Clinical trials: Resorption
Tooth Loss in the Anterior Maxilla, Alveolar Bone Resorption
Peri-Implant Hard and Soft Tissue Changes After Immediate Implant Placement With Socket Shield and Immediate Restoration Versus Early Implant Placement in the Esthetic Zone
This randomized controlled clinical trial aims to compare peri-implant hard and soft tissue dimensional changes following immediate implant placement with the socket shield technique and immediate restoration versus early type II…
- Conditions
- Tooth Loss in the Anterior Maxilla, Alveolar Bone Resorption, Partial Edentulism of the Maxilla
- Trial name
- NCT07468760
- Testing
- Socket Shield, Early Implant Placement
- Where
- United Arab Emirates
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Alveolar Bone Resorption
Application of Sticky Bone and Bio-Oss Collagen in Alveolar Ridge Preservation
In this experiment, after non-traumatic tooth extraction, the blank group underwent natural healing, and the Bio-Oss Collagen underwent alveolar ridge preservation using Bio-Oss Collagen and the Sticky Bone group using Sticky…
- Trial name
- NCT05902689
- Testing
- alveolar ridge preservation with bio-oss collagen, alveolar ridge preservation with sticky bone
- Where
- China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Alveolar Ridge Augmentation, Bone Substitutes
Alveolar Ridge Preservation (ARP) Study Using Alloplastic Biomaterial and a Resorbable Synthetic Membrane. A Digital Workflow (CBCT/Scanner) Evaluates Hard and Soft Tissue Volumetric Changes at 4 Months, Validating Support for the Gingival Phenotype and Buccal Bone Plate.
The dimensional collapse of the alveolar ridge following tooth extraction represents a critical challenge for implant rehabilitation.
- Conditions
- Alveolar Ridge Augmentation, Bone Substitutes, Guided Tissue Regeneration, Periodontal, Cone-Beam Computed Tomography
- Trial name
- NCT07879495
- Testing
- Alveolar Ridge Preservation using a synthetic alloplastic bone substitute and a resorbable polymer membrane, Minimally invasive flapless tooth extraction followed by unassisted spontaneous healing
- Volunteers
- 28 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Dental Implant, Bone Resorption
Randomized Clinical Study Comparing Two Guided Surgery Techniques for Free-end Implant Placement
This is a randomized multicenter clinical study that compares two static guided surgery techniques in free-end partial edentulism.
- Trial name
- NCT06764654
- Testing
- Dental implant placement
- Where
- 2 sites in Spain
- Volunteers
- 40 people
- Sponsor
- Aula Dental Avanzada
Jaw, Edentulous, Partially, Bone Resorption
Clinical and Radiographic Evaluation of UV-Treated Dental Implants With or Without Melatonin in the Upper Posterior Jaw
The purpose of this study is to evaluate and compare the clinical and radiographic outcomes of using photofunctionalized (UV-treated) dental implants with or without the application of melatonin hormone in the posterior maxilla…
- Conditions
- Jaw, Edentulous, Partially, Bone Resorption, Dental Implant Failure
- Trial name
- UV-MEL-IMPLANT (NCT07853976)
- Testing
- UV-Photofunctionalized Dental Implant, Conventional Dental Implant
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Jaw, Edentulous, Partially, Dental Implant Failure
Densah Bur Versus Modified Conventional Drilling in Early Loaded Maxillary Implants
This study aims to clinically and radiographically evaluate the efficacy of Densah burs (osseodensification) compared to the modified conventional drilling technique for early-loaded dental implants in the posterior maxilla.
- Conditions
- Jaw, Edentulous, Partially, Dental Implant Failure, Bone Resorption
- Trial name
- NCT07850583
- Testing
- Densah Bur Osseodensification, Modified Conventional Drilling
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Mansoura University
Pain, Postoperative, Root Resorption
Evaluation of Different Medicaments in the Management of Necrotic Primary Molars by Lesion Sterilization and Tissue Repair
Management of non-vital primary molars is challenging due to the natural anatomy of primary teeth, patients' young age, and their behavior toward dental treatment.
- Conditions
- Pain, Postoperative, Root Resorption, Persistent Infection, Necrotic Pulp
- Trial name
- NCT06926322
- Testing
- Conventional double antibiotic paste of Metronidazole 500 mg plus Ciprofloxacin 500 mg mixed with propylene glycol, Double antibiotic paste of Metronidazole and Ciprofloxacin loaded chitosan-coated silver nanoparticles, chitosan-coated silver nanoparticles
- Where
- Egypt
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Alveolar Ridge Resorption
Different Approaches for Alveolar Ridge Preservation
Following tooth extraction, physiologic remodeling of the alveolar ridge results in significant horizontal and vertical bone resorption, often accompanied by soft tissue collapse.
- Trial name
- NCT07818447
- Testing
- Bone Allograft + Autologous Platelet-Rich Fibrin (PRF) Membrane, Control group, Bone Allograft + Resorbable Guided Bone Regeneration Membrane
- Where
- Greece
- Volunteers
- 51 people
- Sponsor
- Danae A. Apatzidou
Guided Bone Regeneration, Bone Resorption
The Effect of IPD on Lateral Bone Augmentation
Guided Bone Regeneration (GBR) is a widely used technique during dental implant surgery to help rebuild bone around the implant and improve its long-term appearance and stability.
- Conditions
- Guided Bone Regeneration, Bone Resorption, Diagnostic Imaging
- Trial name
- NCT06999915
- Testing
- Group 1 (Test Group): IP and GBR as an over-contour augmentation beyond IPD, Group 2 (Control Group): IP and GBR as a contour augmentation up to IPD
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- Queen Mary University of London
Physiological Root Resorption of Primary Teeth
The Effect of Physiological Root Resorption in Primary Teeth on the Success of Pulpotomy Treatment
The aim of our study was to evaluate the effect of physiological root resorption on the success of pulpotomy treatment performed using a calcium silicate-based material on primary second molars with deep dentin caries.
- Trial name
- NCT07834814
- Testing
- Pulpotomy treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Aydin Adnan Menderes University
Bone Loss, Osteoclastic, Bone Loss, Alveolar
Autogenous Mesenchymal Stem Cell Culture-Derived Signalling Molecules as Enhancers of Bone Formation in Bone Grafting
This study aims to evaluate bone formation in grafts in terms of its quality (density), quantity (volume) and maturation obtained with the application of a tissue-engineered bone grafting compound containing concentrated…
- Conditions
- Bone Loss, Osteoclastic, Bone Loss, Alveolar, Alveolar Bone Loss, Alveolar Bone Atrophy
- Trial name
- NCT04998058
- Testing
- Maxillary sinus floor elevation grafting with synthetic bone substitute.
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Alveolar Ridge Preservation, Tooth Loss
Volumetric Efficacy of Alveolar Ridge Preservation
The goal of this clinical trial is to compare the effectiveness of four post-extraction socket management approaches in preserving alveolar ridge dimensions following tooth extraction in adults requiring implant-supported…
- Conditions
- Alveolar Ridge Preservation, Tooth Loss, Tooth Extraction, Tooth Extraction Site Healing
- Trial name
- ARP (NCT07812883)
- Testing
- Spontaneous Healing, d-PTFE Membrane, Leukocyte- and Platelet-Rich Fibrin (L-PRF)
- Where
- Chile
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidad del Desarrollo
Tooth Loss
Healing Dynamics in Human Extraction Sockets Grafted With Bio-Oss Collagen®
The purpose of this study is to clinically, radiographically and histologically evaluate the healing sequence of post-extraction sockets grafted with Bio-Oss Collagen® at 3, 6 and 9 months following tooth extraction in…
- Trial name
- NCT03659617
- Testing
- xenograft (BioOss Collagen)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Pain Perception, Root Resorption
The Potential Effect of the Local Administration of Vitamins C and E on Orthodontic Treatment: A Randomized Clinical Trial
Brief Summary of the Study This study investigates the effects of locally administered vitamins C and E on orthodontic tooth movement during the initial stage of treatment.
- Conditions
- Pain Perception, Root Resorption, Rate of Orthodontic Tooth Movement, Biomarkers
- Trial name
- NCT06847880
- Testing
- 1: Vitamin C Supplementation, Vitamin E Supplementation, Saline Solution (Control)
- Where
- 3 sites in Iraq
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Maxillary Deficiency, Bone Resorption
Using Chin Bone Rings for Sinus Lifting and Dental Implants in One Surgery
This study evaluates the Bone Ring Technique, a single stage procedure that combines external sinus floor elevation and dental implant placement using an autogenous bone ring harvested from the chin.
- Trial name
- BRT-SINUS (NCT07619846)
- Testing
- Bone Ring Technique (BRT)
- Where
- Syria
- Volunteers
- 10 people
- Sponsor
- Damascus University
Alveolar Bone Loss, Alveolar Ridge Resorption After Extraction
THBC/CGF for Alveolar Bone Regeneration: A Real-World Study
This study aims to combine real-world research with relevant bone repair materials and techniques to improve alveolar bone resorption in extraction sockets following impacted wisdom tooth removal, while achieving effective bone…
- Conditions
- Alveolar Bone Loss, Alveolar Ridge Resorption After Extraction, Tooth, Impacted
- Trial name
- NCT07779421
- Testing
- Temperature-sensitive hydroxybutyl chitosan-loaded concentrated growth factor, Temperature-sensitive hydroxybutyl chitosan, Autologous Concentrated Growth Factor
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Stomatological Hospital Affiliated with Fujian Medical University
Speed of Alignment, Pain
Comparison of Alignment Speed, Patient Discomfort and Root Resorption Between Two Different Sequences of Archwires
In this Clinical trial we aim to compare alignment speed, patient discomfort and root resorption between two different sequences of NiTi archwires
- Conditions
- Speed of Alignment, Pain, External Root Resorption
- Trial name
- NCT07758556
- Testing
- Archwire
- Where
- 3 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Foundation University Islamabad
Alveolar Bone Resorption
Reducing the Time Interval for Implant Placement After Extraction Socket Preservation Using BIOTECK Materials and OITECH Implant System
This randomized controlled clinical study aims to compare two healing periods (4 vs 6 months) after extraction socket preservation using equine-derived enzymatically treated biomaterials (BIOTECK® system), prior to implant…
- Trial name
- BIO-OI-TECHEIP (NCT07746869)
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Bioteck S.p.A.
Spinal Cord Injury, Spinal Cord Injuries
Testosterone Therapy With or Without Finasteride After Spinal Cord Injury: TRT-SCI Trial
Spinal cord injury (SCI) results in lower limb muscle loss, bone loss, and high fat mass that impede the recovery of physical function, increase bone fracture risk, and worsen health and quality of life.
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Injuries, Spinal Cord, Spinal Cord Contusion
- Trial name
- TRT-SCI (NCT07742553)
- Testing
- testosterone cypionate, finasteride
- Where
- 4 sites in United States
- Volunteers
- 300 people
- Sponsor
- VA Office of Research and Development
Bone Substitutes, Alveolar Bone Grafting
Bone Augmentation Techniques in the Mandible Posterior Region
This study will compare three methods to rebuild lost bone in the back part of the lower jaw (posterior mandible) before dental implant placement.
- Trial name
- NCT06661447
- Testing
- Cortical Shell Bone Grafting
- Where
- Ecuador
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Universidad de Especialidades Espiritu Santo