Clinical trials: Renin Angiotensin Aldosterone System
Obesity, Cardiovascular Diseases
PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis
Obese individuals have a higher prevalence of nocturnal hypertension and non-dipping blood pressure (BP). These conditions are associated with an increased risk of cardiovascular (CV) events and death.
- Conditions
- Obesity, Cardiovascular Diseases, Hypertension, Nocturnal Blood Pressure
- Trial name
- PRECISION-BP (NCT04971720)
- Testing
- Sacubitril-Valsartan 49 Mg-51 Mg Oral Tablet, Valsartan 80 mg Oral Tablet
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Renin-Angiotensin Aldosterone System (RAS)
Human Intestinal Amino Acid Absorption and the Role of a Local RAS
This study is to find out what role a local intestinal RAS (renin angiotensin system) plays in the context of amino acid absorption in the human intestinal tract and how this RAS and thus the amino acid absorption is influenced…
- Trial name
- NCT04524494
- Testing
- biopsy of intestinal tissue, blood draw, urine collection
- Where
- 2 sites in Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital Basel