Clinical trials: Respiratory Distress Syndrome, Newborn
Acute Respiratory Distress Syndrome
The Effects of Different Ventilator Strategies on Inflammation and Injury in Normal Lungs
This research is being done to determine if there is a way the investigators can improve the techniques that they use to assist patients with their breathing during surgery.
- Trial name
- NCT01003730
- Testing
- Ventilator settings
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
COVID-19, Respiratory Distress Syndrome
Exogenous Surfactant Through Nebulizer Mask on Clinical Outcomes in Covid-19 Patients
Covid-19 disease is one of the most important health system challenges which is the result of the recent SARS CoV-2 virus outbreak.
- Conditions
- COVID-19, Respiratory Distress Syndrome, Surface-Active Agents
- Trial name
- CovidSurf (NCT04847375)
- Testing
- exogenous surfactant
- Volunteers
- 60 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Acute Respiratory Distress Syndrome, Ventilation Perfusion Mismatch
Change in the Phase III Slope of the Volumetric Capnography by Prone Positioning in Acute Respiratory Distress Syndrome
This study evaluates the effects of prone positioning on homogenization of ventilation.
- Conditions
- Acute Respiratory Distress Syndrome, Ventilation Perfusion Mismatch, Respiratory Failure
- Trial name
- NCT05535543
- Testing
- Prone Positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Acute Respiratory Distress Syndrome
Effect of PEEP Titration on the EELV Measured by the Nitrogen Dilution Technique in ARDS
Mechanical ventilation of the patient with acute respiratory distress syndrome is one of the first therapies.
- Trial name
- TIPEX-VOLTEX (NCT04352725)
- Testing
- End-expiratory lung volume measurement and incremental PEEP titration
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Intercommunal Aix-Pertuis
SARS-CoV Infection, Acute Respiratory Distress Syndrome
Electrical Impedance Tomography: Collapse in Dependent Areas as a Predictor of Response to Prone Position Ventilation in COVID-19 Acute Respiratory Distress Syndrome
There are several clinical presentations of SARS-CoV-2 infection. Among the severe forms, pulmonary involvement with respiratory failure is common.
- Trial name
- COVIDEIT (NCT04603755)
- Testing
- Electrical Impedance tomography
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- Direction Centrale du Service de Santé des Armées
Respiratory Distress Syndrome, Newborn, Infant, Premature
Neural Control of Non-invasive Ventilation in the Preterm
The present study will use a new type of respirator in premature babies who need help with their breathing. This new respirator uses signals from the baby's diaphragm - the most important breathing muscle - to control the timing…
- Trial name
- NCT00368485
- Testing
- Neurally Controlled Mechanical Ventilation
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Fibrinogen, Albumin
Fibrinogen-to-Albumin Ratio as a Predictor of Acute Respiratory Distress Syndrome in Traumatic Brain Injury
this study aims to assess the ability of fibrinogen-to-albumin ratio to predict the development of Acute respiratory distress syndrome in traumatic brain injury patients.
- Conditions
- Fibrinogen, Albumin, ARDS, TBI (Traumatic Brain Injury)
- Trial name
- FARDS (NCT07664358)
- Testing
- Fibrinogen-to-albumin ratio
- Where
- Egypt
- Volunteers
- 350 people
- Sponsor
- Tanta University
Respiratory Distress Syndrome, Newborn, Noninvasive Ventilation
RAM Cannula VS Short Nasal Prongs for Delivering NIPPV in Preterm Infants
Randomized control trial, Ram cannula VS short nasal prongs for delivering Non Invasive Positive Pressure Ventilation (NIPPV) for preterm infants
- Conditions
- Respiratory Distress Syndrome, Newborn, Noninvasive Ventilation, Infant, Premature, Intubation, Intratracheal
- Trial name
- RAMCAN (NCT03081611)
- Testing
- Ram cannula, Short nasal prongs
- Where
- Israel
- Volunteers
- 166 people
- Sponsor
- Rambam Health Care Campus
Respiratory Distress Syndrome
Facilitated Tucking Position During Endotracheal Suctioning
Aim of the present study The present study will aimed to determine the effect of facilitated tucking position during endotracheal suctioning on physiological criteria and behavioural responses of the preterm neonates.
- Trial name
- NCT06428916
- Testing
- tucking position during endotracheal suctioning
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Ventilation, Respiratory Distress Syndrome
Observational Crossover Study Comparing Oxygenation and Ventilation Using SiPAP Versus CPAP in LBW Infants
Investigation of effects of SiPAP versus NCPAP on oxygenation and ventilation in LBW infants with respiratory distress. Our hypothesis is that the LBW infants will achieve the same level of oxygenation and improved ventilation…
- Trial name
- NCT01053455
- Testing
- SiPAP
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Early Prediction for Sepsis Induced Acute Lung Injury
Radiomics Markers to Predict Sepsis Induced Acute Respiratory Distress Syndrome
Introduction: Sepsis-induced acute respiratory distress syndrome(SI-ARDS) is a common complication of severe sepsis and is an independent contributor to poor prognosis of patients.
- Trial name
- NCT04541264
- Testing
- radiomic of chest CT
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Acute Respiratory Distress Syndrome, COVID-19
Trans Thoracic Manipulation of Ventilation/Perfusion: the V/Q System
The purpose of this pilot study is to measure the impact of non-invasive pneumatic manipulation of transthoracic pressure on oxygenation in patients with Acute Respiratory Distress Syndrome (ARDS) due to Coronavirus Disease 2019…
- Trial name
- NCT04369599
- Testing
- V/Q System
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Emory University
COVID-19 Pneumonia, Thrombosis
Practice Variation on Antithrombotics in COVID-19
Evidence suggests coronavirus disease 2019 (COVID-19) is associated with an increased incidence of thromboembolic manifestations.
- Conditions
- COVID-19 Pneumonia, Thrombosis, COVID-19 Acute Respiratory Distress Syndrome, Severe Acute Respiratory Syndrome (SARS) Pneumonia
- Trial name
- NCT04998799
- Testing
- Current clinical practices of participating physicians
- Where
- India
- Volunteers
- 435 people
- Sponsor
- NMC Specialty Hospital
Preterm Labor With Preterm Delivery, Premature Birth
Pharmacokinetics and Placental Transfer of Caffeine
The goal of this study is to learn how a pregnant person's body processes caffeine and how much caffeine crosses the placenta to the baby. A small dose of caffeine will be given to each pregnant participant before delivery.
- Conditions
- Preterm Labor With Preterm Delivery, Premature Birth, Apnea of Prematurity, Respiratory Distress Syndrome
- Trial name
- AnteCaff (NCT07570121)
- Testing
- Caffeine citrate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Indiana University
Respiratory Distress Syndrome, Newborn
Fluid Restriction in Respiratory Distress of the Newborn
The object of this study is to determine the best way to care for infants with respiratory distress. The investigators are testing a method of feeding fluids to infants with respiratory distress in amounts similar to what healthy…
- Trial name
- NCT03120585
- Testing
- Fluid Management Intervention
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- University of Oklahoma
SARS-CoV Infection, Acute Respiratory Distress Syndrome
Glenzocimab in SARS-Cov-2 Acute Respiratory DistrEss syNdrome Related to COVID-19
A randomized, double blind, multicenter, placebo-controlled, parallel group, fixed dose, phase II study to evaluate the efficacy and safety of glenzocimab in ARDS.
- Conditions
- SARS-CoV Infection, Acute Respiratory Distress Syndrome, COVID-19, ARDS
- Trial name
- GARDEN (NCT04659109)
- Testing
- glenzocimab
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Acticor Biotech
Acute Respiratory Distress Syndrome, Lung Diseases
Fluids and Catheters Treatment Trial (FACTT) - ARDS Clinical Research Network
To assess rapidly innovative treatment methods in patients with adult respiratory distress syndrome as well as those at risk of developing ARDS.
- Trial name
- NCT00281268
- Testing
- pulmonary artery catheter, central venous catheter, fluid management
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Respiratory Distress Syndrome, Lower Respiratory Tract Infection
A Low-Resource Oxygen Blender Prototype for Use in Modified Bubble CPAP Circuits
Purpose: Using a novel oxygen blender prototype with modified bCPAP to manage children 1 month to 5 years of age hospitalized with respiratory distress due to lower respiratory tract infection (LRTI) in low-resource settings is…
- Trial name
- NCT04311320
- Testing
- Low-Resource Oxygen Blender
- Where
- Cambodia
- Volunteers
- 33 people
- Sponsor
- University of Minnesota
Neonatal Respiratory Distress Syndrome, Prematurity
Breathing Variability and NAVA in Neonates
The current study is a crossover trial, aiming at evaluating the effect of NAVA -NIV compared to Nasal Intermittent Positive Pressure Ventilation (PC-NIV) at the same level of peak inspiratory pressure, in terms of…
- Trial name
- BRAVe NANO (NCT04000568)
- Testing
- Respiratory support: NAVA -NIV and PC-NIV
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Sepsis, Acute Kidney Injury Due to Sepsis
Presepsin:Gelsolin Ratio in Sepsis-related Organ Dysfunction
In the present study, 126 patients were enrolled (23 control, 38 non-septic and 65 septic patients). Blood samples were collected from septic patients at the intensive care unit (ICU) at three time points (T1-3): T1: within 12h…
- Conditions
- Sepsis, Acute Kidney Injury Due to Sepsis, Septic Shock, Acute Respiratory Distress Syndrome
- Trial name
- NCT05060679
- Testing
- Supportive therapy at the ICU, Sepsis therapy, Sepsis-related organ dysfunction therapy
- Where
- Hungary
- Volunteers
- 126 people
- Sponsor
- University of Pecs
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