Clinical trials: Reproduction
Contraception, Sexually Transmitted Diseases
Contraceptive Awareness and Reproductive Education
The purpose of this study is to increase the initiation and continuation of highly effective contraceptive use while incarcerated and upon release, as well as decrease unsafe sexual activity.
- Conditions
- Contraception, Sexually Transmitted Diseases, Pregnancy
- Trial name
- CARE (NCT01132950)
- Testing
- Motivational Interviewing, Didactic Educational Counseling
- Where
- 2 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Memorial Hospital of Rhode Island
Iron, Cerebral Blood Flow
16 Weeks' Dietary Supplementation With Iron and Iron + Vitamin C on Cerebral Blood Flow and Energy Expenditure in Women of Reproductive Age
Iron deficiency is the most prevalent nutritional deficiency worldwide with one in four estimated to be affected by iron deficiency anaemia.
- Conditions
- Iron, Cerebral Blood Flow, Energy Metabolism, Cognitive Function
- Trial name
- NCT04477018
- Testing
- Iron bis-glycinate chelate and vitamin C, Iron bis-glycinate chelate
- Where
- United Kingdom
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Contraception, Contraceptive Behavior
Patient-Centered Support for Contraceptive Decision-Making
The investigators have designed a tablet-based decision support tool to help women learn more about their birth control options and support them in choosing a method they are happy with.
- Trial name
- NCT02078713
- Testing
- Contraceptive Decision Support Tool
- Where
- 4 sites in United States
- Volunteers
- 786 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Infertility Assisted Reproductive Technology, Ovarian Aging
Epigenetic Clock to Predict Ovarian Aging and Live Birth in ART
Epigenetic clocks based on DNA methylation estimate biological age and are associated with age-related conditions, but they have not been validated for female fertility.
- Trial name
- ARTCLOCK (NCT07875140)
- Testing
- Peripheral blood sampling for epigenetic age estimation
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Early Pregnancy
Influence of Social and Environmental Factors on Women's Reproductive Function in a Maya Community of Guatemala
This study will explore the influence of social and environmental factors, such as stress, nutrition, health status, etc., on women's reproductive function.
- Trial name
- NCT00340782
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Contraceptive Usage
Disparities in Emergency Contraceptive Metabolism Dictate Efficacy
The purpose of this study is to learn more about why some people are at greater risk for oral emergency contraceptive failure while others are not.
- Trial name
- NCT05674513
- Testing
- Ulipristal acetate
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Mindfulness, Sexual Health
Mindfulness-Based Education on Sexual/Reproductive Health Stigma and Self-Esteem in Female University Students
This study was conducted to determine the effect of a mindfulness-based education program on mindfulness level, reproductive and sexual health stigma, and self-esteem among young women.
- Conditions
- Mindfulness, Sexual Health, Social Stigma, Self Esteem
- Trial name
- NCT07383090
- Testing
- Mindfulness-Based Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- EDA OZYON ETLI
Male Reproductive Problem
The Effects of Cannabis on Male Reproductive Functions
The purpose of this study is to understand the direct effects of cannabis on male reproductive functions. The investigators plan to conduct a double-blind, placebo-controlled clinical trial to examine both the chronic and acute…
- Trial name
- NCT06755346
- Testing
- Cannabis plant (THC 20mg), Cannabis (0%/ THC / 0% CBD), Cannabis plant (THC 40mg)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kanako Hayashi
Healthy, Deficiency Disease
Effects of Dietary Carbohydrate and Fat on Hormones
This study will try to determine if intake of dietary fats or carbohydrates influences the tendency to gain weight or accumulate body fat.
- Trial name
- NCT00016848
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Breast Cancer
Clinical and Biological Study of Early-onset Breast Cancer and the Influence of the Reproductive Cycle on the Aggressiveness of the Disease
The incidence of breast cancer is increasing, particularly among young women. Cancers in young women are associated with a poor prognosis. The causes remain poorly understood.
- Trial name
- ARTEMIS (NCT07601152)
- Testing
- No Intervention: Observational Cohort
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Institut Cancerologie de l'Ouest
Hypogonadotropic Hypogonadism
Kisspeptin Administration Subcutaneously to Patients With IHH
The goal of this study is to see whether kisspeptin, a naturally occurring hormone, can stimulate the release of other reproductive hormones in men and women with idiopathic hypogonadotropic hypogonadism (IHH).
- Trial name
- NCT05896293
- Testing
- kisspeptin 112-121, leuprolide acetate
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Stephanie B. Seminara, MD
HIV, Reproductive Health
Disability and HIV: Vulnerability of People With Disabilities to HIV Infection in Sub-Saharan Africa
According to the recent World Report on Disability, around 15% of the world population lives with a disability and 80% of people with disabilities (PWD) live in developing countries.
- Conditions
- HIV, Reproductive Health, Disability
- Trial name
- HandiVIH (NCT02192658)
- Where
- Cameroon
- Volunteers
- 1,610 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Infertility, Ovulation Induction
A Phase II Study to Assess the Efficacy and Safety of Luveris® (Lutropin Alfa) in Mid Follicular Phase for Controlled Ovarian Stimulation (COS) in Advanced Reproductive Age
Ovarian reserve is related to chronological age; 35 years of age is the accepted threshold for significant decline in assisted reproductive technologies (ART) success with scarce follicular recruitment and poor oocyte retrieval.
- Trial name
- NCT01079949
- Testing
- r-hLH + r-hFSH, r-hFSH, Recombinant Human Choriogonadotropin (r-hCG)
- Where
- Spain
- Volunteers
- 93 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Pregnancy in Adolescence, Counseling
Reducing Adolescent Pregnancy
This multi-site study is employing a brief contraception counseling intervention in the Emergency Department (ED) to shed light on factors that affect decision making as well as barriers and facilitators to conception initiation…
- Conditions
- Pregnancy in Adolescence, Counseling, Contraception Behavior
- Trial name
- NCT04120376
- Testing
- Contraception Counseling
- Where
- 2 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
ICSI, IVF
Dual Trigger VS HCG Trigger for Final Oocyte Maturation in Normal Responders
To compare the embryological and reproductive outcomes of dual trigger versus conventional hCG trigger for final oocyte maturation in normal responder patients undergoing ICSI cycles.
- Conditions
- ICSI, IVF, Normal Responders, Infertility Assisted Reproductive Technology
- Trial name
- DT-HCG-IVF (NCT07861399)
- Testing
- Dual trigger (human chorionic gonadotropin plus GnRH-agonist), hCG trigger
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Contraception, Pregnancy Related
Project for Reproductive Equity Through Volunteers and Entrepreneurship, Networks and Technology
The PREVENT Project is a multifaceted, adolescent friendly, culturally competent program aimed to address the issues surrounding unplanned pregnancies and lack of access and uptake of contraceptive services among adolescent…
- Conditions
- Contraception, Pregnancy Related, Reproductive Behavior
- Trial name
- PREVENT (NCT03995043)
- Testing
- Education, Personal Support, Access to contraception
- Where
- Canada
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Dr. Karen Yeates
HIV Infection, Sexual and Reproductive Health
PrEPared to Choose (PtC) is an Implementation Study of the Delivery of Cabotegravir Long-acting, an Injectable Pre-exposure Prophylaxis (PrEP) Option for HIV Prevention. Injectable PrEP Will be Offered Alongside Oral and Vaginal Ring PrEP From Within a Real-world Context in Cape Town, South Africa.
The goal of this clinical trial is to offer adolescents and young people in Cape Town, South Africa different HIV pre-exposure prophylaxis (PrEP) products and describe how they use these products over an 18-month period.
- Trial name
- PtC (NCT06807736)
- Testing
- Cabotegravir long-acting, Tenofovir emtricitabine, Dapivirine containing vaginal ring
- Where
- South Africa
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Desmond Tutu HIV Foundation
Primary Ciliary Dyskinesia (PCD)
A Qualitative Study Investigating the Lived Experiences and Impact of Reproductive Issues in Adults With Primary Ciliary Dyskinesia
Study involving undertaking research interviews with adults who have primary ciliary dyskinesia in the UK about their views and experiences of fertility, pregnancy and parenthood
- Trial name
- NCT07357558
- Testing
- Interview only
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Female Sexual Dysfunction (FSD), Sexuality and Reproductive Issues
Developing a Clinical Practice Guideline With The Delphi Technique for Evaluation and Counseling of Women's Sexual Health
Type of Research The research will be conducted prospectively and methodologically. The Delphi Technique, one of the qualitative research methods, will be used.
- Trial name
- NCT06880900
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Clinical Trial, Phase I
Study in Healthy Young Women to Investigate the Pharmacodynamics, Pharmacokinetics and Safety of Vilaprisan
This is a study in healthy women of reproductive age to investigate the pharmacodynamics (mainly ovarian activity), pharmacokinetics and safety of vilaprisan after daily oral administration of 4 different doses over 84 days…
- Trial name
- NCT02262663
- Testing
- Vilaprisan (BAY1002670)
- Where
- 2 sites in Germany
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bayer