Clinical trials: Respiratory Aspiration
Asthma
Singulair(R) In Asthma And Allergic Rhinitis (0476-383)
Effectiveness of adding montelukast to inhaled corticosteroids in adult subjects with both uncontrolled asthma and allergic rhinitis.
- Trial name
- NCT00545844
- Testing
- montelukast sodium
- Volunteers
- 313 people
- Sponsor
- Organon and Co
Alarm Fatigue in Intensive Care Unit Nurses, Psychological Well-Being in Intensive Care Unit Nurses
Effects of Relaxation, Mindfulness, and Breathing Therapy on Alarm Fatigue and Psychological Well-being in Intensive Care Nurses
The goal of this clinical trial is to compare the effects of the Benson Relaxation Technique, mindfulness-based stress reduction meditation, and breathing therapy on reducing alarm fatigue and improving psychological well-being…
- Trial name
- NCT07124364
- Testing
- Benson Relaxation Technique, Mindfulness-Based Stress Reduction Meditation, Breathing Therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 168 people
- Sponsor
- Hacer Eroglu
Intraoral Tumor
Differences in Speed of Recovery From Anesthesia for Intraoral Surgery
The goal of this clinical trial is to compare two groups of patients going in general anesthesia for intraoral surgery, the first group TIVA with propofol and the second group inhalational with sevoflurane.
- Trial name
- PSIOS (NCT06275087)
- Testing
- Propofol, Sevoflurane
- Where
- Croatia
- Volunteers
- 42 people
- Sponsor
- Clinical Hospital Centre Zagreb
Primary Open Angle Glaucoma, Hypertension
Alternate Nostril Breathing Training in Geriatrics With Glaucoma and High Blood Pressure
Hypertension, particularly if poorly controlled, appears related to an increased risk of open angle glaucoma, (the high tension type of glaucoma is characterized as optic nerve degeneration with ocular hypertension).
- Trial name
- NCT05605743
- Testing
- breathing exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Healthy
Respiratory Muscle Fatigue at Different Breathing Modes
The study aims at investigating if time to respiratory muscle fatigue and metabolism are influenced by the pressure wave form mode applied during resistive breathing.
- Trial name
- NCT05393115
- Testing
- Square wave breathing
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Asthma
A Study to Investigate the Safety, Tolerability and Effects of AZD8630 in Healthy Subjects and Subjects With Asthma on Inhaled Corticosteroids and Long-acting Beta-agonists
This is a first in human (FIH) clinical study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of AZD8630 in healthy adults (Part A) and adult asthma patients on medium to high dose inhaled…
- Trial name
- NCT05110976
- Testing
- AZD8630
- Where
- 29 sites in United States, Germany and 1 more
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Pulmonary Disease, Chronic Obstructive
Safety, Tolerability and Pharmacokinetics (PK) Study of GSK2269557 in Healthy Subjects
GSK2269557 is being developed as an anti-inflammatory and anti-infective agent for the treatment of inflammatory airways diseases.
- Trial name
- NCT03189589
- Testing
- GSK2269557 500 µg, GSK2269557 750 µg
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Asthma
Efficacy of Ciclesonide Versus Placebo Administered Either as Once Daily or Twice Daily in Patients Treated Previously With an Inhaled Corticosteroid
To investigate the efficacy of ciclesonide MDI either as once daily or a twice daily regimen in patients with mild to moderate asthma, who have previously been treated with an inhaled corticosteroid.
- Trial name
- NCT00174733
- Testing
- Ciclesonide (XRP1526)
- Where
- United States
- Volunteers
- 456 people
- Sponsor
- Sanofi
Respiratory Monitoring, Thoracic Surgery
AirGo™ Respiratory Monitoring in Lung Resection
Patients undergoing lung resection surgery may experience changes in respiratory function during the perioperative period. Current monitoring methods provide important clinical information but are often limited to specific time…
- Conditions
- Respiratory Monitoring, Thoracic Surgery, Lung Resection Surgery, Respiratory Function
- Trial name
- NCT07838025
- Testing
- AirGoTM system
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Eisenmenger Syndrome, Congenital Heart Disease
Sleep-disordered Breathing in Eisenmenger Syndrome
Sleep-disordered breathing (SDB) is a wellknown comorbidity in cardiovascular disease. Knowledge about SDB in adult congenital heart disease is limited.
- Conditions
- Eisenmenger Syndrome, Congenital Heart Disease, Sleep-disordered Breathing
- Trial name
- NCT02614417
- Testing
- Polysomnography
- Volunteers
- 20 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Sternotomy
The Benefit of Preparation in Respiratory Physiotherapy Before a Sternotomy in the Context of Cardiac Surgery
The sternotomy has some influence on the respiratory system after cardiac surgery, considerably increasing the risk of perioperative and postoperative breathing.
- Trial name
- NCT06153550
- Testing
- preparation in Respiratory Physiotherapy
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Sleep Apnea
Sleep-disordered Breathing in Postmenopausal Women
The purpose of this study is to investigate the effectiveness of CPAP treatment to co-morbidities of sleep apnea by looking the change of the consumption of medication of the co-morbidities before and after starting the CPAP…
- Trial name
- NCT01825291
- Testing
- CPAP treatment
- Volunteers
- 800 people
- Sponsor
- Turku University Hospital
Septic Shock
Comparison of Extubation Delay After Prolonged Sedation
This monocentric, prospective, controlled, randomized, single-blind study will be conducted in surgical resuscitation at the Rouen University Hospital.
- Trial name
- ISOREA (NCT04710914)
- Testing
- Prolonged sedation with isoflurane, Prolonged sedation with midazolam
- Where
- France
- Volunteers
- 1 people
- Sponsor
- University Hospital, Rouen
Cardiopulmonary Failure, Myocardial Infarction (MI)
COR-INSIGHT: Optimizing Cardiovascular and Cardiopulmonary Outcomes with AI-Driven Multiplexed Indications Using COR ECG Wearable
The COR-INSIGHT trial aims to evaluate the effectiveness of Peerbridge COR advanced ambulatory ECG wearables (COR 1.0 and COR 2.0) in accurately and non-invasively detecting cardiovascular and cardiopulmonary conditions using…
- Conditions
- Cardiopulmonary Failure, Myocardial Infarction (MI), Heart Decompensation, Heart Failure
- Trial name
- COR-INSIGHT (NCT06763549)
- Testing
- SUBPROTOCOL A, SUBPROTOCOL B, SUBPROTOCOL C
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Peerbridge Health, Inc
Temporomandibular Joint Dysfunction, Myofunctional Therapy
Temporomandibular Joint Respiratory and Thoracic Region Added to Myofunctional Rehabilitation in Dysfunction Comparison of the Effects of Exercises
In the study, a questionnaire form will be applied to the participants using a face-to-face interview technique. Through the questionnaires, demographic characteristics, pain intensity, location of pain, symptoms of dysfunction…
- Conditions
- Temporomandibular Joint Dysfunction, Myofunctional Therapy, Rehabilitation Exercise
- Trial name
- NCT06883825
- Testing
- Myofunctional Therapy, Myofunctional Therapy + Respiratory Exercises, Myofunctional Therapy + Thoracic Region Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Merve Keskin
Healthy
Pharmacokinetics & Tolerability Study of MAP0004 Co-administered With Ketoconazole
Compare the DHE pharmacokinetic profiles observed following administration of: 1. MAP0004 (oral inhalation DHE) 2. MAP0004 co-administered with oral Ketoconazole 3.
- Trial name
- NCT01468558
- Testing
- MAP0004, IV DHE, Ketoconazole
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Allergan
Breathing-Swallowing Coordination, Dysphagia Rehabilitation
Visual and Auditory Breathing-swallowing Coordinated Training
Dysphagia is caused by multiple factors, and respiratory-swallowing discoordination is considered to be one of the factors. The investigators recently developed a visual and auditory breathing-swallowing coordinated training…
- Trial name
- NCT04590391
- Testing
- Visual and Auditory Breathing-swallowing Coordinated Training device
- Where
- Japan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Hospital Organization Minami Kyoto Hospital
Postoperative Respiratory Complication
Effect of Preoperative Incentive Spirometer on Postoperative Pulmonary Complications Following Lung Resection
The objective of this study is to demonstrate that inspiratory muscle training with daily use of an incentive spirometer for at least 14 days prior to lung surgery will reduce the risk of post-operative pulmonary complications.
- Trial name
- NCT04732143
- Testing
- Inspiratory muscle training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Hypertension
Effectiveness of Inspiratory Muscle Training With Slow Breathing in Elderly With ISH
Study the effects of inspiratory muscle training at Low load of 25 %Maximal inspiratory pressure with slow breathing rate at 6 breaths/min on inspiratory muscle strength, lung function, chest wall expansion, abdominal expansion…
- Trial name
- NCT02752217
- Testing
- Inspiratory Muscle Training, Control
- Where
- Thailand
- Volunteers
- 32 people
- Sponsor
- Khon Kaen University
Asthma (Diagnosis), Breathing Exercises
Comparative Effect of Box Breathing And Buteyko Breathing on Pulmonary Functions in Asthma
The aim of this study was to evaluate the Effectiveness of Box Breathing Technique and Buteyko breathing techniques in patients with Asthma, using both Clinical Pulmonary tests as well as Patient reported outcomes.
- Trial name
- NCT07140458
- Testing
- Buteyko Breathing, Box breathing
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
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