Clinical trials: Reproductive Effects
Healthy
Immediate Effect of Light on Reproductive Hormones in Women: a Role of the Spectrum
The study investigates an acute effect of white-appearing LED light (with a peak in blue portion) vs. red LED light of similar irradiance on reproductive hormones in healthy women.
- Trial name
- NCT00467805
- Testing
- Light therapy
- Where
- Russia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Russian Academy of Medical Sciences
Menstrual Disorder, Premature Ovarian Failure
The Effect of HPV Vaccine on Menstrual Cycle in Women of Reproductive Age
Cervical cancer is one of the most common cancer in women, making it the fourth largest cause of female cancer mortality worldwide.
- Trial name
- NCT05838157
- Testing
- prophylactic HPV vaccine(bivalent HPV、quadrivalent HPV、9-valent HPV)
- Where
- 2 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Infertility Assisted Reproductive Technology, Infertility, Female
The Effect of Stress Ball Used During Intra Uterine Insemination on Pain, Anxiety, Comfort and Physiological Parameters
This study aimed to determine the effects of holding the patient's hand and using a stress ball during the Intrauterine Insemination procedure on pain, anxiety, comfort, and physiological parameters.
- Trial name
- NCT06759337
- Testing
- Stress Ball Group, Hand-Holding Group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- TC Erciyes University
Contraceptive Usage, Family Planning
Effect of Male Involvement in Family Planning Education on Contraceptive Use
This study aimed to examine the effect of Male Involvement in Family Planning Education on Contraceptive Use Among Married Couples in the Pastoralist Community of Fentale District, Eastern Ethiopia.
- Trial name
- NCT06450756
- Testing
- Couples arm, Male arm
- Where
- Ethiopia
- Volunteers
- 1,496 people
- Sponsor
- Jimma University
Anxiety, Assisted Reproductive Treatments
Virtual Reality for Anxiety Relief in Infertile Women
This study examines the impact of virtual reality (VR) applications on anxiety levels before and after embryo transfer procedures.
- Conditions
- Anxiety, Assisted Reproductive Treatments, Women, VR
- Trial name
- NCT07020975
- Testing
- VR Glasses
- Where
- Cyprus
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cyprus Aydin University
Infertility
Multi-factorial Analysis of the Follicular Fluid Milieu to Explore the Discrepant Effect of Follicular Fluid Endometrial Flushing on Outcome of Assisted Reproduction Trial
Patients \& Methods: Eighty infertile women were randomly categorized into: Group EF (n=40) had EF after oocyte retrieval and Control group (n=40) did not have EF.
- Trial name
- NCT02468258
- Testing
- endometrial flushing
- Where
- Egypt
- Sponsor
- Benha University
Reproductive Endocrinology, Fertility
Preimplantation Genetic Diagnosis (PGD) With Gonadotropin-releasing Hormone (GnRH) Agonist Versus Antagonist
The aim of our study is to define the optimal ovarian stimulation protocol concerning PGD and for this reason we plan a randomized controlled trial (RCT) comparing gonadotropin-releasing hormone (GnRH) agonist protocol versus…
- Conditions
- Reproductive Endocrinology, Fertility, Optimal Stimulation Protocol
- Trial name
- Avanti (NCT01888744)
- Testing
- GnRH agonist, GnRH antagonist, hP-hMG
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- Universitair Ziekenhuis Brussel
Polycystic Ovary Syndrome
Effect of Weight and Insulin Sensitivity on Reproductive Function in PCOS
Polycystic ovary syndrome (PCOS) is the most common reproductive disorder in women of reproductive age and despite decades of research the etiology the disorder is not known.
- Trial name
- PULSE (NCT01482286)
- Testing
- Metformin, Dietary Restriction, Exercise Training
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Pennington Biomedical Research Center
Fertility Disorders
Effect of Oocyte Denudation Time and Intracytoplasmic Sperm Injection Time on Embryo Quality
An observational analytic retrospective study was conduct using cross-sectional study. The subject were oocytes from in-vitro fertilization procedures using the ICSI method at the assisted reproductive technology clinic in a…
- Trial name
- NCT05448859
- Testing
- intracytoplasmic sperm injection
- Volunteers
- 200 people
- Sponsor
- Universitas Padjadjaran
Female Infertility, Reproductive Health
A Clinical Trial to Evaluate the Effects of a Supplement on Markers of Female Fertility
This study evaluates the effects of a daily dietary supplement (WeNatal For Her) on markers of female fertility, reproductive health, and sexual health over three menstrual cycles.
- Conditions
- Female Infertility, Reproductive Health, Fertility, Hormonal Imbalance
- Trial name
- NCT07740187
- Testing
- WeNatal For Her Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- WeNatal
Effects of Chemotherapy
The Longitudinal Ovarian Reserve Study
Postmenarchal female cancer patients scheduled to undergo cancer therapy may enroll in this study to assess changes in existing and novel surrogate measures of fertility potential before, during and after chemotherapy.
- Trial name
- NCT02395341
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania
Bacterial Vaginoses, Infertility, Female
The Effect of Clindamycin and a Live Biotherapeutic on the Reproductive Outcomes of IVF Patients With Abnormal Vaginal Microbiota
Study question: Does antibiotic alone or in combination with live biotherapeutic treatment of an abnormal vaginal microbiota improve the reproductive outcomes of IVF couples? Study hypothesis: The investigator hypothesize that…
- Trial name
- NCT05166746
- Testing
- Clindamycin
- Where
- 4 sites in Denmark
- Volunteers
- 333 people
- Sponsor
- Peter Humaidan
Infertility, Ovulation Induction
A Clinical Trial to Determine the Effect of Lutropin Alfa on Embryo Quality and Implantation Rate in Advanced Reproductive Age
This is a multicentric, open, randomized, comparative trial aimed to assess the influence of recombinant luteinizing hormone (r-LH) supplementation during controlled ovarian stimulation (COS) in advanced reproductive age in terms…
- Trial name
- NCT01075815
- Testing
- Recombinant human luteinizing hormone (rhLH), Recombinant follicle-stimulating hormone (rFSH)
- Where
- Spain
- Volunteers
- 76 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Female Reproductive Cancer
Media Diversion in Improving Quality of Life in Patients With Recurrent Gynecologic Cancers Receiving Chemotherapy
This randomized clinical trial studies media diversion in improving quality of life in patients with recurrent gynecologic cancers receiving chemotherapy.
- Trial name
- NCT01901835
- Testing
- mind-body intervention procedure, survey administration, quality-of-life assessment
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of Wisconsin, Madison
Erectile Dysfunction
Assess the Effect of Daily Treatment of Vardenafil 20mg or Sildenafil 100mg and Placebo on Sperm Function
Assess the effect of daily treatment of vardenafil 20mg or sildenafil 100mg and placebo on sperm function
- Trial name
- NCT00655590
- Testing
- Levitra (Vardenafil, BAY38-9456), Sildenafil
- Where
- 18 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bayer
Assisted Reproductive Technology
Effect of Assisted Reproductive Technology on Cardiac Development in Childhood Assessed by Echocardiography
Assisted reproductive technology (ART) has extensively allowed pregnancy for infertile couples. However, the long-term effect of ART exposure on cardiovascular development and potential association with ART procedure and parental…
- Trial name
- Heart and ART (NCT02190422)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Nanjing Medical University
Implantation Failure
Vaginal Microbiome Influence on the Results of Assisted Reproduction Techniques
The objective of the present study to analyze the vaginal microbiome in patients who have not achieved gestation after oocyte donation treatment and after probiotic administration.
- Trial name
- RIFMicrobiome (NCT03153787)
- Testing
- Probiotic
- Where
- Spain
- Volunteers
- 69 people
- Sponsor
- Instituto Bernabeu
Cardiopulmonary Disease
Effects of Secondhand Smoke on Flight Attendant Health
This is a study on a population of flight attendants who were exposed to occupational secondhand tobacco smoke (SHS). This research will examine associations between flight attendant SHS exposure and development of respiratory…
- Trial name
- FAMRI (NCT01639235)
- Where
- United States
- Volunteers
- 592 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Sexual Health, Reproductive Health
The Effect of Escape Room Game on Reproductive Health Knowledge and Gender Equality Perception
This study aims to evaluate the impact of an "escape room" educational game on university students' knowledge of sexual/reproductive health and their perceptions of gender equality.
- Conditions
- Sexual Health, Reproductive Health, Gender Equality, Health Education
- Trial name
- NCT07346313
- Testing
- Escape Room Game on Reproductive Health and Gender Equality, Standard Theoretical Education
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Polycystic Ovary Syndrome
Effects of Fenofibrate on Metabolic and Reproductive Parameters in Polycystic Ovary Syndrome
This is a prospective randomized, double-blind placebo-controlled trial of 6 months' duration evaluating the effect of fenofibrate (200 mg/day) in females with polycystic ovary syndrome and mild hypertriglyceridemia.
- Trial name
- NCT00884819
- Testing
- Fenofibrate
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's