Clinical trials: Resolution
Age Related Macular Degeneration, Glaucoma
Prospective Study Phase: Retinal Oxygen Saturation, Blood Flow, Vascular Function and High Resolution Morphometric Imaging in the Living Human Eye
Canadians fear loss of vision more than any other disability. Vision loss has an enormous impact on quality-of-life and is extremely costly from a societal and economic perspective.
- Conditions
- Age Related Macular Degeneration, Glaucoma, Diabetic Retinopathy.
- Trial name
- NCT01348672
- Where
- Canada
- Volunteers
- 381 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Bowel Preparation for Colonoscopy
Split Dose Golytely With Amitiza Pretreatment Versus Split Dose Golytely Plus Placebo in Outpatient Colonoscopy
The primary outcomes of this procedure will be: 1. The cleanliness of the prep as measured by the Ottawa Scale (attachment a). Secondary outcomes will be: 1.
- Trial name
- NCT00611442
- Testing
- lubiprostone
- Where
- United States
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Vital Pulp Therapies, Pulpotomy
Comparison of Sodium Hypochlorite Gel and Solution With and Without Nanoparticles for Postoperative Pain After Pulpotomy in Permanent Mandibular Molars
This randomized clinical trial aims to compare the effect of 2% sodium hypochlorite gel and solution, with and without chitosan nanoparticles, on postoperative pain following pulpotomy in mature permanent mandibular molars with…
- Conditions
- Vital Pulp Therapies, Pulpotomy, Irriversible Pulpitis, Postoperative Pain
- Trial name
- NaOCl Pulpotom (NCT07774130)
- Testing
- Sodium Hypochlorite gel 2%, Sodium hypochlorite gel 2% with chitosan nano particles, Sodium hypochlorite solution 2% with chitosan nanoparticles
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Tooth Hypersensitivity
Hypersensitivity and Color Changes of Bleached Teeth Using Different Remineralizing Agents
The aim of this in vivo study is to evaluate the post-bleaching enamel hypersensitivity and the possible color changes following the application of arginine and nano-hydroxyapatite remineralizing solutions after enamel bleaching…
- Trial name
- NCT04875000
- Testing
- Remineralizing agent I application, Remineralizing agent II application, Remineralizing agent III application
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Healthy
Metabolism and Pharmacokinetics of [14C]-DK-AH 269 CL in 12 Healthy Male Volunteers
To investigate absorption, metabolism and excretion of [14C]-DK-AH 269 CL after oral and intravenous administration in healthy volunteers To assess the safety and tolerability of DK-AH 269 CL after oral and intravenous…
- Trial name
- NCT02264028
- Testing
- [14C]-DK-AH 269 CL, solution for infusion, [14C]-DK-AH 269 CL, drinking solution
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Haemophilus Influenzae Infection, Vaccines
Safety and Reactogenicity Trial of Vaccine for the Prevention of Infections Caused by Haemophilus Influenzae Type b
Trial purpose is to evaluate the safety, tolerability and reactogenicity of the Vaccine for the prevention of infections caused by Haemophilus Influenzae Type b in volunteers aged 18-50.
- Trial name
- NCT05401305
- Testing
- Vaccine for the prevention of infections caused by Haemophilus influenza type b
- Where
- Russia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- St. Petersburg Research Institute of Vaccines and Sera
Nasal Allergies, Allergies
Safety and Efficacy of AL-53817 Nasal Spray Solution
The purpose of this study was to determine the maximum tolerated dose of AL-53817 (Stage A) and evaluate the safety and efficacy of AL-53817 for the treatment of allergic rhinitis (Stage B).
- Trial name
- NCT01454505
- Testing
- AL-53817 nasal spray solution, Vehicle nasal spray
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Allergic Conjunctivitis
Use of BEPREVE (Bepotastine Besilate Ophthalmic Solution) 1.5% for Allergic Conjunctivitis and Contact Lenses
The purpose of this study is to assess if BEPREVE (bepotastine besilate ophthalmic solution) 1.5% will have an effect on contact lens wear in patients with contact lens intolerance due to allergic conjunctivitis.
- Trial name
- NCT01337557
- Testing
- Bepotastine
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hom, Milton M., OD, FAAO
Contact Lens Care
Evaluation of an Investigational Multi-Purpose Disinfecting Solution for the Care of Silicone Hydrogel Soft Contact Lenses
The objective of the study was to clinically evaluate the safety and effectiveness of a new multi-purpose disinfecting solution in patients wearing silicone hydrogel soft contact lenses.
- Trial name
- NCT00382902
- Testing
- OptiFree Multi-Purpose Disinfecting Solution
- Where
- United States
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Post-Traumatic Stress Disorder
Quantitative Electroencephalography (QEEG) and Low-resolution Electromagnetic Tomography (LORETA) Analysis in Post Traumatic Stress Disorder (PTSD) Patients
In this study the Quantitative Electroencephalography and low resolution topographic analysis of chronic Post-traumatic stress disorder and normal subjects will be compared.
- Trial name
- NCT01020695
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Beersheva Mental Health Center
Postprandial Glucose, Platelet Activation
Cimarrón Bean Extrudate Solution on Platelet Function and Biochemical Parameters
This non-randomized acute clinical trial evaluates the effect of consuming a water-based solution of Cimarrón bean extrudate on platelet function and postprandial glycemia in adults.
- Trial name
- CBE-SP (NCT07043829)
- Testing
- SPVCE (Solution Phaseolus vulgaris L. var. Cimarrón Extrudate in Water)
- Where
- Chile
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Talca
Healthy
Multiple Oral Doses of BIBR 1048 MS Solution in Healthy Volunteers
To assess safety, pharmacokinetics and the effect of BIBR 1048 MS on coagulation parameters.
- Trial name
- NCT02170831
- Testing
- BIBR 1048 MS low, BIBR 1048 MS medium 1, BIBR 1048 MS medium 2
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Pulmonary Arterial Hypertension
Dose-Finding, Safety, Pharmacodynamic Effect Study of Sodium Nitrite Inhalation Solution in Normal, Healthy Volunteers
This study is designed to investigate the safety and tolerability of AIR001 Inhalation Solution when administered under conditions of hypoxia and to identify dose levels of drug resulting in a reduction in pulmonary arterial…
- Trial name
- AIR001-CS02 (NCT00814645)
- Testing
- Sodium Nitrite Inhalation Solution
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Aires Pharmaceuticals, Inc.
Seasonal Allergic Rhinitis
Effect of Veramyst and Olopatadine 0.2% Opthalmic Solution on Allergy Symptoms
People who have hayfever or allergic rhinitis often complain about eye symptoms associated with their nasal symptoms. How people with hayfever develop eye symptoms is not clear.
- Trial name
- NCT01007253
- Testing
- PL nasal spray, fluticasone furoate (FF), PL eye drops
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Periodontitis, Diagnose Disease
Serum and Saliva Sirtuin 6, Lipoxin A4, Caspase8 Levels in Correlation With Periodontal Status in Severe Periodontitis
It has been stated that Sirtuin-6 (SIRT6) play a important role in regulation of inflammation, energy metabolism, homeostasis and apoptosis, and SIRT6 may be assosiciated with many diseases.
- Trial name
- NCT05417061
- Testing
- Saliva and serum sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Nocturnal Bruxism
Botulinum Toxin A Injectable Solution in the Management of Bruxism: A Clinical Trial Study
A Clinical Trial Study to investigate the potential performance of BTXA on masseter muscle on patient with nocturnal bruxism and to check the pain scale and share this clinical experience.
- Trial name
- NCT03827122
- Testing
- onabotulinumtoxinA
- Where
- Saudi Arabia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Dehydration
Oral Rehydration Solution in Healthy Adults
This is a prospective, randomized, controlled, blinded, crossover study to evaluate the effects of an oral hydration solution.
- Trial name
- NCT06130475
- Testing
- Oral Rehydration Solution (ORS), Water
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Alveolar Ridge Preservation, Dental Extraction
Mix of Demineralized Freeze-Dried Bone Allograft and Deproteinized Bovine Bone Mineral: a Possible Solution for Alveolar Ridge Preservation?
The purpose of the study is to compare a new grafting material for alveolar ridge preservation to a commonly used and well studied material. Alveolar ridge dimensions as well as histology will be compared.
- Conditions
- Alveolar Ridge Preservation, Dental Extraction, Bone Graft
- Trial name
- NCT06275789
- Testing
- Alveolar ridge preservation
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Viral Infection
Safety and Pharmacokinetics of UV-4B Solution Administered Orally as Multiple Ascending Doses to Healthy Subjects
The purpose of this study is to evaluate the safety and pharmacokinetics of UV-4B oral solution when administered to healthy subjects three times a day (TID) for 7 days.
- Trial name
- NCT02696291
- Testing
- UV-4B 30 mg oral solution, UV-4B 75 mg oral solution, UV-4B 150 mg oral solution
- Where
- 2 sites in United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Emergent BioSolutions
Wound Infection, Complication, Postoperative
Chlorhexidine Gluconate vs Povidone-Iodine Vaginal Cleansing Solution Prior to Cesarean Delivery
Endometritis, an infection of the uterus in the postpartum period, has been shown to complicate the postoperative course of a cesarean delivery in 6% to 27% of cases.
- Trial name
- NCT02915289
- Testing
- Povidone Iodine, Chlorhexidine gluconate
- Where
- United States
- Volunteers
- 1,114 people, healthy volunteers welcome
- Sponsor
- Richmond University Medical Center
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