Clinical trials: Resolution
Arthritis, Rheumatoid
A Study Of The Taste Of Different Oral Liquid Preparations Of CP-690,550 In Trained Adult Product Testers
This study will test the palatability of several different CP-690,550 oral preparations in trained product tester healthy volunteers.
- Trial name
- NCT01023100
- Testing
- CP 690,550 oral solutions
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy Subjects
Measurement of HTL0016878 in Cerebrospinal Fluid
A Phase 1, open-label, randomised, single oral dose study to determine the concentration of HTL0016878 in CSF and plasma in healthy male subjects following dosing with HTL0016878 10 mg or 20 mg oral solution
- Trial name
- NCT04849286
- Testing
- HTL0016878
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Nxera Pharma UK Limited
Smoking Cessation
A Study Evaluating The Absorption Of Varenicline Into The Body From A Varenicline Solution And A Varenicline Patch Applied To The Skin
To evaluate the absorption, safety, and tolerability of a varenicline solution and a varenicline patch applied to the skin.
- Trial name
- NCT00774605
- Testing
- Varenicline free base solution, Varenicline free base patch
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Inflammation
Investigation of the Distinct Mechanisms Involved in Inflammatory Resolution Between Healthy Men and Women
Important differences exist between sexes in incidence, disease patterns and outcomes in coronary artery disease that is not well understood.
- Trial name
- RESOLVE-SEX (NCT05597098)
- Testing
- Cantharidin
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
PTSD, Rape Sexual Assault
RRT for PTSD Symptoms in Survivors of Sexual Violence
Study to provide evidence of efficacy for Rapid Resolution Therapy in symptoms of PTSD, Anxiety, and Depression in survivors of sexual violence.
- Trial name
- NCT04073004
- Testing
- Rapid Resolution Therapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Healthy Volunteers
Single-Dose PK Study of an Oxycodone/Acetaminophen Solution in Healthy Subjects
A single-dose study evaluating the oral PK of an oxycodone/apap solution in healthy subjects under fasted conditions
- Trial name
- NCT02966860
- Testing
- Oral solution OC/APAP
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mallinckrodt
Necrotic Pulp
Effect of Irrigation With Antibiotic-containing Solutions on Postoperative Pain and Intra-canal Bacteria
The aim of this study is to compare the degree of postoperative pain and the antimicrobial effect in terms of bacterial count reduction after using co-amoxiclav-clindamycin solution versus MTAD and sodium hypochlorite irrigating…
- Trial name
- NCT04035070
- Testing
- co-amoxiclav-clindamycin solution, MTAD, 2.5% sodium hypochlorite
- Where
- Egypt
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Cairo University
Depression, Stress
Internet Based Psychological Support
The investigators have developed interactive, multimedia-intensive, computer-based treatment programs that include depression (Problem-Solving Therapy), stress management, and conflict management.
- Conditions
- Depression, Stress, Conflict Resolution
- Trial name
- NCT02726061
- Testing
- Internet-based psychological support
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Healthy
A Study in Healthy Men to Find Out How BI 425809 is Taken up and Handled by the Body
This trial intends to investigate the basic pharmacokinetics of BI 425809 and [14C]- radioactivity, including mass balance, excretion pathways and metabolism following a single oral dose of 25 mg BI 425809 (C-14) given to healthy…
- Trial name
- NCT03654170
- Testing
- BI 425809 mixed with [C-14] BI425809
- Where
- Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
MERS (Middle East Respiratory Syndrome), MERS
Study of Safety and Immunogenicity of BVRS-GamVac
The Middle East respiratory syndrome coronavirus (MERS-CoV) was identified in 2012 during the first Middle East respiratory syndrome (MERS) outbreak.
- Trial name
- NCT04130594
- Testing
- BVRS-GamVac
- Where
- Russia
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation
Simulation, Training
Simulations Impact on Nursing Students Conflict Resolution and Problem-Solving Skills
Scenario-based simulation training effectively enhances nursing students' core competencies, communication, teamwork, problem-solving, and decision-making skills, better preparing them for real-world experiences.
- Trial name
- NCT06592729
- Testing
- education
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Pulmonary Hypertension, Pulmonary Arterial Hypertension
Safety, Tolerability, and PK Parameters of Sodium Nitrite Inhalation Solution in Healthy Subjects
This is a four-part study of the safety, tolerability, and PK profile of sodium nitrite inhalation solution (AIR001) of ascending multiple doses (Part A) and of escalating doses with steady-state sildenafil (Part B) to healthy…
- Trial name
- NCT01409122
- Testing
- 15 mg sodium nitrite inhalation solution, 90 mg sodium nitrite inhalation solution, 45 mg sodium nitrite inhalation solution
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Aires Pharmaceuticals, Inc.
Pharmacokinetics
Formulation and Food Effect Study of AZD1386 in Healthy Volunteers
To investigate the pharmacokinetics of two oral solid formulations of AZD1386 in relation to the AZD1386 oral solution.
- Trial name
- NCT00714337
- Testing
- AZD1386
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Oral Cancer Screening
Non-invasive Methods for Oral Cancer Screening
Oral cancer is a common cancer worldwide, with approximately 250,000 new cases annually and a high mortality rate. Its major risk factors include smoking, alcohol consumption, and betel nut chewing.
- Trial name
- HRME (NCT07249437)
- Where
- Taiwan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Healthy
A Study in Healthy Men to Test How the Body Takes up and Tolerates Different Doses of BI 474121, and Whether it Makes a Difference if BI 474121 is Taken as a Tablet or a Drink.
The main objectives of this trial are to investigate safety, tolerability and pharmacokinetics (PK) of BI 474121 in healthy male subjects following oral administration of single rising doses.
- Trial name
- NCT04194645
- Testing
- BI 474121 tablet, BI 474121 oral solution
- Where
- Germany
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy Volunteer Subjects
A Study to Establish Safety and Maximum Tolerated Dose of IV Trehalose in Healthy Subjects
This will be a double-blind, randomized, placebo-controlled, single ascending dose study performed in healthy subjects. The study will include up to four escalating dose cohorts with eight (8) subjects in each cohort.
- Trial name
- NCT02725957
- Testing
- Trehalose for IV Infusion, Saline 0.9% IV
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bioblast Pharma Ltd.
BOWEL PREPARATION (BOWEL CLEANSING)
Patients Judging Bowel Preparation by Using SMARTPHONE Application
High-quality bowel preparation is a prerequisite for colonoscopy. Few studies have evaluated visual aids as a means of improving the quality of bowel preparation.
- Trial name
- BPBUSA (NCT01937819)
- Testing
- SMART arm
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Inje University
Pulmonary Disease, Chronic Obstructive
A Study to Determine the Excretion Balance and Pharmacokinetics of 14C-GSK573719
This will be a two-period, open-label study conducted at a single site. Six healthy male subjects will participate in the study to ensure at least four fully evaluable subjects.
- Trial name
- NCT01362257
- Testing
- Treatment Period 1 - IV dose of GSK573719, Treatment Period 2 - Oral dose of GSK573719
- Where
- Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Post Induction Hypotension
Dose Responsive Study of Ringer's Lactate Solution in Prevention of Post-induction Hypotension
To assess the dose responsiveness of ringer lactate solution in prevention of post-induction hypotension predicted by Ultrasound guided Inferior Vena Cava diameter in patients receiving General anesthesia.
- Trial name
- NCT05924230
- Testing
- RL 10ml/kg, RL 15ml/kg
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tata Main Hospital
Healthy Subjects
Assessment of Nasal Deposition and Clearance of Ketorolac Solution Administered Using the Valois Nasal Spray Device
This was a randomised three-way crossover design study. The study consisted of three study periods each separated by a minimum 44 hour washout period.
- Trial name
- NCT01356212
- Testing
- Ketorolac tromethamine
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Egalet Ltd
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