Clinical trials: Resolution of Pathologic Process
Surgery, Nurse's Role
Effects of Aromatic Solution Applied After Surgery
Today, surgical applications are used to solve many health problems. In order for the surgical intervention to take place, anesthesia applications are often required.
- Conditions
- Surgery, Nurse's Role, Throat, Sore, Thirst
- Trial name
- NCT05522023
- Testing
- group treated with aromatic solution, group treated with drinking water
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Healthy
High-resolution Phosphocreatine and Creatine Mapping of Human Muscle and Brain
In this study, we aim to develop and validate a noninvasive approach for quantifying and imaging energy metabolism, without contrast agents, on widely available clinical MRI scanners.
- Trial name
- NCT04234880
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Ischemic Stroke
Mexidol® Safety and Efficacy in Treatment of Hyperacute and Acute Ischemic Stroke
The primary objective of this study is to further define the mechanisms of action of Mexidol® (solution for intravenous and intramuscular injection, 50 mg/ml) and Mexidol® FORTE 250 (film-coated tablets, 250 mg) in the hyperacute…
- Trial name
- NCT07575984
- Testing
- Mexidol, Glycine
- Where
- 9 sites in Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Pharmasoft
Cystic Fibrosis
Bone Microarchitecture in Young Cystic Fibrosis Patients
Patients with cystic fibrosis are at risk of developing low bone mineral density (BMD) potentially leading to pathological fractures at adult age.
- Trial name
- NCT01788267
- Testing
- scan examination HR-pQCT
- Where
- France
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Dehydration
Oral Rehydration Solution in Healthy Adults
This is a prospective, randomized, controlled, blinded, crossover study to evaluate the effects of an oral hydration solution.
- Trial name
- NCT06130475
- Testing
- Oral Rehydration Solution (ORS), Water
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Obstetric Anal Sphincter Injury
A Comparison of THD® Anopress With High Resolution Anorectal Manometry
Currently, high resolution anorectal manometry (HDARM) is used as gold standard to measure anal sphincter pressures in women who have sustained a third or fourth degree perineal tears (obstetric anal sphincter injuries).
- Trial name
- NCT07083908
- Testing
- THD® Anopress (Sensyprobe) first, High Resolution Anorectal Manometry first
- Where
- United Kingdom
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Osteoporosis, Sarcopenia
Bone Microstructure by Using HR-pQCT After Esophagectomy
Esophagectomy is most curative treatment to esophageal cancer. However, osteoporosis , which is characterized by both the loss of bone mass and the deterioration of bone architecture, is a serious complication in the long course…
- Conditions
- Osteoporosis, Sarcopenia, Esophageal Cancer
- Trial name
- NCT05812235
- Testing
- esophagectomy
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Nagasaki University
Peripheral Artery Disease
The Value of Super-resolution Ultrasound Imaging for Peripheral Artery Disease
Peripheral artery disease (PAD) is a chronic atherosclerotic disorder characterized by stenosis or occlusion of the extracranial arteries distal to the aortic arch, most commonly affecting the lower extremities.
- Trial name
- NCT07374601
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Branch Retinal Artery Occlusion, Central Retinal Artery Occlusion
Retinal Oxygen Saturation, Blood Flow, Vascular Function and High Resolution Morphometric Imaging in the Living Human Eye
Canadians fear loss of vision more than any other disability. Vision loss has an enormous impact on quality-of-life and is extremely costly from a societal and economic perspective.
- Conditions
- Branch Retinal Artery Occlusion, Central Retinal Artery Occlusion, Branch Retinal Vein Occlusion, Central Retinal Vein Occlusion
- Trial name
- NCT01348633
- Where
- Canada
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Caregivers
Cereset Research for Caregivers
Caregivers experience high levels of prolonged stress that can lead to chronic problems with health, including increased risk of cardiovascular disease that is linked to autonomic dysregulation.
- Trial name
- NCT05209438
- Testing
- Cereset Research
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Sleep Apnea
High-resolution Oximetry to Diagnose Obstructive Sleep Apnea
The aim of this study was to compare an overnight digital monitoring device (ODM) with home sleep apnea testing (HSAT) using respiratory flow and effort parameters in a large population sample, who were in a waiting list for…
- Trial name
- NCT04366193
- Testing
- Oximetry
- Where
- Brazil
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Conflict, Family Relations
Learning to Resolve Family Conflict
This study will evaluate the effectiveness of conflict resolution training for families with preschool and elementary school-aged children.
- Trial name
- NCT00059709
- Testing
- Mediated Negotiation Training
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Covid19
Description of Immunologic, Enzymatic and Metabolic Biomarkers Associated to the Severity of COVID-19 (SARS-CoV-2) and Its Resolution
Prospective study to describe the immunological, metabolic and serologic profile in the acute and post acute phases of Coronavirus disease (COVID-19)
- Trial name
- BIOMARK-COVID (NCT04664023)
- Testing
- Blood collection at Day 8, Day 16, Day 24, Month 6 and Month 12 after first symptoms from SARS-CoV-2 infection., Blood collection at 1st injection of vaccine against COVID-19, at at second injection of vaccine, at Month 1, Month 2, Month 6 and Month 12 after second injection of vaccine for volunteers
- Where
- France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Safety and Tolerability
PK and PD Profile of Dance 501 in Healthy, Non-diabetic Subjects With Mild to Moderate Asthma or COPD
This will be a randomized, open-label, active-controlled, single dose crossover study with either three or four treatment periods.
- Trial name
- NCT03307512
- Testing
- inhaled human insulin, Insulin Lispro (Humalog U-100)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dance Biopharm Inc.
Stargardts, Retinitis Pigmentosa
High Resolution Retinal Imaging
Studying the morphology and function of the normal and diseased retina in vivo is needed for advancing the detection, diagnosis, and treatment of retinal disease.
- Conditions
- Stargardts, Retinitis Pigmentosa, Age-related Macular Degeneration, Choroideremia
- Trial name
- AOSLO (NCT01866371)
- Testing
- Retinal imaging
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Muscular Injury
Almond Supplementation and Exercise Recovery
The PURPOSE of this study is to see if eating almonds for four weeks will reduce muscle damage, soreness, and inflammation during several days of recovery from eccentric exercise.
- Trial name
- NCT04958018
- Testing
- Almonds, Snack bars
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Infertility, Female
Cabergoline Before or After Oocyte Collection for Follicular Resolution
Randomized trial comparing the efficacy of two different times of administration of cabergoline in patients undergoing controlled ovarian stimulation and oocyte collection.
- Trial name
- NCT04096027
- Testing
- Cabergoline Pill
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Fertility Center of Las Vegas
Peri-implant Mucositis, Peri-Implantitis
Experimental Peri-implant Mucositis on Implant Sites That Were Previously Treated With or Without Implantoplasty
This controlled clinical trial will assess clinically, immunologically, and microbiologically the healing of experimental peri-implant mucositis (PIM) lesions in implants treated previously with implantoplasty (IP) compared to…
- Trial name
- NCT06063876
- Testing
- Induction of experimental peri-implant mucositis, Resolution of experimental peri-implant mucositis
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Periapical Abscess
Resolution of Pain and Swelling After the Use of Neem Leaf Extract Compared to Chlorhexidine Gluconate as an Intracanal Irrigant During Pulpectomy
The trial is to test the resolution of pain, swelling and other signs of periapical infection and the antimicrobial efficacy when using the neem leaf extract compared to chlorhexidine as root canal irrigant in Pulpectomy…
- Trial name
- NCT02943759
- Testing
- Neem leaf extract, Chlorhexidine gluconate
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hemodynamics of Cranial Arteries, Headache
The Hemodynamics Effect of Glibenclamide on Levcromakalim Assessed by High Resolution Magnetic Resonance Angiography (MRA) Technique in a Randomized Double-blind Cross-over Placebo-controlled Study With Healthy Volunteers
To investigate the effect of levcromakalim/placebo infusion on cranial arteries after glibenclamide administration.
- Conditions
- Hemodynamics of Cranial Arteries, Headache, Cerebral Blood Flow
- Trial name
- NCT03886922
- Testing
- Levcromakalim, Saline
- Where
- 2 sites in Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center