Clinical trials: Resolution
Stargardts, Retinitis Pigmentosa
High Resolution Retinal Imaging
Studying the morphology and function of the normal and diseased retina in vivo is needed for advancing the detection, diagnosis, and treatment of retinal disease.
- Conditions
- Stargardts, Retinitis Pigmentosa, Age-related Macular Degeneration, Choroideremia
- Trial name
- AOSLO (NCT01866371)
- Testing
- Retinal imaging
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Healthy
Propolis-Based Solution Application in Extraction Socket Healing
This pilot study evaluated whether a propolis-based topical solution improves soft-tissue healing after tooth extraction. Thirteen patients requiring extraction of two comparable teeth on opposite sides of the mouth were enrolled…
- Trial name
- NCT07665814
- Testing
- Propolis-based topical solution (52% propolis extract, clove oil [Eugenia caryophyllus], and white willow bark [Salix alba] extract), Saline rinse (control)
- Where
- Lebanon
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Health Adults
Sodium Bicarbonate Solution Enhances Lens Cleanliness in Magnetically Controlled Capsule Endoscopy
Magnetically controlled capsule endoscopy (MCE) is a noninvasive alternative to conventional gastroscopy with comparable diagnostic accuracy.
- Trial name
- NCT07877506
- Testing
- Sodium Bicarbonate Solution
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Healthy
Study Evaluating Absorption, Distribution, Metabolism and Excretion (ADME) of Single Dose [14C]-BI 207127 in Healthy Male Volunteers
Phase 1 study to assess the pharmacokinetics and routes of elimination of a single oral dose of [14C]-BI 207127 and to characterize the metabolic profile following single dose administration.
- Trial name
- NCT01605461
- Testing
- BI 207127 NA
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Safety, Pharmacodynamics, and Pharmacokinetics of BIBT 1011 BS in Healthy Subjects
A study to assess safety, pharmacokinetics and the effect of BIBT 986 BS, given as BIBT 1011 BS, on coagulation parameters.
- Trial name
- NCT02182037
- Testing
- Single rising doses of BIBT 1011 BS
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Contact Lens Solutions
Evaluation of a Multi-Purpose Solution
This study evaluates a multi-purpose solution when used on a daily wear basis by currently adapted soft contact lens wearers.
- Trial name
- NCT00710879
- Testing
- Bausch & Lomb Multi-Purpose Solution
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Muscular Injury
Almond Supplementation and Exercise Recovery
The PURPOSE of this study is to see if eating almonds for four weeks will reduce muscle damage, soreness, and inflammation during several days of recovery from eccentric exercise.
- Trial name
- NCT04958018
- Testing
- Almonds, Snack bars
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Infertility, Female
Cabergoline Before or After Oocyte Collection for Follicular Resolution
Randomized trial comparing the efficacy of two different times of administration of cabergoline in patients undergoing controlled ovarian stimulation and oocyte collection.
- Trial name
- NCT04096027
- Testing
- Cabergoline Pill
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fertility Center of Las Vegas
Peri-implant Mucositis, Peri-Implantitis
Experimental Peri-implant Mucositis on Implant Sites That Were Previously Treated With or Without Implantoplasty
This controlled clinical trial will assess clinically, immunologically, and microbiologically the healing of experimental peri-implant mucositis (PIM) lesions in implants treated previously with implantoplasty (IP) compared to…
- Trial name
- NCT06063876
- Testing
- Induction of experimental peri-implant mucositis, Resolution of experimental peri-implant mucositis
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Periapical Abscess
Resolution of Pain and Swelling After the Use of Neem Leaf Extract Compared to Chlorhexidine Gluconate as an Intracanal Irrigant During Pulpectomy
The trial is to test the resolution of pain, swelling and other signs of periapical infection and the antimicrobial efficacy when using the neem leaf extract compared to chlorhexidine as root canal irrigant in Pulpectomy…
- Trial name
- NCT02943759
- Testing
- Neem leaf extract, Chlorhexidine gluconate
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Placenta Accreta, Placenta Previa
Topical Adrenaline Versus Warm Saline Solution for Minimizing Intraperitoneal Bleeding During Caesarian Delivery for Placenta Previa / Accreta Spectrum ( PAS)
Placenta accreta spectrum (PAS), encompassing the terms placenta accreta, increta, and percreta; abnormally invasive placenta; morbidly adherent placenta; and invasive placentation, is a leading cause of life-threatening…
- Trial name
- NCT06030479
- Testing
- Topical adrenaline, Warm saline
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Cairo University
Colonoscopy
Comparison of 2L NRL994 With NaP Preparation in Colon Cleansing Prior to Colonoscopies for Colon Tumor Screening
To compare the efficacy, acceptability and safety of the new 2 liter gut cleansing solution (Moviprep) and NaP preparation in routine colon cleansing prior to tumor screening colonoscopies
- Trial name
- NCT00427089
- Testing
- Macrogol 3350 Na sulphate NaCl KCl Ascorbic Acid Na Ascorbate, Sodium Phosphate solution (NaP)
- Where
- 12 sites in Germany
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Norgine
Obesity, Appetite Disorders
Impact of a Satiating Diet in Obese Men With a Low Satiety Phenotype
The global research project was organized as a clinical process starting with an evaluation aiming at the determination of a diagnosis pertaining to the degree of satiety signal capacity.
- Trial name
- NCT03128697
- Testing
- Satiating diet, Control diet
- Where
- 2 sites in Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Laval University
Hemodynamics of Cranial Arteries, Headache
The Hemodynamics Effect of Glibenclamide on Levcromakalim Assessed by High Resolution Magnetic Resonance Angiography (MRA) Technique in a Randomized Double-blind Cross-over Placebo-controlled Study With Healthy Volunteers
To investigate the effect of levcromakalim/placebo infusion on cranial arteries after glibenclamide administration.
- Conditions
- Hemodynamics of Cranial Arteries, Headache, Cerebral Blood Flow
- Trial name
- NCT03886922
- Testing
- Levcromakalim, Saline
- Where
- 2 sites in Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Post-traumatic Stress Disorder (PTSD)
Prospective Cohort Study of Accelerated Resolution Therapy (ART) for Treatment of Military Psychological Trauma
This is a prospective cohort treatment intervention study (n=200) whereby U.S. service members and veterans with symptoms of PTSD will undergo 2-5 sessions of ART delivered by Florida licensed mental health professionals trained…
- Trial name
- NCT02030522
- Testing
- Accelerated Resolution Therapy (ART)
- Where
- 8 sites in United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Healthy
Bioavailability of BI 144807 Given Alone and in Combination With Ketoconazole in Healthy Male Volunteers
This trial investigates the influence of oral ketoconazole on the pharmacokinetics and safety of BI 144807.
- Trial name
- NCT01707940
- Testing
- Ketoconazole, BI 144807
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Metabolism and Pharmacokinetics of [14C]- BIBW 2992 MA2 in Healthy Male Volunteers
The aim of the study was to investigate the metabolism and pharmacokinetics of BIBW 2992 MA2 after a single oral dose of [14C]-radiolabelled BIBW 2992 MA2 in healthy male volunteers.
- Trial name
- NCT02171689
- Testing
- [14C]- BIBW 2992 MA2
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
A Study to Evaluate the Bioequivalence of an Oral Suspension Formulation, an Oral Solution Formulation, and the Marketed Tablet Formulation of Levofloxacin in Healthy Subjects
The primary objective of the study was to assess the bioequivalence of the oral suspension formulation, the oral solution formulation, and the marketed tablet formulation of levofloxacin, with the marketed tablet as the reference.
- Trial name
- NCT00602589
- Testing
- Levofloxacin oral suspension; Levofloxacin oral solution; and Levofloxacin marketed tablet formulations
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Wrinkles in the Nasolabial Folds
Effectiveness and Safety of YVOIRE Y-Solution 540
To Evaluate the Effectiveness and Safety of YVOIRE Y-Solution 540 versus YVOIRE volume plus in Nasolabial Folds Injection
- Trial name
- NCT04855188
- Testing
- YVOIRE Y-Solution 540, YVOIRE volume plus
- Where
- China
- Volunteers
- 394 people, healthy volunteers welcome
- Sponsor
- LG Chem
Healthy
Safety, Pharmacokinetics and Pharmacodynamics of BIRT 1696 BS in Healthy Human Subjects
The objectives are: 1. To assess safety, pharmacokinetics, and pharmacodynamics of BIRT 1696 BS in rising single doses. 2. To assess safety, pharmacokinetics, and pharmacodynamics of single dose of 100 mg BIRT 1696 BS after…
- Trial name
- NCT02254096
- Testing
- BIRT 1696 BS, Grapefruit juice (GFJ), High fat meal (HFM)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
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