Clinical trials: Respiratory Allergy
Allergic Rhinitis
Implementation of an Allergic Rhinitis Severity Questionnaire in ENT Consultations
Allergic rhinitis is a very common condition (affecting 1 in 5 people in Europe) and a costly one for society (direct and indirect costs).
- Trial name
- QSRA-ORL (NCT07315945)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Asthma, Obesity
The Childhood Health and Asthma Management Program
Overweight and obese (OV/OB) children with asthma are at-risk for particularly poor health outcomes including poor asthma control, higher risk of asthma-related symptoms, and decreased quality of life.
- Conditions
- Asthma, Obesity, Family, Child
- Trial name
- CHAMP (NCT02303561)
- Testing
- CHAMP, Health education
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Florida
Rhinitis, Allergic, Rhinoconjunctivitis
Efficacy and Safety Evaluation for the Treatment of Allergy Against Grass and Olive Pollen
Prospective, multicenter, randomized, double-blind, placebo-controlled clinical trial of efficacy and safety with subcutaneous immunotherapy in patients with mild to moderate rhinitis / rhinoconjunctivitis with or without mild to…
- Conditions
- Rhinitis, Allergic, Rhinoconjunctivitis, Asthma, Allergic
- Trial name
- NCT04891237
- Testing
- 10,000 MG01 + 10,000 T517, 30,000 MG01 + 10,000 T517
- Where
- 32 sites in Spain
- Volunteers
- 180 people
- Sponsor
- Inmunotek S.L.
Asthma, Allergic Asthma
Asthma Inflammation Research
The overall goal of the Asthma Inflammation Research [AIR] Translational Program is to create an integrated multidisciplinary team for the focused purpose of development of diagnostic and prognostic tests informative for airway…
- Conditions
- Asthma, Allergic Asthma, Non-allergic Asthma
- Trial name
- AIR (NCT01536522)
- Testing
- Nutritional approach for asthma, Low Caloric Shake, whole lung allergen challenge
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Asthma
Environmental Intervention to Reduce Allergens in Urban Schools and Childhood Asthma
The investigators aim to pilot the role of school based intervention consisting of enhanced integrated pest management, classroom air purifiers and cleaning improves asthma morbidity.
- Trial name
- NCT01913795
- Testing
- integrated pest management, air purifier
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Asthma in Children
Effect of a Daily Text Reminder on Asthma Medication Use, Symptom Control, and Lung Function in Children
The goal of this clinical trial is to learn if a daily text reminder ("AdhasText") can help children with asthma use their inhalers regularly, control their symptoms, and improve their lung function.
- Trial name
- NCT07053839
- Testing
- Daily Text Reminder
- Where
- Peru
- Volunteers
- 64 people
- Sponsor
- ROXANA AZNARAN TORRES
Asthma
Role of Cigarette Smoking in Regulating Allergen-induced Early and Late Responses in Mild Asthmatics
The objective of this study is to determine the effect of cigarette smoking on inflammatory cell recruitment to the lungs after an allergen challenge, in non-smoking and currently smoking mild asthmatic subjects.
- Trial name
- NCT00626171
- Testing
- Allergen Challenge
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Hamilton Health Sciences Corporation
Preschool Severe Asthma
Preschool Bronchial Remodeling and Risk of Exacerbation
Bronchial remodeling is an abnormal tissue repair process of the bronchial wall components that characterizes severe asthma which can include epithelial abrasion, thickening of the reticular basement membrane (RBM), an increase…
- Trial name
- RESPIRE (NCT04558671)
- Testing
- asthma exacerbations
- Where
- 2 sites in France
- Volunteers
- 56 people
- Sponsor
- University Hospital, Bordeaux
Extrinsic Allergic Alveolitis
Bronchoalveolar Immune Response Determination
The purpose of this study is to establish if cells present in lung tissue during extrinsic allergic alveolitis (EAA) are able to elicit an immune response against specific antigens.
- Trial name
- BIRD (NCT01237145)
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Bossink, A.W.J.
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Effectiveness of Interventions to Teach Respiratory Inhaler Technique (E-TRaIN)
The purpose of this study is to evaluate the relative effectiveness of two different ways to teach subjects while hospitalized how to use respiratory inhalers and to follow-up after discharge home from the hospital to determine…
- Trial name
- E-TRaIN (NCT01426581)
- Testing
- Teach-To-Goal, Brief Intervention
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Chicago
Asthma
Real Life Effectiveness of Easyhaler (Orion)
The aim of this study is to compare the clinical effectiveness and cost-effectiveness of the Easyhaler® (EH) device and other DPI devices commonly used in the UK in a UK primary care asthma population of patients aged 6 to 80…
- Trial name
- NCT02048930
- Testing
- Budesonide Easyhaler, Budesonide dry powder inhaler
- Volunteers
- 24,003 people
- Sponsor
- Research in Real-Life Ltd
Rhinitis, Allergic, Perennial
Comparator Study Evaluating Patient Experience And Preference Of FFNS vs. FPNS
The purpose of this replicate study to FFU105924 is to provide data on subject preference of FFNS as compared with FPNS.
- Trial name
- NCT00519636
- Testing
- FPNS, FFNS
- Where
- 28 sites in United States
- Volunteers
- 360 people
- Sponsor
- GlaxoSmithKline
Asthma
A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With Asthma
The primary purpose of this study is to evaluate the effects of Fluticasone Furoate (FF)/ Umeclidinium (UMEC)/ Vilanterol (VI) on lung function compared with FF/VI after 24 weeks of treatment.
- Trial name
- NCT05757102
- Testing
- FF/UMEC/VI, ELLIPTA, FF/VI
- Where
- 67 sites in United States, Argentina and 7 more
- Volunteers
- 138 people
- Sponsor
- GlaxoSmithKline
Asthma, Asthma Attack
Optimisation of ASthma In Those With Uncontrolled Symptoms (OASIS)
A digital tool, called ReferID has been developed to facilitate the review of asthma patients. It aims to assist in the identification of patients with uncontrolled and/or severe asthma and to ensure a timely referral to…
- Conditions
- Asthma, Asthma Attack, Asthma Persistent, Covid19
- Trial name
- OASIS (NCT04941001)
- Testing
- ReferID
- Where
- United Kingdom
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Asthma
A Pilot Study Involving an Asthma Management Program for Inner-city Early Head Start Children
The Early Head Start program serves lower socioeconomic inner-city children from birth to 3 years. This population has a higher incidence of asthma due to increased exposures.
- Trial name
- NCT00624429
- Testing
- Budesonide respules
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Phoenix Children's Hospital
Asthma
Effectiveness of the Pelican Instrument in Medical Care
The objective of this project is to establish the effectiveness of implementation of a self-administered electronic asthma-specific quality of life instrument for childhood asthma in primary care and specialist care.
- Trial name
- PELICANII (NCT01109745)
- Testing
- PELICAN Primary Care, PELICAN Secondary Care
- Where
- 6 sites in Netherlands
- Volunteers
- 120 people
- Sponsor
- Radboud University Medical Center
Uncontrolled Asthma
A Phase 3 Study to Evaluate the Efficacy and Safety of Tralokinumab in Adults and Adolescents With Uncontrolled Asthma
A 52-Week, Multicentre, Randomized, Double-Blind, Parallel Group, Placebo Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Tralokinumab in Adults and Adolescents with Asthma Inadequately Controlled on Inhaled…
- Trial name
- STRATOS1 (NCT02161757)
- Testing
- Tralokinumab
- Where
- 243 sites in United States, Argentina and 13 more
- Volunteers
- 1,207 people
- Sponsor
- AstraZeneca
Asthma
Asthma Learning Project
The purpose of this study is to determine the effect on knowledge and behavior of playing an educational asthma computer game during a pediatric Emergency Department (ED) asthma visit among children ages 7 - 15 years.
- Trial name
- ALP (NCT00874900)
- Testing
- Educational game, Educational game + motivational interview, Motivational interview
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Seattle Children's Hospital
Rhinitis, Allergic, Perennial
A Study of GW685698X for the Treatment Of Perennial Allergic Rhinitis in Adolescents and Adults
The purpose of this study is to assess the effect of an aqueous nasal spray investigational compound compared to placebo on the hypothalamic pituitary adrenocortical (HPA) axis system in adolescents and adults 12 to 65 years of…
- Trial name
- NCT00116818
- Testing
- GW685698X aqueous nasal spray
- Where
- 2 sites in United States, Canada
- Volunteers
- 90 people
- Sponsor
- GlaxoSmithKline
Asthma
Role of T-Cells in Asthma
This study will examine the movement of T cells (a type of white blood cell) from the blood to the lungs in patients with asthma after exposure to an allergen, such as cat dander or pollen.
- Trial name
- NCT00001408
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
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