Clinical trials: Resolution of Pathologic Process
Pain, Postoperative, Postoperative Pain
Pharmacokinetics and Safety Study of Tapentadol for Postsurgical Pain in Children and Adolescents
The purpose of this study is to evaluate the pharmacokinetic (PK) profile; and safety and tolerability of a single dose of tapentadol oral solution (OS) 1 mg/kg in children and adolescents aged from 6 to less than 18 years with…
- Trial name
- NCT01134536
- Testing
- Tapentadol (OS) Oral Solution
- Where
- 17 sites in United States, Canada and 2 more
- Volunteers
- 45 people
- Sponsor
- Janssen Research & Development, LLC
Pain, Postoperative
Correlation of Eicosanoid and Proresolving Lipid Mediator Temporal Profiles and Resolution of Pain After Thoracic Surgery
The aim of the current pilot study is to investigate whether perioperative dysregulated systemic lipid mediator pathways (more specifically increased pro-inflammatory and decreased anti-inflammatory pathways) are associated with…
- Trial name
- NCT03360175
- Testing
- No intervention - observational study
- Volunteers
- 40 people
- Sponsor
- Brigham and Women's Hospital
Comorbidities and Coexisting Conditions, Alzheimer Disease
An Integrated Solution for Sustainable Care for Multimorbid Elderly Patients With Dementia
The CAREPATH will conduct Technical Validation and Usability (TVU) study by involving ≥ 45 target end users (16 patients with MCI or mild dementia with their informal caregivers and 16 healthcare professionals from various…
- Conditions
- Comorbidities and Coexisting Conditions, Alzheimer Disease, Dementia, Malnutrition
- Trial name
- CAREPATH (NCT05104593)
- Testing
- Intervention tested (CAREPATH)
- Where
- Spain
- Volunteers
- 204 people
- Sponsor
- Complejo Hospitalario Universitario de Albacete
Intracranial Atherosclerotic Disease (ICAD), Intracranial Arterial Stenosis
Photon-counting CT for Intracranial Stent Assessment
Intracranial atherosclerotic disease is an important cause of ischemic stroke, and intracranial stent implantation is increasingly used for patients with severe stenotic lesions.
- Conditions
- Intracranial Atherosclerotic Disease (ICAD), Intracranial Arterial Stenosis, Stent Restenosis, Ischemic Stroke
- Trial name
- NCT07769814
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xin Lou
Pain, Anal Cancer
High-Resolution Anoscopy Perceived Discomfort Study
Study should determine if performing the less uncomfortable part of the exam (the perianal exam) results in less recalled discomfort if performed last vs. if performed first.
- Trial name
- NCT04083053
- Testing
- Perianal Exam, high-resolution anoscopy (HRA) with biopsy
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Wake Forest University Health Sciences
Fuchs' Endothelial Dystrophy
Assessment of Corneal Graft Attachment in Patients With Fuchs Endothelial Corneal Dystrophy Following DMEK Using Ultra-high Resolution OCT
Fuchs endothelial corneal dystrophy (FECD) is a progressive disease characterized by the loss of endothelial cells, thickening of Descemet's membrane and deposition of extracellular matrix in the form of guttae.
- Trial name
- NCT02542644
- Testing
- Ultrahigh resolution Spectral Domain OCT
- Where
- 2 sites in Austria
- Volunteers
- 12 people
- Sponsor
- Medical University of Vienna
Hearing Loss
Restoration of Spectral Resolution With Hearing-aid Amplification
The objective of this study protocol is to determine the efficacy of using aided measures of spectral resolution to set the dynamic range of hearing with hearing-aid amplification.
- Trial name
- NCT03850678
- Testing
- Hearing Aid
- Where
- United States
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Intraventricular Hemorrhage
Clinical Trial on Treatment of Intraventricular Hemorrhage
The specific objective of this trial is to determine the lowest dose and dose frequency possible with the best pharmacokinetic and safety profile and it's ability to remove a blood clot from the ventricular system.
- Trial name
- CLEAR IVH (NCT00650858)
- Testing
- tissue plasminogen activator, rt-PA (thrombolytic) (Cathflo)
- Where
- 25 sites in United States, Canada and 2 more
- Volunteers
- 52 people
- Sponsor
- Johns Hopkins University
Methohexitone Pulmonary Adverse Reaction
Methotrexate Therapy and High-Resolution CT Chest and Spirometry Test Findings in Patients With Rheumatoid Arthritis.
ABSTRACT Background: Rheumatoid arthritis (RA) is characterized by symmetrical erosive synovitis and progressive disability, often complicated by extra-articular manifestations especially in seropositive patients, among them…
- Trial name
- NCT07360340
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Ischemic Stroke, Moya Moya Disease
Super-resolution Clinical Brain Ultrasound
Transcranial Doppler ultrasonography with injection of contrast agent (intravenously to enhance the ultrasound signal) is a non-invasive technique that has been used for years to study intracranial vessels that constitute the…
- Trial name
- ESRCC (NCT05785598)
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Oral Precancer, Oral Cancer
Evaluation of Two Non-Invasive Methods, High-Resolution Microendoscopy and Liquid-Based Cytology, for Detection of Oral Precancer
Cancers of the oral cavity (lip, oral tongue, gingivae, floor of mouth, hard palate, and other mouth tissues including buccal mucosa) are amongst the most common worldwide, with an estimated annual burden of over 300,000 incident…
- Conditions
- Oral Precancer, Oral Cancer, Oral Cancer Screening
- Trial name
- NCT07260344
- Testing
- High-resolution microendoscopy of visible oral precancerous lesions, Standard of care
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- Anil Chaturvedi
Cluster Headache, Craniofacial Pain Syndrome
The Presence and Role of Zygomatic-temporal Neuroma Triggering Cluster Headache
Role of a neuroma of zygomatic-temporal in triggering of a cluster headache. Exploratory diagnosis, resection, and pathological examination of tumor anticipated .
- Trial name
- NCT04845451
- Testing
- Minimal surgical exploration for a neuroma
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- FARO T. OWIESY, M.D
Barrett's Esophagus, Neoplasms
Barrett's Esophagus Related Neoplasia (BERN) Project
The use of high resolution endoscopy (HRE), narrow band imaging (NBI) and chromoendoscopy increases the detection rates of Barrett's esophagus (BE) and early neoplasia.
- Conditions
- Barrett's Esophagus, Neoplasms, Gastroesophageal Reflux
- Trial name
- BERN (NCT00590239)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Midwest Biomedical Research
Head and Neck Cancer
Study of a 1-Millimeter Resolution Clinical Positron Emission Tomography (PET) System in Head and Neck Cancer Imaging
The purpose of this study is to gain initial experience imaging HNC patient using a new PET camera, a 1mm spacial resolution. The goal is to understand image quality of the system and to see how it works in a clinical environment.
- Trial name
- NCT04662554
- Testing
- 1-mm Resolution Clinical PET camera
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Stanford University
Type 2 Diabetes Mellitus
Study of Duodenal-Jejunal Bypass(DJB) as a Potential Cure for Type 2 Diabetes Mellitus
Premise: Complete resolution of Type 2 Diabetes Mellitus with normalization of blood glucose and HbA1c in the abscence of medication support is possible with a surgical procedure named the "Duodenal-Jejunal Bypass (DJB)" a…
- Trial name
- DJB (NCT00562029)
- Testing
- Duodenal-jejunal Bypass
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Sound Shore Medical Center of Westchester
Pancreatic Ductal Adenocarcinoma
High Resolution Ultrasound in Pancreatic Ductal Adenocarcinoma
Pancreatic cancer patients at UHN who have had a CT at UHN and have surgery planned will undergo a high resolution ultrasound pre-operatively and intra-operatively.
- Trial name
- NCT03820661
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto
Coronary Artery Disease
Optimization of SPECT Imaging
Single Photon Emission Computed Tomography (SPECT) is a 3D nuclear medicine imaging technique that is used extensively to study the heart and diagnose heart disease.
- Trial name
- OSCARS (NCT01519973)
- Testing
- SPECT/CT processed with Evolution for CardiacTM software
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Type 2 Diabetes
Diabetes Education/Skills Training and Social Needs Resolution Intervention
This study will test the preliminary efficacy of a nurse case-manager, telephone-delivered intervention that provides diabetes self-management education and skills training and resolves the unmet social needs of older African…
- Trial name
- NCT05935410
- Testing
- DM Social Needs, Usual Care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Medical College of Wisconsin
Organ Transplant
Bone Microarchitecture in the Transplant Patient
The optimal management of calcium and phosphate metabolism regulation in chronic kidney disease (CKD) is important in preventing fracture risk and vascular calcification and thus morbidity and mortality, global and vascular.
- Trial name
- TRANSOS (NCT02729142)
- Testing
- Tibial cortical density evaluation
- Where
- 3 sites in France
- Volunteers
- 137 people
- Sponsor
- Hospices Civils de Lyon
Atrial Fibrillation Recurrent
A Study on the Relationship Between Individualized Low Voltage Regions in Left Atrium and the Mechanism of Atrial Fibrillation in Persistent Atrial Fibrillation Under Ultra-High-Resolution Mapping
The latest OCTARAY multi-electrode mapping catheter and TUREref technology were used to perform ultra-high precision mapping on the left atrial and left atrial auricle of persistent atrial fibrillation in the condition of sinus…
- Trial name
- ILVRA-PAFM-UAH (NCT06694610)
- Testing
- non-pulmonary vein ablation group, only pulmonary vein ablation group
- Volunteers
- 120 people
- Sponsor
- The Third People's Hospital of Chengdu
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.