Clinical trials: Renal Stone Disease
Kidney Stone, Benign Prostatic Hyperplasia
Utilization of a Web-Based Application to Improve Patient Health Literacy and Reduce Clinic Visit Times in Holmium Laser Enucleation of the Prostate (HoLEP) Procedures and Kidney Stone Surgery
The investigator and research team plan to investigate whether patients who receive access to WellPrept website will report greater confidence and understanding of their medical condition, have shorter clinic visit times, and…
- Trial name
- NCT07580391
- Testing
- WellPrept, Standard Care
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Kidney Calculi
Influence of Anesthesia Methods on Surgical Outcomes and Renal Function
Patients who underwent retrograde intrarenal surgery (RIRS) were randomly allocated to general anesthesia (GA) or spinal anesthesia (SA) groups.
- Trial name
- NCT03957109
- Testing
- general anesthesia
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Seoul National University Hospital
Stone, Kidney
Silodosin in Management of Lower Ureteral Stones
This research aims to study the effectiveness of silodosin in the management of lower ureter stones larger than 6 mm in diameter in terms of affected ureter (right or left), the size of the stone, the degree of hydronephrosis…
- Trial name
- NCT06381206
- Testing
- Silodosin
- Where
- Syria
- Volunteers
- 100 people
- Sponsor
- Syrian Private University
Renal Stone, Percutaneous
Erector Spinae Versus Paravertebral in Pediatric PCNL
To compare the efficacy of ultrasound-guided erector spinae plane block versus ultrasound-guided paravertebral block in pediatric patients undergoing percutaneous nephrolithotomy
- Conditions
- Renal Stone, Percutaneous, Nephrolithotomy
- Trial name
- NCT05589649
- Testing
- Erector spinae plane block, Paravertebral block
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Assiut University
Enteric Hyperoxaluria, Primary Hyperoxaluria
Study of ALLN-177 in Patients Aged 12 Years or Older With Enteric or Primary Hyperoxaluria and Hyperoxalemia
Evaluate the efficacy and safety of ALLN-177 in reducing plasma and urinary oxalate levels in adult and pediatric patients with enteric hyperoxaluria and hyperoxalemia or primary hyperoxaluria
- Conditions
- Enteric Hyperoxaluria, Primary Hyperoxaluria, Hyperoxalemia
- Trial name
- NCT03391804
- Testing
- ALLN-177
- Where
- 9 sites in United States, Germany and 1 more
- Volunteers
- 15 people
- Sponsor
- Allena Pharmaceuticals
Kidney Calculi
Comparing Super Pulse Fiber Thulium Laser and Holmium Laser for Ureteral Stone Fragmentation During Ureteroscopy
The goal of this prospective, multicenter, randomized controlled trial is to objectively evaluate the clinical efficacy and safety differences between superpulse thulium fiber laser (sTFL) and holmium:YAG laser (Ho:YAG) in…
- Trial name
- NCT06667557
- Testing
- Superpulse Thulium Fiber Laser (sTFL) Treatment, Holmium:YAG Laser (Ho:YAG) Treatment
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Nephrolithiasis, Urinary Tract Infection (UTI)
Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2
This study will be a multi-institutional randomized clinical trial of a short course of pre-operative antibiotic prophylaxis in addition to perioperative antibiotics prior to undergoing percutaneous nephrolithotomy.
- Conditions
- Nephrolithiasis, Urinary Tract Infection (UTI), Sepsis
- Trial name
- PNLABXPART2 (NCT02829060)
- Testing
- Nitrofurantoin 100 MG, 7d, Gentamicin, 5mg/kg, Ampicillin 2g
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- University of California, San Diego
Kidney Stones
A Trial of Pyridoxamine to Lower Urine Oxalate in Subjects With Stone Disease or Hyperoxaluria
To determine whether pyridoxamine can decrease oxalate excretion in subjects who have normal oxalate excretion (but who have had kidney stones), and in subjects who have primary hyperoxaluria.
- Trial name
- NCT00490113
- Testing
- Pyridoxamine
- Sponsor
- University of Kansas Medical Center
Ureteral Diseases
Daily Versus Twice Per Day Tamsulosin for Ureteral Stent Symptoms
A single-center prospective, randomized study to assess two different dosing regimens (0.4 mg QD vs. 0.4 mg BID) of tamsulosin for ureteral stent-related discomfort will be completed.
- Trial name
- NCT03799120
- Testing
- Tamsulosin BID
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Gundersen Lutheran Medical Foundation
Kidney Stone, Calculi, Renal
Our Stone Fixation Technique to Improve Efficiency and Results of Peumatic Lithotripsy in Suction Mini-PCNL.
Prospective study to assist safty and efficieny of our technique of using peumatic lithotripsy with suction mini-pcnl.
- Trial name
- NCT07328659
- Testing
- Peumatic lithotripsy in mini-pcnl
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Yasser Gamil Elnagar
Kidney Cancer, Ureteral Cancer
Postoperative Telerounding: A Multi-Center Prospective Randomized Assessment of Patient Outcomes and Satisfaction.
Telerounding is the use of wireless remote video-confrencing to assess hospitalized patients. Physicians thus rely on all ususal data collected during bedside rounds with the exeption of a direct physical exam.
- Conditions
- Kidney Cancer, Ureteral Cancer, Prostate Cancer, Nephrolithiasis
- Trial name
- NCT00263107
- Testing
- telerounding versus bedside rounding
- Where
- 3 sites in United States
- Volunteers
- 270 people
- Sponsor
- University of California, Davis
Healthy, Enteric Hyperoxaluria
Safety and Tolerability of FB-001 in Healthy Adult Volunteers and Adult Subjects With Enteric Hyperoxaluria
This Phase 1, first-in-human, randomized, double-blinded, placebo controlled study is evaluating FB-001 in healthy volunteers (Part 1) and participants diagnosed with enteric hyperoxaluria (Part 2).
- Trial name
- NCT05650112
- Testing
- FB-001
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Federation Bio Inc.
Kidney Calculi, Ureter Calculi
Naftopidil 75mg for Improving Clearance of Urinary Stones
The purpose of this study is to evaluate Efficacy and Safety of oral intake of Naftopidil 75mg once daily for the improving clearance of ureteral or renal stones.
- Trial name
- NCT02011737
- Testing
- naftopidil 75mg
- Where
- South Korea
- Volunteers
- 130 people
- Sponsor
- Samsung Medical Center
Kidney Disease
A Prospective Comparison Between Ureteral Stent and Nephrostomy Tube for an Urgent Drainage of Obstructed Kidney
Kidney obstruction might be caused by a stone in the urinary tract. In case of accompanying fever or renal failure, an urgent drainage might be needed. This can be done either by placing an ureteral stent or a nephrotomy tube.
- Trial name
- JJVsPCN08 (NCT00739284)
- Testing
- nephrostomy tube and ureteral stent
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Rabin Medical Center
Urolithiasis, Kidney Stone
Comparing Efficacy and Complication Between Prone Versus Prone-Flexed Position for Percutaneous Nephrolithotomy (PCNL)
Comparing Efficacy and Complication Between Prone Versus Prone-Flexed Position For Percutaneous Nephrolithotomy (PCNL)
- Conditions
- Urolithiasis, Kidney Stone, Complication
- Trial name
- NCT06624306
- Testing
- Prone PNL, Prone-flexed PNL
- Where
- Egypt
- Volunteers
- 85 people
- Sponsor
- Fayoum University Hospital
Nephrolithiasis, Kidney Stone
HoYAG vs TFL in miniPCNL With ClearPetra
Mini percutaneous nephrolithotripsy is the treatment of choice for kidney stones over 2cm. This procedure commonly uses laser energy for breaking the stones, and among possible laser platforms, Hoyag and thulium fiber laser are…
- Trial name
- NCT07087977
- Testing
- HoYAG laser, TFL laser platform
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Kansas Medical Center
Renal Stone
Tamsulosin as Adjunctive Therapy After Extracorporeal Shock Wave Lithotripsy for Renal Stones
Urolithiasis is a common health problem worldwide affecting approximately 10% of the population at some stage in their lives. The aim of this study is to evaluate the efficacy of adjuvant treatment with tamsulosin for improving…
- Trial name
- NCT04819828
- Testing
- Extracorporeal shock wave lithotripsy, Diclofenac, Tamsulosin
- Volunteers
- 60 people
- Sponsor
- Hospital Regional de Alta Especialidad del Bajio
Urolithiasis, Kidney Calculi
Safety and Efficacy of Traditional Versus Flexible and Navigable Suction Sheath in Retrograde Intra-Renal Stone Surgery
This study compares two techniques used during RIRS for the treatment of kidney stones measuring up to 20 mm. During RIRS, surgeons often use a device called a UAS to help pass instruments into the urinary system and to assist…
- Conditions
- Urolithiasis, Kidney Calculi, Nephrolithiasis
- Trial name
- NCT07286071
- Testing
- Retrograde intrarenal surgery using a ureteral access sheath with suction, Retrograde intrarenal surgery using a traditional ureteral access sheath
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Ain Shams University
Stones, Kidney
Optimal Drainage After Flexible Ureterorenoscopy; Prospective Assessment of Perioperative Outcomes and Health-Related Quality of Life Through a Randomized Controlled Trial
Flexible ureterorenoscopy (FURS) is now recommended for the treatment of kidney stones smaller than 20 mm, as an alternative to extracorporeal shock wave lithotripsy (ESWL) and in combination with percutanous nephrolithotomy…
- Trial name
- NCT04643145
- Testing
- Flexible ureteroscopy for renal calculi less than 20 mm
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Mansoura University
Nephrolithiasis
RIRS With Flex Suction Sheath vs. PCNL for 2-3 cm Renal Stones
This is a multicenter, randomized controlled trial comparing retrograde intrarenal surgery (RIRS) using a tip-flexible suction access sheath with standard percutaneous nephrolithotomy (PCNL) for the treatment of 2-3 cm unilateral…
- Trial name
- NCT07058402
- Testing
- Retrograde Intrarenal Surgery (RIRS) with Tip-Flexible Suction Access Sheath, Standard Percutaneous Nephrolithotomy (PCNL)
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Changhai Hospital