Clinical trials: Residual
Apnea, Hypoxia
Effects of Automated Adjustment of Inspired Oxygen With Combined Adaptive Mechanical Backup Ventilation as Compared to Automated Oxygen Adjustment Alone in Preterm Infants With Intermittent Hypoxemic Events During Non-invasive Ventilatory Support
In this 2-phase cross-over study the investigators test the hypothesis that automated adjustment of the inspired oxygen with the combined use of synchronized noninvasive SpO2-sensitive and apnea-sensitive backup-ventilation…
- Trial name
- NCT02774408
- Testing
- Saturation sensitive backup ventilation
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Amputation
Dynamic Management of Excess Residual Limb Pressure With New Smart Socket Technology/Intelligent Prosthetic Socket With Variable Volume and Elevated Vacuum Systems
This study centers around the imaging of internal structures of residual limb by means of modern radiographic imaging techniques (Dynamic Radiography-DRSA).
- Trial name
- SMARTsocket- (NCT01108536)
- Testing
- adaptive prosthetic socket
- Where
- 3 sites in United States, Cyprus
- Volunteers
- 60 people
- Sponsor
- University of Wisconsin, Milwaukee
Curarization, Postoperative Residual, Postoperative Pain Of Laparoscopic Surgery
Role of Curarization During Anesthesia for Laparoscopic Hysterectomy
The primary outcome of this study is to investigate whether deep NMB reversed with Sugammadex is superior to moderate NMB reversed with Neostigmine, in terms of overall pain in the first 48 hrs after laparoscopic hysterectomy…
- Conditions
- Curarization, Postoperative Residual, Postoperative Pain Of Laparoscopic Surgery, PONV
- Trial name
- NCT03519633
- Testing
- Sugammadex, Neostigmine
- Where
- Italy
- Volunteers
- 238 people
- Sponsor
- Campus Bio-Medico University
Infection, Surgical Site
Use of Real-time Fluorescence Imaging in Diabetic Foot Ulcers: the Impact of Colonization
The study evaluates the efficacy of fluorescence-guided de-colonization in patients with non-infected diabetic foot ulcers. The efficacy will also be compared between those who used artificial dermis and split-thickness skin…
- Trial name
- NCT05873049
- Testing
- MolecuLight
- Where
- Taiwan
- Volunteers
- 210 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Gastric Volume
Lollipop on Gastric Volume
To observe the effect of chewing lollipop on residual gastric volume in healthy volunteers with fasting.
- Trial name
- NCT04093726
- Testing
- lollipop
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Healthy Subjects, Sleep Initiation and Maintenance Disorders
An Evaluation of Potential Next-day Residual Effects of Eszopiclone in Healthy Volunteers.
This study will explore potential next-day residual effects of a single evening dose of 3mg of the hypnotic, eszopiclone, 7.5mg of zopiclone, and placebo, in healthy adult subjects.
- Trial name
- NCT00699608
- Where
- United Kingdom
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Non Small Cell Lung Cancer, Complete Surgical Resection
Using ctDNA to Determine Therapies for Lung Cancer
This is a study to look at whether the presence of circulating tumour DNA (ctDNA) in the blood can help to predict whether giving adjuvant treatment after surgery can decrease the chance of the cancer coming back in people with…
- Conditions
- Non Small Cell Lung Cancer, Complete Surgical Resection, Circulating Tumor DNA
- Trial name
- ctDNA Lung RCT (NCT04966663)
- Testing
- Nivolumab, Pemetrexed, Gemcitabine
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- University Health Network, Toronto
Muscle Invasive Bladder Urothelial Carcinoma, Muscle-Invasive Bladder Carcinoma
Surveillance of the Genetic Signature in Circulating Tumor DNA for Guiding Adjuvant Chemotherapy in Urothelial Carcinoma
Urothelial carcinomas are one of the most commonly diagnosed cancers worldwide. Postoperative patients carry a poor prognosis with an estimated five-year disease-specific survival rate of 50%.
- Trial name
- NCT06257017
- Testing
- gemcitabine, Cisplatin
- Where
- Hong Kong
- Volunteers
- 15 people
- Sponsor
- Yung NA
Primary Peritoneal Cavity Cancer, Recurrent Ovarian Epithelial Cancer
Interleukin-12 in Treating Patients With Ovarian Epithelial Cancer or Primary Peritoneal Cancer
Phase II trial to study the effectiveness of intraperitoneal interleukin-12 in treating patients who have ovarian epithelial cancer or primary peritoneal cancer.
- Trial name
- NCT00016289
- Testing
- recombinant interleukin-12
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Cancer Institute (NCI)
hsCRP
RIR and the Impact on Clinical Outcomes in Patients Undergoing PCI
Coronary heart disease (CAD) is caused by myocardial ischemia, hypoxia or necrosis due to coronary artery stenosis, spasm or obstruction.
- Trial name
- NCT05131750
- Where
- China
- Volunteers
- 1,408 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Aggressive B-cell Lymphomas
Proof of Concept for Real-time Multicentric Monitoring of MRD by PET and ctDNA in Aggressive B-Cell Lymphomas
RT4 (REAL TIME TAILORED THERAPY) study was designed as a national, multicenter proof of concept aiming to demonstrate the technical and operational capacity of the French Connect network and the Positron Emission Tomography (PET)…
- Trial name
- RT4 (NCT07514715)
- Testing
- blood test
- Where
- 30 sites in France
- Volunteers
- 129 people
- Sponsor
- The Lymphoma Academic Research Organisation
Acute Myeloid Leukemia, de Novo Myelodysplastic Syndrome
Selinexor in Treating Patients With Intermediate- and High-Risk Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome After Transplant
This phase I trial studies the side effects and best dose of selinexor when given after stem cell transplant in treating patients with acute myeloid leukemia that is at intermediate or high risk of spreading or coming back…
- Conditions
- Acute Myeloid Leukemia, de Novo Myelodysplastic Syndrome, Myelodysplastic Syndrome, Secondary Acute Myeloid Leukemia
- Trial name
- NCT02485535
- Testing
- Laboratory Biomarker Analysis, Selinexor
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Chicago
Fasting, Pediatric ALL
Effect of NPO Time and Type of Food Intake on Preoperative Residual Gastric Content and pH
According to normal physiology, the longer fasting period allows food particles to pass stomach through small intestines to minimize intragastric content.
- Trial name
- NCT03448991
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Postpartum Women
Evaluation of Post-voiding Residual Urine: a Before-after, Post-partum Study
The primary objective of this study is to evaluate the impact of systematic catheter-drainage of urine for parturient women immediately in the delivery room on the occurrence of post-voiding urine residue.
- Trial name
- RPM-Eval (NCT02597413)
- Testing
- Catheterization
- Where
- France
- Volunteers
- 88 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Leukemia, Myelodysplastic Syndromes
Study of Gene Modified Donor T Cell Infusion in Patients With Recurrent Disease After Allogeneic Transplant
A Phase I study of BPX-501 T cell infusion in adults with recurrent or minimal residual disease (MRD) hematologic malignancies post-allogeneic transplant.
- Conditions
- Leukemia, Myelodysplastic Syndromes, Lymphoma, Multiple Myeloma
- Trial name
- NCT02477878
- Testing
- BPX-501, Rimiducid
- Where
- 5 sites in United States
- Volunteers
- 10 people
- Sponsor
- Bellicum Pharmaceuticals
Colorectal Neoplasms
Full Thickness Resection or Endoscopic Submucosal Dissection for Difficult Colorectal Lesions.
Compare the efficacy and safety of endoscopic resection a full thickness (EFTR) with Full Thickness Resection Device (FTRD) System versus endoscopic submucosal dissection (ESD) in the treatment of Laterally Spreading Tumor Non…
- Trial name
- NCT05502276
- Testing
- Endoscopic Full-Thickness Resection (EFTR), Endoscopic Submucosal Dissection (ESD)
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- University of Roma La Sapienza
Glioblastoma, IDH-wildtype, Glioblastoma
The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma
Resection of glioblastoma in or near functional brain tissue is challenging because of the proximity of important structures to the tumor site.
- Conditions
- Glioblastoma, IDH-wildtype, Glioblastoma, Glioblastoma Multiforme of Brain, Astrocytoma, Malignant
- Trial name
- RECMAP (NCT06273176)
- Testing
- Awake mapping under local anesthesia, Asleep mapping under general anesthesia, Resection under general anesthesia without mapping
- Where
- 8 sites in United States, Belgium and 3 more
- Volunteers
- 225 people
- Sponsor
- Erasmus Medical Center
Ovarian Cancer
Prognostic Value of MRD Detection in CA125 Non-sensitive Ovarian Cancer Patients
Ovarian cancer ranks third in the incidence of gynecologic malignancies, while mortality ranks first. The tumor marker CA125 is the most concerned tumor marker in the clinical monitoring prognosis of ovarian cancer, and an…
- Trial name
- NCT06182917
- Where
- China
- Volunteers
- 35 people
- Sponsor
- West China Second University Hospital
Breast Cancer
A Study of Contrast-Enhanced Mammography (CEM) Scans in People With Breast Cancer
The purpose of this study is to find out whether Contrast-Enhanced Mammography/CEM scans performed 2 minutes and 6 minutes after receiving Iohexol contrast dye can be used to identify the amount of residual disease in the breast…
- Trial name
- NCT05990478
- Testing
- Contrast-Enhanced Mammography, Breast MRI
- Sponsor
- Memorial Sloan Kettering Cancer Center
Gastric Residual Volume
Ultrasound Vs. Free Drainage for Gastric Volume in ICU Patients on Enteral Nutrition
This study aims to evaluate the compatibility of gastric volume (GV) measurements obtained through ultrasound with the free drainage method in intensive care patients receiving enteral nutrition under three different protocols.
- Trial name
- NCT06700759
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Ilkay Ceylan
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