Clinical trials: Resolution
Iron-refractory, Iron-deficiency Anemia (IRIDA)
Pharmacokinetics and Absolute Bioavailability of Fer-In-Sol and Triferic Administered Orally With Shohl's Solution in Healthy Volunteers
The main purpose is to determine the pharmacokinetics (PK) of Triferic iron administered orally in healthy adult volunteers. It is a randomized multiple treatments, single dose study.
- Trial name
- NCT02767128
- Testing
- Triferic, Fer-In-Sol, Shohl's solution
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Rockwell Medical Technologies, Inc.
Asthma, Asthma Patients
Fixed Triple Inhaled Combination in Asthmatic Patients in a Real-life Setting
The mainstay of asthma treatment are ICSs, mostly and usually combined with LABA. In the past decade LAMA had been accepted as an add-on treatment for patients on GINA treatment Steps 4 and 5.
- Conditions
- Asthma, Asthma Patients, Asthma Bronchiale
- Trial name
- STRENGTH (NCT06786767)
- Testing
- BDP/FF/G (Beclomethasone diprprionate, formoterol fumarate, glycopyrronium bromide) 172/5/9 μg
- Where
- 14 sites in Bulgaria
- Volunteers
- 281 people
- Sponsor
- Chiesi Bulgaria
Acute Infectious Keratoconjunctivitis
Study of INV-102 Ophthalmic Solution in Adults With Acute Infectious Keratoconjunctivitis
Phase 2, randomized study to assess topically administered eyedrops of INV-102 compared to vehicle during 1-week dosing in participants with Acute Infectious Keratoconjunctivitis (AIK).
- Trial name
- NCT05636228
- Testing
- INV-102, Vehicle
- Where
- 12 sites in United States, Thailand
- Volunteers
- 93 people
- Sponsor
- Invirsa, Inc.
Intracranial Atherosclerosis
Vessel Wall and Perfusion Imaging in Intracranial Atherosclerosis
Intracranial atherosclerotic disease (ICAD) is an important cause of ischemic stroke. The occurrence of stroke caused by symptomatic ICAD is significantly different compared with asymptomatic ICAD (19% vs 3.5%), suggesting that…
- Trial name
- NCT02719652
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xiuhai Guo
Atrial Fibrillation Paroxysmal
RiLuzole to Reduce Atrial FIb Study Using Holter Monitoring
Atrial fibrillation (AF) is a growing clinical problem.1 AF is a highly dynamic condition involving episodes of sinus rhythm interspersed with periods of arrhythmia, becoming more difficult to terminate over time.
- Trial name
- SOLUTION (NCT05292209)
- Testing
- Riluzole 50 MG
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of Utah
Nephropathy
Clinical Trial of Anti-PLA2R-IgG Detection Kit (Time-resolved Fluorescence Immunoassay)
Conduct comparative experimental studies on clinical serum samples using assessment reagents and approved products, and evaluate the equivalence between assessment reagents and comparison reagents.
- Trial name
- NCT06456801
- Where
- China
- Volunteers
- 219 people
- Sponsor
- Zhejiang University
Healthy Volunteers
A Study to Compare the Relative Bioavailability of Brigatinib When Swallowed as a Solution Versus When Swallowed as a Tablet in Healthy Adults
The main aim of this study is to compare the amount of brigatinib in the blood of healthy adults after they have swallowed one dose either as a solution or as a tablet.
- Trial name
- NCT06132867
- Testing
- Brigatinib
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Takeda
Irrigation Solution, Chronic Wound
Effectiveness and Safety of Using Prontosan to Treat Bacterial Biofilm
The goal of this prospective, multi-center, randomized, parallel-controlled, open-label clinical study is to evaluate the effectiveness and safety of Prontosan wound irrigation solution comparing with Normal Saline on the removal…
- Conditions
- Irrigation Solution, Chronic Wound, Pressure Injury, Diabetic Foot Ulcer
- Trial name
- NCT06185465
- Testing
- Prontosan Wound Irrigation Solution, Normal Saline
- Where
- 3 sites in China
- Volunteers
- 60 people
- Sponsor
- The First Hospital of Jilin University
Basedow Disease
Clinical and Surgical Outcomes of Total Thyroidectomy in Basedow's Disease: the Effect of Lugol Solution
Preoperative preparation of patient with Basedow's disease is crucial to avoid severe thyrotoxicosis resulting from leakage of thyroid hormone into the circulation at the time of surgery.
- Trial name
- BALU (NCT05784792)
- Testing
- Lugol -
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Padova
Papilloma Viral Infection, CIN1
Evaluation Of The Efficacy Of The Combination Of GLIZIGEN® Oral Solution 1/Day And Vaginal Gel 1/Night For 2 Months In Patients With Cervical Intraepithelial Neoplasia Grade 1 (LSIL/CIN-1) Caused By High-Risk Human Papillomavirus (HPV-AR)
HPV infection can lead to cancer, especially when precancerous lesions have developed and high-risk HPV is present. Glizigen is an oral and intravaginal treatment based on activated glycyrrhizinic acid that has shown potential…
- Conditions
- Papilloma Viral Infection, CIN1, LSIL, Low Grade Squamous Intraepithelial Lesion
- Trial name
- NCT05916911
- Testing
- Glizigen
- Where
- 4 sites in Spain
- Volunteers
- 120 people
- Sponsor
- Catalysis SL
Chronic Obstructive Pulmonary Disease, COPD
Sunovion Brovana Versus Serevent Inspiratory Capacity High Resolution Computed Tomography
This is a PI-initiated study taking place only at UCLA, sponsored by Sunovion. The investigators plan to enroll about 20 subjects who are at least 40 years old and have Chronic Obstructive Pulmonary Disease (COPD).
- Conditions
- Chronic Obstructive Pulmonary Disease, COPD, Emphysema, Chronic Bronchitis
- Trial name
- NCT01361984
- Testing
- Nebulized arformoterol, Salmeterol
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles
Hematological Diseases, Allogeneic Stem Cell Transplantation
Long-term Versus Short-term Sequential Therapy (Intravenous Itraconazole Followed by Oral Solution) of Itraconazole as Primary Prophylaxis in Patients Undergoing Allogeneic Stem Cell Transplantation
The primary objective of this study is to evaluate the efficacy and safety profile of itraconazole as in primary prophylaxis The second objective of this study is to find the difference between long-term versus short-term…
- Trial name
- NCT01160952
- Testing
- itraconazole
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Pharmacokinetics, Safety Issues
Open Randomized Study of Comparative Pharmacokinetics and Biosimilarity of GP40221 (GEROPHARM LLC, Russia) and Ozempic®.
Study of comparative pharmacokinetics and biosimilarity of drugs containing semaglutide - GP40221 and Ozempic® in healthy volunteers.
- Conditions
- Pharmacokinetics, Safety Issues, Bioequivalence
- Trial name
- NCT06497049
- Testing
- GP40221, ozempic
- Where
- Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Geropharm
Malaria
Open Label Pharmacokinetic Study of OZ439 and Piperaquine on Administration of OZ439+TPGS Granules for Oral Suspension Alone or With Either Piperaquine Phosphate Tablets or Granules for Oral Solution in Healthy Volunteers
A healthy volunteer study to characterise the exposure of the two study medications, following administration of OZ439 + TPGS granules with piperaquine phosphate granules (intended for children) and with piperaquine phosphate…
- Trial name
- NCT01958619
- Testing
- 1440mg PQP tablets, 960mg PQP tablets, 800mg OZ439 + TPGS
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Medicines for Malaria Venture
Shoulder Pain
High Resolution Ultrasound in Evaluation of Shoulder Pain Guided by MRI
To asses causes of shoulder pain by Ultrasound in guide of MRI diagnosis to help Ultrasound to be used alone in the future
- Trial name
- NCT03891992
- Volunteers
- 50 people
- Sponsor
- Assiut University
Intraventricular Hemorrhage
Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III
The overall objective of this Phase III clinical trial is to obtain information from a population of 500 ICH subjects with intraventricular hemorrhage (IVH), representative of current clinical practice and national demographics…
- Trial name
- CLEAR III (NCT00784134)
- Testing
- Alteplase, Normal saline
- Where
- 81 sites in United States, Brazil and 7 more
- Volunteers
- 500 people
- Sponsor
- Johns Hopkins University
Severe Burn Injury
Balanced Volume Replacement Therapy With Ringer's Acetate Solution in Burn Injury
This observational study compares the influence of Ringer's Lactate solution and Ringer's Acetate solution on organ function scores following severe burn injury.
- Trial name
- VoLTRAB (NCT00609700)
- Where
- Germany
- Volunteers
- 82 people
- Sponsor
- Klinikum St. Georg gGmbH
Human Papilloma Virus, Anal Squamous Cell Carcinoma
High Resolution Anuscopy Study
The majority of anal squamous cell carcinomas (SCC) stem from infection with high-risk human papillomavirus (HPV). Anal SCC is rare among the general population but affects several populations disproportionately.
- Trial name
- NCT06697964
- Testing
- HRA
- Where
- Belgium
- Volunteers
- 500 people
- Sponsor
- Universitair Ziekenhuis Brussel
Catheter Infections, End-stage Renal Disease
Comparison of a TauroLock™ Based Regimen to 4% Citrate as Lock Solution in Tunneled Haemodialysis Catheters for the Prevention of Bacteraemia and Dysfunction
Catheter infections and dysfunctions are a major cause of morbidity and mortality in haemodialysis patients. According to the US Renal Data System, infection is the second leading cause of death in dialysis patients and the…
- Trial name
- NCT02789501
- Testing
- 4% citrate lock solution regimen, TauroLock lock solution regimen
- Where
- Austria
- Volunteers
- 106 people
- Sponsor
- Medical University of Vienna
Nocturia, Sleep Disturbanc
A Community-based Solution for Nocturia: Integrating Digital Technology and Behavioral Interventions
Nocturia is a prevalent and distressing condition among older adults in Taiwan, significantly impacting sleep quality, mental health, and fall risks.
- Conditions
- Nocturia, Sleep Disturbanc, Quality of Life
- Trial name
- NCT07734207
- Testing
- Home Uroflowmetry, Voiding Diary
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
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