Clinical trials: Residual Disease
Pre B ALL, Regulatory T Cell
The Effect of Chemotherapy on Regulatory T Cells
The investigators aimed to study the effect of chemotherapy on regulatory T cells (Tregs) in children with precursor B (PreB) acute lymphoblastic leukemia (ALL) at 15 and 33 days of malignity directed therapy.
- Trial name
- NCT03413046
- Testing
- Peripheral and bone marrow sampling
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara Children's Health and Diseases Hematology and Oncology Training and Research Hospital
Tendinopathy, Elbow
Efficiency of Kinesio Taping in Chronic Lateral Epicondylitis
Lateral epicondylitis is a degenerative tendinosis of the extensor carpi radialis brevis muscle and is the most common work/sports-related chronic musculoskeletal problem affecting the elbow.
- Trial name
- NCT04518527
- Testing
- Tape
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Elif Balevi Batur
Residual, Progressive or Recurrent Grade II or III Meningioma
NEO100 and High-Grade Meningioma
This multi-site, Phase 2 clinical trial is an open-label study to identify the safety, pharmacokinetics, and efficacy of a repeated dose regimen of NEO100 (perillyl alcohol) for the treatment of patients with residual high-grade…
- Trial name
- NCT05023018
- Testing
- NEO100
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- Neonc Technologies, Inc.
Type I Hypersensitivity
Assessment of the Contribution of Monophosphoryl Lipid A (MPL) to a Grass Pollen Allergy Vaccine
Allergen-specific immunotherapy (SIT), the administration of gradually increasing quantities of an allergen extract to an allergic patient, is a curative approach which directly treats the underlying allergic disease.
- Trial name
- NCT00133146
- Testing
- Grass MATA MPL
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- Allergy Therapeutics
Dental Diseases
Amount of Cementum After Scaling, Root Planing and Glycine Air Polishing
The purpose of this study was to evaluate the residual cementum with the histological measurements and root surface topography with SEM evaluation using four periodontal treatment methods.
- Trial name
- NCT02205619
- Testing
- Air Flow Master Piezon®, EMS SA, Nyon, Swiss, Gracey curettes, American Eagle, Missoula, MT, USA, Air-flow® Powder Perio, EMS SA, Nyon, Swiss
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Acute Coronary Syndrome, Coronary Artery Disease
Comparison of Ticagrelor Versus Clopidogrel on Residual Thrombus Burden During PCI: an OCT Study
Subjects with acute coronary syndromes scheduled for cardiac catheterization will be enrolled in this study. Subjects that are to be treated clinically with coronary artery stenting will be randomized to receive a loading dose of…
- Trial name
- NCT01826175
- Testing
- Ticagrelor, Clopidogrel, Optical Coherence Tomography
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma
Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL)
Patients with human papillomavirus (HPV)-related oropharyngeal cancer generally have favorable outcomes and how well they do depends on the specific details about the patient and their cancer.
- Conditions
- Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma, Oropharynx Cancer, Oropharynx Squamous Cell Carcinoma
- Trial name
- SAVAL (NCT06088381)
- Testing
- Experimental Observation, Observation per Standard of Care, Adjuvant Treatment per Standard of Care
- Where
- 5 sites in United States
- Volunteers
- 61 people
- Sponsor
- University of Maryland, Baltimore
Lung Neoplasms
Pulmonary Ventilation/Perfusion Imaging for the Prediction of Postoperative Residual Pulmonary Function
Lung cancer is one of the most common malignant tumors in the world and with the highest incidence in China. Surgery is the most effective therapeutic method for primary lung cancer.
- Trial name
- NCT03357094
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Beijing Tongren Hospital
Lung Cancer
MRD Monitoring in Lung Cancer After Resection
The conception of molecular residual disease (MRD) extending from hematologic tumor to solid tumors. Evidences supporting MRD evaluation for lung cancer by liquid biopsy has gradually accumulated, especially circulating tumor DNA…
- Trial name
- NCT04976296
- Testing
- MRD detection
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Guangdong Provincial People's Hospital
Urinary Tract Infection
Role of Residual Urine and Asymptomatic Prostatitis in the Development of Urinary Tract Infections in Spinal Cord Injury
The purpose of this prospective study is to investigate the association between the amount of residual urine and asymptomatic bacterial prostate infection with the occurrence of recurrent (>2 /year) symptomatic urinary tract…
- Trial name
- NCT01601041
- Testing
- sonographic assessment of residual urine, urine culture
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Enteral Feeding Intolerance, Critical Illness
Continuous Versus Intermittent Enteral Feeding and Gastric Residual Volume in Critically Ill Patients
This study will compare two commonly used methods of enteral feeding in critically ill adults: continuous feeding and intermittent feeding.
- Trial name
- NCT07876141
- Testing
- Continuous Enteral Feeding, Intermittent Enteral Feeding
- Where
- Vietnam
- Volunteers
- 76 people
- Sponsor
- Viet Duc University Hospital
Bipolar Disorder
Mindfulness-Based Cognitive Behavior Therapy for Bipolar Disorder
The purpose of the study is to investigate the efficacy of mindfulness-based cognitive-behavior therapy (MBCT) for improvement of symptoms associated with bipolar disorder, by comparing MBCT to supportive psychotherapy.
- Trial name
- MBCT (NCT01126827)
- Testing
- Mindfulness-Based Cognitive Behavioral Therapy or Supportive Psychotherapy
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Massachusetts General Hospital
Speech Sound Disorder
Comparing Traditional and Biofeedback Telepractice Treatment for Residual Speech Errors
This study aims to evaluate the relative efficacy of biofeedback and traditional treatment for residual speech errors when both are delivered via telepractice.
- Trial name
- C-RESULTS TPT (NCT04625062)
- Testing
- Visual-acoustic biofeedback, Motor-based treatment
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- New York University
Acute Lymphoblastic Leukemia
LAL-BR/2001: Study Treatment to Low Risk ALL
The purpose of this study is increase the efficacy of consolidation (C1) after an intensification phase with high dose of methotrexate, applying analysis of minimal residual disease
- Trial name
- NCT00526175
- Testing
- Prednisone, Vincristine, Daunorubicin
- Where
- 25 sites in Spain
- Volunteers
- 150 people
- Sponsor
- PETHEMA Foundation
Small Cell Lung Carcinoma
Exploration of Treatment Strategies After Concurrent Chemoradiotherapy for LS-SCLC Guided by MRD
This study plans to enroll limited-stage small cell lung cancer (LS-SCLC) patients who have achieved disease control after concurrent chemoradiotherapy (cCRT).
- Trial name
- NCT07357532
- Testing
- Adebrelimab Injection, Apatinib Mesylate Tablets
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Peking University Cancer Hospital & Institute
Pulmonary Embolism
Macitentan to Prevent PRVO
About half of patients who suffer of a pulmonary embolism (blood clots in the lungs), do not clear completely the clots overtime, increasing the risk of having a new blood clot in the lungs and elevated blood pressure in the…
- Trial name
- MAC-PRO (NCT05946811)
- Testing
- Macitentan 10mg
- Where
- United States
- Sponsor
- University of Maryland, Baltimore
Tinnitus
The Longer, the Better? Investigating the Effect of Prolonged Acoustic Stimulation on Brief Acoustic Tinnitus Suppression
This study compared tinnitus suppression after 3-minute and 20-minute acoustic stimulation using an individually optimized stimulus. In total 45 tinnitus patients participated.
- Trial name
- NCT07472257
- Testing
- Acoustic Stimulation - 20 minutes, Acoustic stimulation - 3 minutes
- Where
- Germany
- Volunteers
- 45 people
- Sponsor
- University of Regensburg
Bladder Cancer, Non Muscle Invasive Bladder Cancer
Predictors of Residual Tumor at Second Transurethral Resection for pT1 Non-muscle Invasive Bladder Cancer
The START study is a multicentre retrospective project. The aim is to identify clinico-pathological predictors of residual tumor at time of second transurethral resection of bladder tumor (re-TURBt) and to identify well-selected…
- Trial name
- START (NCT06205277)
- Testing
- Second TURBt
- Where
- Italy
- Volunteers
- 1,300 people
- Sponsor
- University of Trieste
Obstructive Sleep Apnea, Sleep Hypopnea
Armodafinil (CEP-10953) in Treatment of Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea (OSA/H) Syndrome
The primary objective of this study is to determine whether treatment with Armodafinil (CEP-10953) is more effective than placebo treatment for patients with residual excessive sleepiness associated with obstructive sleep…
- Trial name
- NCT00079677
- Testing
- Armodafinil 150 mg/day
- Volunteers
- 263 people
- Sponsor
- Cephalon
Obesity, Gastric Ultrasound
Correlation of Preoperative Gastric Residual Volume With Body Mass Index and Aspiration Risk in Laparoscopic Bariatric Surgery
Obesity is a chronic, complex disease defined by the World Health Organization (WHO) as the excessive accumulation of fat in the body that can harm health.
- Conditions
- Obesity, Gastric Ultrasound, Gastric Residual Volume, Body Mass Index (BMI)
- Trial name
- NCT07032207
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
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