopy
- Where
- Lebanon
- Volunteers
- 152 people
- Sponsor
- Albert El Hajj
Perioperative/Postoperative Complications, Kidney Stone
Investigate the Renal Movement by Single Lung Ventilation in Patients Administered RIRS for Kidney Stones.
In patients undergoing RIRS for kidney stone, we aim to show the effect of single lung ventilation with a double lumen tube on operative (operation scope duration, perforation, hemorrhage, etc.
- Trial name
- NCT03060837
- Testing
- Preoperative Parameters, Peroperative Parameters, Postoperative Parameters
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Kidney Stones
Visceral Pain From the Upper Urinary Tract - a Trial on the Effect of Morphine and Oxycodone in Patients Undergoing PCNL
The purpose of this study is to investigate the effect of oxynorm versus morphine after operation for kidney stone (PCNL). In addition the relationship between pain symptoms and referred sensory and trophic changes will be…
- Trial name
- NCT00784472
- Testing
- oxycodone, morphine
- Where
- Denmark
- Volunteers
- 55 people
- Sponsor
- Katja venborg Pedersen
Kidney Stones, Nephrolithiasis
Empiric Versus Selective Prevention Strategies for Kidney Stone Disease
The aims of this study are to 1) Conduct a randomized clinical trial of selective versus empiric diet plus pharmacologic therapy in high-risk stone formers and 2) Determine adverse effects from, and adherence to selective and…
- Trial name
- NCT05365477
- Testing
- Empiric Therapy: Diet, Empiric Therapy: Drug, Selective Therapy: Diet
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Vanderbilt University Medical Center
Kidney Calculi
Effect of Anesthesia Type on Surgeon Workload During Endoscopic Kidney Stone Surgery
This prospective observational study aims to evaluate the association between anesthesia type and surgeon-perceived workload and surgical ergonomics in adult patients undergoing flexible ureteroscopy and retrograde intrarenal…
- Trial name
- RIRS-ERG (NCT07763600)
- Testing
- General Anesthesia (GA), Spinal Anesthesia (SA)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Malatya Governor Research Hospital
Renal Stone
Effect of Preoperative Silodosin on Feasibility of Ureteral Access Sheath Insertion
The ureteral access sheath (UAS) is an ancillary device widely used by urologists to facilitate fast, repeatable, and safe access to ureters and collecting systems; improve visibility; reduce the risk of infection by reducing…
- Trial name
- NCT05833386
- Testing
- Ureteral access sheath placement during flexible ureteroscope for renal stones
- Where
- Egypt
- Volunteers
- 2,000 people
- Sponsor
- Al-Azhar University
Renal Calculi
Using Retrograde Intrarenal Surgery for Managing Staghorn Renal Stones.
This prospective, randomized study is comparing the safety and efficacy of using two types of ureteral access sheaths in managing staghorn renal stones by retrograde intrarenal surgery.
- Trial name
- NCT07342361
- Testing
- Retrograde intrarenal surgery
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Helwan University
Periodontal Diseases, Nephrolithiasis
The Association Between Nephrolithiasis and Periodontal Status
Dental calculus is a calcified deposits firmly attached to teeth and implants surfaces. Dental calculus is strongly associated with periodontitis and considered to have indirect role in the pathogenesis of periodontal diseases.
- Trial name
- NCT03102086
- Testing
- Scaling
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Rambam Health Care Campus
Acute Kidney Injury, Renal Calculi
Evaluation of Renal Damage After PCNL and ESWL Using Novel RNA Based Biomarkers
The study evaluate the damage effect of ESWL and PCNL on kidney tissue by measuring non-coding lnc-RNA profile in urine before and after ESWL and PCNL procedures
- Conditions
- Acute Kidney Injury, Renal Calculi, Percutaneous Nephrolithotomy, Extracorporeal Shockwave Lithotripsy
- Trial name
- NCT05077007
- Testing
- Percutaneous nephrolithotomy, Extracorporeal Shock Wave Lithotripsy
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Nephrolithiasis, Urolithiasis
Comparison of Flexible & Navigable Suction Ureteral Access Sheath vs. Antegrade Suction in Retrograde Flexible Ureteroscopy for Lower Calyceal Stones
This randomized controlled trial aims to compare the efficacy and safety of two suction techniques during retrograde flexible ureteroscopy (FURS) for lower calyceal renal stones measuring 1.5-2 cm.
- Conditions
- Nephrolithiasis, Urolithiasis, Endourology
- Trial name
- NCT06889051
- Testing
- Flexible & Navigable Suction Ureteral Access Sheath (FANS), Antegrade Suction via Percutaneous Nephrostomy
- Volunteers
- 120 people
- Sponsor
- Benha University
Surgery-Complications, Nephrolithiasis Staghorn Calculus
Comparison of Total Tubeless Mini-PCNL Versus Tubeless Mini-PCNL
Limited literature has focused on the use of totally tubeless mini-percutaneous nephrolithotomy (Mini-PCNL) for the treatment of large renal stones.
- Conditions
- Surgery-Complications, Nephrolithiasis Staghorn Calculus, Safety Issues
- Trial name
- NCT06288022
- Testing
- total tubeless mini-PCNL, tubeless mini-PCNL
- Where
- Thailand
- Volunteers
- 130 people
- Sponsor
- Mahidol University
Kidney Stones, Surgical Blood Loss
Combined Intravenous and Irrigation Tranexamic Acid During Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy is a minimally invasive surgical procedure used to remove large kidney stones. Although it is an effective treatment, bleeding during and after the procedure remains one of the main concerns and may…
- Conditions
- Kidney Stones, Surgical Blood Loss, Percutaneous Nephrolithotomy
- Trial name
- NCT07582341
- Testing
- Tranexamic acid, Normal Saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Benha University
Renal Stone
Basic Hemodynamic Monitoring Reliability During Percutaneous Nephrolithotomy.
This prospective pre and post-quasi-descriptive single group interventional study will be done at urology and nephrology center -Mansoura University during the year 2019, for a 3-month duration, starting 1-2-2019 till 1-4-2019…
- Trial name
- NCT03828175
- Testing
- spinal anesthesia monitoring
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Kidney Stone
Neutrophil Extracellular Traps (NET's) in Prevalent Kidney Stone
Neutrophils are first responders to any kind of threat the body faces: infection, severe trauma, cancer, surgery... They produce the cytokines, induct oxidative stress and de-granulate toxic proteins to kill pathogens.
- Trial name
- NCT06412822
- Testing
- Blood sampling, Urine sampling
- Where
- Belgium
- Volunteers
- 500 people
- Sponsor
- Brugmann University Hospital
Kidney Stones, Renal Calculi
Database and Registry for Renal Diverticulum
Historically, percutaneous treatment of stone-bearing caliceal diverticula has resulted in the best success rates when examining factors such as symptom relief and stone-free rates (Jones, et al, 1991).
- Conditions
- Kidney Stones, Renal Calculi, Tic
- Trial name
- NCT00169715
- Testing
- Percutaneous Caliceal Diverticuli
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Indiana Kidney Stone Institute
Kidney Calculi
Efficacy of Potassium Sodium Hydrogen Citrate Therapy on Renal Stone Recurrence and/or Residual Fragments After Shockwave Lithotripsy and Percutaneous Nephrolithotomy in Calcium Oxalate Urolithiasis
Extracorporeal shock wave lithotripsy (ESWL) and Percutaneous nephrolithotomy (PCNL) become the therapy of choice for renal stone.
- Trial name
- NCT01329042
- Testing
- Potassium-sodium citrate
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ouiheng International Healthcare Co., Ltd