Clinical trials: Reproductive Effects
Post Cesarean Scar Defect, Hysteroscopy
Effects of Hysteroscopy and Transvaginal Surgery on Reproductive Prognosis in Patients With Post Cesarean Scar Defect
The study is to compare hysteroscopic repair and transvaginal intervention for correcting uterine defect in patients with post cesarean scar defect (PCSD) and the reproductive prognosis.
- Trial name
- NCT04096677
- Testing
- hysteroscpy
- Where
- 2 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Changes in sncRNA in Sperm, Male Fertility
The Effects of Diet on Small Non-coding RNA i Sperm Cells and the Possible Effects on Reproductive Success: Diet Intervention Effects on Sperm
In this study, patients with infertility treated with IVF at the Center of Reproductive Medicine in Linköping, Sweden, will receive recipes and food according to Nordic dietary guidelines.
- Conditions
- Changes in sncRNA in Sperm, Male Fertility, RNA Profile
- Trial name
- DIET-IS (NCT06831292)
- Testing
- Diet intervention NMR
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Ostergotland County Council, Sweden
Sperm Count, Low, Reproductive Sterility
A Retrospective Study on the Effect of Male Progressive Sperm Count After Semen Pretreatment on ICSI Fertilization Outcome
The investigators plan to retrospectively analyze clinical data from 14,189 fresh ICSI cycles in Reproductive and Genetic Hospital of CITIC-Xiangya from January 2016 to December 2017.The investigators will regard total…
- Trial name
- NCT03594201
- Testing
- semen pretreatment
- Where
- China
- Volunteers
- 12,215 people
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Adolescent Behavior, Sexual Behavior
Assessing the Preliminary Effects of a Multisectoral Agricultural Intervention on Adolescent Girls' Health
The goal of this study is to understand how the Shamba Maisha household agricultural and economic intervention impacts the sexual, reproductive, and nutritional health of adolescent girls.
- Conditions
- Adolescent Behavior, Sexual Behavior, Reproductive Behavior
- Trial name
- NCT03741634
- Testing
- Multi-sectoral agricultural intervention
- Where
- 16 sites in Kenya
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pregnancy
Michigan Contraceptive Access, Research, and Evaluation Study Children: Phase 1
This project builds on the Michigan Contraceptive Access Research and Evaluation Study (M-CARES) to evaluate the long-term effects of mothers' access to free contraceptives and reductions in unintended pregnancies on their…
- Trial name
- M-CARES-K (NCT04371900)
- Testing
- Mother receives voucher valued at 100% of cost of name-brand IUD (March 4, 2019-March 31, 2023), Mother receives voucher valued at 50% of cost of name-brand IUD (August 26, 2018-March 3, 2019)
- Where
- 9 sites in United States
- Volunteers
- 4,700 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Environmental Exposure, Infertility
The Effect of Periconceptional Phthalates Exposure on Couples' Reproductive Health
The study is a prospective cohort study, which is aiming to explore periconceptional phthalates exposure and its potential epigenetic effect on fertility, embryo development, and neonatal outcomes.
- Trial name
- NCT03679000
- Where
- China
- Volunteers
- 2,122 people
- Sponsor
- Tongji Hospital
Ectopic Pregnancy
Reproductive Health Education, Birth Control and Sexual Quality of Life in Ectopic Pregnancy
Ectopic pregnancy (EP) is defined as the implantation of a fertilized ovum outside the uterine cavity, most commonly in the fallopian tubes.
- Trial name
- NCT07431411
- Testing
- Reproductive Health Counseling and Educational Brochure
- Volunteers
- 102 people
- Sponsor
- Buket Kömürcü
Contraception Behavior, Contraceptive Usage
Effects of One-to-one Service on the Continuation and Satisfaction of Contraceptive Use.
This study aims to explore the impact of a mobile based one-to-one service model on improving the continuation and satisfaction of combined injectable contraceptive use, and improve the utilization and acceptability of efficient…
- Trial name
- NCT05362019
- Testing
- Compound Norethisterone Enanthate Injection, One-to-one Service, Family Planning Service
- Where
- 8 sites in China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Research Institute for Family Planning, China
Sexually Transmitted Infection (STI), HIV
Assessing the Effects of a Multisectoral Agricultural Intervention on the Reproductive and Sexual Health of Adolescent Girls and Young Women
In Kenya, HIV incidence among adolescent girls and young women (AGYW) ages 15-24 years is 1-2 per 100 person-years and approximately 30% of AGYW have had at least one sexually transmitted infection (STI).
- Conditions
- Sexually Transmitted Infection (STI), HIV, Food Insecurity, Mental Health
- Trial name
- Vijana Shamba (NCT06953310)
- Where
- Kenya
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Female Infertility
Hormone Evaluation in Artificial Reproductive Technology
The aim is to be able to predict the hormonal response according to gonadotropin receptor genotype and hormone type used for treatment of women undergoing in vitro fertilization or egg donation.
- Trial name
- HEART (NCT03737253)
- Testing
- Follitropin alpha, Menotropin
- Where
- 2 sites in Poland, Sweden
- Volunteers
- 810 people
- Sponsor
- Lund University
Failure After Assisted Reproductive Technology
Observation on the Curative Effect of Assisted Reproduction by TCM Multi-channel Interventional Therapy
Objective: To evaluate the curative effect of TCM multi-channel interventional therapy on women with ART Failure; to compare the curative effect of the dual therapy and triple therapy on women with ART Failure; to choose the best…
- Trial name
- NCT03078205
- Testing
- The dual therapy, The triple therapy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Ovarian Reserve, SARS-CoV-2 Infection
Effect of Sars-cov-2 on Donor Oocyte Quality and Quantity, a Multicenter Retrospective Study.
Purpose: To determine the impact of SARS-CoV-2 infection and immunization on ovarian response to controlled ovarian stimulation (COS) and embryo development after in vitro fertilization (IVF) Methods: A retrospective multicentric…
- Conditions
- Ovarian Reserve, SARS-CoV-2 Infection, Blastocyst
- Trial name
- NCT05562479
- Testing
- Sars Cov 2 infection, Sars Cov 2 vaccination
- Where
- Colombia
- Volunteers
- 428 people, healthy volunteers welcome
- Sponsor
- Novafem
Subfertility
Effect of Endometrial Scratching on Assisted Reproduction Outcomes: a Randomized Controlled Trial
To examine whether endometrial scratching (or injury) using a Pipelle endometrial sampler, performed on the first seven days of the menstrual cycle, is able to improve pregnancy rates in women who will be submitted to a fresh…
- Trial name
- NCT02180256
- Testing
- Endometrial Scratching
- Where
- Brazil
- Volunteers
- 107 people
- Sponsor
- University of Sao Paulo
Transgenderism, Reproductive Issues
Androgen Effects on the Reproductive Neuroendocrine Axis
This research study investigates whether male-level exogenous androgens inhibit the reproductive neuroendocrine axis in otherwise healthy (non-PCOS) females.
- Trial name
- NCT06450405
- Testing
- Testosterone Cypionate 50 MG/ML Injectable Solution
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Female Infertility, Reproductive Disorders
Effect of Comprehensive Spa Rehabilitation on Female Infertility: A Clinical Study in Adult Women (Infertility-Spa)
This is a prospective, single-arm, pretest-posttest study evaluating the effects of a 21-day comprehensive spa treatment (Komplexní lázeňská léčebně rehabilitační péče, KLP) on female infertility at spa facility in Františkovy…
- Conditions
- Female Infertility, Reproductive Disorders, Recurrent Pregnancy Loss
- Trial name
- NCT07542600
- Testing
- Comrehensive Spa Treatment (KLP)
- Where
- Czechia
- Volunteers
- 55 people
- Sponsor
- Institute of Spa and Balneology, public research institution
Infertility
Evaluation of SiD's System for Improving Assisted Reproduction Treatments
According to the WHO, infertility affects 15% of reproductive age couples worldwide. Among the assisted reproductive technologies available for patients with infertility, intracytoplasmic sperm injection (ICSI) has become one of…
- Trial name
- NCT05611164
- Testing
- Software assisted selection of individual spermatozoa for intracytoplasmic sperm injection
- Where
- 2 sites in Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IVF 2.0 Limited
Iron Deficiency, Iron Deficiency Anaemia
Assessing the Effect of a Mineral-enriched Powder on Iron Deficiency in Women of Reproductive Age
The goal of this clinical trial is to determine if taking a mineral-enriched powder can raise blood iron levels compared to a placebo powder in reproductive-aged women with iron deficiency.
- Trial name
- NCT05990166
- Testing
- Mineral-enriched powder
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Carleton University
Contraception
Compare Daily Ulipristal Acetate and Combined Oral Contraceptive Effects on Breast Epithelial Cell Proliferation
Breast cancer accounts for almost a quarter of all cancers in women. In the United States (U.S.) in 2014, more than 230,000 women were diagnosed and 40,000 died of breast cancer.
- Trial name
- NCT02922127
- Testing
- Ulipristal Acetate, Combined Oral Contraceptive Pill
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Columbia University
Sterility
Low Molecular Weight Heparin to Improve Pregnancy Outcome in Patients With Recurrent Implantation Failure
The objective of this study is to determine the effect of Bemiparin, a low molecular weight heparin, on implantation rate in women with unexplained recurrent implantation failure undergoing IVF/ICSI treatment.
- Trial name
- BRIF (NCT02607319)
- Testing
- Bemiparin sodium
- Where
- Lebanon
- Volunteers
- 165 people
- Sponsor
- American University of Beirut Medical Center
Contraception, Contraceptive Usage
Advance Provision of Postpartum Emergency Contraception and Its Effects on Reproductive Autonomy
This study will entail provision of ulipristal acetate (UPA) for emergency contraception (EC) in the postpartum period for patients who have not chosen to initiate a highly effective form of contraception and study the use of EC…
- Conditions
- Contraception, Contraceptive Usage, Reproductive Issues
- Trial name
- NCT05285605
- Testing
- Ulipristal Acetate
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Northwestern University