Clinical trials: Reproduction
Reproductive Performance Following Ovarian Transplantation
Transplantation of Frozen Thawed Ovarian Tissue High Reproductive Performance
Design: prospective cohort study. Setting: Tertiary university-affiliated ART and oncology centers. Patients: 20 cancer survivors who underwent ovarian transplantation of frozen-thawed ovarian tissue, with the aim to conceive.
- Trial name
- NCT02659592
- Testing
- transplantation of ovarian tissue
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Human Microbiota, PreTerm Birth
The Reproductive Microbiome & Perinatal Health Outcomes
Pregnant African American women between 18 and 45 years of age will be enrolled at 20 weeks of gestation or less. Biological specimens (vaginal swabs, rectal swab) will be collected at enrollment, 23-24 weeks, at 28-29 weeks, and…
- Conditions
- Human Microbiota, PreTerm Birth, Human Gastrointestinal Microbiota, Metabolomics
- Trial name
- NCT02948192
- Testing
- Survey, Sample collection
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Pregnancy Prevention, Sexual Behavior
Project Legacy Impact Evaluation Study
This study will design and rigorously evaluate the efficacy of Project Legacy, a five week positive youth development intervention to decrease sexual risk for unintended pregnancies and STIs among youth experiencing homelessness…
- Conditions
- Pregnancy Prevention, Sexual Behavior, Contraception Behavior, Sexually Transmitted Diseases
- Trial name
- NCT03366636
- Testing
- Project Legacy
- Where
- 12 sites in United States
- Volunteers
- 571 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
COVID-19
Retrospective Study of COVID-19 on Reproductive Function
This multi-center, retrospective cohort study aimed to determine which factors are associated with ongoing pregnancy rates in infertile patients received ART treatments during the current outbreak of COVID-19 infection.Couples…
- Trial name
- NCT05685966
- Testing
- no intervention
- Where
- 3 sites in China
- Volunteers
- 400 people
- Sponsor
- Jinling Hospital, China
Assisted Reproductive Technology
Family Foundations for Individuals Pregnant Via ART
The purpose of this study is to help expectant mothers build a coparenting bond and improve communication with a support person (co-caregiver).
- Trial name
- NCT06770972
- Testing
- Family Foundations
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Cedars-Sinai Medical Center
Fertility Preservation, Cancer Remission
Long-term Evaluation of Fertility Preservation Options in Women in Cancer Remission or Haematological Pathology
Cancer treatments, despite their increasing effectiveness, carry a significant risk of gamete toxicity. Women of reproductive age are commonly offered fertility preservation (FP) before starting their treatment.
- Conditions
- Fertility Preservation, Cancer Remission, Reproductive Outcomes, Reproductive Health
- Trial name
- FERT-ISSUES (NCT07312058)
- Where
- France
- Volunteers
- 102 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Polycystic Ovary Syndrome
A Study to Explore Correlation Between Symptoms and Signs of Polycystic Ovarian Syndrome (PCOS) and Risk of Over-response to Ovarian Stimulation
This is a Phase IV, prospective, observational, single arm, multicenter trial to identify the population at high risk of overstimulation associated with signs and symptoms of PCOS and examines the utility of 12.5 international…
- Trial name
- ARTIST (NCT02607293)
- Testing
- Gonal-f®, Long GnRH agonist, GnRH antagonist
- Where
- Germany
- Volunteers
- 1,064 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Sexual and Reproductive Health, Menopausal and Postmenopausal Women
THE EFFECT OF SEXUAL COUNSELING BASED ON THE EXPLISSIT MODEL ON SEXUAL FUNCTION, MARITAL ADJUSTMENT, AND QUALITY OF SEXUAL LIFE IN POSTMENOPAUSAL WOMEN
Sexual health is not merely about sexual dysfunction, but a complex, diverse, and multifaceted natural process encompassing a wide range of aspects of human life, extending from childhood to old age.
- Trial name
- NCT07559916
- Testing
- Group receiving sexual counseling based on the EX PLISSIT model.
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Nurses' Occupational Health, Mental Health
Gansu Nurses' Health Cohort Study
This study aims to understand the health status, work stress, and occupational exposure in the work environment among nurses in Gansu Province, China.
- Conditions
- Nurses' Occupational Health, Mental Health, Chronic Diseases, Occupational Exposure
- Trial name
- NCT07645911
- Testing
- Questionnaire Investigation
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- LanZhou University
Infertility
Efficacy and Safety Study of a Single Injection of SCH 900962 Versus Daily recFSH Injections in Women Undergoing Controlled Ovarian Stimulation (Study P06029)
The purpose of this study is to show that a single injection of SCH 900962/MK-8962 is non-inferior to daily injections of recombinant follicle-stimulating hormone (recFSH) during the first week of ovarian stimulation in terms of…
- Trial name
- PURSUE (NCT01144416)
- Testing
- SCH 900962 / Corifollitropin alfa / Org 36286, RecFSH / follitropin beta
- Volunteers
- 1,424 people
- Sponsor
- Organon and Co
Trauma-related Mental Health Symptoms
Adaptation and Examination of a Trauma-informed Intervention for Pregnant Veterans
The current proposal aims to refine and examine an intervention called Calm Moms. Calm Moms is a web-based treatment program designed to reduce anxiety, stress, and low mood symptoms among pregnant Veterans with a history of…
- Trial name
- NCT06906185
- Testing
- Calm Moms-V, Care As Usual
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Infertility
DNA Damage and Subfertility in Males - Impact on ART Outcome
A obvational prospective cohort study of men undergoing IUI, IVF and ICSI treatment in Denmark. The aim is to asses the impact of sperm DNA damage, measured as DNA fragmentation index (DFI), on reproductive outcomes after…
- Trial name
- ReproDNA (NCT04160208)
- Where
- Denmark
- Volunteers
- 1,350 people
- Sponsor
- Regionshospitalet Viborg, Skive
HIV (Human Immunodeficiency Virus)
Evaluation of the Effectiveness of the HPV Education Program Applied to Women
This study aimed to evaluate the effectiveness of an educational program conducted by nurses on Human Papilloma Virus and its effects on women's health in women of reproductive age.
- Trial name
- NCT07468487
- Testing
- Reproductive health education program
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Okan University
Platinum-Resistant Fallopian Tube Carcinoma, Platinum-Resistant Ovarian Carcinoma
MUC1-Activated T Cells for the Treatment of Relapsed and Resistant Ovarian Cancer
This phase I trial tests the safety, side effects, best dose of MUC1-activated T cells in treating patients with ovarian cancer that has come back after a period of improvement (relapsed) or that remains despite treatment…
- Conditions
- Platinum-Resistant Fallopian Tube Carcinoma, Platinum-Resistant Ovarian Carcinoma, Platinum-Resistant Primary Peritoneal Carcinoma, Recurrent Fallopian Tube Carcinoma
- Trial name
- NCT06483048
- Testing
- Autologous MUC1-activated T-cells, Bendamustine, Biospecimen Collection
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Mayo Clinic
Reproductive Issues, Subfertility
A Novel Integrative Non-invasive Embryo Selection Approach for IVF Based on MK-RS Analysis
During assisted reproductive technology treatment, embryo selection is an important process that may affect the clinical pregnancy rate.
- Conditions
- Reproductive Issues, Subfertility, IVF
- Trial name
- NCT05896709
- Testing
- MK-RS
- Where
- Hong Kong
- Volunteers
- 176 people
- Sponsor
- Chinese University of Hong Kong
Spontaneous Abortions, Infertility
Molecular Associations With Reproductive Failure
The overall hypothesis to be tested is: women with the molecular phenotype of highly skewed X chromosome inactivation are at increased risk of spontaneous abortion.
- Trial name
- NCT00298116
- Where
- United States
- Volunteers
- 475 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Infertility, Female, Genital Tuberculoses, Female
The Prevalence and Reproductive Outcome of Infertile Women With Genital Tuberculosis
Female genital tuberculosis infection (FGTB) is an important cause of female infertility in TB-endemic areas. The pregnancy rate of assisted reproductive treatment (ART) in the infertile women with FGTB is still unsatisfied even…
- Trial name
- TB-PRIME (NCT05311423)
- Testing
- QuantiFERON-TB test & endometrial pathology & endometrial tissue GeneXpert Ultra
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Huashan Hospital
IVF Outcomes, Stress Levels
Virtual Reality Use in Assisted Reproductive Technology
The study will examine the effect of exposure to virtual reality on stress levels and pregnancy rates, in infertile women undergoing in vitro fertilization embryo transfer
- Trial name
- NCT04394962
- Testing
- Virtual reality
- Where
- Canada
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Dr cliff Librach
Bipolar Disorder
Reproductive Function in Women With Bipolar Disorder
Many studies have shown that patients with bipolar disorder are prone to reproductive dysfunction, including polycystic ovary syndrome, hyperprolactinemia, and amenorrhea.
- Trial name
- NCT05307848
- Testing
- No intervention
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Central South University
Adenomyosis, in Vitro Fertilization
Cohort Profile：The Shandong Adenomyosis Cohort of Population Undergoing Reproductive Technology (SAart)
Previous studies have shown that compared with infertile women without adenomyosis, the clinical pregnancy rate, live birth rate and continuous pregnancy rate of women with adenomyosis significantly reduce, and the abortion rate…
- Trial name
- NCT06604091
- Testing
- Treatment protocol
- Where
- China
- Volunteers
- 2,241 people
- Sponsor
- The Second Hospital of Shandong University
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