Clinical trials: Renal Transplant Patient
Kidney Transplant, Immunology
Protective Immunity Project 02
Influenza (Flu) vaccine is recommended for kidney transplant patients who are at least 6 months post-transplant. The influenza vaccine stimulates the immune system to builds protective antibodies against the flu virus.
- Conditions
- Kidney Transplant, Immunology, Immunosuppression
- Trial name
- PIP-02 (NCT00833651)
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Emory University
Cancer
Antithymocyte Globulin, Clofarabine, and Rituximab in Treating Patients After an Unsuccessful Stem Cell Transplant
RATIONALE: Antithymocyte globulin, clofarabine, and rituximab may stop the patient's immune system from rejecting the donor's stem cells when they do not exactly match the patient's blood.
- Trial name
- NCT00617929
- Testing
- anti-thymocyte globulin, rituximab, clofarabine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Kidney Disease, Liver Transplantation
Evaluation of Kidney Disease in Liver Transplant Recipients
A non-invasive urinary test that detects kidney injuries in liver transplant (LT) candidates would be useful for monitoring of kidney damage.
- Trial name
- NCT00585429
- Where
- United States
- Sponsor
- University of Wisconsin, Madison
Multiple Myeloma
WT1 Vaccine Treatment of Patients With Multiple Myeloma After Autologous Stem Cell Transplantation
The purpose of this trial is to assess the immune response after vaccination with a peptide vaccine called galinpepimut-S (or GPS) in a type of blood cancer called multiple myeloma.
- Trial name
- NCT01827137
- Testing
- Galinpepimut-S, GM-CSF, Montanide
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Sellas Life Sciences Group
Renal Failure, Hyponatremia
Effect of Midodrine and Albumine in the Prevention of Complications in Cirrhotic Patients Awaiting Liver Transplantation
The aim of this study is to evaluate the effect of prolonged administration of albumin and midodrine on the prevention of complications (renal failure, sepsis, hemorrhage, hepatic encephalopathy and hyponatremia) in patients with…
- Conditions
- Renal Failure, Hyponatremia, Sepsis, Hepatic Encephalopathy
- Trial name
- MACHT (NCT00839358)
- Testing
- albumin, Midodrine
- Where
- Spain
- Volunteers
- 199 people
- Sponsor
- Hospital Clinic of Barcelona
Cutaneous Squamous Cell Carcinoma, Skin Cancer
Cosibelimab for CSCC in Patients With Kidney Transplant or Hematologic Malignancy
This is study is to evaluate the safety and efficacy of cosibelimab in special populations with advanced cutaneous squamous cell carcinoma (CSCC).
- Trial name
- NCT07426484
- Testing
- Cosibelimab, Prednisone, Sirolimus
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Dana-Farber Cancer Institute
Kidney Diseases
Enteric-coated Mycophenolate Sodium (EC-MPS) With Reduced-dose Tacrolimus Versus EC-MPS With Standard-dose Tacrolimus in Stable Kidney Transplant Recipients
This study introduces a new optimization immunosuppressive regimen associating tacrolimus at a reduced dose and enteric-coated mycophenolate sodium at an increased dose in order to slow down renal function worsening and to…
- Trial name
- OLYMPE (NCT00284934)
- Testing
- Enteric-coated mycophenolate sodium (EC-MPS), Tacrolimus, Corticosteroids
- Where
- Switzerland
- Volunteers
- 94 people
- Sponsor
- Novartis
Kidney Transplant
Long-term Follow-up of Spare the Nephron (STN) Patients
Allograft nephropathy is the most common cause of allograft failure following kidney transplantation. Among putative etiologies, cumulative exposure to calcineurin inhibitors may be one of the important progression factors.
- Trial name
- STN (NCT01126333)
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Maryland, Baltimore
Kidney Transplant; Complications
TruGraf Utilization in High IPV Levels
Intra-patient variability (IPV) in tacrolimus is associated with premature graft loss. The rate of acute rejection episodes is higher in these patients, and acute rejection impacts negatively on graft survival.
- Trial name
- NCT04280276
- Testing
- TruGraf test
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Maryland, Baltimore
End Stage Renal Disease
Rituximab Desensitization Therapy for Patients on the Waiting List for Kidney Transplant
This is a study of patients who have a high risk of kidney rejection before kidney transplant. The hypothesis is that treatment with a medication called rituximab will make it possible for them to receive a kidney transplant from…
- Trial name
- NCT00167791
- Testing
- rituximab
- Where
- United States
- Sponsor
- University of Wisconsin, Madison
Cancer
Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain
This is a phase III, randomized, double-blind, placebo-controlled, multicenter study of the clinical response to fentanyl sublingual spray as a treatment for breakthrough cancer pain.
- Trial name
- NCT00538850
- Testing
- Fentanyl sublingual spray
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- INSYS Therapeutics Inc
Disorder of Transplanted Kidney
Plasma Marine n-3 Polyunsaturated Fatty Acids and Patient and Graft Survival
This study will evaluate the association between n-3 polyunsaturated fatty acids and patient and graft survival. The association between other fatty acids and mortality and graft loss endpoints will also be evaluated.
- Trial name
- NCT02017990
- Where
- Norway
- Volunteers
- 2,002 people
- Sponsor
- Oslo University Hospital
End-stage Renal Disease, Dialysis
Economic Evaluation of an Education Platform for Patients With End-stage Renal Disease
1600 patients with severe, end stage renal disease or post transplant will be randomised 1:1:1 to either standard therapeutic education; or education using a specific app; or the enhanced interactive app using feedback messages.
- Conditions
- End-stage Renal Disease, Dialysis, Kidney Transplantation
- Trial name
- PIC-R (NCT03090828)
- Testing
- app-based therapeutic education, enhanced app-based therapeutic education
- Volunteers
- 1,600 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Kidney Transplantation, Treatment Refusal
Survey of Adherence to Immunosuppression and Other Medications in Kidney Transplant Patients
Goal: To define the causes and issues associated with nonadherence in our population Hypothesis: There is a difference in the rates and patterns of adherence to transplant medications versus other medications also taken by…
- Conditions
- Kidney Transplantation, Treatment Refusal, Patient Compliance
- Trial name
- NCT00433134
- Testing
- Adherence
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- State University of New York - Downstate Medical Center
Preoperative KIDNEY FAILURE, CHRONIC, Postoperative KIDNEY FAILURE, ACUTE
NGAL Predictive Value of Acute Kidney Failure After Cardiac Surgery in Patients With Preoperative Chronic Kidney Failure
Primary endpoint: To evaluate predictive value of plasmatic levels of Neutrophil Gelatinase Associated Lipocalin (NGAL) to reveal acute kidney failure after cardiac surgery in patients with preoperative chronic kidney failure…
- Conditions
- Preoperative KIDNEY FAILURE, CHRONIC, Postoperative KIDNEY FAILURE, ACUTE, Cardiac Surgical Procedures
- Trial name
- NGAL-CKF (NCT01227122)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hopital Jean Minjoz
High Blood Pressure
ALLOGRAFT, A Study to Evaluate the Renal Protective Effects of Losartan (0954-222)(COMPLETED)
To demonstrate that losartan (+ conventional therapy) compared to placebo (+ conventional therapy) will reduce the number of RT patients who experience histological lesions of chronic allograft nephropathy
- Trial name
- NCT00140907
- Testing
- losartan potassium
- Volunteers
- 367 people
- Sponsor
- Organon and Co
Disorder Related to Renal Transplantation, Renal Transplant Rejection
Testing Immunosuppression Threshold in Renal Allografts To Extend eGFR
This study evaluates the addition of "Kidney Solid Organ Rejection Test" (kSORT), in the clinical follow-up of renal transplant recipients, compared to clinical standard surveillance in the first two years after kidney…
- Conditions
- Disorder Related to Renal Transplantation, Renal Transplant Rejection, Acute Graft Rejection
- Trial name
- TITRATE (NCT02581436)
- Testing
- kSORT assay based follow-up, Standard follow-up
- Where
- Mexico
- Volunteers
- 70 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Food Insecurity, Kidney Transplant
Vouchers for Improving Transplant Access to Lifestyle Nutrition - Kidney Transplant
This study evaluates the effect of a six-month fruit and vegetable voucher program on satisfaction, dietary quality, and health outcomes among pediatric and young adult kidney transplant recipients experiencing food insecurity.
- Trial name
- VITAL-KT (NCT06953336)
- Testing
- Fruit and Vegetable Voucher Support Program
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of California, San Francisco
Viruria
CMX001 in Post-transplant Patients With BK Virus Viruria
This was a randomized, double-blind, multiple-dose placebo-controlled study of oral brincidofovir (BCV) in hematopoietic stem cell transplant and renal transplant recipients with BK virus viruria.
- Trial name
- NCT00793598
- Testing
- Brincidofovir
- Where
- 15 sites in United States
- Volunteers
- 29 people
- Sponsor
- Jazz Pharmaceuticals
Chronic Renal Disease
Once-a-day Immunosuppression(CISECON_a_day)
The objective of this study is to assess the efficacy and safety and Immunosuppressant Therapy Barrier Scale (ITBS) of once daily immunosuppressant maintenance therapy in patients who had kidney transplantations earlier.
- Trial name
- CISECON (NCT01964014)
- Testing
- advagrf
- Where
- 7 sites in South Korea
- Volunteers
- 160 people
- Sponsor
- Ajou University School of Medicine