Clinical trials: Resistant Depression, Treatment
Adolescent Depression
Repetitive Transcranial Stimulation (rTMS) for Resistant Depression in Adolescents
The investigators hypothesis that repetitive transcranial Stimulation (rTMS) is a safe and effective add-on therapy for resistent depression in adolescent patients.
- Trial name
- NCT01170520
- Testing
- repetitive transcranial Stimulation
- Where
- 2 sites in Israel
- Volunteers
- 24 people
- Sponsor
- Shalvata Mental Health Center
Depressive Disorder, Major
A Naturalistic Study of the Efficacy and Safety of Escitalopram in Treatment Resistant Depression
The primary objective of this multicenter study is to evaluate the efficacy of escitalopram in treatment resistant depression (TRD), assessed by 2 consecutive failed antidepressant treatments from different classes.
- Trial name
- NCT00220480
- Testing
- escitalopram
- Where
- 4 sites in Israel
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center
Depressive Disorder
Acute Efficacy and 6 Months Follow up After Electroconvulsive Therapy
The overall aim of the current project is to assess the acute and long term outcome of ECT (both patient and clinician rated) in a non-selected patient cohort from ordinary clinical activity, and to seek out factors predicting…
- Trial name
- NCT05388461
- Testing
- electroconvulsive therapy
- Where
- 2 sites in Norway
- Volunteers
- 600 people
- Sponsor
- Haukeland University Hospital
Electroconvulsive Therapy, Intravenous Ketamine
Electroconvulsive Therapy Versus Intravenous Ketamine in Treatment-Resistant Major Depressive Disorder
This study aimed to compare the efficacy, safety, and tolerability of electroconvulsive therapy (ECT) versus intravenous (IV) ketamine in adults with treatment-resistant major depressive disorder (TRD).
- Conditions
- Electroconvulsive Therapy, Intravenous Ketamine, Treatment-Resistant, Major Depressive Disorder
- Trial name
- NCT07526454
- Testing
- Electroconvulsive Therapy, Ketamine
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Depressive Disorder, Major Depressive Disorder
Nitrous Oxide for Major Depressive Disorder
This study aims at investigating the persistence of antidepressant effect of Nitrous Oxide (N2O) for Treatment-Resistant Depression(TRD).
- Conditions
- Depressive Disorder, Major Depressive Disorder, Treatment Resistant Depression, Depressive Disorder, Major
- Trial name
- NCT03932825
- Testing
- Nitrous Oxide
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Lingjiang Li
Treatment Resistant Depression
Psilocybin Versus Ketamine in Treatment-Resistant Depression
The main goal is to compare the antidepressant effects of psilocybin and ketamine in patients with TRD versus the antidepressant inactive substance midazolam.
- Trial name
- PSIKET_001 (NCT05383313)
- Testing
- Psilocybin, Ketamine Hydrochloride, Midazolam Ph. Eur 9.0
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- National Institute of Mental Health, Czech Republic
Severe Permanent Uni or Bilateral Non-pulsatile Tinnitus, Without Associated Vestibular Pathology
Evaluation of Deep Brain Stimulation (DBS) of the Right Operculum 3 (OP3) in Permanent Non-pulsatile Disabling Tinnitus (TINNOP3-DBS)
This pilot study aims at evaluating the effectiveness of the treatment of unilateral or bilateral, non-pulsatile, disabling, tinnitus, without vestibular dysfunction, using Deep Brain Stimulation (DBS) of the parieto-insular…
- Conditions
- Severe Permanent Uni or Bilateral Non-pulsatile Tinnitus, Without Associated Vestibular Pathology, Resistant to Therapeutic Failure, With or Without Hearing Loss
- Trial name
- TINNOP3-DBS (NCT04296097)
- Testing
- DBS
- Where
- France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Grenoble
Treatment Resistant Depression (TRD)
Ketamine Treatment for Treatment-Resistant Depression - the Role of Framing
Ketamine is a medicine used in psychiatry for treatment-resistant depression. This study compares two ways of framing ketamine treatment: a psychedelic framing and a biomedical framing.
- Trial name
- KetSet (NCT07824973)
- Testing
- Psychedelic framing, Biomedical framing
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Valdemar Landgren