Clinical trials: Respiration, Artificial
Respiratory Failure, Respiration, Artificial
Proportional Assisted Ventilation and Pressure Support Ventilation in Adult Patients With Prolonged Ventilation
A prospective randomized controlled trial was conducted to collect patients with prolonged mechanical ventilation. Patients were randomly assigned to receive PAV+ or PSV as weaning mode.
- Trial name
- NCT04140682
- Testing
- PAV+ mode, PSV mode
- Where
- Taiwan
- Volunteers
- 44 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Ventilation, Mechanical
Clinical Evaluation of AutoFlow Mode During Mechanical Ventilation
The purpose of this study is to evaluate the long term use of AutoFlow mode during mechanical ventilation in ICU patients
- Trial name
- AFON (NCT00927745)
- Testing
- AutoFlow mode on Evita 4 Dräger ventilators, Evita 4 Dräger ventilators
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Centre Hospitalier Victor Dupouy
Spinal Cord Injuries, Amyotrophic Lateral Sclerosis
Diaphragmatic Pacer Placement: Anesthetic Management (DP)
The diaphragmatic pacemaker (DP) has proven its utility in replacing mechanical ventilation (MV) in patients with chronic spinal cord injury (SCI) and Amyotrophic Lateral Sclerosis (ALS), by improving the patients quality of life…
- Conditions
- Spinal Cord Injuries, Amyotrophic Lateral Sclerosis, Respiratory Paralysis
- Trial name
- DP (NCT02942953)
- Testing
- Diaphragmatic Pacer
- Volunteers
- 16 people
- Sponsor
- Institut Guttmann
Respiration, Artificial, Epidemiology
Mechanical Ventilation Epidemiology in Argentina.
How is the epidemiology of mechanically ventilated patients in the intensive care units of Argentina?
- Trial name
- EpVAr2019 (NCT04107467)
- Where
- 154 sites in Argentina
- Volunteers
- 950 people
- Sponsor
- Argentinian Intensive Care Society
Sepsis, Acute Respiratory Distress Syndrome (ARDS)
Evaluating Artificial Intelligence-Based Clinical Decision Support for Sepsis and ARDS
Sepsis and acute respiratory distress syndrome (ARDS) are common in intensive care units. Managing sepsis and ARDS is inherently complex and requires making numerous decisions under uncertainty.
- Trial name
- NCT07025096
- Testing
- Artifical Intelligence-Generated Treatment Recommendations
- Where
- United States
- Volunteers
- 355 people
- Sponsor
- University of Pennsylvania
Respiratory Distress Syndrome
Sustained Lung Inflation in the Delivery Room in Preterm Infants at High Risk of Respiratory Distress Syndrome
BACKGROUND. Sustained lung inflation (SLI) associated to an adequate PEEP may help the efficacy of the respiratory effort in lung of preterm infants at risk for respiratory distress syndrome (RDS) and reduce need of mechanical…
- Trial name
- SLIS (NCT01440868)
- Testing
- Sustained lung inflation
- Where
- Italy
- Volunteers
- 276 people
- Sponsor
- University of Florence
Respiratory Insufficiency
Respiratory Mechanics and Patient-ventilator Asynchrony Index in Patients With Invasive Mechanical Ventilation
The objective of the study is to estimate the incidence of asynchrony and to assess its relationship with respiratory mechanics. This will be a prospective cohort study, including patients under invasive mechanical ventilation.
- Trial name
- EpiSync (NCT02687802)
- Testing
- mechanical ventilation
- Where
- Brazil
- Volunteers
- 103 people
- Sponsor
- University of Sao Paulo General Hospital
Postmenopausal Period, Postmenopausal Women
AI-Assisted Relaxation and Breathing Training in Postmenopausal Women
This study aims to evaluate the effectiveness of relaxation and breathing training delivered by a physiotherapist and by an artificial intelligence-assisted system in postmenopausal women with non-specific chronic musculoskeletal…
- Trial name
- NCT07302750
- Testing
- Physiotherapist-Guided Relaxation and Breathing Training, Artificial Intelligence-Assisted Relaxation and Breathing Training, Control Group - No Structured Training Program
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Baskent University
Deep Sedation, Respiration, Artificial
Fluid Leakage Past Tracheal Tube Cuff : Effect of Suctioning Manoeuvre
The leakage of oropharyngeal secretions around high-volume low-pressure tracheal tube cuffs is usually considered as a major risk factor for bacterial tracheal colonization and subsequent development of ventilator-associated…
- Trial name
- NCT01170156
- Testing
- Hi-Lo Evac tube (Mallinckrodt Inc, USA) (Instilled blue dye)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Centre Hospitalier de Roanne
Pneumonia, Ventilator-Associated, Critical Illness
Intubation and Extubation Over 48 Hours Mechanical Ventilation
The purpose of this study is to determine how often ventilator associated pneumonia happens in the current intensive care units, and how types of endotracheal tube affect its occurrence.
- Trial name
- INDEX48 (NCT01123681)
- Testing
- Choice of endotracheal tube
- Where
- 6 sites in Japan
- Volunteers
- 200 people
- Sponsor
- Okayama Research Investigator Organizing Network
Delirium, Cognition Disorders
Non-sedation Versus Sedation With a Daily Wake-up Trial in Critically Ill Patients Receiving Me-chanical Ventilation - Effects on Cognitive Function
Through many years, the standard care has been to use continuous sedation of critically ill patients during mechanical ventilation.
- Trial name
- NCT02035436
- Testing
- Non-sedation, Control: Sedation
- Where
- Denmark
- Volunteers
- 205 people
- Sponsor
- Palle Toft
Cardiopulmonary Resuscitation
Pilot Study Comparing Ventilation Modes During CPR With Mechanical Compression Device.
Comparison of three ventilation modes (volume controlled, BIPAP and CPAP) during cardiopulmonary re-suscitation with a mechanical compression device in the emergency room.
- Trial name
- COVME (NCT03347175)
- Testing
- Volume controlled ventilation, Pressure controlled ventilation, CPAP mode
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Technical University of Munich
Selenium Level
Effect of Heart-lung-machine on Selenium Status of Cardiac Surgical Patients Undergoing Coronary Bypass Surgery
Since selenium has demonstrated significant characteristics for a series of biochemical processes, for antioxidant activity and immune stimulation, this observational study should represent the effect of heart-lung-machine on…
- Trial name
- SEOPCAB (NCT01409057)
- Where
- Germany
- Volunteers
- 46 people
- Sponsor
- RWTH Aachen University
Respiration, Artificial, Acute Hypoxemic Respiratory Failure
Adherence to Low Tidal Volume in the Transition to Spontaneous Ventilation in Patients With Acute Respiratory Failure
The goal of this observational study is to estimate the prevalence of the use of protective ventilation with low tidal volume ventilation in the transition of spontaneous ventilation modes in patients with hypoxemic acute…
- Conditions
- Respiration, Artificial, Acute Hypoxemic Respiratory Failure, Respiratory Insufficiency
- Trial name
- SPIRAL (NCT06042036)
- Testing
- Spontaneous mode of mechanical ventilation
- Where
- 10 sites in Argentina, Bolivia and 8 more
- Volunteers
- 431 people
- Sponsor
- University of Sao Paulo General Hospital
Respiratory Disease, Artificial Respiration
Non-invasive Assessment of Inspiratory Effort and Tidal Distension During Non-invasive Ventilation (INSPIRE)
The goal of this observational study is to evaluate whether the airway occlusion pressure recorded during a sudden end-expiratory breath-hold (ΔPocc) is correlated with esophageal swing in pressure and the reliability of P0.1…
- Trial name
- INSPIRE (NCT06344234)
- Testing
- End-inspiratory Maneuvers
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Bari
Respiration, Artificial
Use of a New Isokinetic Device for Inspiratory Muscle Training
Introduction: It is well established that physical fitness improves muscle performance either in sedentary people or in athletes.
- Trial name
- NCT02932189
- Testing
- Inspiratory muscle training
- Where
- Brazil
- Volunteers
- 102 people
- Sponsor
- Universidade Federal Fluminense
Artificial Respiration, Consciousness Disorders
Evaluation of a New Mechanical Ventilation Weaning Strategy for Patients With Altered Level of Consciousness
The purpose of this study is to determine if a weaning strategy from artificial ventilation governs by respiratory behaviour status assessed by our method is safe enough.
- Conditions
- Artificial Respiration, Consciousness Disorders, Wearing Off Effect
- Trial name
- ORGAR (NCT00700869)
- Testing
- mechanical ventilation
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infections Associated With Mechanical Ventilation, Pneumonia Associated With Mechanical Ventilation
Efficacy of Mouth-rinse With Chlorhexidine for the Prevention of Ventilator-associated Infections in Intensive Care Unit
Background: Infections associated with mechanical ventilation are associated with high rates of morbidity and mortality, which results not only in an increase in hospitalization days and care costs, but also in an increase in…
- Trial name
- NCT04165356
- Testing
- Mouth-rinse with 0.12% clorhexidine, Mouth-rinse with isotonic solution with 1.5% sodium bicarbonate
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- Universidad Autónoma de Yucatán
Respiratory Failure (Pediatric Patients), Pneumonia
AI-Assisted Bronchoscopy Navigation and Diagnostic System for Severe Pneumonia: A Multicenter Prospective Study
This study will evaluate an embodied-intelligence-assisted bronchoscopy navigation and diagnostic system for patients with severe pneumonia who require clinically indicated bronchoscopy.
- Trial name
- EIBRONCH (NCT07230431)
- Testing
- Embodied-Intelligence-Assisted Bronchoscopy Navigation and Diagnostic System (EIBRONCH), Conventional Bronchoscopy (Standard of Care)
- Volunteers
- 100 people
- Sponsor
- Chinese Medical Association
Anesthesia, General/Methods, Laparoscopy
Transpulmonary Driving Pressure and Intra-abdominal Pressure Relationship During Laparoscopic Surgery
Objective: The aim of this project is to evaluate how intra-abdominal pressure paired coupled with different ventilatory positive end-expiratory pressure levels affects the transpulmonary driving pressure during pneumoperiteneum…
- Conditions
- Anesthesia, General/Methods, Laparoscopy, Respiration, Artificial, Positive-Pressure Respiration
- Trial name
- NCT03435913
- Testing
- Standard PEEP ventilation, Matched PEEP ventilation
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Hospital Universitario La Fe