Clinical trials: Residual
Pseudophakia, Myopia
Treatment of Residual Refraction Errors 6 Months After Trifocal IOL Implantation With Relex-Smile
Successful treatment of residual refraction 6 months after IOL Implantation with Relex-Smile.
- Conditions
- Pseudophakia, Myopia, Hyperopia
- Trial name
- NCT04712318
- Testing
- Relex Smile, Relex smile with fresh corneal lenticule implantation
- Where
- Kosovo
- Volunteers
- 130 people
- Sponsor
- Eye Hospital Pristina Kosovo
Postoperative Residual Curarization
Incidence of Postoperative Residual Neuromuscular Blockade in the Era of Sugammadex
This study is a prospective observational study. A total 52 patients will be included in this study. We will observe the incidence of postoperative residual neuromuscular blockade in patients receiving sugammadex.
- Trial name
- NCT05760560
- Testing
- Sugammadex
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Seoul National University Hospital
Peripheral T Cell Lymphoma
Minimal Residual Disease in Peripheral T-cell Lymphoma
As T-cell receptor sequencing by LymphoTrack is an assay with high sensitivity that can be performed in peripheral blood, the investigators wish to evaluate the ability of this assay to predict which patients are at higher risk…
- Trial name
- NCT03297697
- Testing
- Tumor biopsy, Peripheral blood draw, Lymphotrack TCR clonality assay
- Where
- 3 sites in United States
- Volunteers
- 44 people
- Sponsor
- Washington University School of Medicine
Head and Neck Cancer
The RESCUE Study: Survival and Functional Outcomes Following Salvage Surgery for RESidual or reCurrent sqUamous cEll Carcinoma of the Head and Neck
The RESCUE study is a combined retrospective and prospective multicentre cohort study investigating the survival and functional outcomes in patients undergoing salvage surgery for recurrent, residual, and new primary head and…
- Trial name
- RESCUE (NCT05808920)
- Testing
- Molecular Analyses
- Where
- 9 sites in United Kingdom
- Volunteers
- 400 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Neuromuscular Blockade
Sugammadex-dosing in Bariatric Patients
Should the dose of sugammadex in morbid obese patients be calculated on the real body weight or the ideal body weight? The main objective of the trial is to compare in patients undergoing bariatric surgery the efficacy of…
- Trial name
- SugReBaCh-1 (NCT01570179)
- Testing
- ideal BW based sugammadex reversal of moderate block, real body weight based sugammadex reversal of moderate block, real body weight based sugammadex reversal of deep block
- Where
- 2 sites in France
- Volunteers
- 34 people
- Sponsor
- Central Hospital, Nancy, France
Multiple Myeloma
Multiple Myeloma Minimal Residual Disease
Three methods including flow cytometry, next generation sequencing and determination of circulating tumor cells will be performed at different time points in patients with previously undiagnosed multiple myeloma in order to…
- Trial name
- MMRD (NCT02627261)
- Testing
- blood samples and bone marrow aspirates will be collected
- Where
- 3 sites in France
- Volunteers
- 48 people
- Sponsor
- Hospices Civils de Lyon
Bacterial Overgrowth
Clinical Evaluation of the Residual Antimicrobial Activity
The purpose of this study is to evaluate the residual antimicrobial efficacy of one test product as defined by the difference between the number of a challenge bacterial species recovered following exposure to the test product…
- Trial name
- NCT04495920
- Testing
- CGB-S-100
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- CAGE Bio Inc.
Acute Myeloid Leukemia
Pilot Evaluation of a Microfluidic Assay to Detect Minimal Residual Disease and Predict Relapse in AML Patients
Purpose: The purpose of this trial is to investigate whether a microfluidics assay can detect trace amounts of residual leukemia and predict relapse in acute myeloid leukemia (AML) patients in remission who have undergone…
- Trial name
- NCT03488862
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Minimal Residual Disease, Immunoscore
Neoadjuvant CAPEOX Versus Upfront Surgery for Locally Advanced Colon Cancer With Elevated CEA: A Single-Center, Open-Label, Randomized Controlled Trial
The goal of this interventional clinical trial is to compare the efficacy of neoadjuvant chemotherapy versus upfront surgery in adults aged 18-70 years with stage II (high-risk)-III, non-MSI-H colon adenocarcinoma and elevated…
- Conditions
- Minimal Residual Disease, Immunoscore, Neoadjuvant Chemotherapy, Colon Cancer (Stage II &Amp; III)
- Trial name
- NCT07413146
- Testing
- ctDNA-Based Molecular Residual Disease (MRD) Monitoring and Immunoscore Assessment, Neoadjuvant Chemotherapy, Adjuvant chemotherapy
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Waldenstrom Macroglobulinemia
Non-invasive Diagnostics and Monitoring of MRD and Clonal Evolution in Waldenström's Macroglobulinemia and in IgM-MGUS
Multicenter retrospective and prospective observational study including patients with WM or IgM-MGUS evaluated at the time of diagnosis and during the disease course using highly sensitive techniques.
- Trial name
- FIL_BIOWM (NCT03521596)
- Testing
- MRD and clonal evolution
- Where
- 15 sites in Italy, Spain
- Volunteers
- 300 people
- Sponsor
- Fondazione Italiana Linfomi - ETS
Acute Lymphoblastic Leukemia
BEBT-908 Plus Chemotherapy Treatment for CR MRD-Positive MEF2D-Rearranged and Pre-B Acute Lymphoblastic Leukemia Patients
This investigator-initiated, prospective, single-arm, multicenter clinical trial aims to evaluate the efficacy and safety of BEBT-908 (a HDAC/PI3Kα inhibitor provided by BeBetter Med Inc ,Guangzhou, China) combined with…
- Trial name
- NCT07301138
- Testing
- BEBT-908, Cyclophosphamide, Vincristine
- Where
- China
- Volunteers
- 23 people
- Sponsor
- Ruijin Hospital
Adult Acute Lymphocytic Leukemia
Trial for Treatment of Adult Patients With Standard Risk Acute Lymphoblastic Leukemia With Chemotherapy and Rituximab
The study evaluates the efficacy and tolerability of an intensified induction and consolidation therapy in combination with rituximab in CD20 positive standard risk patients.
- Trial name
- NCT00199004
- Testing
- Cyclophosphamide, Dexamethasone / Prednisolone, Vincristine
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Hyperhidrosis
Hyperhidrosis, Developing a Treatment Approach Aims 1 & 2
The objective is to establish an evidence base for a hyperhidrosis treatment algorithm in amputees. This project will address a problem that has troubled Service members, Veterans, and civilians with amputations for decades…
- Trial name
- NCT03416348
- Testing
- Aluminum Chloride 20% (deodorant), Alcohol
- Where
- 2 sites in United States
- Volunteers
- 95 people
- Sponsor
- University of Utah
Breast Cancer
Postoperative Use of Zoledronic Acid in Breast Cancer Patients After Neoadjuvant Chemotherapy
The purpose of this study is to determine the event-free survival (EFS) after zoledronic acid for 5 years versus no postoperative treatment in patients with "chemo-insensitive" breast cancer (ypT1-4 and/or ypN1-3) after…
- Trial name
- NATAN (NCT00512993)
- Testing
- Zoledronic acid
- Where
- 93 sites in Austria, Germany
- Volunteers
- 654 people
- Sponsor
- GBG Forschungs GmbH
Neuromuscular Block, Residual
Evaluation of Residual Neuromuscular Blockade and of Late Recurarization in the Post Anesthesia Care Unit in Patients Undergoing Videolaparoscopic Cholecystectomy
Neuromuscular blockade is essential to provide optimal conditions for tracheal intubation and also to facilitate the performance of surgeries involving mainly the abdominal cavity.
- Trial name
- NCT03831815
- Testing
- Cisatracurium
- Where
- Brazil
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Coronary Artery Disease, Atherosclerotic Cardiovascular Disease (ASCVD)
Hs-CRP-Guided Colchicine Treatment Targets in Very-High-Risk Patients With Coronary Artery Disease After PCI (TARGET-CHD)
This multicenter, randomized, open-label, noninferiority trial will compare two high-sensitivity C-reactive protein (hs-CRP) target-guided colchicine strategies in 1,768 adults with very-high-risk coronary artery disease after…
- Conditions
- Coronary Artery Disease, Atherosclerotic Cardiovascular Disease (ASCVD), Residual Inflammatory Risk
- Trial name
- NCT07920133
- Testing
- Colchicine (Colcrys®)
- Where
- China
- Volunteers
- 1,768 people
- Sponsor
- Sir Run Run Shaw Hospital
Chronic Periodontitis
Clinical Efficacy Of 810 Nanometer Diode Laser As An Adjunct To Mechanical Periodontal Treatment Of Residual Periodontal Pockets
Background: Aim of this randomized controlled parallel-designed study was to evaluate the effects of diode laser as an adjunct to mechanical periodontal treatment on clinical parameters and gingival crevicular fluid (GCF) volume…
- Trial name
- NCT02531555
- Testing
- 810 Nanometer Wavelenght GaAlAs Diode Laser, Gracey curettes
- Where
- Turkey (Türkiye)
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Marmara University
Prostate Cancer, Neoplasm, Residual
Feasibility of the LUM Imaging System for Detection of Prostate Cancer
The primary objective of this feasibility study is to determine if administration of LUM015 will result in positive fluorescence of tumor tissue from ex vivo specimen imaging with the LUM Imaging device from patients undergoing…
- Trial name
- NCT03441464
- Testing
- LUM Imaging System
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Lumicell, Inc.
Minimal Residual Disease, Donor Lymphocyte Infusion
MRD-directed Donor Lymphocyte Infusion for Reduce of Relapse After Allo-HSCT
Allogeneic hematopoietic cell transplantation (Allo-HSCT) is an effective therapy for acute leukemia, but relapse remains an important problem.
- Conditions
- Minimal Residual Disease, Donor Lymphocyte Infusion, Hematopoietic Stem Cell Transplantation, Relapse
- Trial name
- NCT02673008
- Testing
- donor lymphocyte infusion
- Where
- China
- Volunteers
- 206 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Knee Osteoarthritis (Knee OA), Total Knee Anthroplasty
Drain Removal Before Versus After CPM in Primary Total Knee Arthroplasty
The aim of this prospective randomized controlled study was to determine whether the timing of drain removal in relation to continuous passive motion (CPM) application influences postoperative residual hematoma formation…
- Conditions
- Knee Osteoarthritis (Knee OA), Total Knee Anthroplasty, Postoperative Hematoma
- Trial name
- NCT07302724
- Testing
- Drain Removal Before CPM, Drain Removal After CPM
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Ankara Etlik City Hospital
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