Clinical trials: Resolution
Bioequivalence
Study on Sapropterin Dihydrochloride Oral Suspension in Healthy Subjects Under Fed Conditions
This is a single center, Phase 1, randomized, open-label, single-dose, 2 treatment, 2-period,2-sequence, crossover study designed to compare the pharmacokinetics (PK) of sapropterin between the Test and Reference products in…
- Trial name
- NCT06987773
- Testing
- RLF-OD032 100 mg/mL oral suspension, Kuvan 100 MG Powder for Oral Solution
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- APR Applied Pharma Research s.a.
Health, Health Adult Subjects
DBM-1152A Inhalation Solution in Chinese Healthy Subjects
This is a Phase Ia, single-center, randomized, double-blind, placebo-controlled, single ascending dose (SAD) study. The primary purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK) of DBM-1152A…
- Trial name
- NCT07447141
- Testing
- DBM-1152A Inhalation Solution
- Where
- China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Joincare Pharmaceutical Group Industry Co., Ltd
Local Anesthesia
Effectiveness of Sodium Bicarbonate Buffered Anaesthetic Solution on Pain During Injection
This study will test the effectiveness of addition of Sodium Bicarbonate as a buffering agent to the anaesthetic solution on minimizing the pain of injection and increasing the onset time and potency of the anaesthetic solution…
- Trial name
- NCT05473819
- Testing
- Buffered Local Anesthesia, Conventional Unbuffered Local Anesthesia
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Educational Problems
Lab Skills Nursing Education Into Effective Clinical Practice During COVID-19: Elsevier Clinical Skill Platform
This study aimed to investigate the effectiveness of utilizing an Elsevier clinical skill platform in clinical nursing education. 1.2. Research hypotheses 1.
- Trial name
- EDU (NCT04977921)
- Testing
- lab session
- Where
- Saudi Arabia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Healthy
Comparison of Polyethylene Glycol With Ascorbic Acid and Oral Sulfate Solution for Bowel Preparation
Colonoscopy is considered by many the preferred mode of screening for colorectal cancer (CRC). The effectiveness of any CRC screening program is critically dependent on an adequate bowel preparation.
- Trial name
- NCT02551198
- Testing
- HAPREP®, SUCLEAR®
- Where
- South Korea
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Healthy
A Study in Healthy Men to Test How BI 764198 is Processed in the Body
The main objective of this trial is to investigate the basic pharmacokinetics of BI 764198 and its metabolites, total radioactivity including mass balance, excretion pathways and metabolism following oral administration to…
- Trial name
- NCT05863130
- Testing
- BI 764198 (C-14) (approach 1), BI 764198 (C-14) (approach 2)
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Comparative Bioavailability of Dronabinol Oral Solution in Healthy Volunteers
The primary objective of this study is to evaluate the comparative bioavailability of a test product of dronabinol oral solution administered under fed conditions to the reference listed drug (RLD) administered to participants…
- Trial name
- NCT02604992
- Testing
- Treatment A, Treatment B, Treatment C
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- INSYS Therapeutics Inc
Adolescent, Anger
Anger Management and Violent Behavior in Adolescents
The research was conducted to examine the effect of solution focused approach on anger management and violent behavior in adolescents.
- Conditions
- Adolescent, Anger, Violent Behavior
- Trial name
- NCT04951271
- Testing
- Solution focused approach
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Healthy
Propolis-Based Solution Application in Extraction Socket Healing
This pilot study evaluated whether a propolis-based topical solution improves soft-tissue healing after tooth extraction. Thirteen patients requiring extraction of two comparable teeth on opposite sides of the mouth were enrolled…
- Trial name
- NCT07665814
- Testing
- Propolis-based topical solution (52% propolis extract, clove oil [Eugenia caryophyllus], and white willow bark [Salix alba] extract), Saline rinse (control)
- Where
- Lebanon
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Telemedicine
The Multi-stakeholder Assessment of Economic and Managerial Determinants and Impacts of Telemedicine
The study aims to conduct a comprehensive evaluation involving multiple stakeholders to assess the factors influencing and the consequences of telehomecare in comparison to traditional care models.
- Trial name
- NCT06171763
- Testing
- Telemedicine
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Buzzi Children's Hospital
Parkinson's Disease
A Sequential Two-Part, Open-Label Study in Healthy Male and Female Subjects
An Open-Label Study in Healthy Male and Female Subjects to Identify the Concentration that Provides Optimal Bioavailability of Levodopa Infused Subcutaneously via a Pump System; and to Compare the Bioavailability of…
- Trial name
- NCT02604914
- Testing
- ND0612, LCIG
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- NeuroDerm Ltd.
Dementia
Development and Evaluation of the DEA App
Background, current situation, and motivation According to current estimates, 100,000 people in Austria suffer from various types of dementia.
- Trial name
- DEA (NCT03819816)
- Testing
- DEA-App, Standard Information group
- Where
- 2 sites in Austria
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Valentin Ritschl
Anatomical Pathological Condition, Educational Problems
3D Printed Enlarged Carpal Models for Anatomy Training
3D modeling enables medical professionals or students to better understand complex structures. In many studies, 3D printed models have been used in the training, treatment and surgery of medical disciplines such as neuroscience…
- Trial name
- NCT06639633
- Testing
- Anatomy Training with Enlarged %100 3D Printed Carpal Model Group, Anatomy Training with Enlarged %50 3D Printed Carpal Model Group, Anatomy Training with Conventional Carpal Models
- Where
- Turkey (Türkiye)
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Pharmacokinetics, Safety Issues
Open Randomized Study of Comparative Pharmacokinetics and Biosimilarity of GP40221 (GEROPHARM LLC, Russia) and Ozempic®.
Study of comparative pharmacokinetics and biosimilarity of drugs containing semaglutide - GP40221 and Ozempic® in healthy volunteers.
- Conditions
- Pharmacokinetics, Safety Issues, Bioequivalence
- Trial name
- NCT06497049
- Testing
- GP40221, ozempic
- Where
- Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Geropharm
Healthy
Bioavailability of BI 44370 TA Drinking Solution or Tablets With and Without a High Fat Meal in Healthy Male and Female Volunteers
The objective of this trial was to evaluate the relative oral bioavailability and pharmacokinetics of BI 44370 TA drinking solution (100 mg and 200 mg) and BI 44370 TA tablets (100 mg as two 50 mg tablets) with and without a high…
- Trial name
- NCT02215746
- Testing
- BI 44370 powder for oral solution, BI 44370 tablet, high fat breakfast
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
TAK-020 Relative Bioavailability and Food Effect Study in Healthy Participants
The purpose of this study is to assess the relative bioavailability of solid oral formulations of TAK-020 in comparison with single dose of TAK-020 oral solution formulation and to evaluate the food effect and potentially the…
- Trial name
- NCT02723201
- Testing
- TAK-020 Captisol Oral Solution, TAK-020 CCT, TAK-020 SDT
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Takeda
Healthy
A Bioequivalence Study of Mirikizumab (LY3074828) Solution in Healthy Participants
The main purpose of this study is to evaluate amount of mirikizumab (test) that gets into the blood stream and how long it takes the body to get rid of it, when given via pre-filled syringe compared to mirikizumab (reference)…
- Trial name
- NCT05644353
- Testing
- Mirikizumab
- Where
- 6 sites in United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Double Incontinence, Faecal Incontinence
Prospective Database of Factors Associated With Faecal vs. Double Incontinence in Patients Referred for High Resolution Anorectal Manometry.
This study aims to verify the results from our previous retrospective cohort analysis by establishing a database of well-characterised patients prospectively.
- Conditions
- Double Incontinence, Faecal Incontinence, Urinary Incontinence
- Trial name
- NCT05550675
- Testing
- Questionnaires
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Bleeding, Tooth Extraction
Effects of Tranexamic Acid Irrigation on Impacted Third Molar Surgery
Tranexamic acid (TXA) is an effective hemostatic agent used to reduce blood loss and the need for transfusion. It is a relatively safe drug with minimal significant side effects.
- Trial name
- NCT06806241
- Testing
- Tranexamic acid, saline irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Metabolic Syndrome, Physical Activity
The Effect of Health Provider's Feedback on Physical Activity Surveillance Using Wearable Device-Smartphone Application for Resolution of Metabolic Syndrome
The Effect of Health Provider's Feedback on Physical Activity Surveillance using Wearable Device-Smartphone Application for Resolution of Metabolic Syndrome; a 12-Week Randomized Control Study
- Trial name
- NCT05630456
- Testing
- Receving feedback, No regular feedback
- Where
- South Korea
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Pusan National University Hospital
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