Clinical trials: Resorption
Alveolar Bone Loss
Localized Alveolar Ridge Augmentation With Dental Implant
The purpose of this research study is to shorten the treatment time course for patients who are scheduled for surgery to have a dental implant(s) placed into the upper front part of their mouths and need to have more bone in…
- Trial name
- RidgeDI (NCT00991965)
- Testing
- INFUSE® Bone Graft
- Where
- 6 sites in United States
- Volunteers
- 8 people
- Sponsor
- Medtronic Spinal and Biologics
Alveolar Bone Loss
Histological Evaluation of Healing Following Ridge Preservation Using a Combined Cortical/Cancellous Mineralized Freeze-Dried Bone Allograft
The study is a 3-arm, parallel-design, randomized, prospective clinical trial.designed to examine histologic wound healing following ridge preservation using cortical bone allograft, cancellous bone allograft, or a combination of…
- Trial name
- NCT02275767
- Testing
- 50% cortical/50% cancellous FDBA, 100% cortical FDBA, 100% cancellous FDBA
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Periodontal Bone Loss
Platelet-rich Fibrin and Autogenous Bone vs Membrane and Autogenous Bone in Intrabony Defects
Currently, the most positive documented outcomes of periodontal regenerative therapy (PRT) in intrabony defects (IBDs) have been achieved with a combination of bone grafts ( BGs) and a regeneration material like membranes in…
- Trial name
- NCT04043754
- Testing
- Procedure/Surgery: Periodontal surgery with Membrane, Periodontal surgery with Platlet Rich fibrin
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Lumbar Intervertebral Disc Displacement, Cervical Intervertebral Disc Displacement
Disc Resorption in Lumbar and Cervical Disc Herniation Patients Receiving Integrative Korean Medicine Treatment
Measurement of herniated disc resorption and assessment of satisfaction regarding post-treatment state and integrative Korean medicine treatment through phone interview in 500 patients with MRI follow-up results receiving…
- Trial name
- NCT02841163
- Testing
- Herbal medicine, Acupuncture, Pharmacopuncture
- Where
- South Korea
- Volunteers
- 505 people
- Sponsor
- Jaseng Medical Foundation
Tooth Loss
Treatment of Post-Extraction Dehisced Socket - A Case Series Study
PURPOSE The purpose of this case series is to clinically, radiographically and histologically evaluate the treatment of dehiscence defects in extraction sockets using a minimally-invasive GBR technique that involves the…
- Trial name
- OSTEO2 (NCT02980211)
- Testing
- Alveolar Ridge Reconstruction
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Gustavo Avila-Ortiz DDS, MS, PhD
Root Resorption
Analysis of Dentine Sialophosphoprotein (DSPP) for Root Resorption
This study was conducted after obtaining approval from UKM Research Ethics Committee. Gingival Crevicular Fluid (GCF) from Orthodontic and non-orthodontic patients was collected with the consent of patients to detect Dentine…
- Trial name
- NCT05077878
- Testing
- DSPP level in GCF
- Where
- Malaysia
- Volunteers
- 30 people
- Sponsor
- National University of Malaysia
Alveolar Bone Loss
Mineralized and Partial Demineralized Dentin Graft Compared to FDBA
The bone grafting materials currently used in dentistry are autografts, allografts, xenografts, and alloplastic grafts. Among these different types of bone graft materials, autografts are considered to have the most predictable…
- Trial name
- NCT05311735
- Testing
- Freeze-Dried Bone Allograft control, Mineralized Dentin Graft, Partial-Demineralized Dentin Graft
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Alveolar Bone Loss, Bone Resorption
Alveolar Management Following Teeth Extraction
Investigation of the volume stability of the alveolar ridge, the bone structure and soft tissue appearance at a delayed dental implantation using two bone substitute materials (1. Human-Spongiosa, gefriergetrocknet, CHB; 2.
- Trial name
- NCT03089619
- Testing
- Human-Spongiosa, collacone®
- Where
- Germany
- Volunteers
- 21 people
- Sponsor
- University Medicine Greifswald
Alveolar Ridge Resorption, Bone Loss in the Esthetic Zone
Clinical and Radiographic Evaluation of CGF and Alloplastic Grafting in Participants Undergoing the Socket Shield Technique for Immediate Anterior Maxillary Implant Placement. This Study Assesses Bone Healing and Stability When Managing the Crestal Gap in the Esthetic Zone.
The goal of this clinical trial is to evaluate the clinical and radiographic effectiveness of the socket shield technique combined with concentrated growth factor (CGF) and alloplastic graft in promoting bone healing and…
- Conditions
- Alveolar Ridge Resorption, Bone Loss in the Esthetic Zone, Socket Shield Technique, Partial Extraction Therapy
- Trial name
- CGF (NCT07514871)
- Testing
- Socket Shield Technique with CGF and Alloplastic Graft.
- Where
- Egypt
- Volunteers
- 7 people
- Sponsor
- Cairo University
Alveolar Process Atrophy
Marginal Bone and Soft Tissue Alterations After Use of OsseoSpeed EV Profile Implants
Evaluation of the marginal bone and soft tissue alterations after the OsseoSpeed™ EV Profile implants placement in anterior maxilla.
- Trial name
- NCT04243421
- Testing
- Implantation
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Tooth Extraction, Bone Graft
Resorbable vs Non-resorbable Bone Substitute at Immediate Post-extractive Single Implants
This study compares two bone graft materials used when placing a dental implant right after tooth removal. One graft fully dissolves (GTO®), the other only partly (Apatos®).
- Conditions
- Tooth Extraction, Bone Graft, Alveolar Bone Loss, Dental Implant
- Trial name
- NCT07047131
- Testing
- GTO® (fully resorbable bone substitute), Apatos® (partially resorbable bone substitute)
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Marco Esposito
Spinal Cord Injuries, Bone Resorption
Bone-biomarkers of Spinal Cord Injury Patients
Patients with spinal cord injury have a high prevalence of osteoporosis due to chronic skeletal unloading. Recently, various treatment drugs for osteoporosis have been developed.
- Conditions
- Spinal Cord Injuries, Bone Resorption, Osteoporosis
- Trial name
- NCT04403256
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Yeungnam University Hospital
CLASS II DIVISION 1 MALOCCLUSION
Root Shortening With Three Different Methods of Upper Anterior Teeth Retraction
External apical root resorption is a possible side effect of fixed orthodontic treatment, particularly in the upper front teeth.
- Trial name
- NCT07906951
- Testing
- Bidimensional Bracket System, Hybrid Dual-Section Archwire, Conventional Sliding Mechanics
- Where
- Syria
- Volunteers
- 60 people
- Sponsor
- Damascus University
Dental Implant, Immediate Implant
Buccal Bone Resorption in Immediate SLActive Implant Placement Thin vs. Thick Buccal Bone
The utilization of SLActive implants which allow more rapid osseointgeration with 3 to 4 weeks. will be placed in thin buccal bone as immediate implants to determine the resorption compared to thick buccal bone
- Trial name
- NCT04731545
- Testing
- immediate implant placement
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Loss, Sinus Floor Augmentation
Two Bovine Xenografts in Lateral Window Sinus Augmentation With or Without Bone Marrow Blood
The goal of this clinical trial is to learn whether adding a small amount of blood taken from the jawbone marrow improves new bone formation when two different bone graft materials are used in maxillary sinus lift surgery.
- Conditions
- Alveolar Bone Loss, Sinus Floor Augmentation, Edentulous Alveolar Ridge
- Trial name
- NCT07904065
- Testing
- Deproteinized Bovine Bone Mineral (Bio-Oss), Deproteinized Bovine Bone Mineral (InterOss), Mandibular Bone Marrow Blood Aspiration
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- Universidad del Desarrollo
Alveolar Bone Grafting
E-Polycaprolactone-Containing Membrane in Alveolar Bone Regeneration
This study aimed to evaluate the effectiveness of synthetic polycaprolactone (PCL) bioscaffold membranes used for alveolar augmentation in maxillofacial surgery for increasing the amount of newly formed bone after…
- Trial name
- NCT06627621
- Testing
- Alveolar Ridge Reconstruction
- Where
- Turkey (Türkiye)
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- cem üngör
Bone Loss, Bone Remodeling Disorder
Socket Preservation Using Dentin Graft Autogenous Dentin Graft With Collagen Sponge on Dental Implant Stability AUTOGENOUS TOOTH GRAFT WITH COLLAGEN SPONGE ON DENTAL IMPLANT STABILITY
The present study was performed to evaluate socket preservation using collagen sponge with autogenous dentin graft versus collagen sponge with de-mineralised freez-dried bone graft on dental implant stability
- Conditions
- Bone Loss, Bone Remodeling Disorder, Bone Resorption
- Trial name
- NCT06853392
- Testing
- Demineralized freeze dried allograft with collagen sponge, autogenous dentin graft with collagen sponge
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Platelet-rich Fibrin, Sinus Floor Augmentation
Maxillary Sinus Augmentation With Xenogeneic Bone Graft Associated or Not With Fibrin Rich in Platelets and Leukocytes Produced by Horizontal Centrifugation: A Randomized Clinical Trial.
The objective of study is to evaluate the influence of the use of Platelet Rich Fibrin (PRF) from the patient's produced by a new horizontal centrifugation protocol associated with particulate xenogenous bone graft in the…
- Conditions
- Platelet-rich Fibrin, Sinus Floor Augmentation, Cone-beam Computed Tomography, Dental Implants
- Trial name
- NCT05957705
- Testing
- Maxilar Sinus augmentation, Dental implant placement using guided surgery
- Where
- Brazil
- Volunteers
- 13 people
- Sponsor
- University of Sao Paulo
Oral Bone Defect, Maxillofacial Bone Defect
Performance and Safety of the Resorbable Collagen Membrane "Ez Cure"
The evaluation of the clinical data has demonstrated the conformity of the Resorbable Collagen Membrane (RCM), EZ CureTM, with the relevant essential requirements for its use in periodontal applications.
- Conditions
- Oral Bone Defect, Maxillofacial Bone Defect, Periodontal Bone Loss, Alveolar Bone Loss
- Trial name
- NCT03978962
- Testing
- Guided Tissue Regeneration
- Where
- 2 sites in France
- Volunteers
- 56 people
- Sponsor
- Biomatlante
Bone Regeneration
Guided Bone Regeneration With L-PRF in the Atrophic Maxilla - The GLAM Technique
16 patients with severe resorbed maxillae referred to Implantology Institute® will be submitted to full arch surgery, with simultaneous implant placement and regeneration in the aesthetic zone, with the GLAM technique.
- Trial name
- NCT03391258
- Testing
- Bone Regeneration with GLAM technique
- Where
- Portugal
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Implantology Institute