Clinical trials: Resorption
Edentulism, Alveolar Bone Atrophy
The Influence of Dimensional Anatomic Variables on the Outcomes of Maxillary Sinus Grafting Procedures
The hypothesis of this study is that there is a significant difference in bone maturation after sinus grafting determined by the distance from the buccal to the palatal wall of this cavity.
- Conditions
- Edentulism, Alveolar Bone Atrophy, Sinus Pneumatization
- Trial name
- NCT00868777
- Testing
- Sinus grafting using allogenic bone
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Michigan
Alveolar Bone Loss, Bone Deformity
Influence of Mandibular Nerve Lateralization on Nutrition and Speech
This study aimed to evaluate the effects of lip numbness on the nutritional status and speech of patients who underwent inferior nerve lateralization for dental implant placement in the mandibular posterior region.
- Trial name
- NCT05659069
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Marmara University
Alveolar Bone Loss
Graftless Maxillary Sinus Augmentation With CGF Utilizing DIVA System
This study is intended to evaluate the efficiency of graftless maxillary sinus augmentation with concentrated growth factor (CGF) utilizing "dynamic implant valve approach" (DIVA) system.
- Trial name
- NCT02985645
- Testing
- maxillary sinus augmentation with CGF, "dynamic implant valve approach" - DIVA system
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Dental Implant Failed, Platelet-rich Fibrin
Evaluation of Dental Implants Placed in Preserved and Non-preserved Post-extraction Ridges
A prospective study to evaluate and compare implants placed in preserved versus non-preserved extraction sockets using L-PRF (Leucocyte- and platelet-rich fibrin) after 1, 3 and 5 years.
- Conditions
- Dental Implant Failed, Platelet-rich Fibrin, Alveolar Rege Preservation, Alveolar Bone Loss
- Trial name
- NCT03715439
- Testing
- Dental implant
- Where
- 2 sites in Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Peri-implantitis, Alveolar Bone Loss
Diagnostic Accuracy of Large Language Models for Peri-Implant Marginal Bone Loss on Panoramic Radiographs
Dental implants are a routine treatment for missing teeth, but the number of implants affected by peri-implantitis, a progressive inflammatory disease of the tissues around implants, is increasing.
- Conditions
- Peri-implantitis, Alveolar Bone Loss, Dental Implant
- Trial name
- NCT07907900
- Testing
- Multimodal large language model evaluation (ChatGPT, Gemini, Claude, DeepSeek, Grok)
- Where
- Turkey (Türkiye)
- Volunteers
- 784 people, healthy volunteers welcome
- Sponsor
- Ankara University
Alveolar Ridge Augmentation, Bone Substitutes
Alveolar Ridge Preservation (ARP) Study Using Alloplastic Biomaterial and a Resorbable Synthetic Membrane. A Digital Workflow (CBCT/Scanner) Evaluates Hard and Soft Tissue Volumetric Changes at 4 Months, Validating Support for the Gingival Phenotype and Buccal Bone Plate.
The dimensional collapse of the alveolar ridge following tooth extraction represents a critical challenge for implant rehabilitation.
- Conditions
- Alveolar Ridge Augmentation, Bone Substitutes, Guided Tissue Regeneration, Periodontal, Cone-Beam Computed Tomography
- Trial name
- NCT07879495
- Testing
- Alveolar Ridge Preservation using a synthetic alloplastic bone substitute and a resorbable polymer membrane, Minimally invasive flapless tooth extraction followed by unassisted spontaneous healing
- Volunteers
- 28 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Osteoporosis, Prostate Cancer
Effect of Androgen Suppression on Bone Loss in Patients With or Without Bone Metastases Secondary to Prostate Cancer
RATIONALE: Assessing the effect of androgen suppression on bone loss in prostate cancer patients may improve the ability to plan treatment, may decrease the risk of fractures and bony pain, and may help patients live more…
- Trial name
- NCT00003903
- Testing
- management of therapy complications
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Rochester
Alveolar Bone Resorption
Bone Formation Maxillary Sinus Width
According to previous scientific evidence lining on biological concept of bone regeneration into the maxillary sinus, an observational study was set up to record possible (hypothesized) difference in bone formation between…
- Trial name
- NCT04830670
- Testing
- sinus floor elevation with lateral approach
- Where
- 3 sites in Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Atrophy of Edentulous Maxillary Alveolar Ridge, Alveolar Bone Atrophy
Morphological Characteristics of Anterior Maxillary Bone and Dynamic Navigation in Full-Arch Implant Placement
The goal of this clinical trial is to evaluate the effectiveness of dynamic navigation in full-arch dental implant placement in patients with complete maxillary edentulism.
- Trial name
- NCT06974253
- Testing
- Nasopalatine Implants, Trans-Sinus Implants, and Trans-Nasal Implants for Full-Arch Rehabilitation
- Where
- Vietnam
- Volunteers
- 20 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Alveolar Bone Loss, Dental Implant Failed
Linear Micro-Perforation Osteotomy Ridge Split Approach
The traditional ridge split technique might be performed simultaneously with implant placement, resulting in a shortened treatment time.
- Trial name
- LMPO (NCT06887595)
- Testing
- Free-hand linear micro perforation osteotomy and ridge splitting, AI-assisted/computer-guided linear micro perforation osteotomy and ridge splitting
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Alveolar Bone Atrophy
RCT With 3 Different Biomaterials for Maxillary Sinus Lift
Background: Lateral maxillary sinus augmentation (MSA) is a predictable bone regeneration technique in case of atrophy of the posterior-upper maxilla.
- Trial name
- NCT04506827
- Testing
- Maxillary Sinus Augmentation, Maxillary Sinus Graft with ABBM, Maxillary Sinus Graft with TCP
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- University of Pisa
Jaw, Edentulous, Partially, Alveolar Bone Loss
Straumann Bone Ceramic Versus BioOss in Sinus Elevation
Straumann Bone Ceramic (SBC) and BioOss will be used as bone grafting materials when there is a need for bone augmentation in the posterior upper jaw. 9 months later the bone formation is evaluated.
- Trial name
- NCT00900822
- Testing
- Straumann Bone Ceramic, BioOss
- Where
- Sweden
- Volunteers
- 11 people
- Sponsor
- Institut Straumann AG
Alveolar Bone Loss
The Influence of Cortical Bone Perforation on Guided Bone Regeneration in Humans
The purpose of this randomized clinical trial was to evaluate the effect of cortical bone decortication on the angiogenesis and osteogenesis of augmented ridge by GBR.
- Trial name
- NCT02741752
- Testing
- Decortication
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Periodontitis, Dental Caries
Using Combination of Synthetic Bone Substitutes During Extractions
The study was designed to assess the effectiveness of conservation ridge preservation (horizontal and vertical dimension) after tooth extraction with and without combination of bone substitutes based on synthetic (calcium sulfate…
- Conditions
- Periodontitis, Dental Caries, Alveolar Bone Losses
- Trial name
- NCT01503593
- Testing
- Calcium Phosphate, Calcium Sulphate
- Volunteers
- 40 people
- Sponsor
- Rambam Health Care Campus
Osteoporosis, Postmenopausal
Soluble Corn Fiber Effect on Bone Resorption in Post Menopausal Women
This study is designed to study the dose response effect of continuous Soluble Corn Fiber (SCF) intake over a 50 day period on bone resorption in healthy post menopausal women using the 41Calcium methodology.
- Trial name
- NCT02416947
- Testing
- 0 g SCF, 10g SCF, 20g SCF
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Purdue University
Heart Transplantation, Liver Transplantation
Zoledronic Acid Versus Alendronate for Prevention of Bone Loss After Organ Transplantation
The purpose of this study is to compare the effectiveness and safety of zoledronic acid with alendronate in the prevention of bone loss after organ transplantation. Zoledronic acid is given as a single intravenous infusion.
- Conditions
- Heart Transplantation, Liver Transplantation, Bone Resorption
- Trial name
- CTX (NCT00297830)
- Testing
- Zoledronic acid, Alendronate
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- Columbia University
Bone Resorption Disorder
Guided Bone Regeneration in Atrophic Anterior Maxillary Ridges
This study is aiming to evaluate clinically, radiographically ,and histologically GBR using collagen membrane in combination with a mixture of ABBM and autogenous particulated bone compared to collagen membrane with ABBM in…
- Trial name
- NCT03731416
- Testing
- GBR by xenograft and autogenous bone
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession, Bone Loss, Alveolar
Esthetic Outcomes of Single Immediate Implant Placement
A randomized controlled trial of 12-month duration to compare gingival margin location, buccal horizontal ridge dimensions, and interproximal crestal bone levels following two surgical approaches for immediate placement of…
- Trial name
- NCT02435706
- Testing
- Flapless immediate implant placement, Flap assisted immediate implant placement, Implant and temporary crown
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Columbia University
Alveolar Bone Loss
Bone Height Gain Following Transcrestal Sinus Floor Elevation Using Piezoelectric Surgery Versus The Conventional Osteotome Technique
Missing teeth usually result in functional and cosmetic deficits. Traditionally, they have been restored with dentures or fixed bridges.
- Trial name
- NCT03944811
- Testing
- piezoelectric device, Summers technique
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Breast Asymmetry, Fat Atrophy
The Fat Analysis Trial (FAT) - Assessing the Impact of Lipo-aspirate Processing
Fat grafting has been gaining popularity over the past decade. It is now commonly used for breast augmentation and reconstruction, however a major challenge remains the high rate and unpredictable rate of fat resorption…
- Trial name
- NCT05318716
- Testing
- Fat grafting - Revolve device, Fat grafting - Decantation
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's