Clinical trials: Respiratory Aspiration
Aerobic and Breathing Exercises in Pregnant Women
Blood Oxygenation and Exercises in Pregnant Women
To investigate the blood oxygenation response to aerobic and breathing exercises in pregnant women. Participants and methods: A total of forty pregnant women participated in the study who were at the beginning of 3rd trimester.
- Trial name
- exercises (NCT04077931)
- Testing
- exercises
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bronchiolitis Obliterans, Sleep Disordered Breathing Central
Sleep Disorders in Bronchiolitis Obliterans Syndrome 2&3
This study is to determine whether sleep disorders contribute to impaired quality of life and mobility in patients with Bronchiolitis Obliterans syndrome and whether non invasive positive airways pressure ventilation can improve…
- Trial name
- NCT02109237
- Testing
- Assessment of sleep disorders and treatment if required
- Where
- Australia
- Sponsor
- The Prince Charles Hospital
Prematurity, Respiratory Distress Syndrome, Newborn
Will CPAP Reduce Length Of Respiratory Support In Premature Infants?
In Canada each year, there are approximately 800 infants born between 28 and 32 weeks gestation. Up to 60% of these infants will require breathing tube placement for Respiratory Distress Syndrome or RDS.
- Trial name
- OLIVIA (NCT00486395)
- Testing
- CPAP, Mechanical ventilation
- Where
- 6 sites in Canada
- Volunteers
- 126 people
- Sponsor
- Children's & Women's Health Centre of British Columbia
Autism
Self-inspired & Tailored Autism Movement With Phystic App
The goal of this clinical trial is to learn if watching instructions for daily exercises with three different contents (the patients themselves, other children, or children dressed as rabbits in addition to their physiotherapist…
- Trial name
- STAMP (NCT07485439)
- Testing
- Exercise
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Linkoeping University
Fospropofol Disodium
Effects of Fospropofol Disodium TIVA and IVIH on Surgical Field Quality in Adult ESS
Endoscopic sinus surgery (ESS) is a primary surgical approach for treating chronic rhinosinusitis, nasal polyps, and other conditions that are unresponsive to conservative therapy.
- Trial name
- NCT07788157
- Testing
- Fospropofol disodium, Propofol
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Tongji Hospital
Noninvasive Ventilation
Effect of Head Rotation on Efficacy of Face Mask Ventilation in Anesthetized Obese (BMI ≥ 35) Adults
Mask ventilation is fundamental to airway management at the start of surgical procedures requiring general anesthesia. For general anesthesia, medications are provided that affect the entire body and lead to a loss of…
- Trial name
- NCT03876873
- Testing
- Head Rotation During Face Mask Ventilation, Medline Top Valve Anesthesia Mask
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Missouri-Columbia
Extubation Failure
Performance of the Variation in Arterial Lactatemia During a Spontaneous Breathing Trial (SBT) in the Prediction of Extubation Failure
Extubation failure (EF) is independently associated with excess mortality of critically ill patients. To avoid EF, critically ill patients being weaned from invasive mechanical ventilation (IMV) perform spontaneous breathing…
- Trial name
- PREDILACT (NCT05487573)
- Where
- France
- Volunteers
- 242 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
High Flow Oxygen Therapy, ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION
High-Flow Nasal Oxygyen Therapy During Sedated Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration(EBUS-TBNA)
This study aims to evaluate the effects of high-flow nasal oxygen therapy on respiratory complications, blood gas parameters, and post-procedural recovery in patients undergoing sedated endobronchial ultrasound-guided…
- Conditions
- High Flow Oxygen Therapy, ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION, Sedation, Sedation Complication
- Trial name
- NCT07760727
- Testing
- High-Flow Nasal Oxygen Therapy, Conventional Oxygen Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Pulmonary Disease, Chronic Obstructive
Safety and Efficacy of BI 1744 CL in Patients With Chronic Obstructive Pulmonary Disease I
The primary objective of this study is to assess the long-term efficacy and safety of once daily treatment of BI 1744 CL inhalation solution (5 and 10 mcg) delivered via the Respimat® inhaler, in patients with COPD.
- Trial name
- NCT00793624
- Testing
- Olodaterol (BI 1744), Formoterol
- Where
- 93 sites in Argentina, Brazil and 18 more
- Volunteers
- 906 people
- Sponsor
- Boehringer Ingelheim
COPD (Chronic Obstructive Pulmonary Disease)
Inhaled Treprostinil for Dyspnea and Exercise Intolerance in Mild COPD
The goal of this clinical trial is to evaluate the impact of inhaled Treprostinil on breathlessness and low exercise capacity in patients living with mild chronic obstructive pulmonary disease.
- Trial name
- NCT06969573
- Testing
- Treprostinil Inhalation Solution 36 mcg, Treprostinil Inhalation Solution 78 mcg
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Bronchial Asthma
Safety, Tolerability, and Pharmacokinetics of PA9159 Inhalation Aerosol in Healthy Adult Subjects
PA9159 is a highly potent novel corticosteroid. The purpose of this study is to exam the safety, tolerability, and pharmacokinetics of single and repeat dosing of Inhalation aerosol PA9159, to establish maximum tolerated dose in…
- Trial name
- NCT06916273
- Testing
- PA9159 Inhalation aerosol, 60 μg one day treatment, PA9159 Inhalation aerosol, 120 μg one day treatment, PA9159 Inhalation aerosol, 240 μg one day treatment
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Anhui Palo Alto Pharmaceuticals, Inc.
Respiratory Function
Effect of a Respiratory Training Program on Woodwind and Brass Players
This project will study the effect of a respiratory training program on woodwind and brass players, using an inspiratory muscle training equipment.
- Trial name
- NCT06175286
- Testing
- POWERBreath Plus Medium Resistance training device
- Where
- Portugal
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aveiro University
Adherence, Treatment
Standard Operating Procedure As a Valuable Tool to Increase Adherence to Lung Protective Ventilation Among Anesthesiologists.
Lung Protective Ventilation (LPV) is considered the gold standard of care nowadays. Even though, all over the world reported adherence to this concept, among anesthesiologists, is only 15%.
- Trial name
- NCT05831683
- Testing
- Introduction of Standard Operating Procedure regarding lung protective ventilation during general anaesthesia.
- Where
- Czechia
- Volunteers
- 164 people
- Sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
Hyperemesis Gravidarum
The Effect of Guided Imagery and Diaphragmatic Breathing Exercise in Pregnant Women With Hyperemesis Gravidarum
Objective: The aim of the researchers is to determine the effects of guided imagery and diaphragmatic breathing exercise application on nausea, vomiting severity, and anxiety level in pregnant with hyperemesis gravidarum.
- Trial name
- NCT05829473
- Testing
- Breathing Exercise Group, Guided Imagery Group
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Gaziantep Islam Science and Technology University
Asthma
A Study Testing the Superiority of CHF 1535 pMDI 800/24µg Total Daily Dose Compared With CHF 718 pMDI 800µg Total Daily Dose in Adults With Asthma on Medium or High-Dose Inhaled Corticosteroid
Compare the superiority of CHF 1535 versus CHF 718 in subjects with asthma who are on medium or high dose inhaled corticosteroids.
- Trial name
- FORCE2 (NCT05292586)
- Testing
- Beclomethasone Dipropionate/Formoterol Fumarate, Beclomethasone Dipropionate
- Where
- 91 sites in United States
- Volunteers
- 1,377 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Infant, Newborn, Hypertension, Pulmonary
Early Inhaled Nitric Oxide for Respiratory Failure in Newborns
This prospective, randomized controlled trial tested whether initiating iNO therapy earlier would reduce death and reduce the use of extracorporeal membrane oxygenation (ECMO) -- temporary lung bypass -- therapy compared with the…
- Conditions
- Infant, Newborn, Hypertension, Pulmonary, Persistent Fetal Circulation Syndrome, Pneumonia, Aspiration
- Trial name
- Early iNO (NCT00005773)
- Testing
- Inhaled Nitric Oxide, Standard iNO therapy
- Where
- 18 sites in United States
- Volunteers
- 302 people
- Sponsor
- NICHD Neonatal Research Network
Coronary Artery, Anxiety
The Effect of Diaphragmatic Breathing Exercise on Symptom Severity, Sleep Quality and Anxiety in CABG Patients.
Coronary artery bypass surgery (CABC) is a commonly performed surgical procedure for the treatment of blockages in the heart vessels. This surgical intervention aims to improve the blood circulation of the patients' heart muscle.
- Conditions
- Coronary Artery, Anxiety, Symptom, Sleep
- Trial name
- NCT06356896
- Testing
- diaphragmatic breathing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- KTO Karatay University
Acute Hypoxemic Respiratory Failure
High-Frequency Oscillatory Ventilation Associated With Inhaled Nitric Oxide in Children
Background/Objectives: Acute hypoxemic respiratory failure (AHRF) is a frequent cause of pediatric ICU admission. Early treatment with inhaled nitric oxide (iNO) plus conventional mechanical ventilation (CMV) improves…
- Trial name
- NCT00924846
- Testing
- High frequency oscillatory ventilation
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Pulmonary Disease, Chronic Obstructive
A Study to Assess the Safety and Pharmacokinetics of Inhaled Doses of GSK233705 and GW642444 in Healthy Subjects
GW642444 and GSK233705 are in development for treatment of Chronic Obstructive Pulmonary Disease. Development of these two inhaled drugs as a combination therapy would have potential for improved patient benefit as they both work…
- Trial name
- NCT00783003
- Testing
- GSK233705 and GW642444, GW642444, GSK233705
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Herpes Zoster
A Study to Evaluate the Safety and Immunogenicity of ChAdOx1-VZV in Healthy Adults Aged 50-65 Years
This is a randomized, observer blind and controlled study. Participants in low-dose and high-dose IM group will be randomized in a ratio of 2:1 to receive either the investigational product or the control.
- Trial name
- NCT05991427
- Testing
- Recombinant Zoster Vaccine (Adenovirus Vector) (ChAdOx1-VZV), Zoster Vaccine Recombinant, Adjuvanted (Shingrix), ChAdOx1-VZV
- Where
- Canada
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- CanSino Biologics Inc.