Clinical trials: Reproductive Effects
Reproductive Health
Fertility and Preconceptional Health Knowledge and Attitudes Among University Students
Fertility means being fertile, that is, having the ability to reproduce. Fertility awareness means that individuals know and avoid the anatomy and physiology of the reproductive system, the importance of fertility, fertility…
- Trial name
- NCT06254937
- Testing
- Reproductive Life Plan training
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Ebru Cirban Ekrem
Obstructive Sleep Apnea
SLEEP AND OSA ON REPRODUCTIVE FUNCTION IN MEN
In view of the hormonal changes induced by both sleep deprivation and obstructive sleep apnea syndrome (OSA), and the importance of maintaining these hormones in reproductive processes.
- Trial name
- PSAR01 (NCT01884454)
- Testing
- Sleep deprivation
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Adenomyosis of Uterus, Infertility Assisted Reproductive Technology
Does The Addition Of Letrozole To Ultra-Long GnRH Agonists Help Adenomyosis Patients in ART? The AURA Trial
The AURA Trial seeks to improve fertility treatment for women affected by a condition known as adenomyosis. Adenomyosis often leads to heavy menstrual bleeding, pelvic pain, dyspareunia and can make it more difficult to achieve…
- Trial name
- AURA (NCT06985186)
- Testing
- Ultra-Long GnRH Agonists + Letrozole, Ultra-Long GnRH Agonists
- Where
- Spain
- Volunteers
- 162 people
- Sponsor
- University of Palermo
Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment
Sildenafil in Treating Erectile Dysfunction in Patients With Prostate Cancer
RATIONALE: Sildenafil may be effective in helping patients who have undergone treatment for prostate cancer to have an erection for sexual activity and may improve sexual satisfaction and quality of life.
- Conditions
- Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment, Radiation Toxicity, Sexual Dysfunction
- Trial name
- NCT00057759
- Testing
- sildenafil citrate
- Where
- 30 sites in United States
- Volunteers
- 115 people
- Sponsor
- Radiation Therapy Oncology Group
Contraceptive Usage, HIV Infections
Effect of Dolutegravir on Etonogestrel Levels in HIV-infected Women in Botswana
The primary aim is to assess if etonogestrel (ENG) implant users taking dolutegravir (DTG) have a 20% or greater change in their ENG plasma levels, compared to women taking no antiretroviral therapy (ART).
- Conditions
- Contraceptive Usage, HIV Infections, Drug Interaction
- Trial name
- NCT03336346
- Testing
- dolutegravir, ENG implant, Efavirenz
- Where
- Botswana
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Columbia University
Anxiety Disorder, Cervical Cancer
Scripted Sexual Health Informational Intervention in Improving Sexual Function in Patients With Gynecologic Cancer
This randomized pilot clinical trial studies the feasibility of a pre-operative and/or post-operative scripted sexual health informational intervention and how well it works in improving sexual function in patients with…
- Conditions
- Anxiety Disorder, Cervical Cancer, Endometrial Cancer, Female Reproductive Cancer
- Trial name
- NCT02096783
- Testing
- informational intervention, counseling intervention, questionnaire administration
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Wisconsin, Madison
Dilated Cardiomyopathy
Bromocriptine in Dilated Cardiomyopathy Among Women of Reproductive Age
Dilated cardiomyopathy (DCM) is a condition associated with left and /or right ventricular (LV) dilatation and systolic dysfunction without coronary artery disease or abnormal loading circumstances proportionate to the severity…
- Trial name
- NCT06250257
- Testing
- Bromocriptine mesylate plus standard GDMT
- Where
- Ethiopia
- Volunteers
- 112 people
- Sponsor
- Jimma University
Effect of Adding GnRHa as Luteal Phase Support in Antagonist ART Cycles
Role of Triptorelin 0.1 mg as a Luteal Phase Support in Assisted Reproductive Technique After Embryo Transfer : a Randomized Controlled Trial
There is still controversy over the best LPS agent and protocol and its dose and duration as well as the time of initiation and cessation.
- Trial name
- NCT04087408
- Testing
- Effect of adding gonadotropins releasing hormone agonist to progesterone for luteal phase support in assisted reproductive technique )antagonist cycles(: a randomized controlled trial
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Moustafa Mohammed Abouelea
Infertility, Female, Assisted Reproduction
Effects of Intramural Fibroids on IVF Outcome
A cohort study involving 200 women candidate for IVF / ICSI cycles . The participants will be assessed through full history-taking with special consideration to age and the duration, type, and cause of infertility.
- Trial name
- NCT03904355
- Testing
- Gonadotropins, human chorionic gonadotropin, Ovum pick up
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Transgenderism, Reproductive Issues
Androgen Effects on the Reproductive Neuroendocrine Axis, 2025 Version
This research study investigates whether male-level exogenous androgens inhibit the reproductive neuroendocrine axis in otherwise healthy (non-PCOS) females.
- Trial name
- NCT07092527
- Testing
- Testosterone Cypionate 50 milligrams per millileter (mg/mL) Injectable Solution
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Pregnancy and Medically Assisted Reproduction
Antenatal Stress and Infants In MAR
The goal of this observational longitudinal study is to examine the association between prenatal psychological and biological stress and neonatal health outcomes in couples who conceived through medically assisted reproduction.
- Trial name
- SARA (NCT07408453)
- Testing
- Diagnostic procedures
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
In Vitro Fertilization, Intracytoplasmic Sperm Injection
Effect of GnRH Agonist vs GnRH Antagonist on IVF/ICSI Outcomes in Polycystic Ovary Syndrome Patients.
This prospective, non-randomised, open-label, clinical trial is conducting on polycystic ovary syndrome (PCOS) subjects to compare the effects of two pituitary suppression regimens; GnRH Agonist-Long Protocol and GnRH…
- Conditions
- In Vitro Fertilization, Intracytoplasmic Sperm Injection, Infertility, Polycystic Ovary Syndrome
- Trial name
- NCT04727671
- Testing
- Triptorelin acetate, Cetrorelix, recombinant-FSH or recombinant-FSH + human Menopausal Gonadotropin
- Where
- Syria
- Volunteers
- 50 people
- Sponsor
- Damascus University
Infertility, Female, Anxiety
Multifaceted Benefits of Auricular Point Sticking for IVF Patients: Psychological Well-being, Sleep, and Treatment Outcomes
The goal of this clinical trial is to evaluate whether the complementary intervention of auricular point sticking therapy (APST) can improve pregnancy outcomes by ameliorating psychological distress and sleep quality in female…
- Conditions
- Infertility, Female, Anxiety, Assisted Reproductive Techniques, Dyssomnias
- Trial name
- NCT07409792
- Testing
- auricular point sticking therapy, Conventional Artificial Cycle Therapy
- Where
- China
- Volunteers
- 178 people
- Sponsor
- Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University
Salidroside, Randomized Controlled Trial
Effect of Salidroside on Pregnancy Outcomes in High Childbearing Age Patients in Viro Fertilization
With the decreasing of birth rate and population in our country, population problem has become a long-term and strategic problem.
- Conditions
- Salidroside, Randomized Controlled Trial, In Vitro Fertilization, Assisted Reproductive Technology
- Trial name
- NCT06990685
- Testing
- Salidroside
- Where
- China
- Volunteers
- 370 people
- Sponsor
- The Second Hospital of Shandong University
Hypertension, Vascular Stiffness
Cardiovascular Effects of EVOO in Healthy Reproductive-aged Women
This study aims to compare changes in cardiovascular function and markers of inflammation and metabolic dysfunction in women randomized to treatment with extra virgin olive oil (EVOO) versus those randomized to treatment with a…
- Trial name
- NCT03820336
- Testing
- Extra Virgin Olive Oil, Control Oil
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Vermont Medical Center
Polycystic Ovarian Syndrome in Adolescent Females, Obesity (Disorder)
Effects of Glucagon-like Peptide-1 (GLP-1) Agonist in Neuro-reproductive Function in Obese Adolescent Females With Polycystic Ovary Syndrome (PCOS)
The prevalence of childhood obesity in the United States has more than tripled in the past four decades affecting one in every five adolescent girls and is disproportionally higher among racial and/or ethnic minorities.
- Trial name
- NCT07169136
- Testing
- GLP-1 Receptor Agonists
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Nemours Children's Clinic
Women of Reproductive Age, Diabetes Mellitus
Rationale and Design of Diabetes Management With Curcumin and Saffron (DMCS): a Randomised, Three Blind -Blind, Placebo-controlled Study
## Study Hypotheses Summary: Primary Hypothesis: Women with diabetes mellitus receiving the intervention will exhibit significantly lower levels of sugar indicators (FBS, HA1c, 2HPP) and lipid indicators (LDL, HDL, TG) compared…
- Trial name
- NCT06413238
- Volunteers
- 120 people
- Sponsor
- Fateme Moshirenia
Obesity
Folic Acid Supplementation in Women of Child Bearing Age
The objective of this study is to identify genes whose expression is potentially modifiable due to changes in folate intake and help delineate mechanisms accounting for the variability in individual response to folic acid…
- Trial name
- FASUPP (NCT01841658)
- Testing
- Folic acid
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Infertility
Physiotherapy in Assisted Reproductive Treatment
Research examines the effect of physiotherapy on treatment success by assisted reproductive technologies. It is based on a treatment of infertility by physiotherapeutic intervention after which the participants will undergo a…
- Trial name
- NCT04971824
- Testing
- Physiotherapeutic intervention
- Where
- Czechia
- Volunteers
- 42 people
- Sponsor
- Klaudia Fabičovic, PT
Polycystic Ovary Syndrome
Effect of Weight & Insulin Sensitivity on Reproductive Function in PCOS: Studies in Skeletal Muscle & Adipose
The overall objective of this ancillary study is to obtain skeletal muscle and subcutaneous adipose tissue biopsies from women with polycystic ovary syndrome enrolled in the PULSE Study (NCT01482286).
- Trial name
- PULSE-A (NCT01775176)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Pennington Biomedical Research Center