Clinical trials: Respiratory Allergy
Asthma, COPD
Exhaled Breath Metabolomic Biomarkers in the Acutely Breathless Patient
An acute study carried out across three acute admissions units within Leicestershire. The study is aimed at discovery and validation of volatile organic compounds (VOCs) in exhaled breath.
- Conditions
- Asthma, COPD, Heart Failure, Community-acquired Pneumonia
- Trial name
- EMBER (NCT03672994)
- Where
- United Kingdom
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Asthma
The Effect of Long Term Inhaled Corticosteroids on the Risk of Cardiovascular Morbidities
Cardiovascular disease is a major cause of morbidity and mortality worldwide. It is the second leading cause of death in Hong Kong. The disease burden is huge and effective control measures should target at prevention level.
- Trial name
- NCT00959257
- Where
- 4 sites in Hong Kong
- Volunteers
- 1,394 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Asthma
Clinical Pharmacology Study to Evaluate the Total Systemic Exposure and Lung Bioavailability of CHF 5993 pMDI Combination in Healthy Volunteers
The study is performed to evaluate the total systemic exposure and lung bioavailability of CHF 5993 pMDI combination, in healthy volunteers subjects.
- Trial name
- NCT02359292
- Testing
- CHF 5993 HS 200/6/25 pMDI, CHF 5993 MS 100/6/25 pMDI, CHF 5993 HS 200/6/25 pMDI + Charcoal Block
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chiesi Farmaceutici S.p.A.
Asthma, Children
Asthma Action at Erie Trial
The Asthma Action at Erie Trial compares the current best practice in asthma self-management education (certified asthma educator services) to an integrated community health worker (CHW) home intervention in which the real-life…
- Trial name
- NCT02481986
- Testing
- Community Health Worker, Certified asthma educator
- Where
- United States
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Asthma
Effect of Benralizumab on Airway Remodeling in Asthma
The anti-interleukin (IL)-5 receptor benralizumab inhibits eosinophilic inflammation but its potential effect on airway remodeling remains unknown.
- Trial name
- BENRAMOD (NCT04365205)
- Testing
- Endobronchial biopsy
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Asthma, Chronic Obstructive Pulmonary Disease
Trial Comparing Effect of He/O2 to Medical Air on Pulmonary Function Disease
This clinical trial will include healthy volunteers, COPD patients and asthmatic patients who will breathe He/O2 78:22, He/O2 65:35 and medical air consecutively in a randomised order.
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease, Healthy
- Trial name
- NCT00801307
- Testing
- spirometer
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Air Liquide SA
Bronchial Asthma
Study on the Treatment of Bronchial Asthma With Traditional Chinese Medicine
The purpose of this study is to evaluate the clinical efficacy of traditional Chinese medicine in the treatment of asthma, and to promote the application in community hospitals.
- Trial name
- NCT02937207
- Testing
- Ke Chuan Liu Wei Mixture, Chuan Xiong Ping Chuan Mixture, Xie Wu Capsule
- Where
- 5 sites in China
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Allergic Rhinitis
Integrative Omics Approach to Allergic Rhinitis
Nasal mucus and nasal epithelium are the first defense barriers against allergens. Various proteins are found in nasal mucus that play a role in allergic rhinitis and reflect immune response to allergen exposure.
- Trial name
- IntegOmics (NCT03324100)
- Where
- Austria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Asthma
The Asthma Bronchial Challenge Study
This is a randomised, controlled, cross-over study to determine the effect of indirect bronchial challenge testing upon volatile organic compounds (VOCs) in the exhaled breath of adults with well-controlled, mild-to-moderate…
- Trial name
- ABC (NCT03575663)
- Testing
- Indirect bronchial challenge
- Where
- United Kingdom
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Asthma, COPD
A Bioequivalence Pivotal Study of SYN010 HFA Inhaler and Symbicort® 160/4.5 in Healthy Volunteers Without Charcoal Block
The objective of this pivotal study is to evaluate the relative bioavailability of SYN010 HFA Inhaler and Symbicort 160/4.5μg in healthy volunteers without charcoal block.
- Trial name
- NCT04494321
- Testing
- Budesonide, Formoterol
- Where
- Taiwan
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Intech Biopharm Ltd.
SARS-CoV-2 Infection, SARS-CoV-2 Vaccination
Validation of 'Corona-T-test' for Assessment of SARS-COV-2-specific T-cell Response After COVID-19 or Vaccination
Accuracy validation of the designed and manufactured ELISpot-based in vitro diagnostic 'Corona-T-test' for detection of SARS-CoV-2-specific T cells.
- Trial name
- NCT05165719
- Testing
- Corona-T-test
- Where
- Russia
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- National Research Center for Hematology, Russia
Asthma
Safety and Pharmacokinetics of Halix(TM) Albuterol Unit Dose Disposable Inhaler Versus Albuterol MDI
Healthy male and female volunteers without asthma will be recruited to enroll in a single dose 3-way crossover study of the safety and pharmacokinetics of albuterol when administered using the Halix (TM) albuterol unit dose…
- Trial name
- NCT03373409
- Testing
- Albuterol DPI 90mcg, Albuterol DPI 180mcg, Albuterol HFA MDI
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Concentrx Pharmaceuticals, Inc.
Asthma
Relovair PD PK in Chinese Healthy Subjects
In this study, fluticasone furoate (FF) and vilanterol (VI) in different dose combinations (50/25mcg, 100/25mcg and 200/25mcg) will be administered from a single dry powder device to evaluate the PD, PK, safety and tolerability…
- Trial name
- NCT01711463
- Testing
- Fluticasone Furoate/Vilanterol
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Asthma, COPD
The Effects of Broccoli Sprout Extract on Obstructive Lung Disease
The purpose of this study is to examine whether broccoli sprout extract can effect lung function measurements in individuals with asthma and COPD.
- Trial name
- NCT00994604
- Testing
- broccoli sprout extract
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Healthy Participants
A Study to Investigate the Relative Bioavailability of AZD8630 Following a Device and Formulation Transition in Healthy Participants.
The purpose of this study is to evaluate the potential difference between pharmacokinetics (PK), safety, tolerability and device performance between the AZD8630 test formulation and the AZD8630 reference formulation.
- Trial name
- NCT06531811
- Testing
- AZD8630 (test formulation) via test inhaler, AZD8630 (reference formulation) via Monodose inhaler, Test inhaler
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Asthma, COPD
Sputum and Plasma Levels of Nociceptin and Substance P in Patients With Asthma, COPD and Chronic Cough
The aims of this study are to investigate the association between sputum and plasma levels of nociceptin and substance P with cough severity and airway hyperreactivity in patients with asthma, COPD and chronic cough.
- Conditions
- Asthma, COPD, Cough
- Trial name
- NCT00173225
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Sleep Apnea, Asthma
Sleepiz One+ vs. Capnography and Electrocardiography
Respiratory Rate (RR) and heart rate (HR) are vital signs crucial for assessing a patient's overall health, providing insights into various conditions and stressors.
- Conditions
- Sleep Apnea, Asthma, COPD, Hypertension
- Trial name
- NCT06569940
- Testing
- Sleepiz One+
- Where
- Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Sleepiz AG
Asthma, Health Personnel
Changes in Physician Performance Through Continuous Professional Development
The purpose of this study is to determine whether having physicians evaluate their management of certain diseases as part of board recertification results in improved patient care.
- Trial name
- NCT00115284
- Testing
- ABIM asthma practice improvement module
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention, Heart Disease
Social Work Intervention Focused on Transitions
In response to Program Announcement (PA)-09-164, "NIH Exploratory/Developmental Research Grant Program (R21) a randomized pilot study testing the efficacy of SWIFT: Social Work Intervention Focused on Transitions among at-risk…
- Conditions
- Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention, Heart Disease, Diabetes, Hypertension
- Trial name
- SWIFT (NCT02232126)
- Testing
- SWIFT home intervention
- Where
- 2 sites in United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Chronic Obstructive Pulmonary Disease (COPD), Asthma (Diagnosis)
Construction and Validation of an Impulse Oscillometry (IOS)-Based Platform for Screening, Diagnosis, and Management of Chronic Airway Diseases
This is a multicenter, observational study aiming to construct and validate an Impulse Oscillometry (IOS)-based platform for the screening, diagnosis, and management of chronic airway diseases (COPD and asthma).
- Trial name
- NCT07910409
- Where
- China
- Volunteers
- 2,800 people, healthy volunteers welcome
- Sponsor
- Beijing Chao Yang Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.