Clinical trials: Reproductive Effects
Overweight, Obesity
Effect of Weight Loss on Reproductive Function in Overweight Men
Obesity has been found to be a risk factor for female infertility. Studies have indicated that obese men often have poor semen quality and require increased time to make partner pregnant.
- Trial name
- NCT00934765
- Testing
- weight loss
- Where
- Norway
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Oslo University College
Obesity; Endocrine
Time-restricted Eating and High Intensity Interval Training Among Women
This project will determine the independent and combined effects of high intensity interval training and time-restricted eating on blood sugar regulation among women in reproductive-age who have overweight or obesity.
- Trial name
- NCT04019860
- Testing
- High Intensity Interval Training, Time-Restricted Eating
- Where
- Norway
- Volunteers
- 131 people
- Sponsor
- Norwegian University of Science and Technology
Controlled Ovarian Stimulation, Infertility
Study to Examine Effect of Recombinant Luteinizing Hormone (r-Lh) and Recombinant Human Chorionic Gonadotropin (r-hCG) for Ovarian Stimulation in Assisted Reproduction Techniques (ART)
The study is a prospective, randomised, controlled, and non-blinded multi-center pilot study to evaluate endocrine efficacy of recombinant luteinizing hormone versus recombinant human chorionic gonadotropin administered during…
- Trial name
- NCT01339299
- Testing
- recombinant luteinizing hormone (r-LH), recombinant human chorionic gonadotropin (r-hCG)
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Regionshospitalet Viborg, Skive
Male Infertility, Oligoasthenospermia
Investigation of the Effects of Stem Cell Supportive Treatment on Semen Parameters and Assisted Reproductive Techniques (ICSI) in Infertile Male Patients With Oligoasthenospermia(Decrease Sperm Number and Quality)
This study evaluated whether Stemregen® dietary supplementation could improve sperm quality and assisted reproductive treatment outcomes in men with severe oligoasthenozoospermia who had previously experienced at least one failed…
- Trial name
- STEMRN (NCT07800052)
- Testing
- Stemregen
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kocaeli University
Iron Deficiency Anemia
Effect of Multiple Micronutrient Fortified Bread Consumption on Iron Deficiency Anemia in Women of Reproductive Age
The project aims to assess if consuming two slices of multi-fortified bread daily for 120 days is effective in reducing iron deficiency anemia in women of reproductive age through a three-arm randomized trial.
- Trial name
- NCT05103709
- Testing
- MULTI-FORTIFIED, FORTIFIED
- Where
- Peru
- Volunteers
- 351 people, healthy volunteers welcome
- Sponsor
- Universidad Peruana Cayetano Heredia
Reproductive System Disorder, Urinary Incontinence
The Effect of Polycystic Ovary Syndrome on Pelvic Floor Structure and Function
Polycystic Ovarian Syndrome (PCOS) is the most common endocrinological disorder in women of reproductive age, and its prevalence is reported to be 6-21% in women aged 15-49 (1).
- Conditions
- Reproductive System Disorder, Urinary Incontinence, Urogenital Disease, Polycystic Ovary Syndrome
- Trial name
- NCT04398186
- Testing
- Anogenital distance measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Giresun University
Folate Deficiency, Iodine Deficiency
Acceptability and Nutritional Impact of Double-fortified Salt Containing Iodine and Folic Acid
The overarching objective of this two-phase project is to assess the effects of fortifying iodized salt with folic acid on improving women's folate status.
- Conditions
- Folate Deficiency, Iodine Deficiency, Anemia Macrocytic, Anemia Deficiency
- Trial name
- DFS-IoFA-2 (NCT06223854)
- Testing
- Iodized salt, Experimental: Iodized salt with lower-dose folic acid fortification, Experimental: Iodized salt with higher-dose folic acid fortification
- Where
- Ethiopia
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Infertility, Female
The Effect of the Mind/Body Program for Fertility, Hungarian Version, on Well-Being and Assisted Reproduction Outcomes
Involuntary childlessness is an emotionally stressful experience; however, psychosocial counseling is typically not available in Hungarian routine fertility care.
- Trial name
- NCT04151485
- Testing
- Mind/Body Program for Fertility (Domar et al., 2011), Fertility Support Program
- Where
- 2 sites in Hungary
- Volunteers
- 177 people
- Sponsor
- Semmelweis University
Endometriosis, Uterine Fibroids
A Phase 1 Clinical Study to Evaluate the Effects of SHR7280 on the Pharmacokinetics of Midazolam, S-warfarin, Omeprazole, Digoxin, and Rosuvastatin in Healthy Subjects
The purpose of this study is to evaluate the effects of SHR7280 on the pharmacokinetics of midazolam, S-warfarin, omeprazole, digoxin and rosuvastatin in healthy subjects.
- Conditions
- Endometriosis, Uterine Fibroids, Assisted Reproduction
- Trial name
- NCT06949124
- Testing
- SHR7280 Tablets
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Colorectal Cancer, Colorectal Neoplasms
Changes in Reproductive and Sexual Health in People With Early Onset Colorectal Cancer
The purpose of this study is to find out how cancer treatments (chemotherapy and/or radiation therapy) affect reproductive and sexual health in people with early onset colorectal cancer.
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Colorectal Carcinoma
- Trial name
- NCT04812912
- Testing
- Hormone biomarker analysis, QoL Questionnaires
- Where
- 7 sites in United States
- Volunteers
- 120 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Infertility, Female
Exploratory Study Assessing Synchronisation of Egg Sacs With Degarelix
The main purpose of this clinical research study is to investigate if degarelix can synchronise the growth of the egg sacs in the ovaries and if degarelix has any effect on the lining of the womb.
- Trial name
- NCT00434122
- Testing
- Degarelix mid-luteal, 2.5 mg
- Where
- 4 sites in Belgium, Czechia and 1 more
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Healthy, Deficiency Disease
Effects of Dietary Carbohydrate and Fat on Hormones
This study will try to determine if intake of dietary fats or carbohydrates influences the tendency to gain weight or accumulate body fat.
- Trial name
- NCT00016848
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Community-dwelling Older Adults
Creative Dance Effects on Community-dwelling Older Adults
The aim of present study is to analyze the effect of a Creative Dance program on well-being, physical function, body awareness, and rhythm perception and reproduction of community-dwelling older adults.
- Trial name
- NCT04311931
- Testing
- Active Dance Program
- Where
- Portugal
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Évora
Embryo Implantation
Intramuscular Injection of Human Chorionic Gonadotropin in Frozen Embryo Transfer Cycles
This study is a randomized controlled clinical trial to compare the pregnancy outcomes of infertile women with frozen embryo transfer.
- Trial name
- NCT04855383
- Testing
- The effect of intramuscular injection of triple doses of human chorionic gonadotropin in frozen embryo transfer cycles
- Where
- Iran
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Hypoxia, Hysteroscopy
The Effects of Remimazolam on the Incidence of Severe Hypoxia During Sedated Hysteroscopy for Assisted Reproduction in Overweight or Obese Patients
Hypoxia is a common adverse event during sedated hysteroscopy for assisted reproduction, and it is more likely to occur in overweight or obese patients.
- Conditions
- Hypoxia, Hysteroscopy, Overweight or Obesity
- Trial name
- RP (NCT06187896)
- Testing
- remimazolam, Propofol
- Where
- China
- Volunteers
- 600 people
- Sponsor
- RenJi Hospital
Birth Control Behavior, Reproductive Health Attitude
Transtheoretical Model Counseling in Postpartum Contraception
The purpose of this study is to evaluate the effect of contraceptive method counseling offered to primiparous women between the ages of 18-45 in the postpartum period by motivational interviewing method based on the…
- Trial name
- NCT07784738
- Testing
- Effect of Transtheoretical Model-Based Counseling on Postpartum Contraceptive Uptake
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Male Infertility
Effect of Eurycoma Longifolia (DLBS5055) and Multivitamins (Vitamin C+Vitamin E+ β-carotene) for Infertile Males
Infertility is defined as the inability of a couple to get pregnant after one year of regular and unprotected sexual intercourse.
- Trial name
- NCT06100432
- Testing
- DLBS5055 200mg, Multivitamin (Vitamin C 500mg + Vitamin E 100IU + Beta Carotene 10000IU)
- Where
- Indonesia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Duta Wacana Christian University
Intrauterine Adhesion
Effects of Aspirin on Uterine Endometrial Repair Severe Intrauterine Adhesion
This study aimed To investigate the effects of estrogen in combination with aspirin and intrauterine balloon on the uterine endometrial repair and reproductive prognosis in patients after surgery for severe intrauterine adhesion .
- Trial name
- NCT02744716
- Testing
- Aspirin, intrauterine balloon
- Where
- China
- Volunteers
- 114 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Pregnancy Result Rape
The Effect of Luteinizing Hormone (LH) Supplementation Following Gonadotropin-releasing Hormone (GnRH) Antagonist Administration in Advanced Reproductive Ageing Women Undergoing IVF and Embryo Transfer (IVF/ET)
To explore whether recombinant LH (rLH) supplementation (Leuveris) to recombinant follicle stimulating hormone (rFSH) following GnRH antagonist treatment has an advantage in infertile women with advanced reproductive ageing…
- Trial name
- NCT01016210
- Testing
- Leuveris
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Fibroid; Uterus Tumor, Complicating Pregnancy, Infertility, Female
Esmya Versus Surgery Before IVF/ICSI
Studying the possible outcome differences between surgery or medical treatment with ulipristalacetate (UPA) solely before 'in-vitro fertilisation/intracytoplasmic sperm injection' (IVF/ICSI) treatment in infertile couples.
- Conditions
- Fibroid; Uterus Tumor, Complicating Pregnancy, Infertility, Female, Surgical Procedure, Unspecified
- Trial name
- NCT04028986
- Testing
- Ulipristal Acetate 5 MG Oral Tablet
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universitair Ziekenhuis Brussel