Clinical trials: Reproductive Effects
Contraceptive Usage, Diffuse Noxious Inhibitory Control
Effects of Oral Contraceptives on DNIC in Non-painful Healthy Women
The purpose of this study is tu assess the influence of oral contraceptives (OC) on diffuse noxious inhibitory control (DNIC) in healthy women, tested during high, low endogenous estrogens sessions and ovulatory period.
- Trial name
- NCT04365426
- Testing
- Mechanical stimulus, Thermal (cold) stimulus, Oral contraceptive (OC)
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Vina del Mar
Low Ovarian Reserve
The Effect of Growth Hormone in Assisted Reproductive Technology Clinical Outcome of Poor Responder
Assisted reproduction treatment in patients with low ovarian reserve is a big difficult clinical problem. Growth hormone (GH) is crucial in the development of follicles since preantral follicle to ovulation and can promote…
- Trial name
- NCT03027843
- Testing
- Growth Hormone
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment
Couples Therapy to Enhance Intimacy Between Patients With Advanced or Recurrent Prostate Cancer and Their Partners
RATIONALE: A couples therapy program may enhance intimacy and reduce psychological distress in patients with prostate cancer and in their partners.
- Conditions
- Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment, Sexual Dysfunction, Sexuality and Reproductive Issues
- Trial name
- NCT00483678
- Testing
- counseling intervention, questionnaire administration, psychosocial assessment and care
- Where
- 2 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Reproductive System Disorder, Urinary Incontinence
The Effect of Polycystic Ovary Syndrome on Pelvic Floor Structure and Function
Polycystic Ovarian Syndrome (PCOS) is the most common endocrinological disorder in women of reproductive age, and its prevalence is reported to be 6-21% in women aged 15-49 (1).
- Conditions
- Reproductive System Disorder, Urinary Incontinence, Urogenital Disease, Polycystic Ovary Syndrome
- Trial name
- NCT04398186
- Testing
- Anogenital distance measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Giresun University
Infertility, Female
Effects of Pentoxifylline and Vitamin E on Pregnancy Rate in Infertile Women Treated by ICSI:
Our findings will provide preliminary clinical evidence to suggest the new experimental treatment approaches, toward female factor infertility treatment with pentoxyfylline.
- Trial name
- NCT03476564
- Testing
- pentoxifylline, Vit E
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Benha University
Contraceptive Usage, Coagulation
How DHEA Supplements Affect Coagulation in Women Using Birth Control Pills
A randomized study is to learn more about how a supplement called DHEA (dehydroepiandrosterone) affects clotting factors in women taking combined oral contraceptive pills.
- Trial name
- COC+DHEA (NCT03418363)
- Testing
- DHEA Oral Capsule
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
PCOS
L-carnitine and Metformin in Obese PCOS Women.
L-carnitine and plus metformin in clomiphene-resistant obese PCOS women, reproductive and metabolic effect: a randomized clinical trial
- Trial name
- NCT03108963
- Testing
- L-carnitine and Metformin
- Where
- Egypt
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Zagazig University
The Focus is to Investigate Effect of an Educational Video on Fecundity Knowledge Among Young Adults
Young Adults' Fecundity Knowledge and Fertility Intentions and Reproductive Behavior
This RCT investigates the impact of an educational video on fecundity knowledge among young adults. The video discusses several risk factors associated with fecundity, such as age and smoking.
- Trial name
- NCT06631950
- Testing
- Educational intervention
- Where
- 2 sites in Denmark, Norway
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Infertility in Women Undergoing Assisted Reproductive Treatment, Infertility
Gamified Healthy Lifestyle Training in Women Undergoing Assisted Reproductive Treatment
Objective: A prospective randomized controlled trial with a pretest-posttest design was planned to evaluate the effects of a gamified healthy lifestyle behaviors training intervention using the D6 model, to be administered to…
- Conditions
- Infertility in Women Undergoing Assisted Reproductive Treatment, Infertility, Assisted Reproductive Technology, Health Lifestyle Behaviors
- Trial name
- NCT07460661
- Testing
- Gamified Healthy Lifestyle Education+Digital Healthy Lifestyle Education Booklet, Digital Healthy Lifestyle Education Booklet
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Marmara University
Female Reproductive System Disorder
Effect of Modifications of Nutritional Intake Upon Reproductive Hormones in Normal Women
Undernutrition has a known and well recognized negative impact on reproductive hormones, and ultimately fertility. In contrast, much less is known regarding the potential effects of overnutrition on the same hormones.
- Trial name
- Polynut (NCT02233283)
- Testing
- Clamp, Hypercaloric diet, Basal
- Where
- Switzerland
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Menstrual Disorder, Premature Ovarian Failure
The Effect of HPV Vaccine on Menstrual Cycle in Women of Reproductive Age
Cervical cancer is one of the most common cancer in women, making it the fourth largest cause of female cancer mortality worldwide.
- Trial name
- NCT05838157
- Testing
- prophylactic HPV vaccine(bivalent HPV、quadrivalent HPV、9-valent HPV)
- Where
- 2 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Sexual Health, Reproductive Health
The Effect of Escape Room Game on Reproductive Health Knowledge and Gender Equality Perception
This study aims to evaluate the impact of an "escape room" educational game on university students' knowledge of sexual/reproductive health and their perceptions of gender equality.
- Conditions
- Sexual Health, Reproductive Health, Gender Equality, Health Education
- Trial name
- NCT07346313
- Testing
- Escape Room Game on Reproductive Health and Gender Equality, Standard Theoretical Education
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Endometriosis, Uterine Fibroids
A Trial of SHR7280 in Healthy Subjects
The study is being conducted to evaluate the effect of high-fat meal on pharmacokinetics of SHR7280 after oral administration and the effect of SHR7280 on QT interval at low and high doses in healthy Chinese volunteers.
- Conditions
- Endometriosis, Uterine Fibroids, Assisted Reproduction
- Trial name
- NCT06969664
- Testing
- SHR7280 Tablet
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Polycystic Ovary Syndrome, Obesity
Two Different Dietary Interventions for Girls With Polycystic Ovary Syndrome
This study was conducted to evaluate the efficacy of the MEtabolic Syndrome REduction in NAvarra (RESMENA) diet versus a control diet based on American Heart Association (AHA) recommendations for the treatment of PCOS in…
- Conditions
- Polycystic Ovary Syndrome, Obesity, Androgen; Hypersecretion, Diet, Healthy
- Trial name
- NCT05768724
- Testing
- intervention diet, control diet
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gazi University
Amenorrhea, Dysmenorrhea
Reproductive Effects of Pesticide, PCB and Mercury Exposure in Laotian Immigrants
This project is examining the reproductive effects of exposure to certain compounds that are suspected to act on the endocrine system, e.g. they may act like or interfere with hormones such as estrogen.
- Conditions
- Amenorrhea, Dysmenorrhea, Oligomenorrhea, Anovulation
- Trial name
- NCT00011388
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Sterility, Infertility
Myo-Inositol- Based Co-treatment in Women With PCOS Undergoing Assisted Reproductive Technology
This is a prospective comparative randomized controlled study investigating the effect of Myo-Inositol-based co-treatment on oocyte quality measures in women with PCOS.
- Trial name
- NCT03177122
- Testing
- Myo-inositol
- Where
- Lebanon
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Contraception, Estrogen Deficiency
Effect of Oestrogen on Musculoskeletal Outcomes
This cross-sectional comparison and prospective cohort design study will investigate differences in calcium metabolism, biochemical markers of bone and reproductive health, musculoskeletal health, and iron status between women…
- Conditions
- Contraception, Estrogen Deficiency, Estrogen Excess
- Trial name
- E2 (NCT05587920)
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Army Health Branch, British Army
Infertility
Hypnopuncture for In Vitro Fertilization (IVF)
Infertility is a common and distressful problem for many couples, with assisted reproductive techniques (ART) such as IVF and ICSI, with slightly more than 34% pregnancies per cycle.
- Trial name
- NCT00544401
- Testing
- Hypnopuncture (Hypnosis+Acupuncture)
- Where
- Israel
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Hypertension, Vascular Stiffness
Cardiovascular Effects of EVOO in Healthy Reproductive-aged Women
This study aims to compare changes in cardiovascular function and markers of inflammation and metabolic dysfunction in women randomized to treatment with extra virgin olive oil (EVOO) versus those randomized to treatment with a…
- Trial name
- NCT03820336
- Testing
- Extra Virgin Olive Oil, Control Oil
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Vermont Medical Center
Obesity
Folic Acid Supplementation in Women of Child Bearing Age
The objective of this study is to identify genes whose expression is potentially modifiable due to changes in folate intake and help delineate mechanisms accounting for the variability in individual response to folic acid…
- Trial name
- FASUPP (NCT01841658)
- Testing
- Folic acid
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Georgia