Clinical trials: Resolution of Pathologic Process
Liposuction, Bruising
EFFECTS OF TRANEXAMIC ACID IN TUMESCENT SOLUTION FOR LIPOSUCTION PROCEDURES
The goal of this trial is to evaluate the effect of adding Tranexamic Acid (TXA) to the tumescent solution used in arm liposuction on postoperative outcomes.
- Conditions
- Liposuction, Bruising, Inflammation, Skin Condition
- Trial name
- ARMTXA (NCT06648265)
- Testing
- Tranexamic Acid (Topical), Tumescent solution with dilute lidocaine and epinephrine
- Where
- Colombia
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Total Definer Research Group
Bone Loss in Jaw, Dental Diseases
Point of Care, High Resolution and 3-Dimensional Ultrasonography
The overall purpose of this study is to establish an ultrasound technique to aid in oral and dental examination of soft and hard tissues.
- Trial name
- NCT05282212
- Testing
- Ultrasound Scan
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Normal
Study: Manometry With & Without Lidocaine
The purpose of this study is to determine whether subjects report a difference in comfort with High Resolution Pharyngeal Manometry (HRPM) conducted following application of lidocaine as an anesthetic as compared to HRPM…
- Trial name
- NCT03349112
- Testing
- 4% Lidocaine Spray, 2% Viscous Lidocaine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Coronary Atherosclerosis
Coronary Atherosclerosis T1-Weighted Characterization (CATCH)
This study proposes to develop an MRI technique named Coronary Atherosclerosis T1-weighed Characterization (CATCH) that will improve the quality and reliability of coronary atherosclerosis evaluation, as well as simplify the…
- Trial name
- CATCH (NCT03504956)
- Testing
- Cardiac MRI, Contrast, Beta blocker
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Healthy Skin, Nevus
The Application of Non-invasive and Cellular Level Resolution Fullfield Optical Coherence Tomography: Establishment and Analysis of Subcutaneous Cellular Level Image Database of Anatomical Locations in Healthy Volunteers and Evaluation of Usability
ApolloVue® S100 Image System is a medical device class II. The objective of this protocol is to image skin of healthy volunteers and to evaluate the performance of full-field optical coherence tomography (FF-OCT) device - the…
- Trial name
- NCT04406454
- Testing
- ApolloVue® S100 Image System
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Sun Damaged Skin
Photoprotective Effects of a SPF50+ Sunscreen on Skin Genotoxicity Induced by Repeated Chronic Outdoor Sun Exposure
Between 2 and 3 million non-melanoma skin cancers and 132,000 melanoma skin cancers occur globally each year. Sun protection continues to be a major public health issue and has always been a priority research area for Pierre…
- Trial name
- NCT05926791
- Testing
- Cosmetic product
- Where
- France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Hearing Loss
Restoration of Spectral Resolution With Hearing-aid Amplification
The objective of this study protocol is to determine the efficacy of using aided measures of spectral resolution to set the dynamic range of hearing with hearing-aid amplification.
- Trial name
- NCT03850678
- Testing
- Hearing Aid
- Where
- United States
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Endometriosis Related Pain, Overactive Bladder
A Trial to Learn How a New Liquid Form of BAY1817080 is Tolerated and Taken up by the Body of Healthy Male Participants (Part A). By Labeling BAY1817080 With a Radioactive Substance (Carbon 14) Researchers Want to Learn How the Study Drug is Processed and Excreted by the Body After Dosing (Part B)
Researchers are looking for a new way to treat people suffering either from a condition where the bladder is unable to hold urine normally (overactive bladder), or a condition in which tissue similar to the tissue that normally…
- Conditions
- Endometriosis Related Pain, Overactive Bladder, Diabetic Neuropathic Pain, Refractory or Unexplained Chronic Cough
- Trial name
- NCT04487431
- Testing
- BAY1817080, [14C]BAY1817080
- Where
- Netherlands
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Bayer
Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocellular Carcinoma
Application of Super-Resolution Ultrasound (SRUS) in Liver Tumor
The macroscopic vascular supply of liver tumors varies considerably according to histological subtype, lesion size, and disease stage.
- Conditions
- Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocellular Carcinoma, Hepatic Hemangioma, Focal Nodular Hyperplasia
- Trial name
- SRUS (NCT07707661)
- Testing
- Perform super-resolution ultrasound imaging on the study population
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Eastern Hepatobiliary Surgery Hospital
Dehydration in Children, Fluid Therapy
Boluses of Ringer's in Surgical Kids (BRiSK Study)
Traditional protocols for intravenous fluid administration in children who have undergone a major abdominal or thoracic operation are based on a landmark paper published in 1957 by Holliday and Segar.
- Trial name
- BRiSK (NCT05285371)
- Testing
- Urinalysis (UA), Complete Metabolic Panel (CMP), Glucose Stick Test (d-Stick)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Healthy Subjects
Normative Metrics of High-Resolution Anorectal Manometry With the Use of Solid-State Catheter in a Healthy Russian Cohort
High resolution anorectal manometry (HRAM) normative values are still need to be studied in different populations and with the use of different (solid-state and water-perfused) systems.
- Trial name
- NCT03918213
- Testing
- High-Resolution anorectal manometry with the use of solid-state catheter
- Where
- 2 sites in Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Russian Academy of Medical Sciences
Healthy
Normal Values for Esophageal High Resolution Manometry in an Advanced Protocol Including Liquid Swallows and a Solid Test Meal
Normal values for measurements of high resolution manometry in a protocol which includes isolated liquid swallows in upright and recumbent position, free drinking of water, a solid test meal and a postprandial observational…
- Trial name
- Rice (NCT02407938)
- Testing
- Rice meal
- Where
- Switzerland
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Cardiac Disease
Accelerated Contrast-Enhanced High Resolution Whole Heart Cardiac MRI
Coronary artery disease (CAD) is the leading cause of death in the United States. Cardiac MRI is a non-invasive non-ionizing technique for a comprehensive cardiac exam, which can be used in the diagnosis of CAD.
- Trial name
- NCT02550366
- Testing
- MRI Contrast
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Constipation, Children
Comparison of Anorectal Manometry and 3D Manometry in Diagnosis of Functional Disorders in Children
Pressures measured by manometric solid-state catheters may differ according to the type of the catheter and specific anatomy and physiology of anorectum.
- Conditions
- Constipation, Children, Fecal Incontinence
- Trial name
- NCT02812823
- Testing
- High-resolution anorectal manometry
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Gastric Cancer (GC), Premalignant Lesion
AI-Based Risk Prediction Model for Upper Digestive Tract Cancer
Upper digestive tract cancers are often preceded by pre-malignant lesions, but there is limited evidence regarding optimal risk prediction models and screening strategies for disease progression and cancer development.
- Conditions
- Gastric Cancer (GC), Premalignant Lesion, Gastric Intestinal Metaplasia, Atrophic Gastritis
- Trial name
- NCT07605312
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Head and Neck Cancer, Prostate Cancer
Application of High Resolution Diffusion-weighted MR Imaging Pulse Sequence in Head and Neck, and Prostate Cancers
Magnetic resonance imaging (MRI) is a diagnostic study that makes pictures of organs of the body using magnetic field and radio frequency pulses that can not be felt.
- Trial name
- NCT01535898
- Testing
- MRI scanner with sequence
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer Detection
Clinical Feasibility Study of Upright, Low-dose, High-resolution, 3D Breast CT (UBCT).
The investigators are doing this study to find out if a new kind of breast imaging (called upright dedicated breast CT or UBCT) can help doctors to see the small structures in breast tissue more clearly in 3-D and without…
- Trial name
- UBCT (NCT07705100)
- Testing
- Low dose, upright, dedicated breast CT
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Glaucoma Associated With Other Ocular Disorders
oCular Examination at Cell RESolution With Optical TransmissionTomography
Understanding the pathogenesis of eye diseases has benefited greatly from recent advances in ophthalmic imaging. However, current clinical imaging systems, such as optical coherence tomography (OCT), are limited in terms of…
- Trial name
- CERES-OTT (NCT06976034)
- Testing
- Optical Transmission Tomography (OTT), Optical Coherence Tomography (OCT), Specular Microscopy (SM)
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Gaming, Gambling
Vulnerability Markers in Pathological Gambling
Addictions without substances are an emergent problem giving rise to a recent and increasing request of care. Among these new addictions, pathological gambling and pathological online video gaming which are up.
- Trial name
- GambleMMORe (NCT02873572)
- Testing
- step 1: online assessment, step2: biomarkers of gamblers/gamers
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Children, Anorectal Disorder
Normal Values for 3D High Resolution Anorectal Manometry in Children
Anorectal 3D high resolution manometry (3D HRM) is the most advanced version of manometry equipment and has been recently introduced into clinical practice.
- Trial name
- NCT02236507
- Testing
- 3D high resolution anorectal manometry
- Where
- Poland
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw