Clinical trials: Resolution
Colonoscopy
Comparison of Different Low Volume Solutions Prior to Colonoscopy
Study evaluates the head -to-head efficacy and tolerability of low volume preparations prior to colonoscopy
- Trial name
- NCT03698474
- Testing
- Natrium picosulfate / Magnesium citrate, Polyethylene glycol / Ascorbic acid, Natrium/ Kalium/ Magnesium sulfate
- Where
- Czechia
- Volunteers
- 612 people, healthy volunteers welcome
- Sponsor
- Tomas Bata Hospital, Czech Republic
Idiopathic Pulmonary Fibrosis
Study of ARO-MMP7 Inhalation Solution in Healthy Participants and Participants With Idiopathic Pulmonary Fibrosis
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of ARO-MMP7 in normal healthy volunteers (NHVs) and in participants with idiopathic pulmonary fibrosis (IPF).
- Trial name
- NCT05537025
- Testing
- ARO-MMP7 Inhalation Solution
- Where
- 19 sites in Denmark, Italy and 4 more
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Arrowhead Pharmaceuticals
Pregnancy Tests
Resolution of Uncertainty Through Testing
Given the high rate of delayed adoption of antenatal care (ANC), and high rates of unintended pregnancy and unsafe abortion in Uganda, research on the period of time before confirmation of pregnancy is critical to understand…
- Trial name
- NCT03179059
- Testing
- Pregnancy test at Baseline, Pregnancy test at follow up survey
- Where
- Uganda
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Diabetes
Appropriation of the Connected Solution Freestyle Libre® in Adult Patients With Diabetes in the Context of Therapeutic Education
Following the proposal to self-monitor by the Freestyle Libre® (FSL) connected object, in diabetic patients in the context of therapeutic education, regarding the appropriation of FSL, what works, for which patients , in what…
- Trial name
- APPRO-FSL (NCT04739124)
- Testing
- Follow-up questionnaires, Interviews
- Where
- 2 sites in France
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Gastroesophageal Reflux Disease
The Effect of High PCO2 Solution on Esophageal Acid Sensation
To determine the effect of intraesophageal high PCO2 solution as compared to acidic and saline solutions on subjects' heartburn sensation using stiumlus-response functions.
- Trial name
- PC02 (NCT01128608)
- Testing
- 24-Hr Esohpageal pH Monitoring, PCO2 Acid Perfusion and 0.1N HCI Perfusion
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Southern Arizona VA Health Care System
Dilatation of Cranial Arteries; MMA, STA and MCA, Headache
The Effect of Levcromakalim Infusion on the Cranial Arteries Over Several Hours Using a High Resolution MRA Technique in a Randomized, Double-blind Placebo-controlled Design in Healthy Volunteers.
Healthy participants vill randomly be allocated in a 2:1 order to receive 1 mg levcromakalim or placebo (isotonic saline) for 20 min.
- Trial name
- NCT03609008
- Testing
- Levcromakalim, Saline
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Arrhythmias, Cardiac
Artificial Intelligence (AI) Enabled, Cloud-based ECG Diagnostic Solution (ZBPro) Feasibility Testing
The proposed research is to address the accessibility and affordability of technology to capture symptomatic and asymptomatic cardiac events via Long-Term Continuous Electrocardiogram Monitoring (LTCM), and to provide physicians…
- Trial name
- NCT06013917
- Testing
- Cardiac Monitoring
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- ZBeats INC
Schizophrenia
Normal and Abnormal ERP During ToM and Emotional Conflicts in Schizophrenia
Case-control comparison of clinical population, interventional and single-center research.
- Trial name
- SERC (NCT02896374)
- Testing
- Theory of mind without visual cues
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Versailles Hospital
Cathartic Colon
Oral Sulfate Solution (SUPREP) Versus Polyethylene Glycol (PEG) Plus Ascorbic Acid
The aims of the present study is to compare oral sulfate solution (OSS) with low-dose polyethylene glycol plus ascorbic acid (2-L PEG/Asc) for bowel cleansing efficacy.
- Trial name
- NCT02761213
- Testing
- Oral sulfate solution (OSS), 2-L PEG/Asc
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bo-In Lee
ADME
Mass Balance Study of [14C]Xeruborbactam (QPX7728) in Healthy Adult Male Participants
This is a single-dose, phase 1 open-label study to determine the mass balance recovery and metabolic profiling and identification for intravenous (IV) administered [14C]xeruborbactam.
- Trial name
- NCT07083817
- Testing
- [14C]Xeruborbactam
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Qpex Biopharma, Inc.
Healthy
Pharmacokinetic Study of JNJ-42756493 in Healthy Participants
The purpose of this study is to evaluate the absolute bioavailability (the extent to which a drug or other substance becomes available to the body) of JNJ-42756493 following a single 10 milligram (mg) dose as an oral solution…
- Trial name
- NCT02218073
- Testing
- JNJ-42756493 10 mg tablet, JNJ-42756493 10 mg Oral Solution, JNJ-61818549
- Where
- Belgium
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Healthy Participants
A Study of Effect of Deodorant and Axillary Hair on Testosterone Absorption in Healthy Participants
This study will evaluate the effect of deodorant and antiperspirant use and the presence of underarm hair on the absorption of testosterone.
- Trial name
- NCT01725451
- Testing
- Testosterone, Deodorant Spray, Deodorant and Antiperspirant Combination Spray
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Nocturnal Enuresis
Effect of Use of DryNites Absorbent Pants on the Rate of Spontaneous Resolution of Paediatric Nocturnal Enuresis (NE)
Children vary in the age at which they achieve night-time dryness; in almost all cases children will stop bed-wetting without any need for treatment.
- Trial name
- NCT04620356
- Testing
- DryNites Pyjama Pants
- Where
- 2 sites in United Kingdom
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Kimberly-Clark Corporation
Zinc Deficiency
Effects of Liquid Zinc Supplementation and Dispersible Zinc Tablets on Plasma Zinc Concentration
The study aims to compare the effects of two different formulations of zinc supplements on plasma zinc concentrations among young Burkinabe children.
- Trial name
- NCT00944853
- Testing
- Liquid zinc syrup, Zinc tablet
- Where
- Burkina Faso
- Volunteers
- 462 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Healthy Volunteers
Pharmacokinetics of VVN461 Ophthalmic Solution
This is a single-center, double-masked, randomized, vehicle-controlled study conducted in China in adult healthy subjects
- Trial name
- NCT06906198
- Testing
- VVN461 Ophthalmic Solution 1.0%, VVN461 Ophthalmic Solution 0.5%, VVN461 Ophthalmic Solution 0.25%
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- VivaVision Biotech, Inc
Parkinson's Disease
A Sequential Two-Part, Open-Label Study in Healthy Male and Female Subjects
An Open-Label Study in Healthy Male and Female Subjects to Identify the Concentration that Provides Optimal Bioavailability of Levodopa Infused Subcutaneously via a Pump System; and to Compare the Bioavailability of…
- Trial name
- NCT02604914
- Testing
- ND0612, LCIG
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- NeuroDerm Ltd.
Acne
Phase 1/2 Sequentially Staged Safety Study in Healthy Subjects and Subjects With Mild Acne
The purpose of this study is to determine the safety of photodynamic therapy (PDT) with lemuteporfin topical solution (LTS) in healthy subjects and subjects with mild acne.
- Trial name
- NCT01490736
- Testing
- Lemuteporfin
- Where
- Canada
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Dermira, Inc.
Blood Donors
Evaluation of Whole Blood With CPD Anticoagulant and AS-7/SOLX Additive Solution
This study will evaluate a new blood collection and filtration system that is intended to be used to collect, filter, separate and store red blood cells and, separately, plasma.
- Trial name
- NCT02145507
- Testing
- SOLX (Investigational), AS-3 (Control)
- Where
- 2 sites in United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Haemonetics Corporation
Healthy Volunteers
Transient Lower Esophageal Sphincter Relaxations and High Resolution Manometry
Transient lower esophageal sphincter relaxations (tLESr) are the main mechanism of gastro-oesophageal reflux disease. They occur without any deglutition in patients but also in healthy volunteers. They are induced by meal.
- Trial name
- NCT00931593
- Testing
- Esophageal high resolution manometry associated or not with manometry with perfused Dentsleeve probe (as determined by randomization)
- Where
- 3 sites in France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Dry Eye
Tobramycin Tear Concentrations
To evaluate the Tobramycin tear concentration values of TOBRADEX® Ophthalmic Suspension, Tobramycin 0.3% / Dexamethasone 0.05% Ophthalmic Suspension versus TOBREX® Ophthalmic Solution in normal volunteers.
- Trial name
- NCT00695435
- Testing
- TOBRADEX Ophthalmic Suspension, Tobramycin 0.3% / Dexamethasone 0.05% Ophthalmic Suspension, TOBREX Ophthalmic Solution
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Alcon Research
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.