Clinical trials: Respiratory Distress Syndrome (RDS)
Adult Respiratory Distress Syndrome
Prevention of Lung Injury Induced by Mechanical Ventilation in Acute Respiratory Distress Syndrome ARDS Patients
Given the huge volume of mechanically ventilated patients at risk of ARDS, optimizing hematosis by limiting pulmonary and systemic aggression associated with artificial ventilation techniques is a key objective if we are to…
- Trial name
- PULMODEL (NCT06835881)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Prematurity, Respiratory Distress Neonatal
Effect of Automated Oxygen Control on Early-childhood Lung Mechanics
Preterm infants are at higher risk of long-term respiratory problems and abnormal lung function in childhood. Respiratory support including mechanical ventilation, that is the use of a machine to move air into and out of the…
- Conditions
- Prematurity, Respiratory Distress Neonatal, Oxygen Delivery
- Trial name
- NCT07866820
- Testing
- Forced oscillometry technique
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- King's College Hospital NHS Trust
Respiratory Distress Syndrome, Adult
Significance of Biological Markers in Patients With Acute Lung Injury/Acute Respiratory Disease
The purpose of this study is to identify biological markers of disease in patients with acute lung injury (ALI) that are predictive of either disease susceptibility or prognosis, or that identify novel targets of therapeutic…
- Trial name
- NCT00217880
- Testing
- Bronchoscopy
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Respiratory Distress Syndrome, Pneumothorax/Pulmonary Intersticial Emphysema
Very Early Surfactant and NCPAP for Premature Infants With RDS
The present study will test the use of very early nasal continuous airway pressure(NCPAP)with and without surfactant in premature infants with clinical evidence or respiratory distress syndrome.
- Conditions
- Respiratory Distress Syndrome, Pneumothorax/Pulmonary Intersticial Emphysema, Chronic Lung Disease
- Trial name
- CNRNCPAP (NCT00563641)
- Testing
- Very early surfactant and bubble NCPAP, bubble NCPAP
- Where
- Colombia
- Volunteers
- 278 people
- Sponsor
- Colombian Neonatal Research Network
Acute Lung Injury, Respiratory Distress Syndrome, Adult
Measuring Energy Expenditure in ECMO (Extracorporeal Membrane Oxygenation) Patients
With the perception that lung protective ventilation with regard to low tidal volume ventilation and limiting airway pressures improves outcome in ARDS (acute respiratory distress syndrome) and that the development of new…
- Trial name
- MEEP (NCT01992237)
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Charite University, Berlin, Germany
ARDS (Acute Respiratory Distress Syndrome)
Observational, Non-interventional Biomarker and Endotyping Study
The goal of this observational study is to establish a centralized ARDS biorepository of longitudinal biospecimens and harmonized clinical data, develop unsupervised, therapy-agnostic endotyping algorithms, and develop…
- Trial name
- OBSERVE-ARDS (NCT07675265)
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Prenosis, Inc.
ARDS, Human, Endothelial Dysfunction
Glycocalyx Biomarkers in ARDS for Clinical Prognosis and Pulmonary Fibrosis
ARDS is a severe disease in ICU, and could induce high mortality. Glycocalyx is an important matrix construction which covers endothelial cells, it could protect endothelial cells injury and the glycocalyx biomarkers could…
- Conditions
- ARDS, Human, Endothelial Dysfunction, Mechanical Ventilation Pressure High
- Trial name
- NCT03854565
- Testing
- Glycocalyx measurement，respiratory mechanics measurement
- Where
- China
- Volunteers
- 336 people
- Sponsor
- Southeast University, China
Acute Respiratory Distress Syndrome, COVID-19 Respiratory Infection
Evaluation of the Efficiency and Complications of the Consequtive Proning in Covid -19 ICU
Thirty -one confirmed Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2 ) infected patients with Acute Respiratory Distress Syndrome (ARDS) and placed in prone position(PP) for 3 times (PP1, PP2, PP3)consecutively will…
- Trial name
- NCT05387356
- Testing
- prone position
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Kecioren Education and Training Hospital
Respiratory Distress Neonatal, Noninvasive Ventilation
Comparison of the Silverman-Andersen Score and the Downes Score
This study aimed to compare the Silverman-Andersen score and the Downes score in predicting noninvasive ventilation (NIPPV) failure in preterm and term infants who received NIPPV support due to postnatal respiratory distress, as…
- Conditions
- Respiratory Distress Neonatal, Noninvasive Ventilation, Intubation, Scoring Systems
- Trial name
- CSASDS (NCT07183956)
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 220 people
- Sponsor
- Muğla Sıtkı Koçman University
ARDS, Human
Functional Respiratory Imaging of Airways in ARDS
This is a prospective single-center cohort trial to compare regional bronchial recruitment, bronchial distention and alveolar recruitment in 6 patients with acute respiratory distress syndrome (ARDS).
- Trial name
- NCT03309085
- Testing
- Repeated CT scan, CT scan
- Where
- Belgium
- Volunteers
- 7 people
- Sponsor
- University Hospital, Antwerp
Acute Lung Injury
Hemodynamics and Extravascular Lung Water in Acute Lung Injury
The purpose of this study is to test a treatment that tries to reduce the amount of fluid in the lungs of subjects with acute lung injury to see if this is helpful.
- Trial name
- HEAL (NCT00624650)
- Testing
- Diuresis (furosemide) part I, Fluid Bolus (crystalloid or albumin), Vasopressors (Norepinephrine, Vasopressin, Phenylephrine, Epinephrine)
- Where
- 3 sites in United States
- Volunteers
- 33 people
- Sponsor
- Oregon Health and Science University
ARDS, Human
Effect of Electric Impedance Tomography-Guided PEEP Titration
Acute respiratory syndrome distress (ARDS) is a clinical common syndrome with high mortality. Mechanical ventilation (MV) is the cornerstone of management of ARDS but can lead to ventilator-induced lung injury.
- Trial name
- NCT05736185
- Testing
- PEEP selection
- Where
- China
- Volunteers
- 69 people
- Sponsor
- Southeast University, China
Severe Acute Respiratory Distress Syndrome, Refractory Hypoxemia
ECMO for Critically Ill Patients With Respiratory Failure and/or Circulatory Failure
Extracorporeal membrane oxygenation (ECMO) had been used to treat refractory hypoxemia associated with acute respiratory distress syndrome (ARDS).
- Trial name
- NCT04031794
- Testing
- Extra Corporeal Membrane Oxygenator (ECMO)
- Where
- Thailand
- Volunteers
- 250 people
- Sponsor
- Mahidol University
Infant, Newborn, Diseases, Prematurity
Prophylactic Surfactant by Thin Endotracheal Catheter for Preterm Infants At Birth: the ProTeCt Trial
The goal of this clinical trial is to learn whether giving surfactant through a thin endotracheal catheter to extremely premature babies shortly after birth reduces the number of them who are ventilated in the first 3 days of…
- Conditions
- Infant, Newborn, Diseases, Prematurity, Prematurity; Extreme, Respiratory Distress Syndrome in Premature Infant
- Trial name
- proTeCt (NCT06557551)
- Testing
- Thin catheter surfactant
- Where
- Ireland
- Volunteers
- 164 people
- Sponsor
- University College Dublin
Acute Respiratory Distress Syndrome (ARDS), Cardiogenic Shock
Cerebral Autoregulation in Pediatric ECMO (ECMOX 2)
Children supported by Extra-Corporeal Membrane Oxygenation (ECMO) present a high risk of neurological complications and cerebral autoregulation (CA) impairment may be a risk factor.
- Conditions
- Acute Respiratory Distress Syndrome (ARDS), Cardiogenic Shock, Cardiac Arrest
- Trial name
- ECMO-ECMOX2 (NCT04548739)
- Where
- 4 sites in France, Italy
- Volunteers
- 132 people
- Sponsor
- Nantes University Hospital
Acute Respiratory Distress Syndrome
Discovery of New Early Detection Biomarkers of Acute Respiratory Distress Syndrome
The goal of this project is to find a series novel biomarkers by differential proteomic techniques that can improve the early diagnosis and develop a more efficient therapy to enhance ARDS patient survival rate.
- Trial name
- ARDS (NCT02625064)
- Testing
- Blood samples collection before treatment, Blood samples collection after treatment, laboratory biomarker proteomic analysis
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Xiangya Hospital of Central South University
Respiratory Distress Syndrome
Verification of Pulse Oximetry in Neonatal Population
The purpose of this his post-market, observational study titled Verification of Pulse Oximetry in the Neonatal Population is to gather data to further support the accuracy of Nonin's pulse oximeters when used in the neonate…
- Trial name
- NCT00751439
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Acute Respiratory Distress Syndrome
Very Low Tidal Volume vs Conventional Ventilatory Strategy for One-lung Ventilation in Thoracic Anesthesia
The purpose of this study is to determine if a protective ventilatory strategy during one-lung ventilation (OLV) based on low tidal volume, PEEP and alveolar recruitment maneuver can reduce Acute Respiratory Distress Syndrome…
- Trial name
- NCT01504893
- Testing
- Protective one lung ventilation
- Where
- 16 sites in Italy
- Volunteers
- 984 people
- Sponsor
- Azienda Ospedaliera S. Maria della Misericordia
Newborn Rds, Transient Tachypnea of the Newborn
LUNG ULTRASONOGRAPHY DECREASES RADIATION EXPOSURE
We aimed to decrease in the number of chest X-rays in newborns with respiratory distress, with the use of lung ultrasonography. From January 2019 to June 2020, 104 newborn infants with respiratory distress enrolled in this study.
- Conditions
- Newborn Rds, Transient Tachypnea of the Newborn, Pneumonia
- Trial name
- LUDRE (NCT04722016)
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Hacettepe University
Acute Lung Injury, Acute Respiratory Distress Syndrome
Acute Lung Injury in Children: Epidemiology and Natural History. PEDIATRIC ALIEN.
The investigators propose to perform a one-year prospective audit of all Acute lung injury (ALI)and cute respiratory distress syndrome (ARDS) pediatric patients managed in several ICUs in Spain.
- Trial name
- ALIEN (NCT01131598)
- Where
- Spain
- Volunteers
- 1 people
- Sponsor
- Hospital de Cruces
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.