Clinical trials: Resorption
Alveolar Bone Resorption, Socket Preservation
Effect of Hyaluronic Acid, With Demineralized Tooth Graft, in Socket Preservation, vs Demineralized Tooth Graft Alone.
Many dentists, clinicians and researchers have conducted numerous trials, and put several materials and procedures under the test, in an attempt to preserve vertical and/or horizontal extraction sockets dimensions.
- Conditions
- Alveolar Bone Resorption, Socket Preservation, Bone Resorption, Unrestorable Dentition
- Trial name
- NCT05613075
- Testing
- tooth extraction and socket preservation with demineralized tooth graft, tooth extraction and socket preservation with demineralized tooth graft with hyaluronic acid
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Implant Failed
Digital Assessment at Peri-implant Tissues After Immediate Implants With Customized Healing Abutments and Connective Tissue Grafts
After a single-tooth extraction, physiological remodeling processes are unavoidable which leads to a total loss of the periodontal ligament and resorption of the bundle bone.
- Trial name
- NCT05060055
- Testing
- Immediate dental implant placement
- Where
- Portugal
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidade Católica Portuguesa
Guided Bone Regeneration, Bone Resorption
The Effect of IPD on Lateral Bone Augmentation
Guided Bone Regeneration (GBR) is a widely used technique during dental implant surgery to help rebuild bone around the implant and improve its long-term appearance and stability.
- Conditions
- Guided Bone Regeneration, Bone Resorption, Diagnostic Imaging
- Trial name
- NCT06999915
- Testing
- Group 1 (Test Group): IP and GBR as an over-contour augmentation beyond IPD, Group 2 (Control Group): IP and GBR as a contour augmentation up to IPD
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- Queen Mary University of London
Alveolar Process Atrophy
Evaluation of a Combined Ridge Expansion Technique With Simultaneous Dental Implant Placement
Patients with long span, narrow edentulous ridge in the posterior mandible underwent piezotomed ridge splitting and osseodensification with simultaneous implant placement.
- Trial name
- NCT05685576
- Testing
- Piezotomed ridge splitting and osseodensification
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Lydia Nabil
Tooth Loss in the Anterior Maxilla, Alveolar Bone Loss* / Therapy
Beta-Tricalcium Phosphate Grafting of Peri-implant Jumping Gaps Greater Than 2 mm in Immediate Implants
This randomized controlled trial evaluated whether grafting the peri-implant "jumping gap" with injectable β-tricalcium phosphate (β-TCP) improves outcomes after immediate implant placement in sites where the horizontal gap…
- Trial name
- NCT07709676
- Testing
- Experimental: Test: beta-tricalcium phosphate grafting
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Minia University
CLASS II DIVISION 1 MALOCCLUSION
Root Shortening With Three Methods of Upper Front Teeth Retraction
External apical root resorption is a possible side effect of fixed orthodontic treatment, particularly in the upper front teeth.
- Trial name
- NCT07744685
- Testing
- Bidimensional Bracket System, Hybrid Dual-Section Archwire, Conventional Sliding Mechanics
- Where
- Syria
- Volunteers
- 60 people
- Sponsor
- Damascus University
Implant Infection, Alveolar Bone Loss
Associations of Alveolar Bone Loss and Interleukin-1β Levels in One and Two Stage Surgical Procedures
The present study was compared the level of alveolar bone loss, clinical parameters and IL-1β in PICF in one- or two-stage surgical procedures.
- Trial name
- NCT03045458
- Testing
- tissue level dental implant, Bone level dental implant
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Firat University
Alveolar Bone Loss, Alveolar Ridge Augmentation
Evaluation of Guided Tissue Regeneration With Autogenous Bone Chips and CGF During Implant Placement
CGF membranes will be prepared using a swing-lock centrifuge. A full-thickness mucoperiosteal flap will be elevated in a narrow alveolar ridge. Implants will be inserted.
- Conditions
- Alveolar Bone Loss, Alveolar Ridge Augmentation, Dental Implant
- Trial name
- CGF (NCT07521514)
- Testing
- concentrated growth factor (CGF) Membrane
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Cairo University
Alveolar Bone Loss
A Feasibility Study for Growth Bone Vertically With Titanium Mesh and Allograft in Lower Posterior Jaw
This study will involve placing donor bone into the back of lower jaw then covering with a newly designed titanium mesh. The mesh will then stay in the mouth for 4 months before it will be removed.
- Trial name
- NCT02255149
- Testing
- Bone/Mesh
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Class II Div 1 Malocclusion
Root Resorption in Class II Div 1 Malocclusion in Upper 1st Premolar Extraction vs Distalization
Rationale: Class II Division 1 malocclusion is characterized by upper anterior teeth protrusion resulting in upper lip protrusion and convex facial profile, which are considered esthetically unfavorable.
- Trial name
- NCT05639725
- Testing
- maxillary Ist premolar extraction, SURGICAL
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Prosthesis Durability
Management of Severely Atrophied Maxillary Ridge Using Quad Zygomatic Implants
This clinical study will aim to compare and evaluate zygomatic implant stability, occlusal contact, and bone level changes around dental implants
- Trial name
- NCT06031506
- Testing
- Implant supported hybrid maxillary prosthesis
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Alveolar Bone Loss, Alveolar Ridge Abnormality
Repeated Injection of I PRF and Autogenous Bone Graft for Alveolar Ridge Augmentation
The current st udy's objective was to validate the repeated effect of i PRF with autogenous bone on the of gingival thickness , width a n d volumetric bone changes durig maxillary alveolar augmentation using cone beam computer…
- Trial name
- I-PRF (NCT06711250)
- Testing
- khoury technique, khoury technique with i-PRF injections
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Atrophic Edentulous Maxilla
Patient-specific Finite Element Analysis of Immediate Loading in the Edentulous Maxilla: Comparison of Three Implant Configurations Using Digital Twins.
Rehabilitation of severely atrophic edentulous maxillae with dental implants pose a significant clinical challenge. Immediate loading in grafted bone is often debated due to concerns about stress distribution and…
- Trial name
- NCT07266896
- Testing
- numerical study
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Laser Therapy, Periodontal Diseases
Odontogenic Graft Obtained From Human Tooth and Low Level Laser Therapy
This clinical trial aims to evaluate the effectiveness of an odontogenic graft obtained from extracted human teeth, with and without adjunctive low-level laser therapy (LLLT), on bone regeneration following posterior tooth…
- Conditions
- Laser Therapy, Periodontal Diseases, Bone Loss in Jaw, Alveolar Bone Loss
- Trial name
- NCT07615361
- Testing
- Autogenous Tooth-Derived Bone Graft, Low-Level Laser Therapy (LLLT)
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Malocclusion, Angle Class II, Division 1
Efficacy of Injectable Platelet Rich Fibrin (i-PRF) in Enhancing Bone Quality
Twenty patients need therapeutic extraction of the maxillary first premolars with subsequent retraction of the maxillary canines, will be divided randomly into two groups, and will randomly assigned to one side of the maxillary…
- Trial name
- NCT03399760
- Testing
- i-PRF, canine retraction
- Where
- Syria
- Volunteers
- 20 people
- Sponsor
- Damascus University
Periodontal Bone Loss
Regenerative Therapy of Periodontal Bone Defects
To compare clinically and radiographically the efficacy of demineralized freeze-dried bone allograft with and without decortication in the treatment of periodontal intrabony defects assessed by gain in clinical attachment…
- Trial name
- NCT03435653
- Testing
- OFD with DFDBA, OFD with decortication and DFDBA
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Alveolar Bone Resorption
Lateral Ridge Augmentation Around Implants
The rehabilitation of dentoalveolar defects and tooth loss has seen remarkable advancements over time. Extraction of tooth leads to reduction in physiologic dimension of bone and it is imperative to evaluate the site before…
- Trial name
- NCT04197128
- Testing
- Resorbable Collagen membrane with bone graft for augmentation, Ribose cross linked collagen matrix for augmentation
- Where
- India
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Periodontal Bone Loss, Periodontal Diseases
Treatment of Intrabony Defects With L-PRF Membrane With or Without Collagen Membranes
For patients having periodontal intrabony lesions, three treatment modalities were executed to evaluate the effect of protecting Leukocyte rich -Platelet Rich Fibrin harvests (applied in the bony defects) with resorbable collagen…
- Trial name
- NCT05496608
- Testing
- L-PRF, OFD, CM
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Alveolar Bone Loss
Demineralized Whole-tooth vs Demineralized Particulate Dentin Grafts in Alveolar Ridge Preservation
The aim of this trial is to compare whole-tooth vs particulate dentin for their effects in alveolar ridge preservation.
- Trial name
- NCT05336149
- Testing
- Alveolar ridge preservation using whole-tooth dentin graft, Alveolar ridge preservation using particulate dentin graft
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Atrophy
Titanium Mesh vs Customized PEEK Mesh for Horizontal Maxillary Ridge Augmentation: A Randomized Clinical Trial
Background: Reconstruction of the deficient maxillary ridge in three dimensions is crucial for the successful placement of implants.
- Trial name
- NCT07002931
- Testing
- Prebent titanium mesh augmentation, Customized PEEK mesh augmentation
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Basma Alsheikh