Clinical trials: Renal Stones
Obesity, Nephrolithiasis
Nephrolithiasis and Bariatric Surgery
Test the hypothesis that the new bariatric surgical procedures (BSP) increase stone risk, and will result in an increased incidence and prevalence of stone disease; the purpose is to determine if BSP patients require special…
- Trial name
- NCT00169793
- Testing
- evaluation of kidney stone risk after bariatric surgery, Evaluate risk of kidney stones after bariatric surgery
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Indiana Kidney Stone Institute
Kidney Stones
Laser Versus Ultrasonic Lithotripsy in Percutaneous Nephrolithotomy for Staghorn Stones
This study will be conducted to compare the results of Laser and ultrasonic lithotripsy in disintegration of staghorn stones during percutaneous nephrolithotomy.
- Trial name
- NCT01922414
- Testing
- Laser, Ultrasonic
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Primary Hyperoxaluria Type 1, PH1
Study of YOLT-203 in Children and Adults With Primary Hyperoxaluria Type 1 (PH1)
This study will be conducted to evaluate the efficacy and safety of YOLT-203 in children and adults with Primary Hyperoxaluria Type 1.
- Trial name
- NCT07587021
- Testing
- YOLT-203
- Where
- 4 sites in United States
- Volunteers
- 36 people
- Sponsor
- YolTech Therapeutics Co., Ltd
Kidney Stone, Kidney Calculi
Holmium Vs Trilogy Kidney Stones GUY's 1-2
The desire to reduce complications related to percutaneous access and morbidity related to tract size has led researchers to evaluate PCNL using smaller-caliber instruments. In this context, mini-PCNL has emerged.
- Conditions
- Kidney Stone, Kidney Calculi, Kidney Diseases
- Trial name
- TriHolmium (NCT04559321)
- Testing
- Fragmentation of calculi with 100 W Holmium laser or LithoClast Trilogy EMS and 1.5 mm x 440 mm probe, according to randomization.
- Where
- Mexico
- Volunteers
- 116 people
- Sponsor
- Hospital Regional de Alta Especialidad del Bajio
Nephrolithiasis
Thulium vs. Hol:YAG Laser
This is a randomized prospective study to compare stone free rates and operative efficiency of two laser systems used during retrograde intrarenal surgery for kidney stone disease: 1.
- Trial name
- NCT05808257
- Testing
- Thulium Fibre Laser, Holmium:Yttrium-Aluminum-Garnet
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Renal Stone, Pediatric
Flexible Ureteroscopy Versus Mini- Percutaneous Nephrolithotomy in Management of Pediatric Renal Stones Less Than 2 cm
This single-center, prospective, two-arm randomized controlled trial included 58 patients younger than 18 years who were allocated 1:1 to Mini-PCNL or FURS between June 2023 and December 2024.
- Trial name
- NCT07870200
- Testing
- Group A :Flexible ureteroscope group, Group B : Mini perc group
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Elsayed Abdelhalim Elsayed
Percutaneous Nephrolithotomy (PCNL), Surgical Positioning
Hemodynamic Effects of Surgical Position in Prone vs. Supine Percutaneous Nephrolithotomy
This prospective, randomized controlled study evaluates the hemodynamic effects of prone and supine positions during percutaneous nephrolithotomy (PNL) for large kidney stones.
- Conditions
- Percutaneous Nephrolithotomy (PCNL), Surgical Positioning, Prone Position, Supine Position
- Trial name
- NCT07138872
- Testing
- Prone Position Percutaneous Nephrolithotomy, Supine Position Percutaneous Nephrolithotomy (Galdakao-modified Valdivia)
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Primary Hyperoxaluria, Cystinuria
Health-related Quality of Life in Rare Kidney Stone
Assessment of Health-related Quality of Life in Rare Kidney Stone Formers in the Rare Kidney Stone Consortium
- Conditions
- Primary Hyperoxaluria, Cystinuria, Adenine Phosphoribosyl Transferase Deficiency, Dent Disease
- Trial name
- NCT02124395
- Testing
- Health-related Quality of Life in Rare Kidney Stone Questionnaire
- Where
- 3 sites in United States, Iceland
- Volunteers
- 365 people
- Sponsor
- NYU Langone Health
Nephrolithiasis
Effect of Antihistamines on Ureteral Stent-Related Symptoms
This is a prospective, double-blind, randomized, open-label, single-center trial of up to 78 participants who are adult patients (aged 18-80 years) and are undergoing unilateral retrograde ureteroscopy with planned ureteral stent…
- Trial name
- NCT04726345
- Testing
- Fexofenadine Hcl 180Mg Tab
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Columbia University
Renal Stone
Comparison Between External Oblique Intercostal Block and Erector Spinae Plane Block in PCNL
The aim of the study is to compare the post-operative analgesic effect of USG unilateral External oblique intercostal (EOI) block with Erector spinae plane block (ESPB) for after percutaneous Nephrolithotomy with a hypothesis…
- Trial name
- NCT06131151
- Testing
- External Oblique Intercostal Block, Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Assiut University
Renal Injury, Kidney Injury
Efficacy and Safety of Renalof® in the Removal of Calculi Smaller Than 10 mm Located in the Reno-Ureteral Tract
Given the high recurrence of urolithiasis in patients, the search for less aggressive and preventive treatments is increasingly necessary.
- Conditions
- Renal Injury, Kidney Injury, Kidney Calculi, Ureteral Obstruction
- Trial name
- NCT04695951
- Testing
- Renalof
- Where
- Nicaragua
- Volunteers
- 155 people
- Sponsor
- Catalysis SL
Nephrolithiasis
The Use of Belladonna and Opium Suppository in the Treatment of Postoperative Stent Pain
The purpose of this study is to determine if preemptive B\&O suppository placement will decrease post-operative pain in patients undergoing ureteral stent placement.
- Trial name
- B&O (NCT03332056)
- Testing
- Belladonna and Opium
- Volunteers
- 71 people
- Sponsor
- University of Washington
Renal Stones, Pediatric Renal Stones
Retrograde Intrarenal Surgery for Renal Stones in Pediatrics: A Prospective Analysis of Feasibility and Outcomes.
it is an interventional single arm study for treating pediatric renal stones≤2cm by FURS and Holmium laser fragmentation.pediatric groups is benig compared for stone free rate, complication rate , success rate.
- Trial name
- RIRS pediatric (NCT07089394)
- Testing
- flexible urs
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al-Azhar University
Kidney Stones
Pilot Study of Patient Navigation for Kidney Stone Patients After ED Visits
Patients who visit the emergency department for kidney stones are sometimes referred to urology for follow-up care but never complete that visit.
- Trial name
- NCT07322172
- Testing
- Patient Navigation
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of California, San Francisco
Kidney Calculi
Effects of Potassium Citrate in Urine of Children With Elevated Calcium in Urine and Kidney Stones
High amounts of calcium in the urine (hypercalciuria) can cause development of kidney stones in children. Treatment for these children includes plenty of fluids, a low-salt diet and medications such as potassium citrate.
- Trial name
- NCT00120731
- Testing
- Potassium Citrate, Acetazolamide, Diet low in oxalate and purines
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Urolithiasis
Renal Stone Treatment Global Registry
This is an international prospective data registry to assess the treatment outcomes and complications of different treatment approaches for different surgical treatment of urolithiasis.
- Trial name
- NCT05297331
- Where
- 3 sites in Hong Kong
- Volunteers
- 3,000 people
- Sponsor
- Chinese University of Hong Kong
Pediatric Kidney Disease
Shockwave Lithotripsy (SWL) Versus SWL and Oral Dissolution Therapy (ODT) For Paediatrics Radiolucent Renal Stone
To conduct a RCT comparing SWL versus combined ODT and SWL as non-invasive methods for management of paediatrics radiolucent renal stone.
- Trial name
- NCT05896345
- Testing
- SWL, SWL and ODT
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Mansoura University
Renal Stone
Erector Spinae Plane Block for Analgesia During ESWL
this study aims to compare between efficacy of erector spinae plane block and conventional multimodal analgesia in Extracorporeal shock wave lithotripsy
- Trial name
- NCT07067996
- Testing
- erector spinae plane block, Nalbuphine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Renal Stone Disease, Renal Stones
Flexible Ureteroscopy With Novel Flexible Ureteral Access Sheath Versus Mini-Percutaneous Nephrolithotomy for Treatment of 2-3cm Lower Calyceal Renal Stones
The aim of the study is to compare the efficacy, safety, and patient outcomes of flexible ureteroscopy with a novel flexible ureteral access sheath and mini-percutaneous nephrolithotomy in the treatment of 2-3 cm lower calyceal…
- Conditions
- Renal Stone Disease, Renal Stones, Flexible Ureteroscopy, Mini Percutaneous Nephrolithotomy
- Trial name
- NCT07904676
- Testing
- Flexible Ureteroscopy with Novel Flexible Ureteral Access Sheath, Mini-Percutaneous Nephrolithotomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Kidney Calculi, Postoperative Pain
Is it Really Necessary to Insert a Nephrostomy Tube or Double J Stent in Percutaneous Nephrolithotomy?
In this study, investigators aimed to compare the postoperative pain status and comfort situations depending on instruments used in the percutaneous nephrolithotomy operation
- Trial name
- NCT06062849
- Testing
- nephrostomy tube, double J stent, totally tubless
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bursa City Hospital