Clinical trials: Resolution
Bronchiolitis, Viral, Saline Solution, Hypertonic
Hypertonic Saline for Acute Bronchiolitis
The purpose of this study is to determine whether nebulized 3% hypertonic saline (HS) improves respiratory distress in children 2-23 months presenting to the emergency department (ED) with acute bronchiolitis with persistent…
- Trial name
- NCT01247064
- Testing
- Nebulized 3% saline, Nebulized 0.9% Normal Saline
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Children's Hospital of Philadelphia
Ocular Redness
Study Evaluating the Safety and Efficacy of Brimonidine Tartrate Ophthalmic Solution in Adult and Geriatric Subjects
The purpose of this study is to evaluate the safety and efficacy of brimonidine tartrate 0.025% ophthalmic solution used four times daily in a population of adult and geriatric subjects
- Trial name
- NCT01675609
- Testing
- Brimonidine tartrate 0.025%
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Eye Therapies, LLC
Melanoma
Using High Resolution Function Imaging To Detect Melanoma and Dysplastic Nevi
A novel infrared imaging tool to aid in the clinical detection of atypical pigmented lesions and melanoma is developed. Goals include evaluation of the utility of high-resolution infrared scanning of cutaneous lesions in the…
- Trial name
- NCT01118832
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Spinal Diseases, Spinal Fusion
Intraoperative Disinfection by Pulse Irrigation With Povidone-Iodine Solution in Spine Surgery
The purpose of this study was to evaluate the efficacy, in preventing Spinal Surgical Infection, of intraoperative pulsatile irrigation with a 2000-ml saline solution of PVP-Iodine in a group of patients undergoing complex spine…
- Conditions
- Spinal Diseases, Spinal Fusion, Spine Injury, Infection, Hospital
- Trial name
- NCT03249363
- Testing
- Group A - Pulsed PVP-I Irrigation
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rome Tor Vergata
Arm Pain, Arm Aesthetics
Cold Versus Warm Tumescent Solution in Arm Liposculpture
The goal of this clinical trial is to evaluate whether the temperature of tumescent solution (cold vs. warm) affects postoperative outcomes in adults undergoing arm liposculpture.
- Conditions
- Arm Pain, Arm Aesthetics, Liposuction, Safety of Intervention
- Trial name
- NCT06865911
- Testing
- Cold crystalloid infusions, 0.9%NaCl or Ringer's, Warm saline, Liposuction of the arms
- Where
- Colombia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Eternal Beauty SAS
Chronic Obstructive Pulmonary Disease
An Efficacy Study of BCS Clearing the Oral Colonized Bacterium in Hospitalized Patients With COPD
The purpose of study is to evaluate the efficacy and safety of Benzalkonium Chloride Solution clearing the oral colonized bacterium in hospitalized patients with COPD.
- Trial name
- NCT02269800
- Testing
- Benzalkonium chloride solution, Normal saline
- Volunteers
- 60 people
- Sponsor
- Lustre Pharmaceutical Lab Co., Ltd
Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD)
Pharmacodynamic and Pharmacokinetic Dose Ranging Study of Tiotropium Bromide Administered Via Inhalation Solution in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Pharmacodynamic and Pharmacokinetic Dose Ranging Study of Tiotropium Bromide Administered Via Inhalation Solution in Patients With Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- NCT03118765
- Testing
- GSP304 (tiotropium bromide) Inhalation Solution, Spiriva® Respimat® inhalation spray
- Where
- 25 sites in United States
- Volunteers
- 155 people
- Sponsor
- Glenmark Specialty S.A.
Cystic Fibrosis
Study of Denufosol Inhalation Solution in Patients With Mild to Moderate Cystic Fibrosis Lung Disease
The purpose of this trial is to evaluate the effects of a single dose of denufosol versus placebo on mucociliary clearance in patients with mild to moderate CF lung disease
- Trial name
- NCT00425165
- Testing
- denufosol tetrasodium (INS37217) Inhalation Solution
- Volunteers
- 6 people
- Sponsor
- Merck Sharp & Dohme LLC
Burns, Intoxication
Efficacy and Safety of Rheosorbilact® Solution for Infusion, in a Complex Therapy of Burns
This study evaluates the efficacy and safety of Rheosorbilact®, solution for infusion ("Yuria-Pharm" LLC), in comparison with Ringer's Lactate, solution for infusion, in a complex therapy of burns.
- Trial name
- NCT04152096
- Testing
- Rheosorbilact®, Ringer lactate
- Where
- 5 sites in Kazakhstan, Moldova and 2 more
- Volunteers
- 118 people
- Sponsor
- Yuria-Pharm
Intracranial Hypertension
Mannitol Versus Hypertonic Saline Solution in the Treatment of Elevated Intracranial Pressure
The purpose of this study is to determine whether mannitol is as effective as hypertonic saline solution in the treatment of elevated intracranial pressure in patients with brain injury.
- Trial name
- NCT00447018
- Testing
- 20% mannitol, 7.45% hypertonic saline solution
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Grenoble
Breast Cancer, Early Detection of Cancer
A Prospective Study to Evaluate Clinical Performance of Thermalytix in Detecting Breast Cancers
The purpose of this study is to determine the clinical performance of AI-based Thermalytix with the current standard-of-care diagnostic modalities in women.
- Trial name
- NCT04688086
- Testing
- Thermalytix
- Where
- India
- Volunteers
- 687 people, healthy volunteers welcome
- Sponsor
- Niramai Health Analytix Private Limited
Left Ventricular Thrombosis
Apixaban Versus Warfarin in Patients With Left Ventricular Thrombus
The purpose of this study is to compare the novel oral anticoagulant apixaban with the standard therapy of warfarin on the size reduction or resolution of left ventricular thrombus over 3 months.
- Trial name
- NCT02982590
- Testing
- Apixaban 5 MG Oral Tablet [ELIQUIS], Warfarin Sodium
- Where
- Malaysia
- Volunteers
- 27 people
- Sponsor
- Universiti Sains Malaysia
Hereditary Cancer-Predisposing Syndrome
Inherited Risk Evaluation Tool (InheRET): Identifying Patients at Increased Risk for Hereditary Disease
This study will evaluate the impact InheRET™, an online family history gathering and risk assessment reporting tool, has on facilitating National Comprehensive Cancer Network(NCCN) guideline compliant referrals for cancer genetic…
- Trial name
- NCT04510896
- Testing
- InheRET, Patient Acceptance, Physician Acceptance Survey
- Where
- 4 sites in United States
- Volunteers
- 2,232 people, healthy volunteers welcome
- Sponsor
- InheRET, Inc
Coronary Artery Disease, Acute Coronary Syndrome
Smartphone GUIded MeDication AdherencE and Rehabilitation in Patients With Coronary Artery Disease
This study evaluates a smartphone-based cardiac rehabilitation program in adults with coronary artery disease. Half of patients will participate in a smartphone-based cardiac rehabilitation program while the other half will…
- Trial name
- smartGUIDE (NCT03207646)
- Testing
- BrightHeart®
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Stanford University
Corneal Diseases
The Relation Between BSS Solution Temperature and Endothelial Cells and Post Phaco Discomfort
patients underwent phacoemulsification , balanced saline solution used during the operation will be at room temperature in one group and cool 2.7 c in the other group.
- Trial name
- NCT06904560
- Testing
- phacoemulsification
- Volunteers
- 40 people
- Sponsor
- Sohag University
Primary Open Angle Glaucoma, Ocular Hypertension
Study to Compare the Safety and Efficacy of ALZ-1101 to Latanoprost in Patients With Intraocular Pressure Inadequately Controlled by Latanoprost
This is a pilot, proof of concept study to evaluate the safety and efficacy of ALZ-1101 dosed once daily for 28 days compared to latanoprost 0.005% ophthalmic solution in patients with elevated intraocular pressure not adequately…
- Conditions
- Primary Open Angle Glaucoma, Ocular Hypertension, Elevated Intraocular Pressure
- Trial name
- NCT01896180
- Testing
- ALZ-1101, Latanoprost
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Alleanza Pharmaceuticals, Inc.
Post-ERCP Pancreatitis, Pancreatitis
Short-Stay Aggressive Hydration to Prevent Post-ERCP Pancreatitis
Post-ERCP pancreatitis (PEP) is the most common serious adverse event after endoscopic retrograde cholangiopancreatography (ERCP), occurring in roughly 7-15% of patients.
- Trial name
- PuSH (NCT07776561)
- Testing
- Short-Stay Aggressive Hydration, Standard Peri-procedural Hydration, Rectal Indomethacin
- Where
- Australia
- Volunteers
- 1,300 people
- Sponsor
- Westmead Hospital
Cystic Fibrosis
Clearing Lungs With Epithelial Sodium Channel (ENaC) Inhibition in Cystic Fibrosis (CF)
The goal of the study is to evaluate the safety and tolerability of P-1037 and to determine whether the combination of P-1037 with hypertonic saline or P-1037 alone has a greater effect on lung function in patients with CF than…
- Trial name
- CLEAN-CF (NCT02343445)
- Testing
- P-1037, Hypertonic Saline, Saline
- Where
- 33 sites in United States
- Volunteers
- 142 people
- Sponsor
- Parion Sciences
Age Related Macular Degeneration, Glaucoma
Prospective Study Phase: Retinal Oxygen Saturation, Blood Flow, Vascular Function and High Resolution Morphometric Imaging in the Living Human Eye
Canadians fear loss of vision more than any other disability. Vision loss has an enormous impact on quality-of-life and is extremely costly from a societal and economic perspective.
- Conditions
- Age Related Macular Degeneration, Glaucoma, Diabetic Retinopathy.
- Trial name
- NCT01348672
- Where
- Canada
- Volunteers
- 381 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Simulation, Training
Simulations Impact on Nursing Students Conflict Resolution and Problem-Solving Skills
Scenario-based simulation training effectively enhances nursing students' core competencies, communication, teamwork, problem-solving, and decision-making skills, better preparing them for real-world experiences.
- Trial name
- NCT06592729
- Testing
- education
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
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