Clinical trials: Respiratory Distress Syndrome, Newborn
Acute Respiratory Distress Syndrome (ARDS)
Safety Study of Inhaled Carbon Monoxide to Treat Acute Respiratory Distress Syndrome (ARDS)
The purpose of this study is to assess the safety of inhaled carbon monoxide (iCO) in intubated patients with sepsis-induced ARDS.
- Trial name
- NCT02425579
- Testing
- Inhaled Carbon Monoxide at 100ppm (4 participants), Inhaled Carbon Monoxide at 200ppm (4 participants)
- Where
- 4 sites in United States
- Volunteers
- 12 people
- Sponsor
- Brigham and Women's Hospital
Acute Respiratory Distress Syndrome Caused by COVID-19
Efficacy of Dexamethasone Treatment for Patients With ARDS Caused by COVID-19
Background: There are no proven therapies specific for Covid-19. The full spectrum of Covid-19 ranges from asymptomatic disease to mild respiratory tract illness to severe pneumonia, acute respiratory distress syndrome (ARDS)…
- Trial name
- DEXA-COVID19 (NCT04325061)
- Testing
- Dexamethasone
- Where
- 24 sites in Spain
- Volunteers
- 19 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Acute Respiratory Distress Syndrome, Capnography
Dead Space Monitoring With Volumetric Capnography in ARDS Patients
This studies´ objective is to describe how different PEEP levels affect dead space measured by Bohr´s formula.
- Trial name
- NCT02889770
- Testing
- PEEP titration
- Volunteers
- 10 people
- Sponsor
- Hospital Italiano de Buenos Aires
Acute Respiratory Distress Syndrome
Electrical Impedance Tomography for Quantification of Pulmonary Edema in Acute Respiratory Distress Syndrome Patients
Evaluation of pulmonary edema is a key factor in monitoring and guidance of therapy in acute respiratory distress syndrome (ARDS) patients.
- Trial name
- NCT02870894
- Where
- China
- Volunteers
- 22 people
- Sponsor
- Sichuan Provincial People's Hospital
Maternal Attachment, Breastfeeding
Reciprocal Mother-Infant Voice Exposure in the Neonatal Intensive Care Unit
This randomized controlled trial evaluates the effect of reciprocal maternal-infant voice exposure on maternal attachment and breastfeeding outcomes in a neonatal intensive care unit (NICU).
- Conditions
- Maternal Attachment, Breastfeeding, Transient Tachypnea of the Newborn, Neonatal Intensive Care Unit
- Trial name
- NCT07597954
- Testing
- Reciprocal Voice Exposure Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Biruni University
Acute Respiratory Distress Syndrome (ARDS), Acute Lung Injury(ALI)
A Study on the Treatment of Patients With Acute Lung Injury Caused by Sepsis Through Microbiota Transplantation
Sepsis is a systemic inflammatory response syndrome triggered by infection, and it is a common critical illness in clinical practice, often leading to multiple organ dysfunction.
- Conditions
- Acute Respiratory Distress Syndrome (ARDS), Acute Lung Injury(ALI), Sepsis Related Acute Lung Injury/Acute Respiratory Distress Syndrome
- Trial name
- NCT07342205
- Testing
- Human-derived active intestinal bacterial liquid group
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Acute Respiratory Distress Syndrome
Noninvasive Positive Pressure Ventilation in Moderate Acute Respiratory Distress Syndrome
In order to identify the effect of noninvasive positive pressure ventilation (NPPV) on decreasing inflammatory response, improving the pathophysiological manifestation and reducing the morbidity and mortality in the moderate…
- Trial name
- NCT01585922
- Testing
- noninvasive positive pressure ventilation (NPPV), invasive mechanical ventilation
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Beijing Hospital
Respiratory Insufficiency, Respiratory Distress Syndrome, Adult
Continuous Positive Airway Pressure (CPAP) Ventilation Using a Novel Full-Face Mask Versus Conventional Helmet
The aim of this study is to compare two methods of delivery of noninvasive mechanical ventilation (NIV). Since patient compliance and mechanical characteristics of the delivery devices are two fundamental variables in the success…
- Conditions
- Respiratory Insufficiency, Respiratory Distress Syndrome, Adult, Chronic Obstructive Pulmonary Disease, Pulmonary Edema
- Trial name
- NCT00944437
- Testing
- Helmet, Full-face mask
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- University of Parma
Severe Acute Respiratory Syndrome Coronavirus 2
Vagus Nerve Stimulation ARDS Prevention Trial for COVID-19 Hospitalized Patients
This trial is designed to determine if the inflammation modulating effect of vagus nerve stimulation can improve pulmonary function and limit progression to ARDS in hospitalized COVID-19 hospitalized patients.
- Trial name
- NCT04379037
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- Argentina
- Volunteers
- 50 people
- Sponsor
- Nemechek Technologies
COVID - 19, Acute Respiratory Distress Syndrome (ARDS)
Prone Duration in COVID-19 ARDS
The aim of this observational study is to learn the effects of prone position duration on patient outcomes in patients with severe acute respiratory distress syndrome (ARDS) due to Coronavirus Disease - 2019 (COVID-19).
- Trial name
- PRODUR-CARDS (NCT06765759)
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people
- Sponsor
- Istanbul University - Cerrahpasa
ARDS, Human
Regional Assessment of the Risk of Lung Injury in Ventilated Patients
Specific characteristics of the lung, such as its functional capacity, heterogeneity, and recruitment potential, can influence the development of ventilator-induced lung injury even under safe ventilation conditions.
- Trial name
- RLY (NCT06486259)
- Testing
- Controlled mechanical ventilation
- Where
- Argentina
- Volunteers
- 10 people
- Sponsor
- Hospital El Cruce
Sever Chest Trauma, Mechanical Ventilation
Driving Pressure in Trauma
Traumatic chest injuries are responsible for significant morbidity and the cause of trauma-related death in 20%-25% of cases. Thoracic trauma can include multiple injuries, mainly osseous (ribs, sternal fractures, flail chest)…
- Trial name
- NCT03367442
- Testing
- no intervention
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Montpellier
Acute Lung Injury, Acute Respiratory Distress Syndrome
Epidemiology Research on Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) in Adult ICU in Shanghai
To survey the prevalence and the mortality of the Acute Lung Injury/ Acute Respiratory Distress Syndrome (ALI/ARDS) in 12 university hospital ICUs in Shanghai.
- Trial name
- NCT01186874
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tongji University
ARDS, Prevention and Control
A Combination of an Inhaled Budesonide and Ipratropium in Patients at Risk of Developing ARDS
Acute respiratory distress syndrome (ARDS) is a severe lung condition with high morbidity and mortality, despite advances in medical care.
- Trial name
- BUDIPRA-ARDS (NCT06657079)
- Testing
- combined standard aerosolized doses of budesonide (0.5 mg/2 mL) every 12 hours and ipratropium bromide (500/2 mL) every eight hours for up to five days
- Where
- Egypt
- Volunteers
- 119 people
- Sponsor
- Damanhour University
ARDS, Acute Respiratory Distress Syndrome
Intravenous Imatinib in Mechanically Ventilated COVID-19 Patients
The SARS-CoV2 pandemic and resulting COVID-19 infection has led to a large increase in the number of patients with acute respiratory distress syndrome (ARDS).
- Conditions
- ARDS, Acute Respiratory Distress Syndrome, Covid19, Endothelial Dysfunction
- Trial name
- INVENT COVID (NCT04794088)
- Testing
- Imatinib Mesylate intravenous solution
- Where
- 2 sites in Netherlands
- Volunteers
- 67 people
- Sponsor
- Dr. Jurjan Aman
COVID-19, Mechanical Ventilation
Risk Factors for Prolonged Invasive Mechanical Ventilation in COVID-19 Acute Respiratory Distress Syndrome
This multicentric prospective clinical practice study aims at evaluating clinical factors associated with a prolonged invasive mechanical ventilation and other outcomes such as mortality and ICU length of stay in patients…
- Conditions
- COVID-19, Mechanical Ventilation, Quality of Life, Radiologic Increased Density of Lung
- Trial name
- NCT04411459
- Testing
- Invasive mechanical ventilation
- Where
- 20 sites in Italy
- Volunteers
- 470 people
- Sponsor
- Azienda Usl di Bologna
COVID-19 Acute Respiratory Distress Syndrome
Macintosh Versus Macgrath for Laryngoscopy in COVID 19 Hypoxemic ICU Patients
In this comparative prospective study, we aim to compare the classic Macintosh laryngoscope and the Mac Grath videolaryncoscope in ICU covid 19 patients recruiting intubation and invasive mechanical ventilation.
- Trial name
- NCT04956913
- Testing
- Mac Grath, Macintosh
- Volunteers
- 80 people
- Sponsor
- Mongi Slim Hospital
Infection With Coronavirus SARS-CoV2
Long Term Physical Functional Limitations in Daily Living in SARS-CoV2 Infected Patients Hospitalized in the Acute Phase Then Requiring Rehabilitation
Infection with coronavirus SARS-CoV2 (COVID-19 disease) is unique with its speed of propagation, structural medical reorganizations and length of stay in intensive care needed, diversity of the affected population (in particular…
- Trial name
- CAPACoV19 (NCT04356378)
- Testing
- Data record
- Where
- France
- Volunteers
- 149 people
- Sponsor
- CHU de Reims
Acute Respiratory Distress Syndrome, Severe Acute Respiratory Syndrome
Streptokinase Versus Unfractionated Heparin Nebulization in Severe ARDS
Background: Intra-alveolar clotting and alveolar collapse in ARDS is due to alveolar capillaries epithelial and leakage. Subsequently, collapse induces hypoxemia that is resistant to recruitment (RM).
- Trial name
- NCT03465085
- Testing
- Unfractionated heparin, Streptokinase
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Acute Respiratory Distress Syndrome
Strain and Blood Inflammatory Markers as Prognostic Tools for ARDS AMIS (ARDS - Markers of Inflammation - Strain)
The objective is determine the strain measured at the bedside could be a dynamic prognostic marker of during Acute respiratory Distress Syndrome (ARDS).
- Trial name
- AMIS (NCT02003326)
- Testing
- Inflammatory markers
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
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