Clinical trials: Respiratory Distress Syndrome (RDS)
COVID-19, Acute Respiratory Distress Syndrome
Physical Rehabilitation in ICU in ARDS Patients With COVID-19
The primary aim of this study is to evaluate the effect of physical rehabilitation performed in intensive care unit on the range of joint motions and muscle strength of survivors following discharge from intensive care unit in…
- Conditions
- COVID-19, Acute Respiratory Distress Syndrome, Rehabilitation, Intensive Care Unit Acquired Weakness
- Trial name
- NCT04435080
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Koç University
Acute Respiratory Distress Syndrome, Delirium
Cognitive Dysfunctions Associated With Delirium in Critically-ill ARDS Patients
Early cognitive assessment of critically-ill acute respiratory distress syndrome (ARDS) patients with delirium using a multidimensional electrophysiological evaluation battery (mEEG) to identify and characterize the neural…
- Trial name
- DeSign (NCT06206473)
- Testing
- mEEG assessment
- Sponsor
- University Hospital, Toulouse
ARDS (Acute Respiratory Distress Syndrome)
EIT Evaluation of the Impact of Inhaled Nitric Oxide on Ventilation/Perfusion Mismatch in ARDS Patients Receiving Noninvasive Respiratory Support
This study aimed to quantitatively evaluate the immediate effect of inhaled nitric oxide on the ventilation / perfusion ratio in ARDS patients receiving nasal high flow oxygen therapy or noninvasive ventilation using electrical…
- Trial name
- NCT07617298
- Testing
- Inhale different doses of nitric oxide
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Ming Zhong
Respiratory Distress Syndrome (& [Hyaline Membrane Disease]), Bronchopulmonary Dysplasia (BPD)
Combined Oscillation-Volume guarantEe Study
Respiratory Distress Syndrome (RDS) remains the most common respiratory complication in the early postnatal period among preterm infants born before 32 weeks' gestational age.
- Trial name
- NCT07377955
- Testing
- HFOV, HFOV+VG
- Volunteers
- 348 people
- Sponsor
- Xingwang Zhu
Complication of Surgical Procedure, Acute Respiratory Failure, Adult
Prospective Evaluation of a RIsk Score for Postoperative Pulmonary COmPlications in Europe
Prospective Evaluation of a RIsk Score for postoperative pulmonary COmPlications in Europe (PERISCOPE) is a multi-centre, international observational study of a random-sample cohort of patients undergoing a nonobstetric…
- Conditions
- Complication of Surgical Procedure, Acute Respiratory Failure, Adult, Postoperative Respiratory Complications, Pulmonary Failure
- Trial name
- PERISCOPE (NCT01346709)
- Where
- 63 sites in Albania, Belgium and 19 more
- Volunteers
- 5,450 people
- Sponsor
- European Society of Anaesthesiology
Respiratory Distress Syndrome, Newborn
RAM Cannula Versus Short Bi-nasal Cannula in Respiratory Distress Syndrome
Noninvasive ventilation defines methods of providing ventilation support with constant or variable pressure using nasal or nasopharyngeal interfaces without endotracheal intubation or tracheostomy.
- Trial name
- NCT03366714
- Testing
- nasal CPAP support with RAM cannula, nasal CPAP support with Hudson cannula
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Inonu University
Respiratory Distress Syndrome, Pediatric, Altitude Hypoxia
Altitude and Outcomes in Pediatric ARDS: A Multicenter Study
This multicenter observational study will evaluate the association between geographic altitude, availability of critical care resources, and clinical outcomes in children with pediatric acute respiratory distress syndrome…
- Conditions
- Respiratory Distress Syndrome, Pediatric, Altitude Hypoxia, High Altitude Effects
- Trial name
- LARed-ALT (NCT07193771)
- Testing
- Geographic Altitude
- Where
- 20 sites in Bolivia, Chile and 3 more
- Volunteers
- 1,600 people
- Sponsor
- Latin American Pediatric Collaborative Network
Respiratory Distress Syndrome, Bronchopulmonary Dysplasia
NCPAP + Heliox as a Treatment for Infant Respiratory Distress Syndrome (RDS)
Infants born between 28 and 32 weeks' gestation with radiological findings and clinical symptoms of moderate RDS, requiring respiratory support with Nasal Continuous Positive Airway Pressure (NCPAP) within the first hour of life…
- Trial name
- NCT01383850
- Testing
- NCPAP + standard air, NCPAP + Heliox
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Acute Respiratory Distress Syndrome (ARDS)
Study of Xuanbai Shengmai Decoction in the Treatment of Acute Respiratory Distress Syndrome
Acute respiratory distress syndrome (ARDS) is a common clinical syndrome in the ICU characterized by extremely high mortality and complex pathogenesis.At present, research on individualized treatment, phenotypic differences, and…
- Trial name
- NCT07528196
- Testing
- Xuanbai Shengmai Decoction
- Volunteers
- 308 people
- Sponsor
- Southeast University, China
Respiratory Distress Syndrome, Adult, COVID-19
Dexamethasone Treatment for Severe Acute Respiratory Distress Syndrome Induced by COVID-19
Single blind randomized clinical trial designed to evaluate the efficacy of the combination of hydroxychloroquine and dexamethasone as treatment for severe Acute Respiratory Distress Syndrome (ARDS) related to coronavirus disease…
- Trial name
- DHYSCO (NCT04347980)
- Testing
- Dexamethasone and Hydroxychloroquine, Hydroxychloroquine
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Respiratory Distress Syndrome in Premature Infant
The Role of Circuit Flow During Mechanical Ventilation of Neonates
During neonatal mechanical ventilation inflating pressures, tidal volumes, and inflation and expiration times need to be set and adjusted to optimise oxygenation and carbon dioxide removal.
- Trial name
- E-Flow (NCT03306524)
- Testing
- SIPPV_VG_0_08, SIPPV_VG_0_16, SIPPV_VG_0_24
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Perinatal Death, Respiratory Distress Syndrome, Newborn
Maternal Hyperoxygenation for Intrapartum Fetal Heart Rate Tracing Abnormalities
Hyperoxygenation for resuscitation of abnormal fetal heart rate tracings has been routine obstetric practice. However, there have not been any studies to support this practice.
- Conditions
- Perinatal Death, Respiratory Distress Syndrome, Newborn, Hypoxic-Ischemic Encephalopathy, Neonatal Seizure
- Trial name
- NCT03996317
- Testing
- Room air
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Loma Linda University
Acute Respiratory Distress Syndrome
ASpirin as a Treatment for ARDS (STAR): a Phase 2 Randomised Control Trial
Acute Respiratory Distress Syndrome (ARDS) causes the lungs to fail due to the collection of fluid in the lungs (pulmonary oedema).
- Trial name
- STAR (NCT02326350)
- Testing
- Aspirin 75mg, Lactose powder
- Volunteers
- 49 people
- Sponsor
- Belfast Health and Social Care Trust
Respiratory Distress Syndrome
Study of Energy Requirements in Critically Ill Newborns
OBJECTIVES: I. Determine the total energy expenditure in term and preterm infants in both well and ill states using the doubly labeled water method.
- Trial name
- NCT00006274
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Respiratory Distress Syndrome, Newborn, Infant, Newborn
Feasibility of Uninterrupted Infant Respiratory Support Treatment
Feasibility study of a simplified respiratory support system for newborn infants
- Conditions
- Respiratory Distress Syndrome, Newborn, Infant, Newborn, Respiratory Insufficiency Syndrome of Newborn
- Trial name
- FUIRST (NCT04244890)
- Testing
- Uninterrupted CPAP for the first hours of life
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Karolinska Institutet
Prone Position, Acute Respiratory Distress Syndrome
Prone Position With Different Types of Cushions in Patients With ARDS
The prone maneuver is a well-established therapy in ARDS. Traditionally, the maneuver is perform with thoraco-abdominal cushions.
- Trial name
- PronEIT (NCT06184490)
- Testing
- Prone position with thoraco-abdominal cushion
- Where
- Brazil
- Volunteers
- 12 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Pediatric Acute Respiratory Distress Syndrome, Desflurane
Effect of Desflurane on Pediatric Acute Respiratory Distress Syndrome After Living Donor Liver Transplant Recipients
Biliary atresia is a serious congenital anomaly characterized by persistent and progressive cholestatic jaundice. The incidence of biliary atresia is more common in East Asia, especially China, with an incidence of 2 per 10,000…
- Conditions
- Pediatric Acute Respiratory Distress Syndrome, Desflurane, Biliary Atresia
- Trial name
- EDPARDSLDLTR (NCT05783518)
- Testing
- desflurane, propofol
- Where
- 2 sites in China
- Volunteers
- 165 people
- Sponsor
- Tianjin First Central Hospital
Acute Respiratory Distress Syndrome
Assessment of Acute Respiratory Distress in Children Presenting to the Emergency Department: Clinical, Epidemiological, and Etiological Insights
This study investigates the clinical and epidemiological characteristics of children with acute respiratory distress presenting to the emergency unit at Assiut University Children Hospital.
- Trial name
- NCT07149389
- Volunteers
- 70 people
- Sponsor
- Assiut University
Acute Respiratory Distress Syndrome, Hypoxemic Respiratory Failure
Treatment of Hypoxemic Respiratory Failure and ARDS With Protection, Paralysis, and Proning (TheraPPP) Pathway
Treatment of patients with Hypoxemic respiratory failure (HRF) and Acute Respiratory Distress Syndrome (ARDS) is complex. Therapies that have been shown to save the lives of patients with HRF and ARDS are available but they are…
- Conditions
- Acute Respiratory Distress Syndrome, Hypoxemic Respiratory Failure, ARDS, Human
- Trial name
- TheraPPP (NCT04070053)
- Testing
- TheraPPP Pathway
- Where
- Canada
- Volunteers
- 920 people
- Sponsor
- University of Calgary
Respiratory Failure, Hypoxemia
Application of Indicator Based-electrical Impedance Tomography Method Assess Lung Regional Perfusion in ICU Patients
This study is an observational study. Investigate the relationship of oxgenation and lung regional ventilation and perfusion assessed by the indicator based-EIT method in the critically ill patients in ICU
- Conditions
- Respiratory Failure, Hypoxemia, ARDS, Human
- Trial name
- NCT04081142
- Where
- China
- Volunteers
- 119 people
- Sponsor
- Yun Long
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