Clinical trials: Resolution
Urinary Catheterization
A Study Evaluating a Urinary Catheter With Different Activation Times for the Wetting Solution, in Healthy Male Volunteers.
The primary purpose of this study is to compare the subject's perception (separately for each randomized catheter) of practicing catheterization when using catheters with sodium chloride in wetting solution (using two different…
- Trial name
- NCT00748033
- Testing
- Reference catheter: LoFric PVC, Nelaton 40 cm, CH 12, LoFric POBE Hydro-Kit II, 5 seconds, LoFric POBE Hydro-Kit II, 24 hours
- Where
- Sweden
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Wellspect HealthCare
Cognitive Change
Digital Solution to Improve Cognitive Function in Epilepsy: PRODDIGE Project
Background: Epilepsy leads to cognitive impairment in 20-50%. Compared to seizures, these cognitive disorders are a major additional factor in occupational, social and family disability.
- Trial name
- PRODDIGE (NCT05057156)
- Testing
- cognitive rehabilitation
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Healthy
Safety, Tolerability and Pharmacokinetics of BI 34021 FU2 Oral Drinking Solution in Healthy Male Volunteers
Evaluation of safety, tolerability and PK of single rising oral doses of BI 34021 FU2 in healthy male volunteers; comparison of 100 mg drinking solution vs. tablet, assessment of food effect by re-dosing at 50 mg and 150 mg
- Trial name
- NCT02259842
- Testing
- BI 34021 FU2 solution, BI 34021 FU2 tablet, High fat, high calorie breakfast
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Smoking Cessation
A Study Evaluating The Absorption Of Varenicline Into The Body From A Varenicline Solution And A Varenicline Patch Applied To The Skin
To evaluate the absorption, safety, and tolerability of a varenicline solution and a varenicline patch applied to the skin.
- Trial name
- NCT00774605
- Testing
- Varenicline free base solution, Varenicline free base patch
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Gingivitis
Atlas of Experimental Gingivitis in Humans
Pilot case series with a split-mouth design to track subjects with known exposure (dental biofilm accumulation) over 21 days. Descriptive design, using single cell RNA sequencing as a "digital biopsy" to catalog and contrast…
- Trial name
- ATL (NCT04105569)
- Testing
- Stent-Induced Biofilm Overgrowth
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Healthy Subjects
Normative Metrics of High-Resolution Anorectal Manometry With the Use of Water-perfused System in a Healthy Russian Cohort
High resolution anorectal manometry (HRAM) normative values are still need to be studied in different populations and with the use of different (solid-state and water-perfused) systems.
- Trial name
- NCT03897296
- Testing
- High resolution anorectal manometry, water perfused catheter
- Where
- 2 sites in Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Russian Academy of Medical Sciences
Post Procedural Pain Management in Neonates
Comparison of Minimal Effective Dose of Sucrose for Pain Relief in Neonates After Minor Procedure
Type of Study: Randomized Controlled Trial Aim: To compare the effectiveness of two doses of sucrose solution for pain relief in neonates after minor procedures.
- Trial name
- NCT06446323
- Testing
- 0.2 ml dose of sucrose
- Where
- Pakistan
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Healthy Adults
3T Magnetic Resonance Neurography
The goal of this observational study is to evaluate whether optimized high-resolution MRI can better visualize very fine nerves in the cervical spine and neck region compared to standard MRI.
- Trial name
- 3T MRN (NCT07513467)
- Testing
- High-resolution three-dimensional magnetic resonance neurography protocols
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Asthma
GSK2190915A - Bioavailability Study
GSK2190915 is a high affinity 5-lipoxygenase-activating protein (FLAP) inhibitor that reduces inflammation in cells. This study will evaluate three capsule and two tablet formulations to select the optimal formulation for further…
- Trial name
- NCT02224521
- Testing
- GSK2190915 Solution., GSK2190915 Granule Capsule (A), GSK2190915 Semi-solid Lipid Capsule (B)
- Where
- United Kingdom
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cotinine Levels, Arterial Aneurysm Wall Enhancement on HRMRI
A Study on the Correlation Between Cotinine Levels and Aneurysm Wall Enhancement on HRMRI.
This study aims to collect clinical, laboratory, and imaging data from patients with unruptured intracranial aneurysms, and collect blood or urine samples for cotinine testing.
- Trial name
- NCT06447714
- Testing
- smoke
- Where
- China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Healhty
Pharmacokinetics of Huperzine A Oral Solution in Healthy Participants
In this study, 4 dose groups are planned: Group 1 (0.22 mg, QD), Group 2 (0.22 mg, BID), Group 3 (0.44 mg, QD), and Group 4 (0.44 mg, BID).
- Trial name
- NCT07784335
- Testing
- Huperzine A Oral Solution
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wanbangde Pharmaceutical Group Co., LTD
Molluscum Contagiosum
Comparison of 5% Potassium Hydroxide With 10% Potassium Hydroxide Solution in Treatment of Molluscum Contagiosum
Molluscum is a virus-related skin infestation which is commonly seen among children. Molluscipox virus, the largest human virus, causes it.
- Trial name
- NCT05634460
- Testing
- potassium hydroxide
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Combined Military Hospital Abbottabad
Diabetic Macular Edema
OCT-angiography in Diabetic Patients
Around the world there is an increasing incidence of diabetes mellitus, with millions of people affected. In this population, diabetic macular edema (DME) is the most common cause of visual impairment.
- Trial name
- NCT02870803
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Retina Clinic, Sao Paulo, Brazil
Pressor Response, Baroreflex Sensitivity
High Resolution Phenotyping in Healthy Humans
Baroreflex sensitivity is integral to blood pressure regulation, and varies among healthy, normotensive individuals. A reduced compensatory ability of baroreflex buffering in patients with carotid denervation results in blood…
- Conditions
- Pressor Response, Baroreflex Sensitivity, Blood Pressure Variability, Heart Rate Variability
- Trial name
- NCT00943774
- Testing
- Physiological maneuvers
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Healthy
A Study Comparing PF-06273340 Immediate Release Tablet, PF-06273340 Modified Release Tablets To PF-06273340 Oral Solution In The Fasted State. This Study Will Also Compare PF-06273340 Modified Release Tablets In Fasted And Fed State
The primary purpose of this study is to estimate the relative bioavailability and food effect of PF-06273340 tablets.
- Trial name
- NCT01706796
- Testing
- PF-06273340
- Where
- Singapore
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Acne, Alopecia
To Evaluate the Safety, Tolerability and PK of GT20029 Gel and Solution in Healthy Subjects
The study is a randomized, double-blind, vehicle-controlled, parallel group, phase 1 study to evaluate the Safety, Tolerability and PK of GT20029 in healthy subjects
- Trial name
- NCT06468579
- Testing
- GT20029
- Where
- China
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Suzhou Kintor Pharmaceutical Inc,
Healthy Subjects
Measurement of HTL0016878 in Cerebrospinal Fluid
A Phase 1, open-label, randomised, single oral dose study to determine the concentration of HTL0016878 in CSF and plasma in healthy male subjects following dosing with HTL0016878 10 mg or 20 mg oral solution
- Trial name
- NCT04849286
- Testing
- HTL0016878
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Nxera Pharma UK Limited
Aphasia
The Usage of High-resolution Magnetic Resonance Imaging in Patients With Post-stroke Aphasia for Predicting the Outcome
Combined analysis of functional and structural language network changes may be a good model for predicting language outcome.
- Trial name
- NCT03475745
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Bioavailability
Oxandrolone in Healthy Adults: A Relative Bioavailability Study
To assess the pharmacokinetics and relative bioavailability of a single dose of approximately 0.1 mg/kg of a medium chain triglyceride (MCT) oil oxandrolone solution vs. tablets in a small cohort of healthy adults.
- Trial name
- NCT03218631
- Testing
- Oxandrin
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Utah
Wound Infection, Complication, Postoperative
Chlorhexidine Gluconate vs Povidone-Iodine Vaginal Cleansing Solution Prior to Cesarean Delivery
Endometritis, an infection of the uterus in the postpartum period, has been shown to complicate the postoperative course of a cesarean delivery in 6% to 27% of cases.
- Trial name
- NCT02915289
- Testing
- Povidone Iodine, Chlorhexidine gluconate
- Where
- United States
- Volunteers
- 1,114 people, healthy volunteers welcome
- Sponsor
- Richmond University Medical Center
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