Clinical trials: Resorption
Alveolar Bone Loss
Pontic Site Development Using Soft Tissue Augmentation
in patients with vertical or horizontal defective of there ridge it is difficult to have prosthetic restoration with natural appearance emetating and simulating the adjacent abutment emergence profile so this study aims to…
- Trial name
- NCT03834649
- Testing
- partially de-epithelized connective tissue graft, Mucograft
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Nouran Abdulla Mater,MD
Dental Caries, Tooth Fractures
Comparison of Conventional and CAD/CAM Dental Restorations
Dental restorations (crowns, inlays or onlays) can be made conventionally or by CAD/CAM. The current literature is weak and does not separate the medical results of these two techniques.
- Conditions
- Dental Caries, Tooth Fractures, Tooth Resorption
- Trial name
- EVACFAOD (NCT02494427)
- Testing
- CAD/CAM manufactured fixed unitary dental prostheses, Conventionally manufactured unitary dental prostheses
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Osteoporosis, Osteopenia
Isoflavones for Promoting Calcium Absorption and Preventing Bone Loss in Post Menopausal Women
Estrogen is a hormone that helps prevent calcium loss and bone breakdown. During menopause, estrogen levels decrease. Insufficient amounts of estrogen may lead to bone loss and possibly osteoporosis.
- Trial name
- NCT00244907
- Testing
- Genistein vs Risedronate
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Purdue University
Periodontal Bone Loss, Periodontitis Stage III
Treatment of Periodontal Intrabony Defects With Liquid Platelet-Rich Fibrin Mixed With Denaturated Albumin Gel (ALB_PRF)
The objective of study also is to assess radiographic linear defect depth, and radiographic defect bone density following the application of liquid Platelet-Rich Fibrin (PRF) mixed with denaturated Albumin gel (ALB-PRF) or with…
- Conditions
- Periodontal Bone Loss, Periodontitis Stage III, Intra-bony Pockets
- Trial name
- ALB-PRF (NCT06798116)
- Testing
- Experimental: open flap debridement and demineralized freeze-dried bone allograft and mixed with liquid (PRF, defects will be treated with open flap debridement and liquid (PRF) mixed with denatured albumin gel (ALB-PRF) will be injected in periodontal intrabony defects, defects will be treated with open flap debridement , DFDBA mixed with liquid (PRF) and collagen membrane
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Mansoura University
Osteoporosis
Thai Traditional Massage Increases Biochemical Marker of Bone Formation in Postmenopausal Women
To investigate the skeletal effect of Thai traditional massage by examining the changes in biochemical markers of bone turnover.
- Trial name
- NCT01627028
- Testing
- Thai traditional massage
- Where
- Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Alveolar Bone Loss
Osseodensification and Ridge Expansion for Implant Placement
Ridge expansion techniques allow implant placement in narrow alveolar ridges by increasing bone volume using the native bone. This technique has shown to be a safe and effective procedure.
- Trial name
- NCT07160309
- Testing
- Densah Bur, Magnetic Mallet
- Where
- Egypt
- Volunteers
- 5 people
- Sponsor
- Al-Azhar University
Alveolar Bone Resorption, Alveolar Ridge Enlargement
Is Cross-linked Hyaluronic Acid a Biologic Alternative for Alveolar Ridge Preservation?
Even after atraumatic tooth removal and/or immediate implant placement, some reduction of the alveolar ridge dimension is expected.
- Conditions
- Alveolar Bone Resorption, Alveolar Ridge Enlargement, Tooth Extraction, Hyaluronic Acid
- Trial name
- NCT07496437
- Testing
- DBBM + FGG, Hyaluronic acid + collagen sponge + FGG
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Periodontal Bone Loss, Periodontal Pocket
Locally Injected Vit D as a Non-surgical Modality for Periodontal Regeneration of Infrabony Defects
vitamin D has great role in bone regenration and soft tissue health. in the past periodontal regeneration was performed using bone graft and barrier membrane
- Trial name
- NCT03716765
- Testing
- locally injected vitamin D
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bone Loss, Alveolar
A Randomized Control Trial Phase (IIIa) Unicentric, Placebo Controlled, Double-Blinded Efficacy and Safety of Topical Alendronic Acid on Alveolar Bone Remodeling After Tooth Extraction
The purpose of the study is to determine the efficacy and safety of the effects of a topical medication on bone remodeling after dental extraction, in order to establish whether such treatment can be a new therapeutic option for…
- Trial name
- XEOLAS (NCT05602493)
- Testing
- Soludronate®, sterile saline
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Xeolas Pharmaceuticals Limited
Alveolar Bone Loss, Tooth Extraction Status Nos
Assessment of Labial Plate Thickness After Immediate Implant Placement Using Two Different Xenografts in the Esthetic Zone
This randomized clinical trial aims to evaluate labial bone plate changes following immediate implant placement in Type II extraction sockets using two different xenograft materials and de-epithelialized free gingival graft in…
- Conditions
- Alveolar Bone Loss, Tooth Extraction Status Nos, Immediate Implant Placement
- Trial name
- NCT07449806
- Testing
- Immediate Implant Placement with Medpark S1 xenograft, Immediate Implant Placement with bio-Oss xenograft
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Basma Gamal Mohamed Ahmed
Atrophic Maxilla, Zygomatic Implants
Dynamic Navigation for Zygomatic Implant Rehabilitation Using an Intraoral Reference System: Evaluation of a New Zygomatic Implant Design
This clinical study aims to evaluate the effectiveness and safety of zygomatic implants placed using dynamic navigation technology.
- Conditions
- Atrophic Maxilla, Zygomatic Implants, Implant Surface
- Trial name
- NAVIZYG-SURF (NCT07124715)
- Testing
- Rough Surface Zygomatic Implant, Partially Machined Surface Zygomatic Implant
- Volunteers
- 22 people
- Sponsor
- University of Bologna
Alveolar Bone Resorption, Horizontal Ridge Deficiency
Computer-guided vs. Conventional Cortical Shell Technique for Horizontal Augmentation
this study aims to evaluate horizontal bone augmentation achieved at the anterior maxilla using computer-guided cortical shell bone technique and accuracy of fixation of the bone shell away from the atrophic ridge by a calculated…
- Trial name
- NCT05311332
- Testing
- Augmentation of horizontal deficient anterior maxilla with a cortical shell harvested from a chin, Augmentation of horizontal deficient anterior maxilla with a cortical shell harvested from a chin using patient specific surgical guide then positioned with another guide
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Teeth Mesial Drift, Bone Injury
Biological Anchorage With Selective Micro-osteoperforations (MOPs) in Canine Distalization
To evaluate the effect of selective micro-osteoperforations (MOPs) on the amount of distal movement of the upper canine, the mesio-distal inclination of the canine and the messiah movement of the upper first molar.
- Conditions
- Teeth Mesial Drift, Bone Injury, Orthodontic Pathological Resorption of External Root
- Trial name
- NCT03741504
- Testing
- micro-osteoperforations (MOPs)
- Where
- 2 sites in Colombia
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Fundación Universitaria CIEO
Xenograft Model
Xenograft and Posterior Mandibular Socket Filling
The aim of this study is to evaluate the volume of madibular bone after placement of a xenograft in a fresh extraction socket in human.
- Trial name
- Flapless (NCT02736773)
- Testing
- xenograft material to slow resorption
- Where
- France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Montpellier
Alveolar Bone Resorption
Socket Shield Technique With or Without Flap Elevation
It is aimed to compare the bone changes and the amount of marginal bone loss after prosthetic loading around the immediately placed implants using the Socket Shield Technique with or without flap elevation.
- Trial name
- NCT05492838
- Testing
- Immediate implantation with the Socket Shield Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Alveolar Bone Loss, Periodontal Attachment Loss
Bone Height and Extractions Study
A coronectomy is often chosen over complete extraction of a lower third molar when the tooth appears to be in close proximity to the inferior dental (ID) canal, as assessed on a plain radiograph or a cone beam computer tomograph…
- Conditions
- Alveolar Bone Loss, Periodontal Attachment Loss, Periodontal Pocket
- Trial name
- NCT03909568
- Testing
- Third molar surgery
- Volunteers
- 50 people
- Sponsor
- King's College London
Periodontal Bone Loss, Chronic Periodontitis
Treatment of Intrabony Periodontal Defects With Enamel Matrix Derivatives and Autogenous Bone Graft
The present study aimed to evaluate the effects of enamel matrix derivatives either alone or combined with autogenous bone graft applied to intrabony defects in chronic periodontitis patients on clinical/radiographic parameters…
- Trial name
- NCT02218515
- Testing
- Open Flap Debridement, EmdogainⓇ(Enamel Matrix Derivative), EmdogainⓇEnamel Matrix Derivative+Autogenous Bone
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Haner Direskeneli, Prof
Rheumatoid Arthritis, Bone Resorption
Differences in Bone Cell Activity Between Rheumatoid Arthritis and Ankylosing Spondylitis
Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are characterized by chronic systemic inflammation and share common pathogenic pathways.
- Conditions
- Rheumatoid Arthritis, Bone Resorption, Ankylosing Spondylitis
- Trial name
- NCT01417455
- Where
- Portugal
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Instituto de Medicina Molecular João Lobo Antunes
Labial Alveolar Bone Thickness, Apical Root Resorption
Labial Alveolar Bone Thickness and Apical Root Resorption Changes Associated With Self-ligating Versus Conventional Brackets
Labial alveolar bone thickness and apical root resorption changes associated with self-ligating versus conventional brackets. The aim of this study will be to compare labial alveolar bone thickness and apical root resorption…
- Trial name
- NCT02816489
- Testing
- Clarity SL MBT brackets; 3M Unitek, Monrovia, CA, USA, Gemini MBT brackets; 3M Unitek, Monrovia, CA, USA
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Alveolar Bone Loss
Effect of Using (PEKK) Framework Versus (Co- Cr) Framework on The Bone of Mandibular Implant Supported Hybrid Prostheses
the purposse of the study To evaluate the effect of implant supported hybrid prostheses on the bone of the supporting structure of edentulous mandible using Polyetherketoneketone (PEKK) framework versus cobalt chromium framework.
- Trial name
- NCT06176014
- Testing
- implant placement
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Ain Shams University