Clinical trials: Resistance Exercise
Lower-Limb Strength, Muscular Endurance
Study of 15% Versus 30% Velocity Loss Thresholds During Bodyweight Squats and Their Effects on Strength and Endurance in Young Women
The goal of this clinical trial is to learn how two different velocity loss thresholds (15% and 30%) during bodyweight squats affect strength and endurance in non-athletic young women aged 18-25 years.
- Conditions
- Lower-Limb Strength, Muscular Endurance, Velocity-Based Resistance Training
- Trial name
- NCT07461701
- Testing
- Body-weight squat training (15% velocity loss threshold), Body-weight squat training (30% velocity loss threshold)
- Where
- Pakistan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Health Sciences Lahore
Mobility
Best Function of Range of Motion (cRCT)
Mobility is a crucial factor for independence and quality of life in older people. However, the majority of those in retirement homes are not physically active to maintain mobility and independence.
- Trial name
- bestform (NCT04207307)
- Testing
- Multimodal exercise program, Usual Care
- Where
- Germany
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Sedentary, Cardiometabolic Syndrome
Effect of Interrupting Sedentary Time With Different Frequencies of Physical Activity on Cardiometabolic Risk Factors
The knowledge gap on sedentary behavior and sedentary breaks includes whether detrimental effects of sedentary behavior can be fully attenuated by 1.) sedentary breaks 2.) physical activity or 3.) both combined.
- Conditions
- Sedentary, Cardiometabolic Syndrome, Physical Activity
- Trial name
- NCT05622006
- Testing
- Sedentary breaks
- Where
- Norway
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Muscle Fatigue Caused by Repetitive Muscle Exercise
The Perceived Point of Muscular Discomfort vs the Point of Failure in the Ageing Population- a Pilot Study
This is an investigation into the differences in muscle activation and numerical difference in reps between the feeling of moderate discomfort and technical failure during a set of bodyweight resistance exercise.
- Trial name
- NCT07410299
- Testing
- Resistance Exercise Protocol
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Lancaster University
Blood Pressure, Hemodynamic Response
Ischemic Preconditioning in Resistance Exercise in Older Women
This study investigates whether ischemic preconditioning (IPC) can reduce cardiac demand after resistance exercise in older women.
- Conditions
- Blood Pressure, Hemodynamic Response, Rating of Perceived Exertion, Heart Rate
- Trial name
- NCT07497659
- Testing
- Ischemic Preconditioning
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Triangulo Mineiro
Knee Osteoarthritis
The Effect Of Pulsed Electromagnetic Field And Progressive Resistance Exercise On Knee Osteoarthritis
The purpose of this study is to investigate the effect of pulsed electromagnetic field and progressive resistance exercise on Knee Osteoarthritis.
- Trial name
- NCT04106986
- Testing
- Pulsed electromagnetic field and Progressives resistance exercise, PRE
- Where
- Jordan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Meniscus Tear
The Effect of Therapeutic Exercise on Cartilage Morphology and Physical Function for Individuals at High Risk of Knee Osteoarthritis
This randomized controlled trial aims to evaluate the efficacy of progressive resistance exercises (PRE) versus aerobic exercises on cartilage morphology and physical function in patients with degenerative meniscus tears.
- Trial name
- NCT06532851
- Testing
- Progressive Resistance Exercise (PRE), Aerobic Exercise, Control
- Where
- 2 sites in Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Insulin Sensitivity
Physical Activity and Insulin Sensitivity Dynamics
The study investigates the role of one single bout of exercise in mediating enhancement of muscle insulin sensitivity following a single bout of exercise.
- Trial name
- NCT06776094
- Testing
- One-legged-knee extensor exercise, Insulin infusion, Muscle Biopsy Medication: Lidocaine
- Where
- Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Cigarette Smoking, Coronary Heart Disease
Exercise and Coronary Heart Disease Risk Markers in Male Smokers and Non-Smokers
The present study will investigate the effect of acute exercise on fasting and postprandial risk markers for coronary heart disease (CHD) in healthy male cigarette smokers and non-smokers.
- Conditions
- Cigarette Smoking, Coronary Heart Disease, Cardiovascular Risk Factor, Insulin Resistance
- Trial name
- NCT03735186
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Inflammation, Sarcopenia
The Combined Effects of Resistance Training and Flax Oil Supplementation Upon Inflammation in Older Adults
Loss of muscle mass and functional ability is a major concern for older individuals. Aging is associated with increased inflammation caused by release of hormone-like compounds termed "cytokines" which are involved in muscle…
- Trial name
- NCT00465153
- Testing
- flax oil containing alpha linolenic acid, Resistance exercise training
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Disorders, Substance Related
A Study on the Effects of Breathing Exercises and Aerobic Exercise on the Health of Men in Drug Rehabilitation
This study aims to investigate the effects of an 8-week combined exercise program on male individuals in drug rehabilitation. The program integrates resistance-based breathing training with aerobic exercise.
- Trial name
- NCT07592195
- Testing
- Resistance Breathing Training, Aerobic Exercise
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Southwest Medical University
Sarcopenia
Older Adult Training Study With Creatine and CLA
We examined whether creatine monohydrate (CrM) and conjugated linoleic acid (CLA) could enhance strength gains and improve body composition (i.e., increase fat-free mass (FFM); decrease body fat) following resistance exercise…
- Trial name
- OTR (NCT00473902)
- Testing
- Training, Creatine Monohydrate, Conjugated Linoleic Acid
- Where
- Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Sedentary Behavior, Aging
Oral 'Breath Test' to Measure Anabolic Sensitivity in Young and Older Adults at Different Activity Levels
Recent work in the investigators laboratory has examined the ability of a non-invasive 13CO2 breath-test to assess differences in amino acid oxidation rates and net balance in young healthy males following protein feeding and…
- Conditions
- Sedentary Behavior, Aging, Sarcopenia, Amino Acids
- Trial name
- ARBT (NCT05216809)
- Testing
- Habitual Physical Activity, Step-Reduction
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Sarcopenia, Dietary Protein
Dietary Protein Quality for Skeletal Muscle Anabolism in Older Adults
Dietary proteins potently augment muscle protein synthesis. Because of poorer anabolic sensitivity with ageing, studies and guidelines recommend higher dietary protein intake for older adults.
- Conditions
- Sarcopenia, Dietary Protein, Resistance Exercise
- Trial name
- NCT05574205
- Testing
- Resistance Exercise, Protein supplementation
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Aged, 80 and Over, Resistance Training
Resistance-type Exercise Training in the Older Population
Background: Aging is associated with muscle mass and strength loss and "oldest" old people (≥85 y) are at a far greater risk of developing sarcopenia.
- Trial name
- RETO (NCT04999501)
- Testing
- Prolonged resistance-type exercise training
- Where
- Chile
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Insulin Resistance Syndrome
Aerobic and Strength Training With Caloric Restriction on Insulin Resistance in Obese Premenopausal Women
A total of 42 premenopausal women diagnosed clinically as having insulin resistance. Their ages ranged from 35 to 45 years old; their body mass index was >30 kg/m2 and They were obese women complained of insulin resistance and…
- Trial name
- NCT03716336
- Testing
- Resistance exercise, Aerobic exercise, diet restriction
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Motor Activity, Body Weight
Effects of Aerobic Exercise Detraining
The proposed study seeks to better understand the role of body weight, energy expenditure, and energy intake as mechanisms of body weight gain during detraining following aerobic exercise.
- Conditions
- Motor Activity, Body Weight, Obesity
- Trial name
- E-Mechanic_Fol (NCT02158130)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Metabolic Syndrome X, Insulin Resistance
Physical Inactivity and Insulin Resistance in Skeletal Muscle.
The purpose of this study is to determine how a decline in physical activity acutely leads to a decrease in insulin sensitivity in skeletal muscle.
- Conditions
- Metabolic Syndrome X, Insulin Resistance, Hypertension, Hypercholesterolemia
- Trial name
- NCT00536211
- Testing
- Exercise, Metformin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Multiple Sclerosis
EFFECTS OF AEROBIC AND RESISTANCE TRAINING ON IMMUNE FUNCTION IN MULTIPLE SCLEROSIS
Background: Multiple Sclerosis (MS) is a chronic immune-mediated, inflammatory, and neurodegenerative central nervous system disorder characterized by axonal damage.
- Trial name
- ABIF-MS (NCT07640100)
- Testing
- Aerobic and Progressive Resistance Exercise Program, Standard Care (in control arm)
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Seda Saka
Inflammation, Insulin Sensitivity
Exercise and Inflammation in the Elderly
Persistent low-grade inflammation and impaired fibrinolysis, are independent predictors of several chronic diseases highly prevalent in the older Veteran population including cardiovascular disease (CVD), stroke, and diabetes.
- Trial name
- IRIS (NCT00753363)
- Testing
- Weight Loss, Aerobic Exercise Training
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development