Clinical trials: Resolution of Pathologic Process
Parkinson's Disease With LRRK2 Mutation, Healthy Controls
Measure of Microglial Activation in the Brain of Parkinson Disease Patients With PET
There is accumulating evidence suggesting that inflammatory processes, through microglial activation, would play a key role in the neurodegenerative process of Parkinson's disease (PD).
- Conditions
- Parkinson's Disease With LRRK2 Mutation, Healthy Controls, Parkinson's Disease Without LRRK2 Mutation
- Trial name
- INFLAPARK (NCT02319382)
- Testing
- PET with the tracer 18F-DPA-714, PET with the tracer 11C-PE2I, MRI
- Where
- France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Covid19
Description of Immunologic, Enzymatic and Metabolic Biomarkers Associated to the Severity of COVID-19 (SARS-CoV-2) and Its Resolution
Prospective study to describe the immunological, metabolic and serologic profile in the acute and post acute phases of Coronavirus disease (COVID-19)
- Trial name
- BIOMARK-COVID (NCT04664023)
- Testing
- Blood collection at Day 8, Day 16, Day 24, Month 6 and Month 12 after first symptoms from SARS-CoV-2 infection., Blood collection at 1st injection of vaccine against COVID-19, at at second injection of vaccine, at Month 1, Month 2, Month 6 and Month 12 after second injection of vaccine for volunteers
- Where
- France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Sleep Initiation and Maintenance Disorders, Anxiety
HIRREM Developmental Study
The purpose of this study is to explore the functional and physiological effects associated with the use of High-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM), as supplemental care, for symptoms of…
- Conditions
- Sleep Initiation and Maintenance Disorders, Anxiety, Post-Traumatic Stress Disorder, Hot Flashes
- Trial name
- NCT02709369
- Testing
- HIRREM
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Wake Forest University Health Sciences
Pneumonia
Does Vitamin D Supplementation Enhance Resolution of Inflammation After Community-acquired Pneumonia?
Previous research has shown that people who have been hospitalised for pneumonia are more likely to die of conditions such as heart attacks, stroke and cancer in the weeks to months after their illness.
- Trial name
- ResolveD-CAP (NCT02802722)
- Testing
- Vitamin D3 supplementation, Peripheral blood and induced sputum sampling, Chest computerised tomography (CT) scans
- Where
- United Kingdom
- Volunteers
- 3 people
- Sponsor
- Queen Mary University of London
Conflict Resolution, Intensive Care Nurses
The Effect of Web-Based Conflict Resolution Training Applied to Intensive Care Nurses
This study will be conducted in a randomized parallel controlled experimental study design to determine the effect of web-based conflict resolution training to be applied to intensive care nurses on the conflict resolution skills…
- Conditions
- Conflict Resolution, Intensive Care Nurses, Web-based Training
- Trial name
- NCT07002645
- Testing
- Web-based conflict resolution training program
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Gazi University
Peripheral Arterial Disease, Claudication, Intermittent
Arterial Imaging of Inflammation and Resolution After Endovascular Surgery
This study evaluates the local inflammatory and resolution response of patients undergoing peripheral vascular intervention like an angioplasty of the superficial femoral artery (SFA) or popliteal artery, or stenting of the iliac…
- Conditions
- Peripheral Arterial Disease, Claudication, Intermittent, Claudication, PAD
- Trial name
- AIIRES (NCT03590769)
- Testing
- 18F-FDG
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- University of California, San Francisco
Chronic Renal Failure
Observational Study of the Use of Extraneal in Peritoneal Dialysis in Patients
The purpose of this study is to evaluate the effectiveness and safety of icodextrin and glucose peritoneal dialysis (PD) solutions for the long dwell exchange in PD patients with continuous ambulatory peritoneal dialysis (CAPD)…
- Trial name
- oSCAR (NCT06492031)
- Testing
- Icodextrin Peritoneal Dialysis Solution, Glucose Peritoneal Dialysis Solution
- Where
- 10 sites in China
- Volunteers
- 439 people
- Sponsor
- Vantive Health LLC
Anal High-grade Squamous Intraepithelial Lesion
Anal HSIL Screening Algorithm
This the propose to use the Multiphase Optimization Strategy Trial (MOST) design to identify an anal HSIL screening algorithm which is most suitable in terms of effectiveness, efficiency, and economy.
- Trial name
- 0007/65 (NCT05531799)
- Testing
- OPTIMIZATION PHASE
- Where
- Thailand
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- Institute of HIV Research and Innovation Foundation, Thailand
Hypercapnic Respiratory Failure, Chronic Obstructive Pulmonary Disease
Telemedicine for Improving Outcome in Inner City Patient Population With Hypercapneic Respiratory Failure
The Hypercapnia Telemedicine Outreach Program (E-TOUCH Study) aims to utilize telemedicine technology, as well as emergency medical services (EMS) home visits to address the problem with poor follow-up and compliance among…
- Conditions
- Hypercapnic Respiratory Failure, Chronic Obstructive Pulmonary Disease, Obesity Hypoventilation Syndrome, Sleep Disordered Breathing
- Trial name
- ETOUCH (NCT03353064)
- Testing
- Vivify, EMS
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Albert Einstein Healthcare Network
Prostatic Neoplasms, Prostate Cancer
Multi-Center Trial of High-resolution Transrectal Ultrasound Versus Standard Low-resolution Transrectal Ultrasound for the Identification of Clinically Significant Prostate Cancer
This trial uses a ultra high-resolution ultrasound system and specialized transducer, intended for use in prostate imaging. The system's image resolution is significantly better than the standard of care, due to its higher…
- Conditions
- Prostatic Neoplasms, Prostate Cancer, Cancer of the Prostate
- Trial name
- NCT02079025
- Testing
- High-resolution ultrasound guided prostate biopsy, Standard ultrasound guided prostate biopsy
- Where
- 5 sites in United States, Canada
- Volunteers
- 1,676 people
- Sponsor
- Exact Imaging
Arthritis, Rheumatoid
Bone Erosions in Rheumatoid Arthritis - Characterization Evaluated by Imaging and Histology
The aim of this study is to describe macro- and micro anatomical structures, including investigating vessels running in osseous pores in finger joints from participants with rheumatoid arthritis (RA) using histology and different…
- Trial name
- BERA (NCT04645381)
- Where
- 2 sites in Denmark
- Volunteers
- 9 people
- Sponsor
- University of Aarhus
COPD
Study to Evaluate the Safety of Long-Term Use of Perforomist® (Formoterol Fumarate)
This study is a multi-center, randomized, placebo-controlled study to evaluate the long-term safety of Perforomist® inhalation therapy in subjects with Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- NCT01488019
- Testing
- Perforomist, nebulization, COPD
- Where
- United States
- Volunteers
- 1,071 people
- Sponsor
- Dey
Chronic Obstructive Pulmonary Disease (COPD)
A Study Characterizing Pharmacodynamic Profiles in Subjects With Chronic Obstructive Pulmonary Disease
The purpose of this study is to characterize the pharmacodynamic profile of Formoterol Fumarate and Foradil Aerolizer
- Trial name
- NCT01113593
- Testing
- Formoterol Fumarate, Foradil Aerolizer
- Where
- 4 sites in United States
- Volunteers
- 45 people
- Sponsor
- Dey
Intracranial Atherosclerosis
Vessel Wall and Perfusion Imaging in Intracranial Atherosclerosis
Intracranial atherosclerotic disease (ICAD) is an important cause of ischemic stroke. The occurrence of stroke caused by symptomatic ICAD is significantly different compared with asymptomatic ICAD (19% vs 3.5%), suggesting that…
- Trial name
- NCT02719652
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xiuhai Guo
Gastro Esophageal Reflux
Thresholds of SLR Maneuver in Obese Patients
There is an increasing interest in High resolution manometry (HRM) in the preoperative assessment of patients with obesity, in order to identify the best surgical option.
- Trial name
- SLR obese (NCT06222177)
- Testing
- Pathophysiologic evaluation
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- IRCCS Policlinico S. Donato
Malignant Neoplasms of Female Genital Organs
Low-Cost Imaging for Cervical Cancer Prevention in the Texas Lower Rio Grande Valley
The purpose of this study is to evaluate a different type of medical equipment called "High-Resolution Microendoscope" (HRME) for the diagnosis of cervical pre-cancerous lesions and cervical cancer.
- Trial name
- NCT02714439
- Testing
- Proflavine, High-Resolution Microendoscopy (HRME)
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Dissecting Aneurysm of Cerebral Artery
Metformin in Patients With Unruptured Vertebrobasilar Dissecting Aneurysms (METTLE)
Vertebrobasilar dissecting aneurysms (VBDAs) are one of the most important causes of stroke in young and middle-aged people, and the natural history of VBDAs is complex and varied, often leading to high rates of disability and…
- Trial name
- METTLE (NCT06405971)
- Testing
- Metformin
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Ming Lv
Schizophrenia
EEG-based Neurofeedback for Auditory Verbal Hallucinations (HALFEED)
This study's primary objective is to perform a randomized controlled pilot study to assess the feasibility of using EEG-based neurofeedback to reduce the severity of treatment-resistant auditory verbal hallucinations ('hearing…
- Trial name
- HALFEED (NCT03852706)
- Testing
- LORETA, Treatment as usual
- Where
- Ireland
- Volunteers
- 4 people
- Sponsor
- University of Dublin, Trinity College
Insulin Resistance, Postoperative Nausea and Vomiting
Effect of Intravenous 5% Dextrose Infusion During Recovery from Anesthesia on the Quality of Early Postoperative Recovery in Patients Undergoing Painless Gastrointestinal Endoscopy
The aim of this study was to determine the effect of intravenous infusion of 5% dextrose injection during the recovery period of anesthesia for painless gastroenteroscopy on the patient's blood glucose level, incidence of…
- Conditions
- Insulin Resistance, Postoperative Nausea and Vomiting, Quality of Recovery, Dizzyness
- Trial name
- NCT06319144
- Testing
- 5% glucose, 0.9% sodium chloride solution
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Weifang Medical University
Surgical Wound Infection, Traumatic Wound Infection
A Study of Amicidin-β Topical Solution for Patients With a Contaminated or Infected Surgical or Traumatic Wound or Cutaneous Abscess
The goal of this Phase 1 clinical trial is to learn about the safety profile of Amicidin-β topical solution applied directly into contaminated or infected surgical or traumatic wounds or cutaneous abscess during a surgical…
- Conditions
- Surgical Wound Infection, Traumatic Wound Infection, Cutaneous Abscess
- Trial name
- NCT07379684
- Testing
- Amicidin-β topical solution - 15 mL, Amicidin-β topical solution - 50 mL, Standard of Care (SOC)
- Where
- 5 sites in United States
- Volunteers
- 44 people
- Sponsor
- Macro Biologics, Inc.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.