Clinical trials: Research Participation, active
Gram Negative Pneumonia, Gram-Negative Bacterial Infections
Clinical Trial to Study the Efficacy and Safety of Fluorothiazinone (N.F. Gamaleya NRCEM) in Prophylaxis of Nosocomial Bacterial Infections With Participation of Patients on MV
This study is designed to evaluate the clinical and antibacterial efficacy, safety and pharmacokinetics of the drug Fluorothiazinone compared to placebo to prevent nosocomial gram-negative bacterial infections with participation…
- Conditions
- Gram Negative Pneumonia, Gram-Negative Bacterial Infections, Bacteremia Caused by Gram-Negative Bacteria
- Trial name
- NCT06135350
- Testing
- Fluorothiazinone, tablets 300 mg at a dose of 2400 mg/day
- Where
- 2 sites in Russia
- Volunteers
- 234 people
- Sponsor
- Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation
Cardiovascular Diseases (CVD)
Data Donation Model for Inclusive Cardiovascular Prevention Using the TRAIN Health Platform
Cardiovascular disease (CVD) is the leading cause of death in the Netherlands and worldwide. While prevention strategies have improved, many population groups, including women, individuals with a migration background, and people…
- Trial name
- DDM-TRAIN (NCT07238036)
- Testing
- Digital Lifestyle Feedback Module (optional)
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Soft Tissue Sarcoma
Investigative Analysis of Soft Tissue Sarcoma Clinical Trials: An Observational Study
Generally, specific demographic cohorts exhibit higher participation rates in medical research, yet there exists a scarcity of research elucidating the trial attributes impacting the engagement of these particular demographics.
- Trial name
- NCT06264505
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Smoking Cessation
A Culturally Tailored Smartphone Application for African American Smokers
The overall objectives of this research proposal, are to (a) create a smartphone application for smoking cessation (i.e., HealthyCells), which will be achieved by integrating two pre-existing evidence-based smartphone…
- Trial name
- HC (NCT05188287)
- Testing
- HealthyCells
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Cervical Cancer, Uterine Cervical Neoplasm
Research Project on Reminders and Self-Sampling Can Increase Participation in Gynecology Cell Sampling - Preventive Examination Against Cervical Cancer.
Prevention of cervical cancer with cervical screening is one of the most successful screening activities in medicine. In Sweden, screening was implemented in the 1960s and has since prevented tens of thousands of women from…
- Conditions
- Cervical Cancer, Uterine Cervical Neoplasm, Uterine Neoplasms, Genital Neoplasm
- Trial name
- NCT04061967
- Testing
- Sending of screening summon.
- Where
- 6 sites in Sweden
- Volunteers
- 20,000 people
- Sponsor
- Karolinska Institutet
Participation Rate, Patient, Clinical Trials
Patients' Refusal to Participate in Surgical Research: Prevalence, Attributed Factors, and How to Overcome
This study aims to investigate the prevalence of refusal of participation in surgical clinical trials in our community. Furthermore, it aims to highlight potential factors contributing to refusal of participation.
- Trial name
- NCT07838285
- Testing
- Questionnaire
- Where
- Egypt
- Volunteers
- 372 people
- Sponsor
- Mansoura University
Research Participation
CO-creating Novel, Feasible, and Inclusive Research Methods
The lessons researchers learn and evidence researchers discover from research studies are limited by who volunteered as participants in each research study.
- Trial name
- CONFIRM (NCT07489144)
- Testing
- Participant co-design
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Augusta University
Human Immunodeficiency Virus, Treatment Adherence
Data Science and Qualitative Research for Decision Support in the HIV Care Cascade
The goal of this study is to determine whether clinical prediction algorithms derived using statistical machine learning methods can be used to improve patient outcomes in large HIV care programs in sub-Saharan Africa and…
- Conditions
- Human Immunodeficiency Virus, Treatment Adherence, Treatment Compliance, Patient No Show
- Trial name
- CASCADE (NCT06604663)
- Testing
- Activation of the CDSS system
- Where
- Kenya
- Volunteers
- 80,000 people
- Sponsor
- Brown University
Acne
Exploring Acne Treatments Through Clinical Research Participation
The purpose of this study is to understand the lived experiences of acne patients enrolled in a related clinical trial testing a particular treatment.
- Trial name
- NCT07010458
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
IBM, IIM
MIHRA - Patient-Rooted Insights for Shaping Myositis Science (PRISMS)
Myositis diseases are each rare diseases. As in other rare diseases, people living with myositis diseases face physical and psychosocial challenges that may not be recognized in current research priorities.
- Conditions
- IBM, IIM, Myositis, Inflammatory Myopathy
- Trial name
- MIHRA-PRISMS (NCT07374107)
- Testing
- No intervention - qualitative and mixed methods investigations
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- Myositis International Health & Research Collaborative Alliance Foundation
Sick Leave, Quality Of Care
A Structured Method for Systematic and Integrated Occupational Safety and Health and Patient Safety Management Systems
The evidence unequivocally supports the association between work environment and patient safety. The negative impact of working conditions on both employee health and quality of care highlights the potential benefits of…
- Conditions
- Sick Leave, Quality Of Care, Occupational Health, Safety Culture
- Trial name
- SIOHPS (NCT06398860)
- Testing
- SIOHPS, Wait-list
- Where
- 2 sites in Sweden
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Region Västmanland
Transgender Persons
Research Participation With Transgender and Gender-Diverse Youth
Research has historically excluded the participation of transgender and gender-diverse people. The purpose of this research study is to find out about what goes into a transgender and gender-diverse youth's decision to…
- Trial name
- NCT05927350
- Testing
- Survey
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Virginia Commonwealth University
DSD, Hypospadias
Breaking Silence Through Story: A Narrative Medicine Intervention for Parents of Children With Urogenital Conditions
The goal of this clinical trial is to learn whether a journaling intervention can reduce stress and anxiety in parents of children with urogenital conditions (such as differences of sex development and hypospadias).
- Trial name
- NCT06989593
- Testing
- Narrative Medicine Journaling Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sarah Schlegel
HPV Vaccination, Uptake Vaccination
PREVENT HPV -Related Cancers Trial
This study will serve as one of the first to develop and test the effectiveness of strategies to promote HPV vaccination among diverse rural parents and caregivers of children ages 9-17 years in the Mountain West.
- Conditions
- HPV Vaccination, Uptake Vaccination, Series Completion
- Trial name
- NCT07217145
- Testing
- PREVENT
- Where
- United States
- Volunteers
- 1,455 people, healthy volunteers welcome
- Sponsor
- University of Utah
Mild Cognitive Impairment
Navigating the Clinical Research Process for Mild Cognitive Impairment
Participation in medical research usually favors a particular demographic group. But there is limited research available to explain what trial attributes affect the completion of these specific demographic groups.
- Trial name
- NCT06207903
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Pediatric Cancer
Multisite Implementation of COMPRENDO
COMPRENDO (ChildhOod Malignancy Peer Research NavigatiOn) is a multi-site randomized clinical trial (RCT) that uses a Hybrid Type 1 design, to test the effects of a clinical intervention on patient-level outcomes, while exploring…
- Trial name
- COMPRENDO (NCT06055296)
- Testing
- COMPRENDO Peer Navigation Intervention
- Where
- 4 sites in United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Hepatocellular Carcinoma, Cholangiocarcinoma
Targeted Navigation in Hepatocellular Carcinoma (HCC)
The investigators are trying to learn more about the personal perceptions and experiences regarding the needs of patients with liver cancer to help improve the care of all patients.
- Conditions
- Hepatocellular Carcinoma, Cholangiocarcinoma, Hepatobiliary Cancer
- Trial name
- NCT06260943
- Testing
- Target Navigation Pilot Program
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- University of Miami
Health Services Accessibility, Rural Health
Health Ahead Comparative Effectiveness Study
The Health Ahead Comparative Effectiveness Study is a pragmatic, parallel-arm interventional platform that systematically compares successive changes to preventive health screening on the path toward a fully automated screening…
- Conditions
- Health Services Accessibility, Rural Health, Medically Underserved Area, Preventive Health Services
- Trial name
- HACE (NCT07669168)
- Testing
- AI-Assisted Screening Interpretation (AI Reads), Human-Only Screening Interpretation
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- William Brandenburg, MD
Atopic Dermatitis
Investigating Participation Patterns of Patients in Atopic Dermatitis Clinical Trials
Clinical trials, specifically focused on atopic dermatitis, are crucial in assessing the safety and efficacy of new treatments. These trials serve as fundamental instruments in determining whether emerging medications outperform…
- Trial name
- NCT06174493
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
P. Aeruginosa, Baumannii
An Open Clinical Trial of the Safety and Efficacy of the Drug Fluorothiazinone, 300 Mg Tablets with the Participation of Adult Patients with Chronic Bacterial Cystitis"
This study is designed to evaluate the safety, clinical efficacy and antibacterial activity of the drug Fluorothiazinone, 300 mg tablets, (Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the…
- Conditions
- P. Aeruginosa, Baumannii, Klebsiella Pneumonia, E.coli Infections
- Trial name
- NCT06815549
- Testing
- Fluorothiazinone, tablets 300 mg, Nitrofurantoin 100 MG
- Volunteers
- 280 people
- Sponsor
- Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation